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The map label for this gene is crp [C]

Identifier: 197116466

GI number: 197116466

Start: 81597

End: 82259

Strand: Direct

Name: crp [C]

Synonym: Gbem_0066

Alternate gene names: 197116466

Gene position: 81597-82259 (Clockwise)

Preceding gene: 197116457

Following gene: 197116467

Centisome position: 1.77

GC content: 61.54

Gene sequence:

>663_bases
ATGCCGAACAAGATGAAGCTCACTGCCGCGGACCTCTTATCGCTTTTTAACCCCGCTGACTCCGATCAGTTCCTCGCCCA
TTTCACCACCCGCCACTACCCCCCGAAGGCACTGGTCTATTCTCCGTTCGAGGAGAAGAACCTGGTGTTCGTGGTGAAAA
GCGGCCGGCTTCGGGTCTACCTCGCTTACGAGGACAAGGAGTTCACCCTGGCGCTCCTGGAGCCGGGGGATGTCTTCAGT
ACCCATACGCCCGCTTTCGTGCAGGCGCTGGAAGGAAGCGAGATCCTCGTCTGCAGTACGGCAACGTTCCGGGAGGCGGT
GGCGCGGCGGCCGGAACTCTCGCTCACTATGGTAAAGGTGCTGGGAGAGCTCCTGAAGAACTCGATAGAGACCATCGAGG
GGCTCGCCTTCAAGGACGTCCGCCTGCGCCTGGTGGATTTCCTGCTGGGTGCCGCCGCCGAGCGCGGCCGGGCGAGCACC
GAAGGGACGGTGGTGCAACTGGGCCTCGGCACCGAGGACATCGCCCTGCTCATCGGCACCACGCGCCAGACCATCTCCCA
GATCGTCAACGACTTCATAAAGGCCGACCTGCTGCGTAAGATCGACCGCAAGACCCTCCTTATCACCGACATGGACGCAC
TCAAGGCGCTTAGGGAACTGTAA

Upstream 100 bases:

>100_bases
AGTGGAGATGAAACAGACGCGACCGCGTTTCTCATCTTGCAGGGAGCAGCGGCGTTGCCTATGATGCAATCAATGATCGC
TTGATGAAAGGTGCAACCCG

Downstream 100 bases:

>100_bases
ATCCTCATCGCTCCCCAGGCAGTTTCGGTTAGGCATTTGCACTATCTTCATCGAGCAGTTTCCAGCTCCCCCTCCCTTGA
CGGGAGGGGGCAGGGGGGTG

Product: cyclic nucleotide-binding transcriptional activator

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Transcriptional Regulator; Crp-Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Carbon Monoxide Dehydrogenase CooA Protein; Transcriptional Regulator MrpC

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MPNKMKLTAADLLSLFNPADSDQFLAHFTTRHYPPKALVYSPFEEKNLVFVVKSGRLRVYLAYEDKEFTLALLEPGDVFS
THTPAFVQALEGSEILVCSTATFREAVARRPELSLTMVKVLGELLKNSIETIEGLAFKDVRLRLVDFLLGAAAERGRAST
EGTVVQLGLGTEDIALLIGTTRQTISQIVNDFIKADLLRKIDRKTLLITDMDALKALREL

Sequences:

>Translated_220_residues
MPNKMKLTAADLLSLFNPADSDQFLAHFTTRHYPPKALVYSPFEEKNLVFVVKSGRLRVYLAYEDKEFTLALLEPGDVFS
THTPAFVQALEGSEILVCSTATFREAVARRPELSLTMVKVLGELLKNSIETIEGLAFKDVRLRLVDFLLGAAAERGRAST
EGTVVQLGLGTEDIALLIGTTRQTISQIVNDFIKADLLRKIDRKTLLITDMDALKALREL
>Mature_219_residues
PNKMKLTAADLLSLFNPADSDQFLAHFTTRHYPPKALVYSPFEEKNLVFVVKSGRLRVYLAYEDKEFTLALLEPGDVFST
HTPAFVQALEGSEILVCSTATFREAVARRPELSLTMVKVLGELLKNSIETIEGLAFKDVRLRLVDFLLGAAAERGRASTE
GTVVQLGLGTEDIALLIGTTRQTISQIVNDFIKADLLRKIDRKTLLITDMDALKALREL

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 24456; Mature: 24325

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNKMKLTAADLLSLFNPADSDQFLAHFTTRHYPPKALVYSPFEEKNLVFVVKSGRLRVY
CCCCEEECHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCEEEEEECCCEEEE
LAYEDKEFTLALLEPGDVFSTHTPAFVQALEGSEILVCSTATFREAVARRPELSLTMVKV
EEEECCCEEEEEECCCCCCCCCCHHHHHHCCCCEEEEECCHHHHHHHHCCCCCHHHHHHH
LGELLKNSIETIEGLAFKDVRLRLVDFLLGAAAERGRASTEGTVVQLGLGTEDIALLIGT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEEC
TRQTISQIVNDFIKADLLRKIDRKTLLITDMDALKALREL
CHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHCC
>Mature Secondary Structure 
PNKMKLTAADLLSLFNPADSDQFLAHFTTRHYPPKALVYSPFEEKNLVFVVKSGRLRVY
CCCEEECHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCEEEEEECCCEEEE
LAYEDKEFTLALLEPGDVFSTHTPAFVQALEGSEILVCSTATFREAVARRPELSLTMVKV
EEEECCCEEEEEECCCCCCCCCCHHHHHHCCCCEEEEECCHHHHHHHHCCCCCHHHHHHH
LGELLKNSIETIEGLAFKDVRLRLVDFLLGAAAERGRASTEGTVVQLGLGTEDIALLIGT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEEC
TRQTISQIVNDFIKADLLRKIDRKTLLITDMDALKALREL
CHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA