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The map label for this gene is mtgA [H]

Identifier: 197116479

GI number: 197116479

Start: 94612

End: 95571

Strand: Direct

Name: mtgA [H]

Synonym: Gbem_0079

Alternate gene names: 197116479

Gene position: 94612-95571 (Clockwise)

Preceding gene: 197116478

Following gene: 197116480

Centisome position: 2.05

GC content: 62.81

Gene sequence:

>960_bases
ATGAAAAAGTATCTTACCTGGGGCGGGATCGTCCTTGCCGTTTACCTCATCTACGTGGTGATCTCCCTGGCCATGACGCC
GCCGGTGACGGAGCTCAAAGACAAGAAGTTCAACATGACCATCCAGGTGAAGGACTGGCAGGGGAACTACCACCCGCTGG
TGGTGGGCCCGAAGAACCGTTACTGGACCCCGCTGTCGCAGATCCCCTCCGAGATGAAATGGGCGGTCATCCTCGCCGAG
GACGCATCCTTCTACAAGCACGAGGGGATCGACGTCAAGGCGATCAAGGAAGCGATCAAGTACGACCTGGAGAAGCAGAG
TTTCGCCCGCGGCGCCTCGACCATCACCCAGCAGGTGGCCAAGAACCTGTTCCTGTCCCGCGAGAAGACCCTGACCAGGA
AGGCCAAGGAGCTCTACCTGGCGAAGAGGATGGAGCAGGAGCTGACCAAGGGGAGGATCATCGAGCTTTATCTGAACGTG
ATCGAGCTGGGCCCACTGGTGCACGGCATCGGTCACGGCGCGCGCTACTACTTCGGCAAGTCCCCGGCCAACCTCACCCC
GCGCGAATGCGCCTTTCTGGCCGCCATGCTCCCGGGCCCCCGGGTCGCCTACAACCCGTACAAGAACCTGGGCAAGGTGC
TGAAGCGCTCAAACATGATCCTGGGGCTTCTCGCCAAAAAGGGGGTTCTGAGCGAAGCGGAATATCGCACCGCGCTGGCG
CAGTCGCCGAACGTCGGACGGATGCAGCGTAAGGTCGATATGAGCATCAAGCAGGTCGAGGTGATGGCGAACCACACTTC
GGCTACCCTCCCGGAGCAGCCCCTGTCGCAGGAGGAGATGAACGCGCAGGAGCCGAAAGCCGGCGCGCCGGAGGGAGCCG
CGCCTCAGCCCGCTCCGGAGCCGGCGCAGGAGCCCGCGTCGCCTGCCTCCCCCCCCGCGGCGCAGGAAGAAAAGCAGTAA

Upstream 100 bases:

>100_bases
GGGAAAGCGAGCGCGGAAAGCATGAAAGCCGCGCTGGTCATGGCGGCACGCATGGCACAGCAGGGTTGCCAATAGCTATC
AAAAGAGGCGGGATTATCTG

Downstream 100 bases:

>100_bases
CGGTCGCATGGCAGGAGCAAATCCCTCCTGTCCCCCCCTCCCTTGACGGGAGGGGGACGGGGGGCGGGTGAAGCTGCAAA
GTACGGAAATGATGGCACCT

Product: biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MKKYLTWGGIVLAVYLIYVVISLAMTPPVTELKDKKFNMTIQVKDWQGNYHPLVVGPKNRYWTPLSQIPSEMKWAVILAE
DASFYKHEGIDVKAIKEAIKYDLEKQSFARGASTITQQVAKNLFLSREKTLTRKAKELYLAKRMEQELTKGRIIELYLNV
IELGPLVHGIGHGARYYFGKSPANLTPRECAFLAAMLPGPRVAYNPYKNLGKVLKRSNMILGLLAKKGVLSEAEYRTALA
QSPNVGRMQRKVDMSIKQVEVMANHTSATLPEQPLSQEEMNAQEPKAGAPEGAAPQPAPEPAQEPASPASPPAAQEEKQ

Sequences:

>Translated_319_residues
MKKYLTWGGIVLAVYLIYVVISLAMTPPVTELKDKKFNMTIQVKDWQGNYHPLVVGPKNRYWTPLSQIPSEMKWAVILAE
DASFYKHEGIDVKAIKEAIKYDLEKQSFARGASTITQQVAKNLFLSREKTLTRKAKELYLAKRMEQELTKGRIIELYLNV
IELGPLVHGIGHGARYYFGKSPANLTPRECAFLAAMLPGPRVAYNPYKNLGKVLKRSNMILGLLAKKGVLSEAEYRTALA
QSPNVGRMQRKVDMSIKQVEVMANHTSATLPEQPLSQEEMNAQEPKAGAPEGAAPQPAPEPAQEPASPASPPAAQEEKQ
>Mature_319_residues
MKKYLTWGGIVLAVYLIYVVISLAMTPPVTELKDKKFNMTIQVKDWQGNYHPLVVGPKNRYWTPLSQIPSEMKWAVILAE
DASFYKHEGIDVKAIKEAIKYDLEKQSFARGASTITQQVAKNLFLSREKTLTRKAKELYLAKRMEQELTKGRIIELYLNV
IELGPLVHGIGHGARYYFGKSPANLTPRECAFLAAMLPGPRVAYNPYKNLGKVLKRSNMILGLLAKKGVLSEAEYRTALA
QSPNVGRMQRKVDMSIKQVEVMANHTSATLPEQPLSQEEMNAQEPKAGAPEGAAPQPAPEPAQEPASPASPPAAQEEKQ

Specific function: Cell wall formation [H]

COG id: COG5009

COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family [H]

Homologues:

Organism=Escherichia coli, GI87082258, Length=234, Percent_Identity=38.034188034188, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1786343, Length=165, Percent_Identity=36.969696969697, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789601, Length=160, Percent_Identity=40.625, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788867, Length=162, Percent_Identity=35.1851851851852, Blast_Score=85, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001264
- InterPro:   IPR011812 [H]

Pfam domain/function: PF00912 Transgly [H]

EC number: 2.4.2.-; 3.4.-.- [C]

Molecular weight: Translated: 35486; Mature: 35486

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYLTWGGIVLAVYLIYVVISLAMTPPVTELKDKKFNMTIQVKDWQGNYHPLVVGPKNR
CCCEECHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEEEEEECCCCCEEEEECCCCC
YWTPLSQIPSEMKWAVILAEDASFYKHEGIDVKAIKEAIKYDLEKQSFARGASTITQQVA
CCCCHHHCCCCCEEEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNLFLSREKTLTRKAKELYLAKRMEQELTKGRIIELYLNVIELGPLVHGIGHGARYYFGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCEEEECC
SPANLTPRECAFLAAMLPGPRVAYNPYKNLGKVLKRSNMILGLLAKKGVLSEAEYRTALA
CCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHEEHHHHCCCCHHHHHHHHHH
QSPNVGRMQRKVDMSIKQVEVMANHTSATLPEQPLSQEEMNAQEPKAGAPEGAAPQPAPE
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCC
PAQEPASPASPPAAQEEKQ
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKYLTWGGIVLAVYLIYVVISLAMTPPVTELKDKKFNMTIQVKDWQGNYHPLVVGPKNR
CCCEECHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEEEEEECCCCCEEEEECCCCC
YWTPLSQIPSEMKWAVILAEDASFYKHEGIDVKAIKEAIKYDLEKQSFARGASTITQQVA
CCCCHHHCCCCCEEEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNLFLSREKTLTRKAKELYLAKRMEQELTKGRIIELYLNVIELGPLVHGIGHGARYYFGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCEEEECC
SPANLTPRECAFLAAMLPGPRVAYNPYKNLGKVLKRSNMILGLLAKKGVLSEAEYRTALA
CCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHEEHHHHCCCCHHHHHHHHHH
QSPNVGRMQRKVDMSIKQVEVMANHTSATLPEQPLSQEEMNAQEPKAGAPEGAAPQPAPE
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCC
PAQEPASPASPPAAQEEKQ
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]