Click here to switch to the map view.

The map label for this gene is exuT [H]

Identifier: 197105925

GI number: 197105925

Start: 2819834

End: 2821108

Strand: Reverse

Name: exuT [H]

Synonym: PHZ_c2464

Alternate gene names: 197105925

Gene position: 2821108-2819834 (Counterclockwise)

Preceding gene: 197105926

Following gene: 197105924

Centisome position: 70.59

GC content: 71.29

Gene sequence:

>1275_bases
ATGCGCCGGCTCTGGGCCCTCCGCTGGTGGATCATCGCGCTCGTCATGCTGGGCGCGATGCTCAACTACCTGACGCGCGC
GACCATGGGCGTGGCCGCGCCGACCATGCTGGCCGACCTGTCGATCAGCGAGCGGGAGTACGGCTGGATCACCGGCGCCT
TCCAGGCCGGGATCATGCTCCAGCCGGCGGTGGGCTACGTCCTCGACACCCTCGGCCTGCGCACCGGCCTGGCGATCTTC
GCGGGCGCCTGGTCGGCGATCTCGATCGCCCACGGCTTCGCCAGCACGTGGCCCGCCTTCGCCGCCCTGCGGGGGCTGCT
GGGCTTCGCGGAAGGCTCGGCCAATCCGGCGGGGATGAAGGTGGTCGCCACCTGGTTCCCGGCGCGCGAGCGCGGCTTCG
CGGGCGGGGTCTACAACATCGGCGCCTCGTTCGGGACGATGCTCGCGCCGCCGCTGGTGGCCTGGGCGATCCTGGCCTTC
AACTGGCGCGCGGCCTTCATCATCACCGGCCTCCTGGGCCTCGTCTGGACGGCGCTCTGGTGGTGGGGCTTCCGCACGCC
CGACCAGCATCCGCGCCTGTCGCCGCAGGAGCGGGCTAAGATCCTCGAGGGGCAGGAGCCGGACCTCCATGACGACGGCG
CCCGGCCCTCGATGCTGAAGCTGATGGCCCGCCGGGACTTCTGGGGCATCGCGATCCCCCGCCTGCTCGCCGACCCCACC
TGGGGCACGCTGGCGTTCTGGATCCCGCTCTACCTGGTCCAGACCCGCGGCTTCGACCTGAAGCAGATCGCCATGTTCGC
CTGGCTGCCGTTCCTGGCCGCGGACCTCGGCTGCCTGTTCGGGCCGGCCGTCGTCGAGTTCCTGCAGCGGCGCGGCGTCA
GCCTGATCAACGCCCGGCGCGGCGCCTTCACCCTGGGCGCGCTGATGATGACCGGGATGATGTTCGTCGGCCGGGTAGAG
AGCCCCTATCTCGCCATCGCGCTGCTCTGCCTGGGCGGCTTCGCCCATCAGACGCTGTCGGTCACCGTCATCACCATGGC
CTCCGACCTCTTCAAGCGGAACGAGGTGGCGACCGTGGCCGGCATGGCCGGGACCTTCGGGAACCTCGGCGTGCTGATCT
TCTCGCTGCTGATCGGCGGCCTGGTGGCGACGGTCGGCTACGATCCGTTCTTCCTCGCCCTCGGCCTCCTGGACCTCGTC
GGGGCGGCGGTCCTCTGGACCCTGGTGCGCGACCGGCCGGTGCGGGCTCCGGTCTCGGAGCTGCCGGCGGCATGA

Upstream 100 bases:

>100_bases
CGCTGTTCTTCGTGCGCGCCATGGTCAAGGAGACCCGCGGCCGCGAACTCGAGGAGATGACGGGCTGACGGCCTAGGGCT
GGCTTCCTCGGACCCGCGCC

Downstream 100 bases:

>100_bases
GCGTGCGCAATCCCGTCCTGCGCGGCTTCAACCCCGACCCGTCGATCGTACGGGTGGGCGAGGACTACTACCTCGCCACC
TCGACCTTCGAGTGGTTTCC

Product: hexuronate transporter

Products: galacturonate [Cytoplasm]; Proton [Cytoplasm]; glucuronate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MRRLWALRWWIIALVMLGAMLNYLTRATMGVAAPTMLADLSISEREYGWITGAFQAGIMLQPAVGYVLDTLGLRTGLAIF
AGAWSAISIAHGFASTWPAFAALRGLLGFAEGSANPAGMKVVATWFPARERGFAGGVYNIGASFGTMLAPPLVAWAILAF
NWRAAFIITGLLGLVWTALWWWGFRTPDQHPRLSPQERAKILEGQEPDLHDDGARPSMLKLMARRDFWGIAIPRLLADPT
WGTLAFWIPLYLVQTRGFDLKQIAMFAWLPFLAADLGCLFGPAVVEFLQRRGVSLINARRGAFTLGALMMTGMMFVGRVE
SPYLAIALLCLGGFAHQTLSVTVITMASDLFKRNEVATVAGMAGTFGNLGVLIFSLLIGGLVATVGYDPFFLALGLLDLV
GAAVLWTLVRDRPVRAPVSELPAA

Sequences:

>Translated_424_residues
MRRLWALRWWIIALVMLGAMLNYLTRATMGVAAPTMLADLSISEREYGWITGAFQAGIMLQPAVGYVLDTLGLRTGLAIF
AGAWSAISIAHGFASTWPAFAALRGLLGFAEGSANPAGMKVVATWFPARERGFAGGVYNIGASFGTMLAPPLVAWAILAF
NWRAAFIITGLLGLVWTALWWWGFRTPDQHPRLSPQERAKILEGQEPDLHDDGARPSMLKLMARRDFWGIAIPRLLADPT
WGTLAFWIPLYLVQTRGFDLKQIAMFAWLPFLAADLGCLFGPAVVEFLQRRGVSLINARRGAFTLGALMMTGMMFVGRVE
SPYLAIALLCLGGFAHQTLSVTVITMASDLFKRNEVATVAGMAGTFGNLGVLIFSLLIGGLVATVGYDPFFLALGLLDLV
GAAVLWTLVRDRPVRAPVSELPAA
>Mature_424_residues
MRRLWALRWWIIALVMLGAMLNYLTRATMGVAAPTMLADLSISEREYGWITGAFQAGIMLQPAVGYVLDTLGLRTGLAIF
AGAWSAISIAHGFASTWPAFAALRGLLGFAEGSANPAGMKVVATWFPARERGFAGGVYNIGASFGTMLAPPLVAWAILAF
NWRAAFIITGLLGLVWTALWWWGFRTPDQHPRLSPQERAKILEGQEPDLHDDGARPSMLKLMARRDFWGIAIPRLLADPT
WGTLAFWIPLYLVQTRGFDLKQIAMFAWLPFLAADLGCLFGPAVVEFLQRRGVSLINARRGAFTLGALMMTGMMFVGRVE
SPYLAIALLCLGGFAHQTLSVTVITMASDLFKRNEVATVAGMAGTFGNLGVLIFSLLIGGLVATVGYDPFFLALGLLDLV
GAAVLWTLVRDRPVRAPVSELPAA

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=339, Percent_Identity=27.1386430678466, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI9945322, Length=407, Percent_Identity=22.8501228501229, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI9966811, Length=407, Percent_Identity=22.3587223587224, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI21322234, Length=407, Percent_Identity=22.3587223587224, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI2367193, Length=416, Percent_Identity=45.9134615384615, Blast_Score=371, Evalue=1e-104,
Organism=Escherichia coli, GI1789515, Length=398, Percent_Identity=29.1457286432161, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI87082320, Length=413, Percent_Identity=26.634382566586, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1789152, Length=422, Percent_Identity=26.0663507109005, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI2367379, Length=426, Percent_Identity=27.4647887323944, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87082071, Length=409, Percent_Identity=24.9388753056235, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87082310, Length=414, Percent_Identity=23.6714975845411, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17552542, Length=228, Percent_Identity=30.2631578947368, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17554962, Length=372, Percent_Identity=23.1182795698925, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71997452, Length=389, Percent_Identity=22.107969151671, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17554148, Length=363, Percent_Identity=23.4159779614325, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20130167, Length=388, Percent_Identity=26.5463917525773, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573708, Length=369, Percent_Identity=27.10027100271, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28573707, Length=369, Percent_Identity=27.10027100271, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI20129235, Length=282, Percent_Identity=27.6595744680851, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24584153, Length=306, Percent_Identity=23.5294117647059, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24658658, Length=401, Percent_Identity=23.6907730673317, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24648416, Length=433, Percent_Identity=21.2471131639723, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356189, Length=433, Percent_Identity=21.2471131639723, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550460, Length=402, Percent_Identity=25.1243781094527, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24639764, Length=370, Percent_Identity=24.5945945945946, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24655255, Length=354, Percent_Identity=25.4237288135593, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24655271, Length=435, Percent_Identity=23.2183908045977, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20130135, Length=435, Percent_Identity=23.2183908045977, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24580790, Length=323, Percent_Identity=24.4582043343653, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24654215, Length=327, Percent_Identity=24.1590214067278, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583789, Length=308, Percent_Identity=25.3246753246753, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573299, Length=321, Percent_Identity=27.4143302180685, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641682, Length=250, Percent_Identity=26.4, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI19922400, Length=310, Percent_Identity=24.1935483870968, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24658666, Length=385, Percent_Identity=24.6753246753247, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI45550495, Length=408, Percent_Identity=24.0196078431373, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24658696, Length=318, Percent_Identity=24.8427672955975, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46007; Mature: 46007

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLWALRWWIIALVMLGAMLNYLTRATMGVAAPTMLADLSISEREYGWITGAFQAGIML
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHCCEEE
QPAVGYVLDTLGLRTGLAIFAGAWSAISIAHGFASTWPAFAALRGLLGFAEGSANPAGMK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
VVATWFPARERGFAGGVYNIGASFGTMLAPPLVAWAILAFNWRAAFIITGLLGLVWTALW
EEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
WWGFRTPDQHPRLSPQERAKILEGQEPDLHDDGARPSMLKLMARRDFWGIAIPRLLADPT
HHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCC
WGTLAFWIPLYLVQTRGFDLKQIAMFAWLPFLAADLGCLFGPAVVEFLQRRGVSLINARR
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
GAFTLGALMMTGMMFVGRVESPYLAIALLCLGGFAHQTLSVTVITMASDLFKRNEVATVA
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
GMAGTFGNLGVLIFSLLIGGLVATVGYDPFFLALGLLDLVGAAVLWTLVRDRPVRAPVSE
HHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LPAA
CCCC
>Mature Secondary Structure
MRRLWALRWWIIALVMLGAMLNYLTRATMGVAAPTMLADLSISEREYGWITGAFQAGIML
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHCCEEE
QPAVGYVLDTLGLRTGLAIFAGAWSAISIAHGFASTWPAFAALRGLLGFAEGSANPAGMK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
VVATWFPARERGFAGGVYNIGASFGTMLAPPLVAWAILAFNWRAAFIITGLLGLVWTALW
EEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
WWGFRTPDQHPRLSPQERAKILEGQEPDLHDDGARPSMLKLMARRDFWGIAIPRLLADPT
HHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCC
WGTLAFWIPLYLVQTRGFDLKQIAMFAWLPFLAADLGCLFGPAVVEFLQRRGVSLINARR
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
GAFTLGALMMTGMMFVGRVESPYLAIALLCLGGFAHQTLSVTVITMASDLFKRNEVATVA
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
GMAGTFGNLGVLIFSLLIGGLVATVGYDPFFLALGLLDLVGAAVLWTLVRDRPVRAPVSE
HHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LPAA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: galacturonate [Periplasm]; Proton [Periplasm]; glucuronate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + galacturonate [Periplasm] = galacturonate [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + glucuronate [Periplasm] = Proton [Cytoplasm] + glucuronate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]