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The map label for this gene is dcm [C]

Identifier: 197105892

GI number: 197105892

Start: 2775586

End: 2777112

Strand: Direct

Name: dcm [C]

Synonym: PHZ_c2431

Alternate gene names: 197105892

Gene position: 2775586-2777112 (Clockwise)

Preceding gene: 197105888

Following gene: 197105893

Centisome position: 69.45

GC content: 65.95

Gene sequence:

>1527_bases
ATACGGCCGCCAGGAACGGGCGAGCGGGCGCGCAGGGTGATGAGCAAAGACCCGACTGTCCTGGCGCGCATCGCACGTCT
GAAGTCCGGCGCGCCGCCCCGCGTCCTGGACCTGTTCTCAGGCTGCGGCGGGCTGTCCCTCGGCTTTCACGCCCAGGGGT
TCGATATCGTCGCCGCTGTCGAGTTTGATCCGGCGGCGGCTGCGTCTCATGGGGCCAACTTCCATCCGGAAGATCCGCGT
CATGGACGACCGAGGGATATCACCAGACTGACTCCGGAGCAGCTGGCGCTTGAACTCGATCTCGGTCCTGTCGAGCAGGC
CGTCGATGTACTGGTGGGCGGCCCACCCTGTCAGGCGTTTGCCCGCGTCGGCCGTTCAAAGCTGCGGGAGATCGCCGAGC
ATCCCGAAGCTTTCAGGCTGGATGCGCGAGCCCGTCTCTATCTCGAGTACCTCCGCTACGTTCAGGCCTTTCTGCCGCTC
GCCGTGGTGATGGAGAACGTCCCGGACGTCCTCAATCACGGCGGCCAGAACGTGGCAGAGGAGACCCGCACCTTCCTCGA
AGAGCTGGGCTATGACGTAAAGTACAGCCTTCTGAACGCCGCCTTTTACGGCGTGCCGCAGATGCGCGAGCGGATGATCC
TGATCGCGACGCGGCGGGAGCTGGGCGTAGAGATCCGGTTCCCGGCTCCCACCCATCACATTGAGCTTCCGCCCGGCTAC
GCGGGAAGCCGGCAGGTGGCGCTGAAGCTGCTCAATCAGGGCGCGCTTCTCGATACGGCGCCAGGCTATCAGCCAGCCCT
GTCGCCCGACCGGAGCCTTCCGTCGGCTGTGACTGCAGCGGAGGCGCTCGGAGATCTGCCCGAGATCACCGGACACCTTC
GGGGCGAAATCCGGCGCGGCGCCCGACGGTTTGACGCGCTGGTTCGCTATCCGCACGAGCCACGCTCCGACTACGCGACC
CTGATGCGCTCCTGGCCAAGCTTCGAGAACGCCGAAGGCGTGCGGGATCATGTGATCCGCTACCTTCCGCGGGACTGGAA
GCTTTTCGGGCGTCTGCGGCCCGGGGACCAGTATCCCGAAGCCCATGCCGAAGCCGTGAGAATGTTCAACGAGGCGCTTC
GCGATCTGCAGGTACAGGGTCGGGCGCCGCGGCCGCACAGCGCCGAATGGCGGCAGCTTCGCGCGTCGATCGTGCCCCCA
TACGACGTCGGAAAGTTTCCGAACAAGTGGCGGAAGATGGAGCCGGACCTTCCCGCCAGAACGCTGATGGCGCATCTGGG
GAAGGACAGCTACAGCCACATTCACTATGACAGCGCTCAGTCCCGCACCATCTCGGTTCGAGAAGCTGCGCGTCTGCAGT
CGTTCCCCGATGGTTTTGTCTTCAAGGGCGCCATGAACGCGGCCTTCCGCCAGATCGGCAACGCCGTGCCTCCCCTTCTG
GCCCGGGCGGTCGCCGGCGAGATTGCAGCGGCGTTCCAGCGGGCGATGGCGCCTGATCGTCCGCGTACGGGCCGGCTGGC
CGCCTGA

Upstream 100 bases:

>100_bases
TCGAGGAGGCGGGCCGGTTCGAGGCGTTCTGCCAGGACCGCGGCCACAAGAAGTCGACGCTGATCGCCCGCCTCATCCGT
GACCACCTCGACCGCGAGGG

Downstream 100 bases:

>100_bases
GTTGTCGCCTCGGCAGGCCAGTCGCGCAGATCCGCTGACGCCCCAGCAGCGACGGCGGAATATGGCGGCCATCCGCGCGG
CGAACACGAAGCCAGAGATG

Product: DNA (cytosine-5-)-methyltransferase protein

Products: NA

Alternate protein names: Cytosine-specific methyltransferase; M.OihORF3336P [H]

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MRPPGTGERARRVMSKDPTVLARIARLKSGAPPRVLDLFSGCGGLSLGFHAQGFDIVAAVEFDPAAAASHGANFHPEDPR
HGRPRDITRLTPEQLALELDLGPVEQAVDVLVGGPPCQAFARVGRSKLREIAEHPEAFRLDARARLYLEYLRYVQAFLPL
AVVMENVPDVLNHGGQNVAEETRTFLEELGYDVKYSLLNAAFYGVPQMRERMILIATRRELGVEIRFPAPTHHIELPPGY
AGSRQVALKLLNQGALLDTAPGYQPALSPDRSLPSAVTAAEALGDLPEITGHLRGEIRRGARRFDALVRYPHEPRSDYAT
LMRSWPSFENAEGVRDHVIRYLPRDWKLFGRLRPGDQYPEAHAEAVRMFNEALRDLQVQGRAPRPHSAEWRQLRASIVPP
YDVGKFPNKWRKMEPDLPARTLMAHLGKDSYSHIHYDSAQSRTISVREAARLQSFPDGFVFKGAMNAAFRQIGNAVPPLL
ARAVAGEIAAAFQRAMAPDRPRTGRLAA

Sequences:

>Translated_508_residues
MRPPGTGERARRVMSKDPTVLARIARLKSGAPPRVLDLFSGCGGLSLGFHAQGFDIVAAVEFDPAAAASHGANFHPEDPR
HGRPRDITRLTPEQLALELDLGPVEQAVDVLVGGPPCQAFARVGRSKLREIAEHPEAFRLDARARLYLEYLRYVQAFLPL
AVVMENVPDVLNHGGQNVAEETRTFLEELGYDVKYSLLNAAFYGVPQMRERMILIATRRELGVEIRFPAPTHHIELPPGY
AGSRQVALKLLNQGALLDTAPGYQPALSPDRSLPSAVTAAEALGDLPEITGHLRGEIRRGARRFDALVRYPHEPRSDYAT
LMRSWPSFENAEGVRDHVIRYLPRDWKLFGRLRPGDQYPEAHAEAVRMFNEALRDLQVQGRAPRPHSAEWRQLRASIVPP
YDVGKFPNKWRKMEPDLPARTLMAHLGKDSYSHIHYDSAQSRTISVREAARLQSFPDGFVFKGAMNAAFRQIGNAVPPLL
ARAVAGEIAAAFQRAMAPDRPRTGRLAA
>Mature_508_residues
MRPPGTGERARRVMSKDPTVLARIARLKSGAPPRVLDLFSGCGGLSLGFHAQGFDIVAAVEFDPAAAASHGANFHPEDPR
HGRPRDITRLTPEQLALELDLGPVEQAVDVLVGGPPCQAFARVGRSKLREIAEHPEAFRLDARARLYLEYLRYVQAFLPL
AVVMENVPDVLNHGGQNVAEETRTFLEELGYDVKYSLLNAAFYGVPQMRERMILIATRRELGVEIRFPAPTHHIELPPGY
AGSRQVALKLLNQGALLDTAPGYQPALSPDRSLPSAVTAAEALGDLPEITGHLRGEIRRGARRFDALVRYPHEPRSDYAT
LMRSWPSFENAEGVRDHVIRYLPRDWKLFGRLRPGDQYPEAHAEAVRMFNEALRDLQVQGRAPRPHSAEWRQLRASIVPP
YDVGKFPNKWRKMEPDLPARTLMAHLGKDSYSHIHYDSAQSRTISVREAARLQSFPDGFVFKGAMNAAFRQIGNAVPPLL
ARAVAGEIAAAFQRAMAPDRPRTGRLAA

Specific function: This methylase recognizes the double-stranded sequence ACCGGT, causes specific methylation on C-? on both strands, and protects the DNA from cleavage by a specific endonuclease (Potential) [H]

COG id: COG0270

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C5-methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI4503351, Length=496, Percent_Identity=28.2258064516129, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI195927037, Length=496, Percent_Identity=28.2258064516129, Blast_Score=120, Evalue=4e-27,
Organism=Escherichia coli, GI1788271, Length=208, Percent_Identity=30.2884615384615, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018117
- InterPro:   IPR001525 [H]

Pfam domain/function: PF00145 DNA_methylase [H]

EC number: =2.1.1.37 [H]

Molecular weight: Translated: 56419; Mature: 56419

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS00095 C5_MTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPPGTGERARRVMSKDPTVLARIARLKSGAPPRVLDLFSGCGGLSLGFHAQGFDIVAAV
CCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEE
EFDPAAAASHGANFHPEDPRHGRPRDITRLTPEQLALELDLGPVEQAVDVLVGGPPCQAF
ECCCHHHHCCCCCCCCCCCCCCCCCCHHHCCHHHHEEECCCCHHHHHHHHHCCCCCHHHH
ARVGRSKLREIAEHPEAFRLDARARLYLEYLRYVQAFLPLAVVMENVPDVLNHGGQNVAE
HHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ETRTFLEELGYDVKYSLLNAAFYGVPQMRERMILIATRRELGVEIRFPAPTHHIELPPGY
HHHHHHHHHCCCHHHHHHHHHHHCCHHHHCCEEEEEEHHHHCEEEECCCCCCEEECCCCC
AGSRQVALKLLNQGALLDTAPGYQPALSPDRSLPSAVTAAEALGDLPEITGHLRGEIRRG
CCHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
ARRFDALVRYPHEPRSDYATLMRSWPSFENAEGVRDHVIRYLPRDWKLFGRLRPGDQYPE
HHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHCCCCCCCCCCH
AHAEAVRMFNEALRDLQVQGRAPRPHSAEWRQLRASIVPPYDVGKFPNKWRKMEPDLPAR
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCHH
TLMAHLGKDSYSHIHYDSAQSRTISVREAARLQSFPDGFVFKGAMNAAFRQIGNAVPPLL
HHHHHHCCCCCCEEEECCCCCCEEHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCHHHH
ARAVAGEIAAAFQRAMAPDRPRTGRLAA
HHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MRPPGTGERARRVMSKDPTVLARIARLKSGAPPRVLDLFSGCGGLSLGFHAQGFDIVAAV
CCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEE
EFDPAAAASHGANFHPEDPRHGRPRDITRLTPEQLALELDLGPVEQAVDVLVGGPPCQAF
ECCCHHHHCCCCCCCCCCCCCCCCCCHHHCCHHHHEEECCCCHHHHHHHHHCCCCCHHHH
ARVGRSKLREIAEHPEAFRLDARARLYLEYLRYVQAFLPLAVVMENVPDVLNHGGQNVAE
HHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ETRTFLEELGYDVKYSLLNAAFYGVPQMRERMILIATRRELGVEIRFPAPTHHIELPPGY
HHHHHHHHHCCCHHHHHHHHHHHCCHHHHCCEEEEEEHHHHCEEEECCCCCCEEECCCCC
AGSRQVALKLLNQGALLDTAPGYQPALSPDRSLPSAVTAAEALGDLPEITGHLRGEIRRG
CCHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
ARRFDALVRYPHEPRSDYATLMRSWPSFENAEGVRDHVIRYLPRDWKLFGRLRPGDQYPE
HHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHCCCCCCCCCCH
AHAEAVRMFNEALRDLQVQGRAPRPHSAEWRQLRASIVPPYDVGKFPNKWRKMEPDLPAR
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCHH
TLMAHLGKDSYSHIHYDSAQSRTISVREAARLQSFPDGFVFKGAMNAAFRQIGNAVPPLL
HHHHHHCCCCCCEEEECCCCCCEEHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCHHHH
ARAVAGEIAAAFQRAMAPDRPRTGRLAA
HHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]