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The map label for this gene is mcp040 [H]

Identifier: 197116440

GI number: 197116440

Start: 49794

End: 51341

Strand: Reverse

Name: mcp040 [H]

Synonym: Gbem_0040

Alternate gene names: 197116440

Gene position: 51341-49794 (Counterclockwise)

Preceding gene: 197116441

Following gene: 197116439

Centisome position: 1.11

GC content: 63.89

Gene sequence:

>1548_bases
ATGTCCTTATTCTCTCGCGTCTTAACGATCAACTTCATTGCTGTCGCAGCCACGATTGGCGCTGCCGTTGCCTTCGGCAG
CGGGGTTGGTCTGTTCGCCGTCGGCGCCGTGATAATCCTCCTATGCGCCGTAGCCTGCGGCCTGTCGTCACGTGGGGAAA
CCAAGGCGCTGGAGGAAATGGCCATCGCGCTGGAAAGCGCCGCGGCGGGCAACCTTTCCTACCGGGTGACCGCCGCCGGC
AACGGCGAGATAGGACGCATAGGGTCCGCATTCAACACCATGATGGGCGACTGGAACAAGACCATGCACCAGTTCTTCAC
CGTCACCGATCTGGTACGCGATTCCGTCGCCCTGGTGAGCGCGACGAACGACGCCATGGCTGCCGCGGCCGAGGACGTCG
CGCTGCAGGCCTCCACCATAGCTACCGCCAGTGAAGAAATGTCCGCCACCTCCGGCGACATTGCGCGCAACTGCCTCTAC
GCCGCCGAGAACGCCCACAGGGCCACCGAGGAGACCACCTCCGGCGCCGAGATCGTCAGCAACAGCGCAAGGCTCATGGA
GAACATCGCCCAGCGCGTCATGGCCACCTCCAGTTCCGTCGCAGGGTTGGGCGAGCGTTCCGACCAGATCGGCGCCATAG
CCGGGACCATCGAGGACATCGCCGACCAGACGAACCTTTTGGCCCTGAACGCGGCCATCGAGGCCGCCCGCGCCGGCGAG
ACCGGCCGCGGCTTCGCCGTCGTCGCCGACGAAGTGCGCGCCCTGGCGGAGCGGACCACCCGCGCCACCAAGGAGATCGA
CGCCATGATCAAGTCGATCCAGACCGAGACCAGAGCCGCCGTCGGCTCCATGGGAGAAGGGGTCGAGCAGGTGAACCAGG
GAACCGCCGAAACCTGCCGCTCCGGCGAGGCGCTGAACGGCATCCTCAAGATGATCAACGACCTGACCATGCAGCTCTCC
CAGATCGCCACCGCGGCGGAGGAGCAGACGGCTACCACCCACGAGATCACCAGCAACATCCAGATGATTACCAGCGTGGT
CAACAGCAACGTGGAAAGCGCCCGCGACACCAGGGCCGCCACCGGCAAGCTGGTCCAGCAGGTGGACGAACTGCACCAAT
TGGTGTCGCACTTCCAGCTCTCCGACGCCATGGTCTGGGACCAGAGTTTCGCCACCAACATCGGCACGTTCGACGATCAG
CACAAGAAGCTCTTCGCCATGGTGAACGAACTGAACCAGGCCATGCAGCACAAGCGGAGCAAGGAAGCGATCGGCTCGGT
CTTGAACCGCCTGATCGAATACACCGGCAGCCACTTCGCCGCCGAGGAAGAGGCCTTCCGCAAGAGCGGCTATCCCGAGG
AAGAGGCCCACGTCAGGGCGCACCGGGACCTGGTGCAGCAGGTTGTGGCGCTGCAGCAGAAATTCAACGCCGGCGAGACC
CTCCTTACCCACGACGTCATCGAATTCCTGCAGAACTGGCTGGTCAAGCACATAAAGGGGACCGACGTCCGCTACACCTC
CCACCTGACCAAGGCCGGAGTCCGCTAA

Upstream 100 bases:

>100_bases
CCGGTTTTCTCCATATAGTTTCACTAATTGCTCAAGTTTTAAATTACGCGAGACGATAAACGACTGTGAATCTTAAATGC
CAAGATCTACAGGAGATCGT

Downstream 100 bases:

>100_bases
TCCGGCGGCTAAGCAAAAAGGGGGACAGGCTACTTTATTTTTCGAAAAAGTAGCCTGTCCCCTTTTTTTGTTTCCTGCCG
GTATTCCTCCAGCCACCCCA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MSLFSRVLTINFIAVAATIGAAVAFGSGVGLFAVGAVIILLCAVACGLSSRGETKALEEMAIALESAAAGNLSYRVTAAG
NGEIGRIGSAFNTMMGDWNKTMHQFFTVTDLVRDSVALVSATNDAMAAAAEDVALQASTIATASEEMSATSGDIARNCLY
AAENAHRATEETTSGAEIVSNSARLMENIAQRVMATSSSVAGLGERSDQIGAIAGTIEDIADQTNLLALNAAIEAARAGE
TGRGFAVVADEVRALAERTTRATKEIDAMIKSIQTETRAAVGSMGEGVEQVNQGTAETCRSGEALNGILKMINDLTMQLS
QIATAAEEQTATTHEITSNIQMITSVVNSNVESARDTRAATGKLVQQVDELHQLVSHFQLSDAMVWDQSFATNIGTFDDQ
HKKLFAMVNELNQAMQHKRSKEAIGSVLNRLIEYTGSHFAAEEEAFRKSGYPEEEAHVRAHRDLVQQVVALQQKFNAGET
LLTHDVIEFLQNWLVKHIKGTDVRYTSHLTKAGVR

Sequences:

>Translated_515_residues
MSLFSRVLTINFIAVAATIGAAVAFGSGVGLFAVGAVIILLCAVACGLSSRGETKALEEMAIALESAAAGNLSYRVTAAG
NGEIGRIGSAFNTMMGDWNKTMHQFFTVTDLVRDSVALVSATNDAMAAAAEDVALQASTIATASEEMSATSGDIARNCLY
AAENAHRATEETTSGAEIVSNSARLMENIAQRVMATSSSVAGLGERSDQIGAIAGTIEDIADQTNLLALNAAIEAARAGE
TGRGFAVVADEVRALAERTTRATKEIDAMIKSIQTETRAAVGSMGEGVEQVNQGTAETCRSGEALNGILKMINDLTMQLS
QIATAAEEQTATTHEITSNIQMITSVVNSNVESARDTRAATGKLVQQVDELHQLVSHFQLSDAMVWDQSFATNIGTFDDQ
HKKLFAMVNELNQAMQHKRSKEAIGSVLNRLIEYTGSHFAAEEEAFRKSGYPEEEAHVRAHRDLVQQVVALQQKFNAGET
LLTHDVIEFLQNWLVKHIKGTDVRYTSHLTKAGVR
>Mature_514_residues
SLFSRVLTINFIAVAATIGAAVAFGSGVGLFAVGAVIILLCAVACGLSSRGETKALEEMAIALESAAAGNLSYRVTAAGN
GEIGRIGSAFNTMMGDWNKTMHQFFTVTDLVRDSVALVSATNDAMAAAAEDVALQASTIATASEEMSATSGDIARNCLYA
AENAHRATEETTSGAEIVSNSARLMENIAQRVMATSSSVAGLGERSDQIGAIAGTIEDIADQTNLLALNAAIEAARAGET
GRGFAVVADEVRALAERTTRATKEIDAMIKSIQTETRAAVGSMGEGVEQVNQGTAETCRSGEALNGILKMINDLTMQLSQ
IATAAEEQTATTHEITSNIQMITSVVNSNVESARDTRAATGKLVQQVDELHQLVSHFQLSDAMVWDQSFATNIGTFDDQH
KKLFAMVNELNQAMQHKRSKEAIGSVLNRLIEYTGSHFAAEEEAFRKSGYPEEEAHVRAHRDLVQQVVALQQKFNAGETL
LTHDVIEFLQNWLVKHIKGTDVRYTSHLTKAGVR

Specific function: Mediates Taxis To The Sugars Ribose And Galactose VIa An Interaction With The Periplasmic Ribose- Or Galactose-Binding Proteins. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of Attractants And Repellents In The Environment, Trans

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=353, Percent_Identity=29.7450424929178, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788194, Length=327, Percent_Identity=32.7217125382263, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1788195, Length=314, Percent_Identity=30.5732484076433, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI2367378, Length=300, Percent_Identity=29, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1789453, Length=239, Percent_Identity=29.2887029288703, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 54890; Mature: 54759

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50885 HAMP ; PS00550 HEMERYTHRINS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFSRVLTINFIAVAATIGAAVAFGSGVGLFAVGAVIILLCAVACGLSSRGETKALEEM
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AIALESAAAGNLSYRVTAAGNGEIGRIGSAFNTMMGDWNKTMHQFFTVTDLVRDSVALVS
HHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ATNDAMAAAAEDVALQASTIATASEEMSATSGDIARNCLYAAENAHRATEETTSGAEIVS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
NSARLMENIAQRVMATSSSVAGLGERSDQIGAIAGTIEDIADQTNLLALNAAIEAARAGE
HHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHCCHHEEHHHHHHHHHHCCC
TGRGFAVVADEVRALAERTTRATKEIDAMIKSIQTETRAAVGSMGEGVEQVNQGTAETCR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
SGEALNGILKMINDLTMQLSQIATAAEEQTATTHEITSNIQMITSVVNSNVESARDTRAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
TGKLVQQVDELHQLVSHFQLSDAMVWDQSFATNIGTFDDQHKKLFAMVNELNQAMQHKRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KEAIGSVLNRLIEYTGSHFAAEEEAFRKSGYPEEEAHVRAHRDLVQQVVALQQKFNAGET
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
LLTHDVIEFLQNWLVKHIKGTDVRYTSHLTKAGVR
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
SLFSRVLTINFIAVAATIGAAVAFGSGVGLFAVGAVIILLCAVACGLSSRGETKALEEM
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AIALESAAAGNLSYRVTAAGNGEIGRIGSAFNTMMGDWNKTMHQFFTVTDLVRDSVALVS
HHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ATNDAMAAAAEDVALQASTIATASEEMSATSGDIARNCLYAAENAHRATEETTSGAEIVS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
NSARLMENIAQRVMATSSSVAGLGERSDQIGAIAGTIEDIADQTNLLALNAAIEAARAGE
HHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHCCHHEEHHHHHHHHHHCCC
TGRGFAVVADEVRALAERTTRATKEIDAMIKSIQTETRAAVGSMGEGVEQVNQGTAETCR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
SGEALNGILKMINDLTMQLSQIATAAEEQTATTHEITSNIQMITSVVNSNVESARDTRAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
TGKLVQQVDELHQLVSHFQLSDAMVWDQSFATNIGTFDDQHKKLFAMVNELNQAMQHKRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KEAIGSVLNRLIEYTGSHFAAEEEAFRKSGYPEEEAHVRAHRDLVQQVVALQQKFNAGET
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
LLTHDVIEFLQNWLVKHIKGTDVRYTSHLTKAGVR
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1548224 [H]