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The map label for this gene is pdxA [H]

Identifier: 197116478

GI number: 197116478

Start: 93585

End: 94586

Strand: Direct

Name: pdxA [H]

Synonym: Gbem_0078

Alternate gene names: 197116478

Gene position: 93585-94586 (Clockwise)

Preceding gene: 197116477

Following gene: 197116479

Centisome position: 2.03

GC content: 66.57

Gene sequence:

>1002_bases
TTGGATAAACCAGTAATAGCCGTCACCATGGGGGATCCCTGCGGCATAGGGCCGGAGATCATCGCGGCGGCGCTCGCCGA
CCCGGCCATCACGGCGCTTTGTCGTCCGCTGGTCCTCGGGGACCGGGGCGCCATGGAGCGCGGCATAGCGGTGGCTGGGG
TCAAGCTCGCCATAGCGTCCGCGCCCGACCTGCTACCCCCCCTCGACGCGTCCCCCCATACCCTTTACCTGCGCGAGCTG
TCACGGCTGAAGCTCGACGAGATCCCTTACGGCGCCCCGACCAAGGCCGGAGGGGACGCCTGCTACCGCTACATCTGCGA
AGCGGCCAAGCTCTGCCTGGACGGGACGGTGCAGGCCATGGCCACCGCCCCCATCAATAAGGAATCGATGAACAGCGCCG
GGCACGACTACCCGGGCCACACGGAGCTTCTAGCGGAATTGACCGGGACCCCGGAGGTGGTGATGATGCTCGCCGGCGAG
CGCCTGCGGGTGACGCTCGTGACCATCCACGAGCCGCTTGCCAGGGTGCCGGAACTGGTCACCTTCGACCGCGTTCTCTC
CACCATCAGGATCACTCACGACGCCCTCAGCCGCTGGTTCTGCTGTGCGCCGCGCCTGGCCGTCCTCGCCCTCAACCCGC
ACTGCGGCGAGGGGGGGATGTTCGGCGACGAGGAGTCCCGGATCATCGCGCCTGCGGTCGCTGCCGCGAGGGAAGCAGGT
ATTGACGCTGCAGGCCCCGTTTCCGCAGACACCCTGTTCCACTTCGCCGCCAAAGGTGGGTACGACGCGGTGGTCTGCAT
GTACCACGACCAGGGGTTGATCCCCTTGAAGCTTTTGCATTTCGACGACGGGGTCAACGTGACCCTGGGGCTTCCCATCA
TCCGCACCTCGGTCGATCACGGCACCGCCTACAACCTGGCGGGGACGGGGAAAGCGAGCGCGGAAAGCATGAAAGCCGCG
CTGGTCATGGCGGCACGCATGGCACAGCAGGGTTGCCAATAG

Upstream 100 bases:

>100_bases
GTTCGGCGCTGCCTTCAAAACCTCCCTCACCCCAACCCTCTCCCAGAGGCAGAGGGAGCCTGGACGGAAACTCCGAAGAA
AGTGTGGATAGGAGAGCATC

Downstream 100 bases:

>100_bases
CTATCAAAAGAGGCGGGATTATCTGATGAAAAAGTATCTTACCTGGGGCGGGATCGTCCTTGCCGTTTACCTCATCTACG
TGGTGATCTCCCTGGCCATG

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MDKPVIAVTMGDPCGIGPEIIAAALADPAITALCRPLVLGDRGAMERGIAVAGVKLAIASAPDLLPPLDASPHTLYLREL
SRLKLDEIPYGAPTKAGGDACYRYICEAAKLCLDGTVQAMATAPINKESMNSAGHDYPGHTELLAELTGTPEVVMMLAGE
RLRVTLVTIHEPLARVPELVTFDRVLSTIRITHDALSRWFCCAPRLAVLALNPHCGEGGMFGDEESRIIAPAVAAAREAG
IDAAGPVSADTLFHFAAKGGYDAVVCMYHDQGLIPLKLLHFDDGVNVTLGLPIIRTSVDHGTAYNLAGTGKASAESMKAA
LVMAARMAQQGCQ

Sequences:

>Translated_333_residues
MDKPVIAVTMGDPCGIGPEIIAAALADPAITALCRPLVLGDRGAMERGIAVAGVKLAIASAPDLLPPLDASPHTLYLREL
SRLKLDEIPYGAPTKAGGDACYRYICEAAKLCLDGTVQAMATAPINKESMNSAGHDYPGHTELLAELTGTPEVVMMLAGE
RLRVTLVTIHEPLARVPELVTFDRVLSTIRITHDALSRWFCCAPRLAVLALNPHCGEGGMFGDEESRIIAPAVAAAREAG
IDAAGPVSADTLFHFAAKGGYDAVVCMYHDQGLIPLKLLHFDDGVNVTLGLPIIRTSVDHGTAYNLAGTGKASAESMKAA
LVMAARMAQQGCQ
>Mature_333_residues
MDKPVIAVTMGDPCGIGPEIIAAALADPAITALCRPLVLGDRGAMERGIAVAGVKLAIASAPDLLPPLDASPHTLYLREL
SRLKLDEIPYGAPTKAGGDACYRYICEAAKLCLDGTVQAMATAPINKESMNSAGHDYPGHTELLAELTGTPEVVMMLAGE
RLRVTLVTIHEPLARVPELVTFDRVLSTIRITHDALSRWFCCAPRLAVLALNPHCGEGGMFGDEESRIIAPAVAAAREAG
IDAAGPVSADTLFHFAAKGGYDAVVCMYHDQGLIPLKLLHFDDGVNVTLGLPIIRTSVDHGTAYNLAGTGKASAESMKAA
LVMAARMAQQGCQ

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=331, Percent_Identity=39.2749244712991, Blast_Score=187, Evalue=6e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 34972; Mature: 34972

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKPVIAVTMGDPCGIGPEIIAAALADPAITALCRPLVLGDRGAMERGIAVAGVKLAIAS
CCCCEEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCHHHCCEEEECEEEEEEC
APDLLPPLDASPHTLYLRELSRLKLDEIPYGAPTKAGGDACYRYICEAAKLCLDGTVQAM
CCCCCCCCCCCCCCHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHH
ATAPINKESMNSAGHDYPGHTELLAELTGTPEVVMMLAGERLRVTLVTIHEPLARVPELV
EECCCCHHHHCCCCCCCCCHHHHHHHHCCCHHEEEEECCCCEEEEEEEEHHHHHHHHHHH
TFDRVLSTIRITHDALSRWFCCAPRLAVLALNPHCGEGGMFGDEESRIIAPAVAAAREAG
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCEEHHHHHHHHHCC
IDAAGPVSADTLFHFAAKGGYDAVVCMYHDQGLIPLKLLHFDDGVNVTLGLPIIRTSVDH
CCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEECCCCEEEECCCEEEEECCC
GTAYNLAGTGKASAESMKAALVMAARMAQQGCQ
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDKPVIAVTMGDPCGIGPEIIAAALADPAITALCRPLVLGDRGAMERGIAVAGVKLAIAS
CCCCEEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCHHHCCEEEECEEEEEEC
APDLLPPLDASPHTLYLRELSRLKLDEIPYGAPTKAGGDACYRYICEAAKLCLDGTVQAM
CCCCCCCCCCCCCCHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHH
ATAPINKESMNSAGHDYPGHTELLAELTGTPEVVMMLAGERLRVTLVTIHEPLARVPELV
EECCCCHHHHCCCCCCCCCHHHHHHHHCCCHHEEEEECCCCEEEEEEEEHHHHHHHHHHH
TFDRVLSTIRITHDALSRWFCCAPRLAVLALNPHCGEGGMFGDEESRIIAPAVAAAREAG
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCEEHHHHHHHHHCC
IDAAGPVSADTLFHFAAKGGYDAVVCMYHDQGLIPLKLLHFDDGVNVTLGLPIIRTSVDH
CCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEECCCCEEEECCCEEEEECCC
GTAYNLAGTGKASAESMKAALVMAARMAQQGCQ
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA