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The map label for this gene is srfAB [H]

Identifier: 197105980

GI number: 197105980

Start: 2891079

End: 2892953

Strand: Reverse

Name: srfAB [H]

Synonym: PHZ_c2519

Alternate gene names: 197105980

Gene position: 2892953-2891079 (Counterclockwise)

Preceding gene: 197105981

Following gene: 197105979

Centisome position: 72.39

GC content: 69.6

Gene sequence:

>1875_bases
ATGCCCAACCGCCTGGACGCGCCCGCCTACCGTCCCCTGCCGATCCGCAAGCCCAACGTAACCTGCCAGGCGCGCCCGGA
CGGCAGCTATATCCTCGAGCAGAACTACGAGATGCCCGAGCCCTGGCGCTCCATCCCGCACCTCTTCCAGGCCCGGGCCC
AGGCGTTTCCGGACCGTCCCATGGTCGCCAAGCGCGAGCCGCTCGCCGGCGGCGGGTGGGGCGAGTGGCGCAAGATCACG
TTCGGCGAGGCGCTGACGCAATCCCGCGCGCTCGCCCAGGCGCTCCTCGACCTCGGGGCCGGGCAGGATGCGGGCGTCAT
GGTCCTGTCGGGCCCTTCCATCGAACACGCCGTGATCTCCCTGGCCGCCCAGATGGCCCGCGCGCCGTTCGCGCCCGTCT
CGTCCGGCTATTCGCTCGTCGCCGGGGACTTCTCCCGTCTGCAGCACGTGTTCGCCACCTGCCGGCCGAAGATCGTCTTC
GCCGACGACGGGCCGGCGTTCTCGCGCGCGCTGAAGGCCCTGCCGCTCGACGGCGTGAAGGTGATCACCGTCACGCCGAG
CGACGTCCCGAGCCTCAGCTACGCCGAGCTGATCGCGACGCCGCCGACTGCGGCCGTGGATGCCTCGATCGCCGCAATCA
CGCCCGACACCTTCGCCAAGACCATCTTCACGTCGGGGTCCACTGGGCGGCCGAAGGGGGTGATCCAGACCCAGCGCATG
CTGACGGCGATCATCGCCCAGCACGATGCGCTCTACATCCGCGACGAAGAGGACGAGGCGCCGGGCGCCTACCTGTCGTG
GCTGCCCTGGAGCCACGTCGGCGGGACAAACGTCCTGTTCGGCGACGTGATCAACGACGGCGCCTGTCTCTACATCGACG
AGGGTCGCCCGGTCGCCGGGCAGTTCGACGAGACGCTCCGGAACCTGCGGGAGATCCAGCCCCGCGAGTACGGGTCCACG
CCGATCTTCTTCTCGCATCTGGTGGCGGCGATGGAGGCGGATGCCGCCCTGCGCGACCACTTCTTCGGTCGCCTGCGGTA
TCTCAACTACTCGACGGCGGGCCTGTCGCAGGACCTGTTCGAGCGCCTACAGGCGCTGTCCATCGCCGCGACCGGCCAAC
GCATCCCGATCAGCACCAAGTATGGCTCGACGGAGACCCAGGGGGTCACCATCGTTTCCGAGCCGCTCGACTACACCGGT
CCCATCGGACTTCCGTTCCCGGGCATCACGGTCAAGCTTGCGCCTGTCGGCGATAAGCTCGAGATCCGGGCGAAGGGCGA
CACCGTGACGCCGGGCTACTTGGGCGACCCGGAGGCCACCGCCAAGGCGTTCGACGAGGAGGGCTTCTACCGCACCGGCG
ACGCCGCCCGCTTCGTCGATCCCGAGAATCCCAGCCGCGGCCTGATCTTCGACGGCCGGGTGACCGAGAACTTCAAGCTG
GCCACCGGCACGTGGGTGTCGGTGGGGCCGCTGCGCCTGGCGCTAATCGAGGCCCTCTCGCCGGTGCTCGAGGACGCCGT
CATCGCCGGCGAGAACCGCGACGAGATCTGTGTCCTGGCCTGGGTGCGCCGCGTGGAAGCCGCGGCAGTGGCGGGGCTCG
GCAGGGACGCTTCGCTCGCCGAGATCTGCCGCGCCCCCAAGCTGTCGGCGTTCATCCGCGAACGGCTGGCGCAGCACAAC
GAAACGGCGGGCGGCTCATCGAGACGCGTCGCGCGCCTCCTCCTGCTGGATGCGCCGGCGACCGGCGATGAGATCGCCGA
GAAGGGCTACATCAACCAGCGCGCGGTCCTGCGGAACCGCGCTGCTCAGGTGGAAGCGCTCTACGCCGCCGAGCGTGGGC
CGGACCTGATCATCGCACCGGAATTGACGGCCTAG

Upstream 100 bases:

>100_bases
GTGAAGGTGTCCTACGCCTGGTAGACTGATCCTCCCCCCTGGGCGCGGCGGTTCCGGCCGTCGCGCCCGTCTTCGTTGCT
GACATACGGTTCGCCCGATC

Downstream 100 bases:

>100_bases
CCGGCCGCAGGAGGACCCATGGCGCTCAAGACCCGTTTCACCGAGACCTTCGGGGTCGAGCACCCCATCGTGCAGGGGGG
CATGCAGTGGGTCGGCCGGG

Product: feruloyl-CoA synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 624; Mature: 623

Protein sequence:

>624_residues
MPNRLDAPAYRPLPIRKPNVTCQARPDGSYILEQNYEMPEPWRSIPHLFQARAQAFPDRPMVAKREPLAGGGWGEWRKIT
FGEALTQSRALAQALLDLGAGQDAGVMVLSGPSIEHAVISLAAQMARAPFAPVSSGYSLVAGDFSRLQHVFATCRPKIVF
ADDGPAFSRALKALPLDGVKVITVTPSDVPSLSYAELIATPPTAAVDASIAAITPDTFAKTIFTSGSTGRPKGVIQTQRM
LTAIIAQHDALYIRDEEDEAPGAYLSWLPWSHVGGTNVLFGDVINDGACLYIDEGRPVAGQFDETLRNLREIQPREYGST
PIFFSHLVAAMEADAALRDHFFGRLRYLNYSTAGLSQDLFERLQALSIAATGQRIPISTKYGSTETQGVTIVSEPLDYTG
PIGLPFPGITVKLAPVGDKLEIRAKGDTVTPGYLGDPEATAKAFDEEGFYRTGDAARFVDPENPSRGLIFDGRVTENFKL
ATGTWVSVGPLRLALIEALSPVLEDAVIAGENRDEICVLAWVRRVEAAAVAGLGRDASLAEICRAPKLSAFIRERLAQHN
ETAGGSSRRVARLLLLDAPATGDEIAEKGYINQRAVLRNRAAQVEALYAAERGPDLIIAPELTA

Sequences:

>Translated_624_residues
MPNRLDAPAYRPLPIRKPNVTCQARPDGSYILEQNYEMPEPWRSIPHLFQARAQAFPDRPMVAKREPLAGGGWGEWRKIT
FGEALTQSRALAQALLDLGAGQDAGVMVLSGPSIEHAVISLAAQMARAPFAPVSSGYSLVAGDFSRLQHVFATCRPKIVF
ADDGPAFSRALKALPLDGVKVITVTPSDVPSLSYAELIATPPTAAVDASIAAITPDTFAKTIFTSGSTGRPKGVIQTQRM
LTAIIAQHDALYIRDEEDEAPGAYLSWLPWSHVGGTNVLFGDVINDGACLYIDEGRPVAGQFDETLRNLREIQPREYGST
PIFFSHLVAAMEADAALRDHFFGRLRYLNYSTAGLSQDLFERLQALSIAATGQRIPISTKYGSTETQGVTIVSEPLDYTG
PIGLPFPGITVKLAPVGDKLEIRAKGDTVTPGYLGDPEATAKAFDEEGFYRTGDAARFVDPENPSRGLIFDGRVTENFKL
ATGTWVSVGPLRLALIEALSPVLEDAVIAGENRDEICVLAWVRRVEAAAVAGLGRDASLAEICRAPKLSAFIRERLAQHN
ETAGGSSRRVARLLLLDAPATGDEIAEKGYINQRAVLRNRAAQVEALYAAERGPDLIIAPELTA
>Mature_623_residues
PNRLDAPAYRPLPIRKPNVTCQARPDGSYILEQNYEMPEPWRSIPHLFQARAQAFPDRPMVAKREPLAGGGWGEWRKITF
GEALTQSRALAQALLDLGAGQDAGVMVLSGPSIEHAVISLAAQMARAPFAPVSSGYSLVAGDFSRLQHVFATCRPKIVFA
DDGPAFSRALKALPLDGVKVITVTPSDVPSLSYAELIATPPTAAVDASIAAITPDTFAKTIFTSGSTGRPKGVIQTQRML
TAIIAQHDALYIRDEEDEAPGAYLSWLPWSHVGGTNVLFGDVINDGACLYIDEGRPVAGQFDETLRNLREIQPREYGSTP
IFFSHLVAAMEADAALRDHFFGRLRYLNYSTAGLSQDLFERLQALSIAATGQRIPISTKYGSTETQGVTIVSEPLDYTGP
IGLPFPGITVKLAPVGDKLEIRAKGDTVTPGYLGDPEATAKAFDEEGFYRTGDAARFVDPENPSRGLIFDGRVTENFKLA
TGTWVSVGPLRLALIEALSPVLEDAVIAGENRDEICVLAWVRRVEAAAVAGLGRDASLAEICRAPKLSAFIRERLAQHNE
TAGGSSRRVARLLLLDAPATGDEIAEKGYINQRAVLRNRAAQVEALYAAERGPDLIIAPELTA

Specific function: This protein is a multifunctional enzyme able to activate and polymerize the amino acids Leu, Glu, Asp and Val. Activation sites for these AA consist of individual domains [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 acyl carrier domains [H]

Homologues:

Organism=Caenorhabditis elegans, GI17556552, Length=393, Percent_Identity=26.2086513994911, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17564090, Length=450, Percent_Identity=24.2222222222222, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356947, Length=401, Percent_Identity=24.6882793017456, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: NA

Molecular weight: Translated: 67284; Mature: 67153

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNRLDAPAYRPLPIRKPNVTCQARPDGSYILEQNYEMPEPWRSIPHLFQARAQAFPDRP
CCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCC
MVAKREPLAGGGWGEWRKITFGEALTQSRALAQALLDLGAGQDAGVMVLSGPSIEHAVIS
CCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHH
LAAQMARAPFAPVSSGYSLVAGDFSRLQHVFATCRPKIVFADDGPAFSRALKALPLDGVK
HHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCEE
VITVTPSDVPSLSYAELIATPPTAAVDASIAAITPDTFAKTIFTSGSTGRPKGVIQTQRM
EEEECCCCCCCCCHHHHHCCCCCHHHCCEEEEECCHHHHHHHCCCCCCCCCCCHHHHHHH
LTAIIAQHDALYIRDEEDEAPGAYLSWLPWSHVGGTNVLFGDVINDGACLYIDEGRPVAG
HHHHHHCCCEEEEECCCCCCCCCEEECCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCC
QFDETLRNLREIQPREYGSTPIFFSHLVAAMEADAALRDHFFGRLRYLNYSTAGLSQDLF
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHH
ERLQALSIAATGQRIPISTKYGSTETQGVTIVSEPLDYTGPIGLPFPGITVKLAPVGDKL
HHHHHHHHEECCCCCCEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCEE
EIRAKGDTVTPGYLGDPEATAKAFDEEGFYRTGDAARFVDPENPSRGLIFDGRVTENFKL
EEEECCCCCCCCCCCCCHHHHHHHCCCCCEECCCCEEECCCCCCCCCEEECCEECCCEEE
ATGTWVSVGPLRLALIEALSPVLEDAVIAGENRDEICVLAWVRRVEAAAVAGLGRDASLA
ECCCEEEECHHHHHHHHHHHHHHHHHEECCCCCCCEEHHHHHHHHHHHHHHCCCCCCHHH
EICRAPKLSAFIRERLAQHNETAGGSSRRVARLLLLDAPATGDEIAEKGYINQRAVLRNR
HHHCCCCHHHHHHHHHHHCCCCCCCCHHHEEEEEEEECCCCCHHHHHCCCCCHHHHHHHH
AAQVEALYAAERGPDLIIAPELTA
HHHHHHHHHHCCCCCEEECCCCCC
>Mature Secondary Structure 
PNRLDAPAYRPLPIRKPNVTCQARPDGSYILEQNYEMPEPWRSIPHLFQARAQAFPDRP
CCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCC
MVAKREPLAGGGWGEWRKITFGEALTQSRALAQALLDLGAGQDAGVMVLSGPSIEHAVIS
CCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHH
LAAQMARAPFAPVSSGYSLVAGDFSRLQHVFATCRPKIVFADDGPAFSRALKALPLDGVK
HHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCEE
VITVTPSDVPSLSYAELIATPPTAAVDASIAAITPDTFAKTIFTSGSTGRPKGVIQTQRM
EEEECCCCCCCCCHHHHHCCCCCHHHCCEEEEECCHHHHHHHCCCCCCCCCCCHHHHHHH
LTAIIAQHDALYIRDEEDEAPGAYLSWLPWSHVGGTNVLFGDVINDGACLYIDEGRPVAG
HHHHHHCCCEEEEECCCCCCCCCEEECCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCC
QFDETLRNLREIQPREYGSTPIFFSHLVAAMEADAALRDHFFGRLRYLNYSTAGLSQDLF
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHH
ERLQALSIAATGQRIPISTKYGSTETQGVTIVSEPLDYTGPIGLPFPGITVKLAPVGDKL
HHHHHHHHEECCCCCCEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCEE
EIRAKGDTVTPGYLGDPEATAKAFDEEGFYRTGDAARFVDPENPSRGLIFDGRVTENFKL
EEEECCCCCCCCCCCCCHHHHHHHCCCCCEECCCCEEECCCCCCCCCEEECCEECCCEEE
ATGTWVSVGPLRLALIEALSPVLEDAVIAGENRDEICVLAWVRRVEAAAVAGLGRDASLA
ECCCEEEECHHHHHHHHHHHHHHHHHEECCCCCCCEEHHHHHHHHHHHHHHCCCCCCHHH
EICRAPKLSAFIRERLAQHNETAGGSSRRVARLLLLDAPATGDEIAEKGYINQRAVLRNR
HHHCCCCHHHHHHHHHHHCCCCCCCCHHHEEEEEEEECCCCCHHHHHCCCCCHHHHHHHH
AAQVEALYAAERGPDLIIAPELTA
HHHHHHHHHHCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8441623; 8355609; 8969502; 9384377; 1601288 [H]