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The map label for this gene is corA-3 [H]

Identifier: 197116417

GI number: 197116417

Start: 24012

End: 24965

Strand: Direct

Name: corA-3 [H]

Synonym: Gbem_0017

Alternate gene names: 197116417

Gene position: 24012-24965 (Clockwise)

Preceding gene: 197116416

Following gene: 197116418

Centisome position: 0.52

GC content: 58.81

Gene sequence:

>954_bases
ATGCTCAGGCTTTTCAGCATAGACAACGGGCTAATAAAGGAGATGGACTTTGAGAAAAGCGATCTCCCCAATCAGATCCT
GCATGCCGACTGGATCGACGCCCATGAGCCGGATGACGAAGAGAGGGACCTGCTCGAGCTGTTGCTGCACACCGACATTC
CGGAGTCCGACGAGGTGGACGAGATCGAGATCTCAGCCCGCTGCTTCGTGGACCAGGCCGGGATACACGTGCATCCCCTG
TTCCTTTCCCAGAGCGAGGGGCGCCACGTGACGCTCACCGTCGCCTGTATTCTGCAAAGCAAGCACCTGATCACCATCCG
GGAAGGGGACCTCGCCGACTTCCGGCTCCTGCGCATGCGCGCCAGGAGAGGGCAGGTGGAATGCCGCACCCCGTCCGAGC
TTCTCGTGCTGCTCCTGGACCAGAAGGTAGAGAACCACGCGGACACCCTGGAGGACATCCACCGCCAGCTGGAAGGGGTA
AGCCACCTGGTGCTCGAAGACGATGATTCCGAGTTGGAAGACGCCATCAGCAAGCTCGCCAAGCTCGAGGACAGCAACGG
AAAGATCCGGCTCTGCCTGATGGATACCCAGAGGGACATCTCGTTCCTTTTGCGGCACCTGCGCGACCGGGCCGATCAGA
GCGAGACGCTGCGTGAGATCGCCCGCGACGTCGAGACCCTTATGTCGCATACCACCTTCCTTTTCGATAAGATCAACTTC
CTGATGGACTCCACCCAGGGTTTCATCAACATCGAGCAGAACCAGATCATCAAGATCTTTTCCATCGCAGCCGTGGTCTT
CCTCCCCCCTACCCTCGTCGCCAGCATCTACGGGATGAACTTCGACGTGATGCCCGAGCTGAAACTCTCTTTCGGCTACC
CCTGGGCTCTCGCGCTGATGATTCTCTCAGGCATCGCTCCCTACTGGTACTTCAAGCGCAAGGGTTGGCTCTAA

Upstream 100 bases:

>100_bases
CGGCCGATGAGGCCGCCCTTTTTCTTGACCAGGCAACAAAGGATCCGGTCGAATTTCGCAGGCCACGGCTGCCTGCCGCA
CCGGATCAGCGGGAGTAGAC

Downstream 100 bases:

>100_bases
AACTACATAATTCAAAGTCAAAGAGACAGGGCTGCCGTCGCGAAAGGCACACTGTCAGTTGCACCGCTGCCCGATACCGT
TCCTCAGTCTGGACCGACCC

Product: magnesium transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MLRLFSIDNGLIKEMDFEKSDLPNQILHADWIDAHEPDDEERDLLELLLHTDIPESDEVDEIEISARCFVDQAGIHVHPL
FLSQSEGRHVTLTVACILQSKHLITIREGDLADFRLLRMRARRGQVECRTPSELLVLLLDQKVENHADTLEDIHRQLEGV
SHLVLEDDDSELEDAISKLAKLEDSNGKIRLCLMDTQRDISFLLRHLRDRADQSETLREIARDVETLMSHTTFLFDKINF
LMDSTQGFINIEQNQIIKIFSIAAVVFLPPTLVASIYGMNFDVMPELKLSFGYPWALALMILSGIAPYWYFKRKGWL

Sequences:

>Translated_317_residues
MLRLFSIDNGLIKEMDFEKSDLPNQILHADWIDAHEPDDEERDLLELLLHTDIPESDEVDEIEISARCFVDQAGIHVHPL
FLSQSEGRHVTLTVACILQSKHLITIREGDLADFRLLRMRARRGQVECRTPSELLVLLLDQKVENHADTLEDIHRQLEGV
SHLVLEDDDSELEDAISKLAKLEDSNGKIRLCLMDTQRDISFLLRHLRDRADQSETLREIARDVETLMSHTTFLFDKINF
LMDSTQGFINIEQNQIIKIFSIAAVVFLPPTLVASIYGMNFDVMPELKLSFGYPWALALMILSGIAPYWYFKRKGWL
>Mature_317_residues
MLRLFSIDNGLIKEMDFEKSDLPNQILHADWIDAHEPDDEERDLLELLLHTDIPESDEVDEIEISARCFVDQAGIHVHPL
FLSQSEGRHVTLTVACILQSKHLITIREGDLADFRLLRMRARRGQVECRTPSELLVLLLDQKVENHADTLEDIHRQLEGV
SHLVLEDDDSELEDAISKLAKLEDSNGKIRLCLMDTQRDISFLLRHLRDRADQSETLREIARDVETLMSHTTFLFDKINF
LMDSTQGFINIEQNQIIKIFSIAAVVFLPPTLVASIYGMNFDVMPELKLSFGYPWALALMILSGIAPYWYFKRKGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=319, Percent_Identity=48.2758620689655, Blast_Score=288, Evalue=3e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36523; Mature: 36523

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRLFSIDNGLIKEMDFEKSDLPNQILHADWIDAHEPDDEERDLLELLLHTDIPESDEVD
CEEEEECCCCHHHHCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
EIEISARCFVDQAGIHVHPLFLSQSEGRHVTLTVACILQSKHLITIREGDLADFRLLRMR
CEEEEHEEEEECCCCEEEEEEEECCCCCEEEEEEEEEECCCCEEEEECCCHHHHHHHHHH
ARRGQVECRTPSELLVLLLDQKVENHADTLEDIHRQLEGVSHLVLEDDDSELEDAISKLA
HHCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHH
KLEDSNGKIRLCLMDTQRDISFLLRHLRDRADQSETLREIARDVETLMSHTTFLFDKINF
HCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMDSTQGFINIEQNQIIKIFSIAAVVFLPPTLVASIYGMNFDVMPELKLSFGYPWALALM
HHHCCCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHH
ILSGIAPYWYFKRKGWL
HHHCCCHHHHHHCCCCC
>Mature Secondary Structure
MLRLFSIDNGLIKEMDFEKSDLPNQILHADWIDAHEPDDEERDLLELLLHTDIPESDEVD
CEEEEECCCCHHHHCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
EIEISARCFVDQAGIHVHPLFLSQSEGRHVTLTVACILQSKHLITIREGDLADFRLLRMR
CEEEEHEEEEECCCCEEEEEEEECCCCCEEEEEEEEEECCCCEEEEECCCHHHHHHHHHH
ARRGQVECRTPSELLVLLLDQKVENHADTLEDIHRQLEGVSHLVLEDDDSELEDAISKLA
HHCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHH
KLEDSNGKIRLCLMDTQRDISFLLRHLRDRADQSETLREIARDVETLMSHTTFLFDKINF
HCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMDSTQGFINIEQNQIIKIFSIAAVVFLPPTLVASIYGMNFDVMPELKLSFGYPWALALM
HHHCCCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHH
ILSGIAPYWYFKRKGWL
HHHCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]