Click here to switch to the map view.

The map label for this gene is fadB1 [H]

Identifier: 197105990

GI number: 197105990

Start: 2903480

End: 2904256

Strand: Reverse

Name: fadB1 [H]

Synonym: PHZ_c2529

Alternate gene names: 197105990

Gene position: 2904256-2903480 (Counterclockwise)

Preceding gene: 197105991

Following gene: 197105989

Centisome position: 72.67

GC content: 70.66

Gene sequence:

>777_bases
ATGAGCTACGAGACTCTGCGCTACGAGGAGCGCGGCCGTGTCGCGGTGATCACCTACGATCGCCAGGAGCGCCGCAACGC
GTGGAACCCGCCGATGTACCGGGAGGCCGTCGCCGCCATCGAGCGGGCCAACGCCTCGGCGGACGTGGGCGCGATCGTGA
TCACCCACGACGGACCGGTGTTCTGCGCTGGCACCGACTTCAAGGCCGAGCCCGAGCCGCCGGATCCGCAGACCGGCCGC
CGGCCCAACGTGGCGACGCTGTCCATGGCGCAGGACGCGAGCTGGCTGCATCTCCTGGCCCGGTCCAAGCCGACGATCGG
GGCGATCCGCGGCGCCGCGATCGGCCTGGGCGTGACCCAGATCCTGCCCTTCGACATCCGCATCGGAGGGGCGTCCTCGA
CCTACTCGTTCCCGTTCCTGTCGCTGGGGCTGATGCCCGAGCTGGGCTGCACGGCGCTGCTTCCGCGGCTGGTCGGCTAC
GGCCACGCCGTGGACATCTGCCTCTCCTCGGCCAAGCTCAGCGCGCAGGAGGCCCTCGACATCGGCCTGATCACCCGAGT
GGCGGGGGACGACGACGTCGTGGCGGAGGCCGTCGCTCTGGGCGAGAAGCTCGCCGCGGCACCGGCCCTGCAGATGCAGC
TCACCCGCGAGCTGCTGCGGGAGAACTCCGGCGAGCATGACGCTAACGTCGTCCTCGCGCGAGAGACCGAGGCCTTCGTG
ACCATGTTCCGCGCGGCCAAGGAAGCCAAGAAGAAGGCCGCCGCGGAAGGCGCCTGA

Upstream 100 bases:

>100_bases
CGACCGCATGTTCGCCCACGAGGTCTCGCGCCACGCGCAGTCCTAGTCTGACGAACGCCGGGCGGGCCCTTGGGCCGGCC
CGCTACGCTCGGGAGCAGCC

Downstream 100 bases:

>100_bases
CGGCGTGGATCGGTCGGCGCCGCCCGTGGCCCGGCAGGGAGGATAGGCAGGATGCCCGCGCCGTTGTCGAACGTACGTGT
GCTGGAGCTCGGTCGCGTCT

Product: enoyl-CoA hydratase/carnithine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSYETLRYEERGRVAVITYDRQERRNAWNPPMYREAVAAIERANASADVGAIVITHDGPVFCAGTDFKAEPEPPDPQTGR
RPNVATLSMAQDASWLHLLARSKPTIGAIRGAAIGLGVTQILPFDIRIGGASSTYSFPFLSLGLMPELGCTALLPRLVGY
GHAVDICLSSAKLSAQEALDIGLITRVAGDDDVVAEAVALGEKLAAAPALQMQLTRELLRENSGEHDANVVLARETEAFV
TMFRAAKEAKKKAAAEGA

Sequences:

>Translated_258_residues
MSYETLRYEERGRVAVITYDRQERRNAWNPPMYREAVAAIERANASADVGAIVITHDGPVFCAGTDFKAEPEPPDPQTGR
RPNVATLSMAQDASWLHLLARSKPTIGAIRGAAIGLGVTQILPFDIRIGGASSTYSFPFLSLGLMPELGCTALLPRLVGY
GHAVDICLSSAKLSAQEALDIGLITRVAGDDDVVAEAVALGEKLAAAPALQMQLTRELLRENSGEHDANVVLARETEAFV
TMFRAAKEAKKKAAAEGA
>Mature_257_residues
SYETLRYEERGRVAVITYDRQERRNAWNPPMYREAVAAIERANASADVGAIVITHDGPVFCAGTDFKAEPEPPDPQTGRR
PNVATLSMAQDASWLHLLARSKPTIGAIRGAAIGLGVTQILPFDIRIGGASSTYSFPFLSLGLMPELGCTALLPRLVGYG
HAVDICLSSAKLSAQEALDIGLITRVAGDDDVVAEAVALGEKLAAAPALQMQLTRELLRENSGEHDANVVLARETEAFVT
MFRAAKEAKKKAAAEGA

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=226, Percent_Identity=28.3185840707965, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI260274832, Length=225, Percent_Identity=27.1111111111111, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI45643119, Length=225, Percent_Identity=27.1111111111111, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI260275230, Length=225, Percent_Identity=27.1111111111111, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI70995211, Length=204, Percent_Identity=28.921568627451, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI221307494, Length=216, Percent_Identity=26.8518518518519, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI221136756, Length=216, Percent_Identity=26.8518518518519, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI221136753, Length=216, Percent_Identity=26.8518518518519, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4757968, Length=218, Percent_Identity=26.605504587156, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI49355787, Length=218, Percent_Identity=26.605504587156, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI25453481, Length=218, Percent_Identity=26.1467889908257, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI51538573, Length=218, Percent_Identity=26.1467889908257, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI4757966, Length=218, Percent_Identity=26.1467889908257, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI51538581, Length=218, Percent_Identity=26.1467889908257, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI68989263, Length=183, Percent_Identity=30.0546448087432, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787659, Length=230, Percent_Identity=30.8695652173913, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1787660, Length=226, Percent_Identity=31.4159292035398, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI221142681, Length=223, Percent_Identity=25.1121076233184, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17554946, Length=208, Percent_Identity=31.25, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17535521, Length=218, Percent_Identity=29.8165137614679, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17560910, Length=214, Percent_Identity=27.5700934579439, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI25145438, Length=234, Percent_Identity=30.3418803418803, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17549921, Length=240, Percent_Identity=25.4166666666667, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17536985, Length=236, Percent_Identity=25, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17558304, Length=192, Percent_Identity=28.6458333333333, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17534483, Length=243, Percent_Identity=23.8683127572016, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508951, Length=190, Percent_Identity=28.9473684210526, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25144276, Length=190, Percent_Identity=28.9473684210526, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508953, Length=190, Percent_Identity=28.9473684210526, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20129971, Length=221, Percent_Identity=30.7692307692308, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24653477, Length=221, Percent_Identity=30.7692307692308, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24654903, Length=185, Percent_Identity=28.1081081081081, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27588; Mature: 27457

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYETLRYEERGRVAVITYDRQERRNAWNPPMYREAVAAIERANASADVGAIVITHDGPV
CCCCCCEECCCCCEEEEEECHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCE
FCAGTDFKAEPEPPDPQTGRRPNVATLSMAQDASWLHLLARSKPTIGAIRGAAIGLGVTQ
EEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHCCHHH
ILPFDIRIGGASSTYSFPFLSLGLMPELGCTALLPRLVGYGHAVDICLSSAKLSAQEALD
EEEEEEEECCCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
IGLITRVAGDDDVVAEAVALGEKLAAAPALQMQLTRELLRENSGEHDANVVLARETEAFV
HHHEEEECCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHH
TMFRAAKEAKKKAAAEGA
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SYETLRYEERGRVAVITYDRQERRNAWNPPMYREAVAAIERANASADVGAIVITHDGPV
CCCCCEECCCCCEEEEEECHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCE
FCAGTDFKAEPEPPDPQTGRRPNVATLSMAQDASWLHLLARSKPTIGAIRGAAIGLGVTQ
EEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHCCHHH
ILPFDIRIGGASSTYSFPFLSLGLMPELGCTALLPRLVGYGHAVDICLSSAKLSAQEALD
EEEEEEEECCCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
IGLITRVAGDDDVVAEAVALGEKLAAAPALQMQLTRELLRENSGEHDANVVLARETEAFV
HHHEEEECCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHH
TMFRAAKEAKKKAAAEGA
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]