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The map label for this gene is paaG [C]

Identifier: 197106011

GI number: 197106011

Start: 2926996

End: 2927802

Strand: Reverse

Name: paaG [C]

Synonym: PHZ_c2550

Alternate gene names: 197106011

Gene position: 2927802-2926996 (Counterclockwise)

Preceding gene: 197106012

Following gene: 197106010

Centisome position: 73.26

GC content: 70.01

Gene sequence:

>807_bases
ATGTCCGACACCGTGCTCGTCAGCCGCGAAGAGGGGGTCGCGATCGTCACCCTCAACCGGCCGGAACACCTCAACGCCAT
GACCTCGGAGCTGATGGACCGGCTGCCCGAGGTGGTCGCCGAACTGGCGCGTGACCCCCAGGTGGGCTGCGTCGTGCTCA
CCGGCGCGGGACGCGGTTTCTGCGCCGGCGGCGACCTGAAGAGCCGGCAGGCCGAGCTGGACGCCCAGGCCGGCCTGTCC
GACGCCGAGCGCGCCGCCCACAACATGCCCGTGAACATGGAAAGCGTGCTCAAGGCGCGGGAGGAGGCGGCGCGGCTGCT
GCACGACATGGCCAAGCCGACCATCGCCATGGTCAACGGCCCCTGTGCGGGCGCGGGCTTCAGCCTGGCCGGCGCGTGCG
ACATGCGTCTTGCCGCGGAGACGGCGTTCTTCACGAGCGCCTTCACCCGCGCGGGTCTGTCGGGAGATTTCGGCGGGACC
TATTTCTGGACCAAGATCCTTGGCACGGCCAAGGCGAGGGAGCTCTACTTCCTCTCCGAGCGCATCGACGCCCAGACGGC
GCTGGCCTGGGGCATGGTCAACCGCGTCTATCCGGACGCCGAGCTGCGCGAGCGGACGCTCGAGATCGCCAAGCGCATCG
CCGGCGGGCCGCGCTGGGCCTACGGCAACGCCAAGCGCAACCTGAACGCGGCCGAGGACAGCAGCCTGGACCGGGTGCTG
CTGTCCGAGGCGATCACCATGGGAATCTCGGCCCGGACCACCCGCGAGATGGGCTTCCTCCCCAGCACCGTCCTGGCGAA
GCGATGA

Upstream 100 bases:

>100_bases
CAAGTGGATCGTCCACGCCCTACAGTGCGCCCAGCACACAGGCGAGCCGCCAGGCGCCCATCCCTTCATTCACACCTGGT
GATCTGCAGAGGGCCATCGA

Downstream 100 bases:

>100_bases
GCGCGGACGTCCTCCTCGACCGCCCGGCGCCGCGCGTGGCGCGGATCACGCTCAACACGCCGGAAACCCGCAACGCGGCC
AGTCCAGGTCGCACCAAGCT

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSDTVLVSREEGVAIVTLNRPEHLNAMTSELMDRLPEVVAELARDPQVGCVVLTGAGRGFCAGGDLKSRQAELDAQAGLS
DAERAAHNMPVNMESVLKAREEAARLLHDMAKPTIAMVNGPCAGAGFSLAGACDMRLAAETAFFTSAFTRAGLSGDFGGT
YFWTKILGTAKARELYFLSERIDAQTALAWGMVNRVYPDAELRERTLEIAKRIAGGPRWAYGNAKRNLNAAEDSSLDRVL
LSEAITMGISARTTREMGFLPSTVLAKR

Sequences:

>Translated_268_residues
MSDTVLVSREEGVAIVTLNRPEHLNAMTSELMDRLPEVVAELARDPQVGCVVLTGAGRGFCAGGDLKSRQAELDAQAGLS
DAERAAHNMPVNMESVLKAREEAARLLHDMAKPTIAMVNGPCAGAGFSLAGACDMRLAAETAFFTSAFTRAGLSGDFGGT
YFWTKILGTAKARELYFLSERIDAQTALAWGMVNRVYPDAELRERTLEIAKRIAGGPRWAYGNAKRNLNAAEDSSLDRVL
LSEAITMGISARTTREMGFLPSTVLAKR
>Mature_267_residues
SDTVLVSREEGVAIVTLNRPEHLNAMTSELMDRLPEVVAELARDPQVGCVVLTGAGRGFCAGGDLKSRQAELDAQAGLSD
AERAAHNMPVNMESVLKAREEAARLLHDMAKPTIAMVNGPCAGAGFSLAGACDMRLAAETAFFTSAFTRAGLSGDFGGTY
FWTKILGTAKARELYFLSERIDAQTALAWGMVNRVYPDAELRERTLEIAKRIAGGPRWAYGNAKRNLNAAEDSSLDRVLL
SEAITMGISARTTREMGFLPSTVLAKR

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=228, Percent_Identity=32.8947368421053, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI70995211, Length=233, Percent_Identity=31.3304721030043, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI260274832, Length=215, Percent_Identity=29.3023255813954, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI45643119, Length=215, Percent_Identity=29.3023255813954, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI260275230, Length=215, Percent_Identity=29.3023255813954, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI37594469, Length=182, Percent_Identity=29.6703296703297, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI37594471, Length=182, Percent_Identity=29.6703296703297, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI31542718, Length=248, Percent_Identity=26.2096774193548, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI116235487, Length=194, Percent_Identity=26.8041237113402, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI221136756, Length=194, Percent_Identity=26.8041237113402, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI221136753, Length=194, Percent_Identity=26.8041237113402, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI221307494, Length=194, Percent_Identity=26.8041237113402, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4757968, Length=194, Percent_Identity=26.2886597938144, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI49355787, Length=194, Percent_Identity=26.2886597938144, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4757966, Length=194, Percent_Identity=26.2886597938144, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI51538581, Length=194, Percent_Identity=26.2886597938144, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI25453481, Length=194, Percent_Identity=26.2886597938144, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI51538573, Length=194, Percent_Identity=26.2886597938144, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI157694516, Length=247, Percent_Identity=24.2914979757085, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI213417737, Length=247, Percent_Identity=24.2914979757085, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787660, Length=240, Percent_Identity=36.6666666666667, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1788597, Length=227, Percent_Identity=31.7180616740088, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787659, Length=239, Percent_Identity=31.7991631799163, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI221142681, Length=214, Percent_Identity=32.2429906542056, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082183, Length=204, Percent_Identity=27.9411764705882, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788682, Length=208, Percent_Identity=23.5576923076923, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=230, Percent_Identity=33.0434782608696, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17536985, Length=234, Percent_Identity=29.9145299145299, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17535521, Length=209, Percent_Identity=31.5789473684211, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17540714, Length=244, Percent_Identity=30.327868852459, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17554946, Length=237, Percent_Identity=29.1139240506329, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17549921, Length=212, Percent_Identity=30.6603773584906, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17534483, Length=230, Percent_Identity=27.3913043478261, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17560910, Length=217, Percent_Identity=26.2672811059908, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24654903, Length=200, Percent_Identity=31, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19920382, Length=215, Percent_Identity=31.1627906976744, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI20129971, Length=233, Percent_Identity=28.755364806867, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24653477, Length=233, Percent_Identity=28.755364806867, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24650670, Length=215, Percent_Identity=28.8372093023256, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24653139, Length=215, Percent_Identity=29.7674418604651, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21357171, Length=244, Percent_Identity=23.3606557377049, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI19922422, Length=217, Percent_Identity=26.7281105990783, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 28842; Mature: 28711

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTVLVSREEGVAIVTLNRPEHLNAMTSELMDRLPEVVAELARDPQVGCVVLTGAGRGF
CCCCEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCE
CAGGDLKSRQAELDAQAGLSDAERAAHNMPVNMESVLKAREEAARLLHDMAKPTIAMVNG
ECCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECC
PCAGAGFSLAGACDMRLAAETAFFTSAFTRAGLSGDFGGTYFWTKILGTAKARELYFLSE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RIDAQTALAWGMVNRVYPDAELRERTLEIAKRIAGGPRWAYGNAKRNLNAAEDSSLDRVL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCHHHHHHH
LSEAITMGISARTTREMGFLPSTVLAKR
HHHHHHHCCCHHHHHHHCCCCHHHHCCC
>Mature Secondary Structure 
SDTVLVSREEGVAIVTLNRPEHLNAMTSELMDRLPEVVAELARDPQVGCVVLTGAGRGF
CCCEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCE
CAGGDLKSRQAELDAQAGLSDAERAAHNMPVNMESVLKAREEAARLLHDMAKPTIAMVNG
ECCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECC
PCAGAGFSLAGACDMRLAAETAFFTSAFTRAGLSGDFGGTYFWTKILGTAKARELYFLSE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RIDAQTALAWGMVNRVYPDAELRERTLEIAKRIAGGPRWAYGNAKRNLNAAEDSSLDRVL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCHHHHHHH
LSEAITMGISARTTREMGFLPSTVLAKR
HHHHHHHCCCHHHHHHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA