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The map label for this gene is accC [H]

Identifier: 197106012

GI number: 197106012

Start: 2927821

End: 2931117

Strand: Reverse

Name: accC [H]

Synonym: PHZ_c2551

Alternate gene names: 197106012

Gene position: 2931117-2927821 (Counterclockwise)

Preceding gene: 197106013

Following gene: 197106011

Centisome position: 73.35

GC content: 70.94

Gene sequence:

>3297_bases
ATGGCCATACAGCGACTGCTCATTGCGAACCGCGGCGAGATCGCGATCCGGATCGCCCGCGCCGCGGATGAACTGGGCAT
GGCAACCGTCGCGATCTGTTCCGAGGACGACCGCGGCTCGCTCCACACGGCCAAGGCCGACGACCTGCACGTGCTGTCGG
GGGTGGGCGCCAAGGCGTACCTCGACATCGAGCAAGTGCTCGCCGCCGCCCGGACGGCGGGTTGCGACGCCATCCATCCC
GGCTACGGCTTCCTCGCCGAGAACGCCCAGTTCGCGGCGCGATGCGCCGAGCAGGACATAACCTTCGTCGGCCCCACCCC
CGAGATGCTGACGGAGTTCGGCGACAAGGCGCGGGCCCGTTCGCTGGCGCGCGACTGCGGCGTTCCCACTCCGCAAGGGC
TCTTCGAGCCAAGCACGCTGGAACAGGCGGAGGCGTTCCTGGCCTCGCTCGAGCCGGGCGCGGCCGTGATCCTGAAAGCG
GTGGCCGGCGGCGGCGGCCGGGGAATCCGCGTGGTCCGGACGCCGAAGGAGCTTCCGAAGGCCTTCGAGCGGTGCAGTTC
CGAGGCCAAGGCGGCCTTCGGGCAGGGCGACCTCTACGTGGAGCGTTTCCTGCCGCGGGCGCGGCACCTGGAGGTGCAGA
TCATCGGCGACGGCCAGGGCGGGGTGACCCATCTGTGGGAGCGGGAATGCACCCTGCAGCGCCGCCATCAGAAGATCGTG
GAGATCGCGCCCAGTCCCGACCTCCCGGAGGCGCTCCGGGAGGCGTTGCTGGACGCGTCGGTGCGGCTGGCGACCGCGGT
CGGCTATCGTGGCCTGGGCACGTTCGAGTTCCTGGTTTGGGACTCGCCGGCGAAGGGCGGGCTGGACTTCGCCTTCATCG
AGGCCAATCCACGGATCCAGGTCGAGCACACCGTGACCGAAGAAGTCACCGGGGTCGATCTCGTGCAGGCGCAGCTCCGC
GTCGCCGGGGGCGCATCGCTGGCCTCGCTCGGCCTGACGCAGGACCGGATCGCTCCCCCGCGCGGTCACGCCATCCAGCT
GCGGGTGAACATGGAGCGCATGACGCCGGATGGCGCCGTTCTGCCCTCGGGCGGACAGCTCACCGCGTTTGATCCGCCCT
CCGGACCCGGGATGCGGACCGATACGTTCGGCTATGCGGGCTACCGCACCAGCCCAAACTTCGACTCGCTGCTGGCGAAG
GTGATCGTCCACTCGCCCGAGCCAGACTTCGCCGCCGCCCTGCGGCGCGGCCGGCGGGCGCTGCGCGAGTTCCGCATTGG
CGGGGTGCCCACCAACCTGGAGTTCCTCCACGCCCTTATCAGCCGGCCCGAGGTCGCGGCGAACGATATCTACACGACCT
TCATCGACGACCATGTGCGCGAGCTCGCGGCCGCGGCCGAGGCGCATGTGGGAGGACTGTTCTTCGCCCAGGCGGCGGAG
AGCGAGTCCGCGCCCGAGACCGCAGCCGACCTCGGGGCCGCCGCGCCCGCCGGAATGCCCGTGAGCGCGCCGCTGCAGGG
CACCATCGTGGCCCTCTCGGTGAAGGTCGGCGACGAGGTTCCCGCCGGCGGGCAGGTGGCCGTGATCGAGGCCATGAAGA
TGGAGCACGTGGTGCGCGCGCCGTGCAGCGGCGTCATCAGCGGCCTGAACGTCACTCCGGCCGAGACGGTGTTCGAAGGT
CACCCGCTGCTCTGGATCGAGGCGGGCGAGGTGCAGGTCGAGGCGGCGGCGGCGCAGGCGGAACCGGACCCGGACCACGT
TCGCGCCGATCTCGCCGCCGTGCTGGAGCGGCACGCGCTCACCCGCGACGAGGCCCGGCCGGACGCCGTGGCGAAGCGCC
GGCGGCGCAACCAGAGGACGGCGCGGGAGAACGTCGCGGCGGTGTGCGATCCGGACACCTTCGTCGAATACGGGCCCCTG
GTGGTGGCGGCCCAGCGCGGGCGGCGCTCGCTGGACGAGCTGATCCGCACCACGCCGGCCGATGGGCTGGTGGCGGGCTT
CGGGACCGTCAACGGCAGCCTCTTCGGAGCGAACGCGCGGTGCCTGGTGCTGGCCTATGACGCCACCGTACTGGCCGGGA
CCCAGGGCCGGGAGGGCCACCGCAAGGACCAGCGGCTGTTCGAGCTGGCCGAGCGGCTCCGCACGCCGGTGATCTTCTTC
GCCGAGGGCGGCGGCGGGCGGCCCGGCGACACCGAGCGCACGGGCGAGGGCCTGTCGTTCCACTATTTCGCCCGTCTCAG
CGGGAAGGTCCCGCTGGTGGGGGTGACCGCCGGCTACTGCTTCGCCGGCAACACCGCCTTCCTCGGCTGCTGCCACGTGA
TCATCGCCACCCGAAACGCCAACATCGGCATGGGCGGGCCGGCGATGGTCGAGGGCGGCGGGCTCGGGGTCTTCAGCGCC
GACGAGATCGGCCCGGCCACGATGCACTACGCACGGGGCGCGGTGGACGTACTCGTGGAGGACGAGGTCGAGGCGGCCGC
CGCGGCCAAGCGCTACCTGAGCTATTTCCAGGGCGACGTCGCGCCCGGGCCCTGCGCCGATCAGCGGCGGCTGCGCCACC
TGGTGCCGGAGGACCGGCGACGGGCCTACGACATCCGACCGGTCATCGAGACCCTCGTCGACGAAGGCTCGATGTTCGAG
CTGCGCGGCGGCTGGGGTCACGGCGTGGTGACGGCGCTCGCCCGCATTGAGGGCAAGGCGGTGGGGATCGTCGCCAACAA
CCCCATGCACCTGGCGGGGGCGATCGATGCGGAAGCGGGCGACAAGGGCGCGCGTTTCCTGCAACTCTGCGACAACTTCG
GCCTGCCGGTCGTTCACCTCTGCGACACCCCCGGGATCATGGTGGGACCCGAGGCCGAGAAGACGGCGCTGATCCGGCGG
GCGTGCAACCTGCTGGTCGCCGGCGCGAACCTCAGGGTCCCGAGCTGCACCATCATCGTGCGCAAGTTCTACGGGCTTGG
GATGATCGCCATGATGGGCGGGGCCTTCAAGGCACCGATCTTCACCGTCGCCTGGCCCACCGGGGAGTACGGCGCCATGG
GCCTGGAGGGCGCGGTGCGGCTGGCCTACCGCAAGGAGCTCGAGGCGATCGAGGACCCTGCCGAGCGCAAGGCGGTCTAC
GACCAGCGCGTCGAGGAGATGTATCAGGAGGGCAAGGCGCTCCAGAAGGCGTCCTCGTACGACTTCGACGACGTGATCGA
TCCCGCCGACTCCCGCAAGTGGATCGTCCACGCCCTACAGTGCGCCCAGCACACAGGCGAGCCGCCAGGCGCCCATCCCT
TCATTCACACCTGGTGA

Upstream 100 bases:

>100_bases
AACACGGTGGCGGCGCCACGACGGCGTCGCCCCCGCAACGCTGTCTGCGCGCCCGGCGAGCCGCGGCGCGCACTGACCTT
ACTCGCCCGGGAAACCTCCG

Downstream 100 bases:

>100_bases
TCTGCAGAGGGCCATCGAATGTCCGACACCGTGCTCGTCAGCCGCGAAGAGGGGGTCGCGATCGTCACCCTCAACCGGCC
GGAACACCTCAACGCCATGA

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Acetyl-CoA carboxylase subunit A; ACC [H]

Number of amino acids: Translated: 1098; Mature: 1097

Protein sequence:

>1098_residues
MAIQRLLIANRGEIAIRIARAADELGMATVAICSEDDRGSLHTAKADDLHVLSGVGAKAYLDIEQVLAAARTAGCDAIHP
GYGFLAENAQFAARCAEQDITFVGPTPEMLTEFGDKARARSLARDCGVPTPQGLFEPSTLEQAEAFLASLEPGAAVILKA
VAGGGGRGIRVVRTPKELPKAFERCSSEAKAAFGQGDLYVERFLPRARHLEVQIIGDGQGGVTHLWERECTLQRRHQKIV
EIAPSPDLPEALREALLDASVRLATAVGYRGLGTFEFLVWDSPAKGGLDFAFIEANPRIQVEHTVTEEVTGVDLVQAQLR
VAGGASLASLGLTQDRIAPPRGHAIQLRVNMERMTPDGAVLPSGGQLTAFDPPSGPGMRTDTFGYAGYRTSPNFDSLLAK
VIVHSPEPDFAAALRRGRRALREFRIGGVPTNLEFLHALISRPEVAANDIYTTFIDDHVRELAAAAEAHVGGLFFAQAAE
SESAPETAADLGAAAPAGMPVSAPLQGTIVALSVKVGDEVPAGGQVAVIEAMKMEHVVRAPCSGVISGLNVTPAETVFEG
HPLLWIEAGEVQVEAAAAQAEPDPDHVRADLAAVLERHALTRDEARPDAVAKRRRRNQRTARENVAAVCDPDTFVEYGPL
VVAAQRGRRSLDELIRTTPADGLVAGFGTVNGSLFGANARCLVLAYDATVLAGTQGREGHRKDQRLFELAERLRTPVIFF
AEGGGGRPGDTERTGEGLSFHYFARLSGKVPLVGVTAGYCFAGNTAFLGCCHVIIATRNANIGMGGPAMVEGGGLGVFSA
DEIGPATMHYARGAVDVLVEDEVEAAAAAKRYLSYFQGDVAPGPCADQRRLRHLVPEDRRRAYDIRPVIETLVDEGSMFE
LRGGWGHGVVTALARIEGKAVGIVANNPMHLAGAIDAEAGDKGARFLQLCDNFGLPVVHLCDTPGIMVGPEAEKTALIRR
ACNLLVAGANLRVPSCTIIVRKFYGLGMIAMMGGAFKAPIFTVAWPTGEYGAMGLEGAVRLAYRKELEAIEDPAERKAVY
DQRVEEMYQEGKALQKASSYDFDDVIDPADSRKWIVHALQCAQHTGEPPGAHPFIHTW

Sequences:

>Translated_1098_residues
MAIQRLLIANRGEIAIRIARAADELGMATVAICSEDDRGSLHTAKADDLHVLSGVGAKAYLDIEQVLAAARTAGCDAIHP
GYGFLAENAQFAARCAEQDITFVGPTPEMLTEFGDKARARSLARDCGVPTPQGLFEPSTLEQAEAFLASLEPGAAVILKA
VAGGGGRGIRVVRTPKELPKAFERCSSEAKAAFGQGDLYVERFLPRARHLEVQIIGDGQGGVTHLWERECTLQRRHQKIV
EIAPSPDLPEALREALLDASVRLATAVGYRGLGTFEFLVWDSPAKGGLDFAFIEANPRIQVEHTVTEEVTGVDLVQAQLR
VAGGASLASLGLTQDRIAPPRGHAIQLRVNMERMTPDGAVLPSGGQLTAFDPPSGPGMRTDTFGYAGYRTSPNFDSLLAK
VIVHSPEPDFAAALRRGRRALREFRIGGVPTNLEFLHALISRPEVAANDIYTTFIDDHVRELAAAAEAHVGGLFFAQAAE
SESAPETAADLGAAAPAGMPVSAPLQGTIVALSVKVGDEVPAGGQVAVIEAMKMEHVVRAPCSGVISGLNVTPAETVFEG
HPLLWIEAGEVQVEAAAAQAEPDPDHVRADLAAVLERHALTRDEARPDAVAKRRRRNQRTARENVAAVCDPDTFVEYGPL
VVAAQRGRRSLDELIRTTPADGLVAGFGTVNGSLFGANARCLVLAYDATVLAGTQGREGHRKDQRLFELAERLRTPVIFF
AEGGGGRPGDTERTGEGLSFHYFARLSGKVPLVGVTAGYCFAGNTAFLGCCHVIIATRNANIGMGGPAMVEGGGLGVFSA
DEIGPATMHYARGAVDVLVEDEVEAAAAAKRYLSYFQGDVAPGPCADQRRLRHLVPEDRRRAYDIRPVIETLVDEGSMFE
LRGGWGHGVVTALARIEGKAVGIVANNPMHLAGAIDAEAGDKGARFLQLCDNFGLPVVHLCDTPGIMVGPEAEKTALIRR
ACNLLVAGANLRVPSCTIIVRKFYGLGMIAMMGGAFKAPIFTVAWPTGEYGAMGLEGAVRLAYRKELEAIEDPAERKAVY
DQRVEEMYQEGKALQKASSYDFDDVIDPADSRKWIVHALQCAQHTGEPPGAHPFIHTW
>Mature_1097_residues
AIQRLLIANRGEIAIRIARAADELGMATVAICSEDDRGSLHTAKADDLHVLSGVGAKAYLDIEQVLAAARTAGCDAIHPG
YGFLAENAQFAARCAEQDITFVGPTPEMLTEFGDKARARSLARDCGVPTPQGLFEPSTLEQAEAFLASLEPGAAVILKAV
AGGGGRGIRVVRTPKELPKAFERCSSEAKAAFGQGDLYVERFLPRARHLEVQIIGDGQGGVTHLWERECTLQRRHQKIVE
IAPSPDLPEALREALLDASVRLATAVGYRGLGTFEFLVWDSPAKGGLDFAFIEANPRIQVEHTVTEEVTGVDLVQAQLRV
AGGASLASLGLTQDRIAPPRGHAIQLRVNMERMTPDGAVLPSGGQLTAFDPPSGPGMRTDTFGYAGYRTSPNFDSLLAKV
IVHSPEPDFAAALRRGRRALREFRIGGVPTNLEFLHALISRPEVAANDIYTTFIDDHVRELAAAAEAHVGGLFFAQAAES
ESAPETAADLGAAAPAGMPVSAPLQGTIVALSVKVGDEVPAGGQVAVIEAMKMEHVVRAPCSGVISGLNVTPAETVFEGH
PLLWIEAGEVQVEAAAAQAEPDPDHVRADLAAVLERHALTRDEARPDAVAKRRRRNQRTARENVAAVCDPDTFVEYGPLV
VAAQRGRRSLDELIRTTPADGLVAGFGTVNGSLFGANARCLVLAYDATVLAGTQGREGHRKDQRLFELAERLRTPVIFFA
EGGGGRPGDTERTGEGLSFHYFARLSGKVPLVGVTAGYCFAGNTAFLGCCHVIIATRNANIGMGGPAMVEGGGLGVFSAD
EIGPATMHYARGAVDVLVEDEVEAAAAAKRYLSYFQGDVAPGPCADQRRLRHLVPEDRRRAYDIRPVIETLVDEGSMFEL
RGGWGHGVVTALARIEGKAVGIVANNPMHLAGAIDAEAGDKGARFLQLCDNFGLPVVHLCDTPGIMVGPEAEKTALIRRA
CNLLVAGANLRVPSCTIIVRKFYGLGMIAMMGGAFKAPIFTVAWPTGEYGAMGLEGAVRLAYRKELEAIEDPAERKAVYD
QRVEEMYQEGKALQKASSYDFDDVIDPADSRKWIVHALQCAQHTGEPPGAHPFIHTW

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotin carboxylation domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=461, Percent_Identity=46.6377440347072, Blast_Score=359, Evalue=8e-99,
Organism=Homo sapiens, GI106049295, Length=461, Percent_Identity=46.6377440347072, Blast_Score=359, Evalue=8e-99,
Organism=Homo sapiens, GI106049292, Length=461, Percent_Identity=46.6377440347072, Blast_Score=359, Evalue=8e-99,
Organism=Homo sapiens, GI116805327, Length=468, Percent_Identity=39.5299145299145, Blast_Score=332, Evalue=1e-90,
Organism=Homo sapiens, GI295821183, Length=458, Percent_Identity=38.8646288209607, Blast_Score=269, Evalue=9e-72,
Organism=Homo sapiens, GI65506442, Length=458, Percent_Identity=38.8646288209607, Blast_Score=269, Evalue=1e-71,
Organism=Homo sapiens, GI189095269, Length=458, Percent_Identity=38.8646288209607, Blast_Score=269, Evalue=1e-71,
Organism=Homo sapiens, GI38679974, Length=522, Percent_Identity=28.735632183908, Blast_Score=176, Evalue=9e-44,
Organism=Homo sapiens, GI38679971, Length=522, Percent_Identity=28.735632183908, Blast_Score=176, Evalue=1e-43,
Organism=Homo sapiens, GI38679977, Length=522, Percent_Identity=28.735632183908, Blast_Score=176, Evalue=1e-43,
Organism=Homo sapiens, GI38679967, Length=522, Percent_Identity=28.735632183908, Blast_Score=176, Evalue=1e-43,
Organism=Homo sapiens, GI38679960, Length=522, Percent_Identity=28.735632183908, Blast_Score=176, Evalue=1e-43,
Organism=Homo sapiens, GI134142062, Length=528, Percent_Identity=27.6515151515151, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI119943100, Length=477, Percent_Identity=27.0440251572327, Blast_Score=163, Evalue=8e-40,
Organism=Homo sapiens, GI295821216, Length=491, Percent_Identity=26.2729124236253, Blast_Score=157, Evalue=6e-38,
Organism=Homo sapiens, GI11545863, Length=414, Percent_Identity=29.7101449275362, Blast_Score=144, Evalue=4e-34,
Organism=Escherichia coli, GI1789654, Length=434, Percent_Identity=42.1658986175115, Blast_Score=301, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI17562816, Length=460, Percent_Identity=47.6086956521739, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI71987519, Length=466, Percent_Identity=42.7038626609442, Blast_Score=342, Evalue=6e-94,
Organism=Caenorhabditis elegans, GI17567343, Length=453, Percent_Identity=37.0860927152318, Blast_Score=263, Evalue=4e-70,
Organism=Caenorhabditis elegans, GI25147359, Length=506, Percent_Identity=28.6561264822134, Blast_Score=178, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI25147362, Length=506, Percent_Identity=28.6561264822134, Blast_Score=178, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71997168, Length=429, Percent_Identity=27.7389277389277, Blast_Score=165, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71997163, Length=429, Percent_Identity=27.7389277389277, Blast_Score=165, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI133931226, Length=500, Percent_Identity=27.4, Blast_Score=162, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17552936, Length=495, Percent_Identity=28.0808080808081, Blast_Score=161, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6319695, Length=460, Percent_Identity=46.0869565217391, Blast_Score=359, Evalue=1e-99,
Organism=Saccharomyces cerevisiae, GI6321376, Length=460, Percent_Identity=47.1739130434783, Blast_Score=349, Evalue=1e-96,
Organism=Saccharomyces cerevisiae, GI6319685, Length=460, Percent_Identity=37.1739130434783, Blast_Score=286, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6324343, Length=523, Percent_Identity=26.9598470363289, Blast_Score=158, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6323863, Length=481, Percent_Identity=27.6507276507277, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI281363050, Length=460, Percent_Identity=47.6086956521739, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24652224, Length=460, Percent_Identity=47.6086956521739, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24652222, Length=460, Percent_Identity=47.6086956521739, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24652220, Length=460, Percent_Identity=47.6086956521739, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24652218, Length=460, Percent_Identity=47.6086956521739, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24652212, Length=460, Percent_Identity=47.6086956521739, Blast_Score=378, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24652210, Length=460, Percent_Identity=47.6086956521739, Blast_Score=378, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24652214, Length=460, Percent_Identity=47.6086956521739, Blast_Score=378, Evalue=1e-104,
Organism=Drosophila melanogaster, GI19921944, Length=460, Percent_Identity=47.6086956521739, Blast_Score=378, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24652216, Length=460, Percent_Identity=47.6086956521739, Blast_Score=378, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24651757, Length=462, Percent_Identity=38.7445887445887, Blast_Score=306, Evalue=7e-83,
Organism=Drosophila melanogaster, GI24651759, Length=424, Percent_Identity=37.5, Blast_Score=268, Evalue=2e-71,
Organism=Drosophila melanogaster, GI161076409, Length=561, Percent_Identity=28.1639928698752, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24586458, Length=561, Percent_Identity=28.1639928698752, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI161076407, Length=561, Percent_Identity=28.1639928698752, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24586460, Length=561, Percent_Identity=28.1639928698752, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24586065, Length=513, Percent_Identity=27.2904483430799, Blast_Score=146, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004549
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR011054 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2 [H]

EC number: =6.3.4.14; =6.4.1.2 [H]

Molecular weight: Translated: 117132; Mature: 117001

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS50975 ATP_GRASP ; PS00867 CPSASE_2 ; PS50979 BC ; PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIQRLLIANRGEIAIRIARAADELGMATVAICSEDDRGSLHTAKADDLHVLSGVGAKAY
CCCHHHHHCCCCCEEEEEEHHHHHCCCEEEEEECCCCCCCEEECCCCCEEEECCCCCCEE
LDIEQVLAAARTAGCDAIHPGYGFLAENAQFAARCAEQDITFVGPTPEMLTEFGDKARAR
ECHHHHHHHHHHCCCCCCCCCCCCHHCCHHHHHHHHHCCCEEECCCHHHHHHHCHHHHHH
SLARDCGVPTPQGLFEPSTLEQAEAFLASLEPGAAVILKAVAGGGGRGIRVVRTPKELPK
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEECHHHHHH
AFERCSSEAKAAFGQGDLYVERFLPRARHLEVQIIGDGQGGVTHLWERECTLQRRHQKIV
HHHHHCHHHHHHCCCCCHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHE
EIAPSPDLPEALREALLDASVRLATAVGYRGLGTFEFLVWDSPAKGGLDFAFIEANPRIQ
EECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEECCCCEE
VEHTVTEEVTGVDLVQAQLRVAGGASLASLGLTQDRIAPPRGHAIQLRVNMERMTPDGAV
EEEEHHHHHCCHHHHHHHHHHCCCCCHHHCCCCHHHCCCCCCCEEEEEEEHHHCCCCCCE
LPSGGQLTAFDPPSGPGMRTDTFGYAGYRTSPNFDSLLAKVIVHSPEPDFAAALRRGRRA
ECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
LREFRIGGVPTNLEFLHALISRPEVAANDIYTTFIDDHVRELAAAAEAHVGGLFFAQAAE
HHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
SESAPETAADLGAAAPAGMPVSAPLQGTIVALSVKVGDEVPAGGQVAVIEAMKMEHVVRA
CCCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCEEEHHHHHHHHHHHC
PCSGVISGLNVTPAETVFEGHPLLWIEAGEVQVEAAAAQAEPDPDHVRADLAAVLERHAL
CHHHHHCCCCCCCHHHHHCCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHC
TRDEARPDAVAKRRRRNQRTARENVAAVCDPDTFVEYGPLVVAAQRGRRSLDELIRTTPA
CCCCCCHHHHHHHHHHHHHHHHHCCEEEECCHHHHHCCCEEEEEHHHHHHHHHHHHCCCC
DGLVAGFGTVNGSLFGANARCLVLAYDATVLAGTQGREGHRKDQRLFELAERLRTPVIFF
CCEEEECCCCCCEEECCCCEEEEEEECCEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEE
AEGGGGRPGDTERTGEGLSFHYFARLSGKVPLVGVTAGYCFAGNTAFLGCCHVIIATRNA
ECCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCEEECCCCHHHHEEEEEEEECCC
NIGMGGPAMVEGGGLGVFSADEIGPATMHYARGAVDVLVEDEVEAAAAAKRYLSYFQGDV
CCCCCCCCEEECCCEEEECCCCCCCHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCC
APGPCADQRRLRHLVPEDRRRAYDIRPVIETLVDEGSMFELRGGWGHGVVTALARIEGKA
CCCCCCHHHHHHHCCCHHHHHCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCE
VGIVANNPMHLAGAIDAEAGDKGARFLQLCDNFGLPVVHLCDTPGIMVGPEAEKTALIRR
EEEEECCCEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEECCCCCEEECCCHHHHHHHHH
ACNLLVAGANLRVPSCTIIVRKFYGLGMIAMMGGAFKAPIFTVAWPTGEYGAMGLEGAVR
HHHHEEECCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHH
LAYRKELEAIEDPAERKAVYDQRVEEMYQEGKALQKASSYDFDDVIDPADSRKWIVHALQ
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHH
CAQHTGEPPGAHPFIHTW
HHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
AIQRLLIANRGEIAIRIARAADELGMATVAICSEDDRGSLHTAKADDLHVLSGVGAKAY
CCHHHHHCCCCCEEEEEEHHHHHCCCEEEEEECCCCCCCEEECCCCCEEEECCCCCCEE
LDIEQVLAAARTAGCDAIHPGYGFLAENAQFAARCAEQDITFVGPTPEMLTEFGDKARAR
ECHHHHHHHHHHCCCCCCCCCCCCHHCCHHHHHHHHHCCCEEECCCHHHHHHHCHHHHHH
SLARDCGVPTPQGLFEPSTLEQAEAFLASLEPGAAVILKAVAGGGGRGIRVVRTPKELPK
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEECHHHHHH
AFERCSSEAKAAFGQGDLYVERFLPRARHLEVQIIGDGQGGVTHLWERECTLQRRHQKIV
HHHHHCHHHHHHCCCCCHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHE
EIAPSPDLPEALREALLDASVRLATAVGYRGLGTFEFLVWDSPAKGGLDFAFIEANPRIQ
EECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEECCCCEE
VEHTVTEEVTGVDLVQAQLRVAGGASLASLGLTQDRIAPPRGHAIQLRVNMERMTPDGAV
EEEEHHHHHCCHHHHHHHHHHCCCCCHHHCCCCHHHCCCCCCCEEEEEEEHHHCCCCCCE
LPSGGQLTAFDPPSGPGMRTDTFGYAGYRTSPNFDSLLAKVIVHSPEPDFAAALRRGRRA
ECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
LREFRIGGVPTNLEFLHALISRPEVAANDIYTTFIDDHVRELAAAAEAHVGGLFFAQAAE
HHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
SESAPETAADLGAAAPAGMPVSAPLQGTIVALSVKVGDEVPAGGQVAVIEAMKMEHVVRA
CCCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCEEEHHHHHHHHHHHC
PCSGVISGLNVTPAETVFEGHPLLWIEAGEVQVEAAAAQAEPDPDHVRADLAAVLERHAL
CHHHHHCCCCCCCHHHHHCCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHC
TRDEARPDAVAKRRRRNQRTARENVAAVCDPDTFVEYGPLVVAAQRGRRSLDELIRTTPA
CCCCCCHHHHHHHHHHHHHHHHHCCEEEECCHHHHHCCCEEEEEHHHHHHHHHHHHCCCC
DGLVAGFGTVNGSLFGANARCLVLAYDATVLAGTQGREGHRKDQRLFELAERLRTPVIFF
CCEEEECCCCCCEEECCCCEEEEEEECCEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEE
AEGGGGRPGDTERTGEGLSFHYFARLSGKVPLVGVTAGYCFAGNTAFLGCCHVIIATRNA
ECCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCEEECCCCHHHHEEEEEEEECCC
NIGMGGPAMVEGGGLGVFSADEIGPATMHYARGAVDVLVEDEVEAAAAAKRYLSYFQGDV
CCCCCCCCEEECCCEEEECCCCCCCHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCC
APGPCADQRRLRHLVPEDRRRAYDIRPVIETLVDEGSMFELRGGWGHGVVTALARIEGKA
CCCCCCHHHHHHHCCCHHHHHCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCE
VGIVANNPMHLAGAIDAEAGDKGARFLQLCDNFGLPVVHLCDTPGIMVGPEAEKTALIRR
EEEEECCCEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEECCCCCEEECCCHHHHHHHHH
ACNLLVAGANLRVPSCTIIVRKFYGLGMIAMMGGAFKAPIFTVAWPTGEYGAMGLEGAVR
HHHHEEECCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHH
LAYRKELEAIEDPAERKAVYDQRVEEMYQEGKALQKASSYDFDDVIDPADSRKWIVHALQ
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHH
CAQHTGEPPGAHPFIHTW
HHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8102363; 11759840 [H]