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The map label for this gene is uxaA [H]

Identifier: 197105918

GI number: 197105918

Start: 2808956

End: 2810434

Strand: Direct

Name: uxaA [H]

Synonym: PHZ_c2457

Alternate gene names: 197105918

Gene position: 2808956-2810434 (Clockwise)

Preceding gene: 197105916

Following gene: 197105919

Centisome position: 70.29

GC content: 74.17

Gene sequence:

>1479_bases
ATGACCGAACCGGCCGACGCCCTGATCATCGACCCGCGCGACGACGTCGCCGTGGCCGTGCGCCCCGTGGCGGCCGGGGA
GGAGCTCCTGGGCGTGCGGGCGGCCGCGGACATCCCCGCCGGCCACAAGATGGCGGTCAGGGCCGTCCCCGCTGGCGGCG
AGGTGCGCAAGTACGGCTGGCCGATCGGGCGCGCCACCGCCGACATCCGGCCCGGGGACCACGTCCACACCCACAACCTC
GCCACGGCCCTCTCGACGCACGAGGACTACGCCTGGCGGCTGGCCCCGGCCGAGCCGCTGCCGGACACCCCCGGGACCTT
CCAGGGCTATCGGCGCAAGGACGGGCGGGTCGGCACGCGCAACGAGATCTGGATCCTGTGCACCGTCGGCTGCGTCGCCC
GCACGGCCCAGCGCATCGCCGAGCAGGCGCGGCGGCGGTTCGAGGGCCGCGTCGACGGCGTCCACGCCCTGACCCATCCC
TTCGGCTGCTCGCAGCTGGGCGGCGACCTCGACGCCACCCGCGCGATGATCGCGGCCCTCGCCGGCCACCCCAACGCGGG
CGGCGTGCTGATCCTGGGCCTCGGCTGCGAGAGCAACCAGCTTTCGGCCCTGCTGGAGGCCGCGCCGCACCTCGACCGGG
AACGCCTGCGCGCCTTCACCGCCCAGGCCTCGGAGGACGAGCTGGAGGAGGGGCTGAAGGCCGTCGAAGAGCTGGTCGTC
GTCGCCGAGGGGGACCGCCGCGAGCCCTGCCCGGTCTCGGATCTGGTGATCGGCGTGAAGTGCGGCGGCTCGGACGGCTT
TTCGGGCCTGACCGCCAATCCGCTGGTGGGCCGTATCGCCGACAAGGTCTGCGGGGCGGGCGGTACGGCGGTGCTGACCG
AGATTCCCGAGATCTTCGGCGCCGAACAGCTGCTGATGGCGCGGGCCCGGGACGAGGCGGTGTTCCGCGGCCTCGCCGAC
GTCGTGAACGACTTCAAGGCCTACTTCACGCGCCACGGAGAGCCGGTCAGCGAGAACCCCTCCCCCGGCAACATCGCGGG
CGGCATCACCACCCTGGAGGAGAAGTCGCTGGGCGCCGTCCAGAAGGCGGGCCGCGGGCCCGTCACCGAGGTGGTCCGCT
ACGGCGGCCAGGCGCACGAGCCGGGCGTCGTGCTGCTGGAGGCCCCCGGGAACGACGCGGTCTCCTCCACCGCCCTGACC
GCGGCGGGCGCGACCGTGATCCTGTTCACCACCGGCCGGGGCACGCCGCTGGGCTTCCCCGCCCCCACCCTGAAGATCGC
CACCAACTCGGGCCTCGCCCAGCGCAAGCCGCACTGGATCGACTTCGACGCCGGCCGCATCGCCGCCGGCGAGAGCCTGG
ACGCCGCCGCCGACCGGCTGATGGACCTGGTGCTGGCCACCGCGAGCGGCCGGCCGACCCAGGCCGAGGAGAACGGCGAA
CGCGAGATCGCCCTCTGGAAACGCGGGGTCACCCTGTGA

Upstream 100 bases:

>100_bases
TAATCGCAAGCGCGGGAGATTCAAAATCCGGGTTTGTACGGATCGCACGGAATGCGACGCCGCCGCTTGAGCTTTTGATG
ACACCGGTTACCATTTTGCG

Downstream 100 bases:

>100_bases
AGCGCCTCTCCGACGCGACGCTGGCCCAGGCCGGCGCGCCCGTGCTCACGCCGGCCTACGACCGAACGACCCTGCGCACC
GGCGTGGTCCACTTCGGCCC

Product: altronate hydrolase

Products: NA

Alternate protein names: Altronic acid hydratase [H]

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MTEPADALIIDPRDDVAVAVRPVAAGEELLGVRAAADIPAGHKMAVRAVPAGGEVRKYGWPIGRATADIRPGDHVHTHNL
ATALSTHEDYAWRLAPAEPLPDTPGTFQGYRRKDGRVGTRNEIWILCTVGCVARTAQRIAEQARRRFEGRVDGVHALTHP
FGCSQLGGDLDATRAMIAALAGHPNAGGVLILGLGCESNQLSALLEAAPHLDRERLRAFTAQASEDELEEGLKAVEELVV
VAEGDRREPCPVSDLVIGVKCGGSDGFSGLTANPLVGRIADKVCGAGGTAVLTEIPEIFGAEQLLMARARDEAVFRGLAD
VVNDFKAYFTRHGEPVSENPSPGNIAGGITTLEEKSLGAVQKAGRGPVTEVVRYGGQAHEPGVVLLEAPGNDAVSSTALT
AAGATVILFTTGRGTPLGFPAPTLKIATNSGLAQRKPHWIDFDAGRIAAGESLDAAADRLMDLVLATASGRPTQAEENGE
REIALWKRGVTL

Sequences:

>Translated_492_residues
MTEPADALIIDPRDDVAVAVRPVAAGEELLGVRAAADIPAGHKMAVRAVPAGGEVRKYGWPIGRATADIRPGDHVHTHNL
ATALSTHEDYAWRLAPAEPLPDTPGTFQGYRRKDGRVGTRNEIWILCTVGCVARTAQRIAEQARRRFEGRVDGVHALTHP
FGCSQLGGDLDATRAMIAALAGHPNAGGVLILGLGCESNQLSALLEAAPHLDRERLRAFTAQASEDELEEGLKAVEELVV
VAEGDRREPCPVSDLVIGVKCGGSDGFSGLTANPLVGRIADKVCGAGGTAVLTEIPEIFGAEQLLMARARDEAVFRGLAD
VVNDFKAYFTRHGEPVSENPSPGNIAGGITTLEEKSLGAVQKAGRGPVTEVVRYGGQAHEPGVVLLEAPGNDAVSSTALT
AAGATVILFTTGRGTPLGFPAPTLKIATNSGLAQRKPHWIDFDAGRIAAGESLDAAADRLMDLVLATASGRPTQAEENGE
REIALWKRGVTL
>Mature_491_residues
TEPADALIIDPRDDVAVAVRPVAAGEELLGVRAAADIPAGHKMAVRAVPAGGEVRKYGWPIGRATADIRPGDHVHTHNLA
TALSTHEDYAWRLAPAEPLPDTPGTFQGYRRKDGRVGTRNEIWILCTVGCVARTAQRIAEQARRRFEGRVDGVHALTHPF
GCSQLGGDLDATRAMIAALAGHPNAGGVLILGLGCESNQLSALLEAAPHLDRERLRAFTAQASEDELEEGLKAVEELVVV
AEGDRREPCPVSDLVIGVKCGGSDGFSGLTANPLVGRIADKVCGAGGTAVLTEIPEIFGAEQLLMARARDEAVFRGLADV
VNDFKAYFTRHGEPVSENPSPGNIAGGITTLEEKSLGAVQKAGRGPVTEVVRYGGQAHEPGVVLLEAPGNDAVSSTALTA
AGATVILFTTGRGTPLGFPAPTLKIATNSGLAQRKPHWIDFDAGRIAAGESLDAAADRLMDLVLATASGRPTQAEENGER
EIALWKRGVTL

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789475, Length=499, Percent_Identity=49.0981963927856, Blast_Score=465, Evalue=1e-132,
Organism=Escherichia coli, GI1789516, Length=474, Percent_Identity=35.6540084388186, Blast_Score=247, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.7 [H]

Molecular weight: Translated: 51612; Mature: 51481

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPADALIIDPRDDVAVAVRPVAAGEELLGVRAAADIPAGHKMAVRAVPAGGEVRKYGW
CCCCCCEEEECCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHCCC
PIGRATADIRPGDHVHTHNLATALSTHEDYAWRLAPAEPLPDTPGTFQGYRRKDGRVGTR
CCCCCCCCCCCCCCEEHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHCCCCCCCCC
NEIWILCTVGCVARTAQRIAEQARRRFEGRVDGVHALTHPFGCSQLGGDLDATRAMIAAL
CCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHCCCHHHHHHHHHHH
AGHPNAGGVLILGLGCESNQLSALLEAAPHLDRERLRAFTAQASEDELEEGLKAVEELVV
HCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHEEE
VAEGDRREPCPVSDLVIGVKCGGSDGFSGLTANPLVGRIADKVCGAGGTAVLTEIPEIFG
EECCCCCCCCCHHHEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHC
AEQLLMARARDEAVFRGLADVVNDFKAYFTRHGEPVSENPSPGNIAGGITTLEEKSLGAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHH
QKAGRGPVTEVVRYGGQAHEPGVVLLEAPGNDAVSSTALTAAGATVILFTTGRGTPLGFP
HHCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHEECCCEEEEEECCCCCCCCCC
APTLKIATNSGLAQRKPHWIDFDAGRIAAGESLDAAADRLMDLVLATASGRPTQAEENGE
CCEEEEEECCCCCCCCCCEEECCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
REIALWKRGVTL
CEEEEECCCCCC
>Mature Secondary Structure 
TEPADALIIDPRDDVAVAVRPVAAGEELLGVRAAADIPAGHKMAVRAVPAGGEVRKYGW
CCCCCEEEECCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHCCC
PIGRATADIRPGDHVHTHNLATALSTHEDYAWRLAPAEPLPDTPGTFQGYRRKDGRVGTR
CCCCCCCCCCCCCCEEHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHCCCCCCCCC
NEIWILCTVGCVARTAQRIAEQARRRFEGRVDGVHALTHPFGCSQLGGDLDATRAMIAAL
CCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHCCCHHHHHHHHHHH
AGHPNAGGVLILGLGCESNQLSALLEAAPHLDRERLRAFTAQASEDELEEGLKAVEELVV
HCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHEEE
VAEGDRREPCPVSDLVIGVKCGGSDGFSGLTANPLVGRIADKVCGAGGTAVLTEIPEIFG
EECCCCCCCCCHHHEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHC
AEQLLMARARDEAVFRGLADVVNDFKAYFTRHGEPVSENPSPGNIAGGITTLEEKSLGAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHH
QKAGRGPVTEVVRYGGQAHEPGVVLLEAPGNDAVSSTALTAAGATVILFTTGRGTPLGFP
HHCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHEECCCEEEEEECCCCCCCCCC
APTLKIATNSGLAQRKPHWIDFDAGRIAAGESLDAAADRLMDLVLATASGRPTQAEENGE
CCEEEEEECCCCCCCCCCEEECCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
REIALWKRGVTL
CEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 3038546 [H]