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The map label for this gene is rdgB [C]

Identifier: 197117593

GI number: 197117593

Start: 1399208

End: 1399813

Strand: Direct

Name: rdgB [C]

Synonym: Gbem_1205

Alternate gene names: 197117593

Gene position: 1399208-1399813 (Clockwise)

Preceding gene: 197117592

Following gene: 197117594

Centisome position: 30.32

GC content: 64.85

Gene sequence:

>606_bases
ATGAAAGAGCTCCTGGTAGCGTCGGGGAACAAGGGGAAGCTGCGCGAATTCGAGAAGCTTTTGGAGGGGGTGGTGGAGAC
CATCCTCTCCCCTGCCGACTTCCCGGGGCTTCCGGAGGTGGAGGAGGACGGCGACAGCTTCGAGGCGAACGCCCTGAAAA
AGGCCCGCTCCGCCGCGCTCTTCACCGGTAAACCGGTTCTGTCCGACGACTCCGGGCTCTGCGTCGACCACCTTGGAGGG
CGCCCCGGCGTCTACTCGGCGCGCTTTGCCGGAGAGGGGGCCGGGGACGCCGCCAACAACGCGCGCCTCTTGCAGGAAAT
GGCCGGAGTGCCGCGCGAAGAGCGCACCGGCGCCTTCCACTGCGTCATCGCCCTTTGCCTCCCAGACGGAAGCTGCCAGA
CCTTCGACGGCATGCTAAAGGGGGAGATACTGGATGCGCCGCGCGGGGAGGGGGGCTTCGGCTACGATCCGCTCTTTCTG
GTTCCCGAGCACGGGCAGACCTTCTCCGAACTTCCGATGGAGATCAAAAACACCATCAGCCACCGCGGCCGCGCCATGCA
GATGCTCAAAGAGGCGCTGCAAAAACGGGAAGACGTCTCACGCTAA

Upstream 100 bases:

>100_bases
AGGCGGAGCCTTTCACCCTCGACCAGATGGACGCCATGCGCAGGCACGCGATGCTCGGCCTCTCCCGCCTCTTCGAGATC
CAGCAGGAGGCTTTGCAGGC

Downstream 100 bases:

>100_bases
GACGCAAAGACGCAAAGAAAAGCAAGACAGCAAAAAAGACTCTCTAACAGGGATAAAGGGGATGCAGGGGATGCAGGGGA
TTAGGCATAAGCTTTGTTCT

Product: nucleoside-triphosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MKELLVASGNKGKLREFEKLLEGVVETILSPADFPGLPEVEEDGDSFEANALKKARSAALFTGKPVLSDDSGLCVDHLGG
RPGVYSARFAGEGAGDAANNARLLQEMAGVPREERTGAFHCVIALCLPDGSCQTFDGMLKGEILDAPRGEGGFGYDPLFL
VPEHGQTFSELPMEIKNTISHRGRAMQMLKEALQKREDVSR

Sequences:

>Translated_201_residues
MKELLVASGNKGKLREFEKLLEGVVETILSPADFPGLPEVEEDGDSFEANALKKARSAALFTGKPVLSDDSGLCVDHLGG
RPGVYSARFAGEGAGDAANNARLLQEMAGVPREERTGAFHCVIALCLPDGSCQTFDGMLKGEILDAPRGEGGFGYDPLFL
VPEHGQTFSELPMEIKNTISHRGRAMQMLKEALQKREDVSR
>Mature_201_residues
MKELLVASGNKGKLREFEKLLEGVVETILSPADFPGLPEVEEDGDSFEANALKKARSAALFTGKPVLSDDSGLCVDHLGG
RPGVYSARFAGEGAGDAANNARLLQEMAGVPREERTGAFHCVIALCLPDGSCQTFDGMLKGEILDAPRGEGGFGYDPLFL
VPEHGQTFSELPMEIKNTISHRGRAMQMLKEALQKREDVSR

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=192, Percent_Identity=32.8125, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI31657144, Length=157, Percent_Identity=34.3949044585987, Blast_Score=74, Evalue=7e-14,
Organism=Escherichia coli, GI1789324, Length=197, Percent_Identity=44.6700507614213, Blast_Score=162, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17556833, Length=199, Percent_Identity=30.6532663316583, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6322529, Length=202, Percent_Identity=30.6930693069307, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19920712, Length=200, Percent_Identity=33, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21635; Mature: 21635

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELLVASGNKGKLREFEKLLEGVVETILSPADFPGLPEVEEDGDSFEANALKKARSAAL
CCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
FTGKPVLSDDSGLCVDHLGGRPGVYSARFAGEGAGDAANNARLLQEMAGVPREERTGAFH
CCCCCCCCCCCCCCHHHCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCHHCCCEE
CVIALCLPDGSCQTFDGMLKGEILDAPRGEGGFGYDPLFLVPEHGQTFSELPMEIKNTIS
EEEEEECCCCCCHHHHHHHHCHHCCCCCCCCCCCCCCEEEECCCCCCHHHCCHHHHHHHH
HRGRAMQMLKEALQKREDVSR
HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKELLVASGNKGKLREFEKLLEGVVETILSPADFPGLPEVEEDGDSFEANALKKARSAAL
CCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
FTGKPVLSDDSGLCVDHLGGRPGVYSARFAGEGAGDAANNARLLQEMAGVPREERTGAFH
CCCCCCCCCCCCCCHHHCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCHHCCCEE
CVIALCLPDGSCQTFDGMLKGEILDAPRGEGGFGYDPLFLVPEHGQTFSELPMEIKNTIS
EEEEEECCCCCCHHHHHHHHCHHCCCCCCCCCCCCCCEEEECCCCCCHHHCCHHHHHHHH
HRGRAMQMLKEALQKREDVSR
HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA