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The map label for this gene is engD [H]

Identifier: 197106326

GI number: 197106326

Start: 3277308

End: 3278405

Strand: Direct

Name: engD [H]

Synonym: PHZ_c2865

Alternate gene names: 197106326

Gene position: 3277308-3278405 (Clockwise)

Preceding gene: 197106325

Following gene: 197106327

Centisome position: 82.01

GC content: 68.76

Gene sequence:

>1098_bases
ATGGCTCTGAAAGTCGCCATCGTCGGCCTGCCGAACGTCGGCAAGTCGACCCTCTTTAACGCGCTCACCCAGACCGCCGC
GGCCCAGGCCGCGAACTATCCCTTCTGCACCATCGAGCCTAACGTGGGCGACGTGGCCGTGCCCGAGCCGCGCCTGGAGG
CGCTGGCCAAGATCATCCCGTCCAAGGAGATCATCCCGGCCCGCATCAACTTCGTGGACGTCGCCGGCCTGGTGCGCGGC
GCGTCCAAGGGCGAGGGCCTGGGCAACCAGTTCCTGGCCAACATCCGCGACTGCGACGCCGTCTGCTTCGTCGCCCGCTG
CTTCATCGACGACGACATCACCCACGTCGAGGGCCGGGTCGATCCGCTCGCCGACCTCGACACCATCGAGACCGAGCTGA
TGCTGGCCGACATGGAGAGCCTGGAGAAGCGGGTGGTGAACCTCGAGAAGCGCGCCAAGGTCGGCGACAAGGAGGCCGCC
CAGACGCTGCGCCTGATCAAGCTGGCGCTCGCCGAGCTGAACGAGGGCCGCCCGGCCCGCGTCGCCAAGATCGCCGCCGA
GGACGAGAAGGCCTGGCGGATGCTTCAGCTCCTGACGTCCAAGCCGGCCCTCTACGTCGCCAACGTCGACGAGGGCTCGG
CCGCCACCGGCAACGAGCTCTCGAAGGCCGTGCAGGAGCGCGCCGCCCGCGACGGGGCCGACAGCGTCGTCATCTCGGCC
AAGATCGAGAGCGAGATCGCCCTGCTCGAGCCCGAGGAGCGCGCCGAGTTCCTCGAGACCCTGGGCCTGGAGGAGCCGGG
CCTGAACCGCCTGATCCGCGAGGCCTACCACCTGCTCGGCCTGCAGACCTACTTCACCGTGGGTCCCAAGGAGGCGCGCG
CCTGGACGATCCACAAGGGCGACACCGCCCCCCAGGCCGCCGGCGTCATCCACACCGACTTCGAGAAGGGCTTCATCCGC
GCCGAGACGATCGCCTACGAGGACTACGTCCGCCTGGGCGGCGAGGCGGGCGCGAGAGACGCCGGCAAGCTGCGCTCGGA
AGGCAAGGAGTACGTCGTCAAGGACGGCGACGTGATGAACTTCCGCTTCAACGTCTAG

Upstream 100 bases:

>100_bases
GCCGACCCCCGCAAGCTGGCCCAAGGGAAGCCCCGGGGGGAATGACGCCTCCGGCGGCCCGTGCTAGGTCCGCCGCCACA
CTAGGAAACCCGAAAGTCTC

Downstream 100 bases:

>100_bases
GACGGTATCCACGCAGAAGCTGGTCGCAGCGCCACGCGAGCAGAAACCAACAGGGGAGCGTGATGTCGGCTGAAGAGACC
TTTCCGGCGAAGCTCGTCTT

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MALKVAIVGLPNVGKSTLFNALTQTAAAQAANYPFCTIEPNVGDVAVPEPRLEALAKIIPSKEIIPARINFVDVAGLVRG
ASKGEGLGNQFLANIRDCDAVCFVARCFIDDDITHVEGRVDPLADLDTIETELMLADMESLEKRVVNLEKRAKVGDKEAA
QTLRLIKLALAELNEGRPARVAKIAAEDEKAWRMLQLLTSKPALYVANVDEGSAATGNELSKAVQERAARDGADSVVISA
KIESEIALLEPEERAEFLETLGLEEPGLNRLIREAYHLLGLQTYFTVGPKEARAWTIHKGDTAPQAAGVIHTDFEKGFIR
AETIAYEDYVRLGGEAGARDAGKLRSEGKEYVVKDGDVMNFRFNV

Sequences:

>Translated_365_residues
MALKVAIVGLPNVGKSTLFNALTQTAAAQAANYPFCTIEPNVGDVAVPEPRLEALAKIIPSKEIIPARINFVDVAGLVRG
ASKGEGLGNQFLANIRDCDAVCFVARCFIDDDITHVEGRVDPLADLDTIETELMLADMESLEKRVVNLEKRAKVGDKEAA
QTLRLIKLALAELNEGRPARVAKIAAEDEKAWRMLQLLTSKPALYVANVDEGSAATGNELSKAVQERAARDGADSVVISA
KIESEIALLEPEERAEFLETLGLEEPGLNRLIREAYHLLGLQTYFTVGPKEARAWTIHKGDTAPQAAGVIHTDFEKGFIR
AETIAYEDYVRLGGEAGARDAGKLRSEGKEYVVKDGDVMNFRFNV
>Mature_364_residues
ALKVAIVGLPNVGKSTLFNALTQTAAAQAANYPFCTIEPNVGDVAVPEPRLEALAKIIPSKEIIPARINFVDVAGLVRGA
SKGEGLGNQFLANIRDCDAVCFVARCFIDDDITHVEGRVDPLADLDTIETELMLADMESLEKRVVNLEKRAKVGDKEAAQ
TLRLIKLALAELNEGRPARVAKIAAEDEKAWRMLQLLTSKPALYVANVDEGSAATGNELSKAVQERAARDGADSVVISAK
IESEIALLEPEERAEFLETLGLEEPGLNRLIREAYHLLGLQTYFTVGPKEARAWTIHKGDTAPQAAGVIHTDFEKGFIRA
ETIAYEDYVRLGGEAGARDAGKLRSEGKEYVVKDGDVMNFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=370, Percent_Identity=42.7027027027027, Blast_Score=286, Evalue=3e-77,
Organism=Homo sapiens, GI58761502, Length=172, Percent_Identity=41.8604651162791, Blast_Score=138, Evalue=8e-33,
Organism=Escherichia coli, GI1787454, Length=365, Percent_Identity=55.8904109589041, Blast_Score=414, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=40.9836065573771, Blast_Score=266, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6319499, Length=369, Percent_Identity=38.7533875338753, Blast_Score=241, Evalue=1e-64,
Organism=Saccharomyces cerevisiae, GI6321773, Length=380, Percent_Identity=34.4736842105263, Blast_Score=207, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6321649, Length=178, Percent_Identity=34.2696629213483, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24640873, Length=367, Percent_Identity=43.3242506811989, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24640877, Length=367, Percent_Identity=43.3242506811989, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24640875, Length=367, Percent_Identity=43.3242506811989, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24640879, Length=325, Percent_Identity=40.6153846153846, Blast_Score=230, Evalue=1e-60,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39643; Mature: 39511

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALKVAIVGLPNVGKSTLFNALTQTAAAQAANYPFCTIEPNVGDVAVPEPRLEALAKIIP
CEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHCC
SKEIIPARINFVDVAGLVRGASKGEGLGNQFLANIRDCDAVCFVARCFIDDDITHVEGRV
CCCCCEEECCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCC
DPLADLDTIETELMLADMESLEKRVVNLEKRAKVGDKEAAQTLRLIKLALAELNEGRPAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCH
VAKIAAEDEKAWRMLQLLTSKPALYVANVDEGSAATGNELSKAVQERAARDGADSVVISA
HHEEHHCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEE
KIESEIALLEPEERAEFLETLGLEEPGLNRLIREAYHLLGLQTYFTVGPKEARAWTIHKG
EECCCEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCEEEEECC
DTAPQAAGVIHTDFEKGFIRAETIAYEDYVRLGGEAGARDAGKLRSEGKEYVVKDGDVMN
CCCCCCCCCEEECCCCCCEEHHHHHHHHHHHHCCCCCCCCHHHHHHCCCEEEEECCCEEE
FRFNV
EEECC
>Mature Secondary Structure 
ALKVAIVGLPNVGKSTLFNALTQTAAAQAANYPFCTIEPNVGDVAVPEPRLEALAKIIP
EEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHCC
SKEIIPARINFVDVAGLVRGASKGEGLGNQFLANIRDCDAVCFVARCFIDDDITHVEGRV
CCCCCEEECCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCC
DPLADLDTIETELMLADMESLEKRVVNLEKRAKVGDKEAAQTLRLIKLALAELNEGRPAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCH
VAKIAAEDEKAWRMLQLLTSKPALYVANVDEGSAATGNELSKAVQERAARDGADSVVISA
HHEEHHCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEE
KIESEIALLEPEERAEFLETLGLEEPGLNRLIREAYHLLGLQTYFTVGPKEARAWTIHKG
EECCCEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCEEEEECC
DTAPQAAGVIHTDFEKGFIRAETIAYEDYVRLGGEAGARDAGKLRSEGKEYVVKDGDVMN
CCCCCCCCCEEECCCCCCEEHHHHHHHHHHHHCCCCCCCCHHHHHHCCCEEEEECCCEEE
FRFNV
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]