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The map label for this gene is hypA-2 [H]

Identifier: 197116470

GI number: 197116470

Start: 85302

End: 85676

Strand: Direct

Name: hypA-2 [H]

Synonym: Gbem_0070

Alternate gene names: 197116470

Gene position: 85302-85676 (Clockwise)

Preceding gene: 197116469

Following gene: 197116471

Centisome position: 1.85

GC content: 62.93

Gene sequence:

>375_bases
ATGCACGAAATCACCCTGGTCACCGGACTCTTCGAGATCATCAACCGCGAGGTCGCCGCGCGCGGCATCGAATCCATCTC
CAAGGTGCGCCTGATGGTGGGGGAACTGGCGGCGGTGGAACCGATGACGCTTGCCGCCTGCTTCGAGGTGGTGGCGGAGG
GGACGGTGGCTTCCGGGGCGCAACTGGAAATCGAGACGGTCCATTTGACCGGCCGCTGCCGCGGCTGCGCCAGCGGCTTT
CGCATCGTCGGCTTTCGGTTCCAGTGTCCCGACTGCGGAGGAGGGGACGTCGAGCTGTCGGGTGGGAGGGAACTTTATTT
GGAGAGCTTGGAGGCCATATGCAAAGGAGACCACAATGAAGCAACAGCAGCGTGA

Upstream 100 bases:

>100_bases
CGCTCAAGGTGATGCTCCACGGCGAGCCGGTGGCGAACATCCCGCTCATCGTGAACAGCATCGACCCCTGCATCGCCTGC
ACGGACCGCTAGGAGGAGCC

Downstream 100 bases:

>100_bases
GAATGCCATAGTCTTTGCCGATCCCGAGCGCTGTCTCGGCTGCCACGGCTGCGAGCTGGCCTGCGCCCTGGCCCATTCCG
GAACCGGGCTGCACCAGGCG

Product: hydrogenase nickel insertion protein HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 124; Mature: 124

Protein sequence:

>124_residues
MHEITLVTGLFEIINREVAARGIESISKVRLMVGELAAVEPMTLAACFEVVAEGTVASGAQLEIETVHLTGRCRGCASGF
RIVGFRFQCPDCGGGDVELSGGRELYLESLEAICKGDHNEATAA

Sequences:

>Translated_124_residues
MHEITLVTGLFEIINREVAARGIESISKVRLMVGELAAVEPMTLAACFEVVAEGTVASGAQLEIETVHLTGRCRGCASGF
RIVGFRFQCPDCGGGDVELSGGRELYLESLEAICKGDHNEATAA
>Mature_124_residues
MHEITLVTGLFEIINREVAARGIESISKVRLMVGELAAVEPMTLAACFEVVAEGTVASGAQLEIETVHLTGRCRGCASGF
RIVGFRFQCPDCGGGDVELSGGRELYLESLEAICKGDHNEATAA

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step [H]

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family [H]

Homologues:

Organism=Escherichia coli, GI1789365, Length=111, Percent_Identity=32.4324324324324, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI1789081, Length=112, Percent_Identity=31.25, Blast_Score=63, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000688
- InterPro:   IPR020538 [H]

Pfam domain/function: PF01155 HypA [H]

EC number: NA

Molecular weight: Translated: 13129; Mature: 13129

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEITLVTGLFEIINREVAARGIESISKVRLMVGELAAVEPMTLAACFEVVAEGTVASGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
QLEIETVHLTGRCRGCASGFRIVGFRFQCPDCGGGDVELSGGRELYLESLEAICKGDHNE
EEEEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCEEEECCCHHHHHHHHHHHHCCCCCC
ATAA
CCCC
>Mature Secondary Structure
MHEITLVTGLFEIINREVAARGIESISKVRLMVGELAAVEPMTLAACFEVVAEGTVASGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
QLEIETVHLTGRCRGCASGFRIVGFRFQCPDCGGGDVELSGGRELYLESLEAICKGDHNE
EEEEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCEEEECCCHHHHHHHHHHHHCCCCCC
ATAA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA