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The map label for this gene is czcR [H]

Identifier: 197116707

GI number: 197116707

Start: 380468

End: 381349

Strand: Direct

Name: czcR [H]

Synonym: Gbem_0307

Alternate gene names: 197116707

Gene position: 380468-381349 (Clockwise)

Preceding gene: 197116706

Following gene: 197116708

Centisome position: 8.24

GC content: 59.75

Gene sequence:

>882_bases
GTGTCTCTACGCAGCCTTCGCATCCTCACCGCCATTGCCGGCAAAGGCACCTTTGCAGCCGCCGCCGACCAATTGGGGCT
AACCCAGTCGGCTATAAGCCTGCAGGTAAAGAAGTTAGAGGACGAATTCGGCGTGCAGCTTTTCGAGAGGACCGGCCGTA
GTCCCAAGCTCAACATGAATGGCCGTTACGTTGTAGAACGGGCTTCCGAGATCCTTCTTATCTACGATGAAATGAAAGCC
CGCCTATCCCCGCTTGGCGGCGTGCAGGGGCTGCTGACGCTGGGGGCGGTCCCTACCGTGATCACGGGCTCGCTTCCCCC
CGCACTCGGGCGGCTGCGAACCCGCTACCAGGACATGCAAGTCAAACTCGTTTCCGGCCTCTCCACCGAATTGGTCCGCA
AAGTCGAGGAGGGTGACCTGGACGCCGCCTTGACTACAGAGCCCCCCTACGCCGTGCCGCCGCAATACGAATGGATTCCC
TATGATGAAGAACCCTTCTTCGTGGTTGCACCCAAGGAGGCCGGCATCAACGATGTCGCGCTGCTGTTCGAGCGCTTCCC
TTTCGTGCGTTTCGACAAGATGGCCTGGGCAGGCGCCATGGTAGATCATGAGCTGATGCTGCAAGGGATCCGTCCGCGCG
AGGTTATGGAATTCGATTCGTTGGAAATGGCCCTCGCCCTGGTGGAAGAAGGTCTGGGGATAGCTGTGGTGCCGCTGAGC
AAATCGCGCCTGGAGCAGGTCGCGAACCATTTCACCCTCACCCCTTTCGGCACCCCACAGTTAAGCCGGCGCGTGGGGAT
GTACCAGAAGCGGCAACATCCGCGCCAGCCATTGACCCGTGCGGTTCTGGACGAGTTGTCGCAGCAAGTAAACCTCAAGT
AA

Upstream 100 bases:

>100_bases
GGAATTCGGCCTGCGCAATCTCGATCTAGCCGCTTTGCAGAGCCGGCTTTCTTACCTCTTTGCCTGAGGGGAGAGATAGA
CCCCCGTAAAGGAGAGTATC

Downstream 100 bases:

>100_bases
AACTCAAGGCTCCCGTAAAAACTATCAACTTTTTCTCAAGACAATGTCATGCTACCCTCTTTCTACAGTCCAACATGAAG
AGGTTCGAGTATGACCGTTA

Product: solute-binding transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSLRSLRILTAIAGKGTFAAAADQLGLTQSAISLQVKKLEDEFGVQLFERTGRSPKLNMNGRYVVERASEILLIYDEMKA
RLSPLGGVQGLLTLGAVPTVITGSLPPALGRLRTRYQDMQVKLVSGLSTELVRKVEEGDLDAALTTEPPYAVPPQYEWIP
YDEEPFFVVAPKEAGINDVALLFERFPFVRFDKMAWAGAMVDHELMLQGIRPREVMEFDSLEMALALVEEGLGIAVVPLS
KSRLEQVANHFTLTPFGTPQLSRRVGMYQKRQHPRQPLTRAVLDELSQQVNLK

Sequences:

>Translated_293_residues
MSLRSLRILTAIAGKGTFAAAADQLGLTQSAISLQVKKLEDEFGVQLFERTGRSPKLNMNGRYVVERASEILLIYDEMKA
RLSPLGGVQGLLTLGAVPTVITGSLPPALGRLRTRYQDMQVKLVSGLSTELVRKVEEGDLDAALTTEPPYAVPPQYEWIP
YDEEPFFVVAPKEAGINDVALLFERFPFVRFDKMAWAGAMVDHELMLQGIRPREVMEFDSLEMALALVEEGLGIAVVPLS
KSRLEQVANHFTLTPFGTPQLSRRVGMYQKRQHPRQPLTRAVLDELSQQVNLK
>Mature_292_residues
SLRSLRILTAIAGKGTFAAAADQLGLTQSAISLQVKKLEDEFGVQLFERTGRSPKLNMNGRYVVERASEILLIYDEMKAR
LSPLGGVQGLLTLGAVPTVITGSLPPALGRLRTRYQDMQVKLVSGLSTELVRKVEEGDLDAALTTEPPYAVPPQYEWIPY
DEEPFFVVAPKEAGINDVALLFERFPFVRFDKMAWAGAMVDHELMLQGIRPREVMEFDSLEMALALVEEGLGIAVVPLSK
SRLEQVANHFTLTPFGTPQLSRRVGMYQKRQHPRQPLTRAVLDELSQQVNLK

Specific function: Transcriptional Activator Of The Hca Operon For 3- Phenylpropionic Acid Catabolism. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788887, Length=245, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI145693105, Length=241, Percent_Identity=23.6514522821577, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787806, Length=250, Percent_Identity=26.4, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI2367136, Length=256, Percent_Identity=25.78125, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788748, Length=247, Percent_Identity=25.9109311740891, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787879, Length=288, Percent_Identity=25.6944444444444, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790399, Length=145, Percent_Identity=31.7241379310345, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788481, Length=289, Percent_Identity=24.9134948096886, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789492, Length=142, Percent_Identity=31.6901408450704, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787530, Length=310, Percent_Identity=24.8387096774194, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI157672245, Length=234, Percent_Identity=24.3589743589744, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788626, Length=151, Percent_Identity=33.112582781457, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI87082132, Length=152, Percent_Identity=28.2894736842105, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082024, Length=245, Percent_Identity=26.1224489795918, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786401, Length=143, Percent_Identity=34.2657342657343, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32591; Mature: 32460

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRSLRILTAIAGKGTFAAAADQLGLTQSAISLQVKKLEDEFGVQLFERTGRSPKLNMN
CCCCHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCC
GRYVVERASEILLIYDEMKARLSPLGGVQGLLTLGAVPTVITGSLPPALGRLRTRYQDMQ
CCEEEECCCCEEEEHHHHHHHHCCCCCHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHH
VKLVSGLSTELVRKVEEGDLDAALTTEPPYAVPPQYEWIPYDEEPFFVVAPKEAGINDVA
HHHHHCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHH
LLFERFPFVRFDKMAWAGAMVDHELMLQGIRPREVMEFDSLEMALALVEEGLGIAVVPLS
HHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECC
KSRLEQVANHFTLTPFGTPQLSRRVGMYQKRQHPRQPLTRAVLDELSQQVNLK
HHHHHHHHHCEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLRSLRILTAIAGKGTFAAAADQLGLTQSAISLQVKKLEDEFGVQLFERTGRSPKLNMN
CCCHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCC
GRYVVERASEILLIYDEMKARLSPLGGVQGLLTLGAVPTVITGSLPPALGRLRTRYQDMQ
CCEEEECCCCEEEEHHHHHHHHCCCCCHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHH
VKLVSGLSTELVRKVEEGDLDAALTTEPPYAVPPQYEWIPYDEEPFFVVAPKEAGINDVA
HHHHHCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHH
LLFERFPFVRFDKMAWAGAMVDHELMLQGIRPREVMEFDSLEMALALVEEGLGIAVVPLS
HHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECC
KSRLEQVANHFTLTPFGTPQLSRRVGMYQKRQHPRQPLTRAVLDELSQQVNLK
HHHHHHHHHCEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9099864; 9308178; 9384377 [H]