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The map label for this gene is uxaC

Identifier: 197105913

GI number: 197105913

Start: 2803543

End: 2804985

Strand: Reverse

Name: uxaC

Synonym: PHZ_c2452

Alternate gene names: 197105913

Gene position: 2804985-2803543 (Counterclockwise)

Preceding gene: 197105917

Following gene: 197105912

Centisome position: 70.19

GC content: 70.69

Gene sequence:

>1443_bases
ATGACAAGGCCGCTGAGGCTGCATCCGGACCGCTTGTTCCCGGCCGACGCCGGCACGCGCGACATCGCCCGCCGTCTCTA
CGGGTCCGTGAAGGACCTGCCGATCATCAGCCCGCACGGCCACACCGATCCCGAGTGGTTCGCGGGCGACGCGCCGTTCC
CCGACGCAACCAACCTGTTCCTGGCCCCCGACCACTACCTCTACCGGATGCTCTATTCGCAGGGCGTGCCCCTGGACCGG
CTGGGCGTCCCGTCGAAGGCGGGCCCGTCCCCGGCCGACCCGCGCGAGGCCTGGCGGATGCTGGCGTCCAACATGCACCT
GTTCCGCGGCACGCCCTCGTCCATGTGGCTGAACCATGTGTTCGGCGAGGTGTTCGGCTTCGAGATCGAGCTGTCGGCCG
AGACCGCCGACCTCTACTTCGACCGCATCGGCGAGGCGCTGCAGAGCCCCGCCTTCCGGCCGCGGGCCCTGTTCGAGCGG
TTCAACATCGAACTGCTGGCCACCACCGAGAGCCCCACCGACGACCTGCGCCACCACAAGGCCATGCGCGCCAGCGGCTG
GAAGGGCCGGGTGGTCACCGCCTACCGCCCCGACCCGGTGATCGACGCCGAGCACGAGGACTTCCGCGCGAGCCTTTCCC
GCTTCGGCGAGCTGACCGGACAGGACGTCGAGAGCTGGTCAGGCTATCTCCAGGCGCACCGGATGCGCCGGGCGGCGTTC
ATGGAGATGGGCGCCACCTCCACCGACCACGGCCACCCGACCGCGGCCACCGCCGACCTGTCGCTGGCTGACGCCGAGGC
GCTGTTCCGCAAGCTGCTGTCGGCCGACTTCTCGCCCGCCGACGCCGAGCTGTTCCGGGCCCAGATGCTGACCGAGATGG
CCAGGATGAGCCTGGACGACGGGCTGGTCATGCAGATCCACCCCGGCTCGTTCCGCAACCACAACGCCGGCCTCTTCGCC
CGCTACGGGCGGGACAAGGGCGCCGACATCCCCACCCGGACCGACTACGTCCGGGCGCTGAAGCCGCTGCTGGACCGCTT
CGGCAACGAGCGCGGCCTGTCGGTCATCGTCTTCACGCTGGACGAGAGCAGCTACGCCCGCGAGCTCGCGCCGCTGGCCG
GCCACTATCCGGTGCTGAAGCTGGGCCCCGCCTGGTGGTTCCACGACAGCCCGGAAGGCATGCGCCGGTTCCGCGAGCAG
ACCACCGAGACGGCGGGCTTCTACAACACGGTCGGCTTCAACGACGACACCCGGGCGTTCCTTTCGATCCCGGCCCGGCA
TGACGTCGCCCGGCGGATCGACGCCGGCTTCCTCGCCCGGCTGGTGGCCGAGCACCGCCTATCCGAGGACGACGCCCACG
AGACGGCGGTCGACCTCGCCTACAACCTGCCCAAGCGGGCCTACAAGCTGGACGAGCCGGCCAGGACGCCGGCCGCCGCC
TGA

Upstream 100 bases:

>100_bases
TTTCTGCTTCACTCAGGAAAGCCTCGGCAGCCGTCCGGCAAAGAGGTTGCGTGGCGTGATGACACCGGTTACCGAGGCCG
CTTCAAGGGAGGACAGGTCG

Downstream 100 bases:

>100_bases
CGACAGGAGACGTGTACGTGTTCAAGCGCATCTACCACGCGACCCACCCCGACATGATGGAGGGCGTCGACAACGAGACC
CTGCGCCAGCGCTACCTGAT

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MTRPLRLHPDRLFPADAGTRDIARRLYGSVKDLPIISPHGHTDPEWFAGDAPFPDATNLFLAPDHYLYRMLYSQGVPLDR
LGVPSKAGPSPADPREAWRMLASNMHLFRGTPSSMWLNHVFGEVFGFEIELSAETADLYFDRIGEALQSPAFRPRALFER
FNIELLATTESPTDDLRHHKAMRASGWKGRVVTAYRPDPVIDAEHEDFRASLSRFGELTGQDVESWSGYLQAHRMRRAAF
MEMGATSTDHGHPTAATADLSLADAEALFRKLLSADFSPADAELFRAQMLTEMARMSLDDGLVMQIHPGSFRNHNAGLFA
RYGRDKGADIPTRTDYVRALKPLLDRFGNERGLSVIVFTLDESSYARELAPLAGHYPVLKLGPAWWFHDSPEGMRRFREQ
TTETAGFYNTVGFNDDTRAFLSIPARHDVARRIDAGFLARLVAEHRLSEDDAHETAVDLAYNLPKRAYKLDEPARTPAAA

Sequences:

>Translated_480_residues
MTRPLRLHPDRLFPADAGTRDIARRLYGSVKDLPIISPHGHTDPEWFAGDAPFPDATNLFLAPDHYLYRMLYSQGVPLDR
LGVPSKAGPSPADPREAWRMLASNMHLFRGTPSSMWLNHVFGEVFGFEIELSAETADLYFDRIGEALQSPAFRPRALFER
FNIELLATTESPTDDLRHHKAMRASGWKGRVVTAYRPDPVIDAEHEDFRASLSRFGELTGQDVESWSGYLQAHRMRRAAF
MEMGATSTDHGHPTAATADLSLADAEALFRKLLSADFSPADAELFRAQMLTEMARMSLDDGLVMQIHPGSFRNHNAGLFA
RYGRDKGADIPTRTDYVRALKPLLDRFGNERGLSVIVFTLDESSYARELAPLAGHYPVLKLGPAWWFHDSPEGMRRFREQ
TTETAGFYNTVGFNDDTRAFLSIPARHDVARRIDAGFLARLVAEHRLSEDDAHETAVDLAYNLPKRAYKLDEPARTPAAA
>Mature_479_residues
TRPLRLHPDRLFPADAGTRDIARRLYGSVKDLPIISPHGHTDPEWFAGDAPFPDATNLFLAPDHYLYRMLYSQGVPLDRL
GVPSKAGPSPADPREAWRMLASNMHLFRGTPSSMWLNHVFGEVFGFEIELSAETADLYFDRIGEALQSPAFRPRALFERF
NIELLATTESPTDDLRHHKAMRASGWKGRVVTAYRPDPVIDAEHEDFRASLSRFGELTGQDVESWSGYLQAHRMRRAAFM
EMGATSTDHGHPTAATADLSLADAEALFRKLLSADFSPADAELFRAQMLTEMARMSLDDGLVMQIHPGSFRNHNAGLFAR
YGRDKGADIPTRTDYVRALKPLLDRFGNERGLSVIVFTLDESSYARELAPLAGHYPVLKLGPAWWFHDSPEGMRRFREQT
TETAGFYNTVGFNDDTRAFLSIPARHDVARRIDAGFLARLVAEHRLSEDDAHETAVDLAYNLPKRAYKLDEPARTPAAA

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family

Homologues:

Organism=Escherichia coli, GI2367192, Length=433, Percent_Identity=26.7898383371824, Blast_Score=152, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UXAC_PHEZH (B4RGF5)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002131290.1
- GeneID:   6791973
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c2452
- HOGENOM:   HBG293306
- OMA:   AWAKTVP
- ProtClustDB:   PRK02925
- HAMAP:   MF_00675
- InterPro:   IPR003766
- InterPro:   IPR023177
- Gene3D:   G3DSA:1.10.2020.10

Pfam domain/function: PF02614 UxaC

EC number: =5.3.1.12

Molecular weight: Translated: 53883; Mature: 53752

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPLRLHPDRLFPADAGTRDIARRLYGSVKDLPIISPHGHTDPEWFAGDAPFPDATNLF
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEE
LAPDHYLYRMLYSQGVPLDRLGVPSKAGPSPADPREAWRMLASNMHLFRGTPSSMWLNHV
ECCHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEECCCCHHHHHHHH
FGEVFGFEIELSAETADLYFDRIGEALQSPAFRPRALFERFNIELLATTESPTDDLRHHK
HHHHHCEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCEEEEEECCCCHHHHHHHH
AMRASGWKGRVVTAYRPDPVIDAEHEDFRASLSRFGELTGQDVESWSGYLQAHRMRRAAF
HHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
MEMGATSTDHGHPTAATADLSLADAEALFRKLLSADFSPADAELFRAQMLTEMARMSLDD
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
GLVMQIHPGSFRNHNAGLFARYGRDKGADIPTRTDYVRALKPLLDRFGNERGLSVIVFTL
CEEEEECCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEE
DESSYARELAPLAGHYPVLKLGPAWWFHDSPEGMRRFREQTTETAGFYNTVGFNDDTRAF
CCCHHHHHHHHHHCCCCEEEECCEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCCCEE
LSIPARHDVARRIDAGFLARLVAEHRLSEDDAHETAVDLAYNLPKRAYKLDEPARTPAAA
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TRPLRLHPDRLFPADAGTRDIARRLYGSVKDLPIISPHGHTDPEWFAGDAPFPDATNLF
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEE
LAPDHYLYRMLYSQGVPLDRLGVPSKAGPSPADPREAWRMLASNMHLFRGTPSSMWLNHV
ECCHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEECCCCHHHHHHHH
FGEVFGFEIELSAETADLYFDRIGEALQSPAFRPRALFERFNIELLATTESPTDDLRHHK
HHHHHCEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCEEEEEECCCCHHHHHHHH
AMRASGWKGRVVTAYRPDPVIDAEHEDFRASLSRFGELTGQDVESWSGYLQAHRMRRAAF
HHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
MEMGATSTDHGHPTAATADLSLADAEALFRKLLSADFSPADAELFRAQMLTEMARMSLDD
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
GLVMQIHPGSFRNHNAGLFARYGRDKGADIPTRTDYVRALKPLLDRFGNERGLSVIVFTL
CEEEEECCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEE
DESSYARELAPLAGHYPVLKLGPAWWFHDSPEGMRRFREQTTETAGFYNTVGFNDDTRAF
CCCHHHHHHHHHHCCCCEEEECCEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCCCEE
LSIPARHDVARRIDAGFLARLVAEHRLSEDDAHETAVDLAYNLPKRAYKLDEPARTPAAA
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA