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The map label for this gene is hyuA [H]

Identifier: 197105872

GI number: 197105872

Start: 2746772

End: 2748334

Strand: Direct

Name: hyuA [H]

Synonym: PHZ_c2411

Alternate gene names: 197105872

Gene position: 2746772-2748334 (Clockwise)

Preceding gene: 197105871

Following gene: 197105873

Centisome position: 68.73

GC content: 68.33

Gene sequence:

>1563_bases
ATGCGAATTGGGGTGGATGTCGGCGGCACCAACACGGACGCCGCATTGATCCGGGGCCGGGAGGTGGTCGCGGCGGTGAA
GCGCCCGACGACCGCCGACGTGAAATCAGGGATCATCGCCGCGATCGAGGCGCTGATCTTGGAGGCTGAGGTGAATGCCG
AGGCCATCCGGGCCGTGATGATCGGCACCACGCACTTCACCAACGCCTTCGTGCAGCGGCGCGAGCTCACCAGGGTTTTC
GCCCTGCGGATCGGCGCGCCCGCCTCGCGTGGCGTACCGCCATTCTCGGGATGGCCTGAGGACGTCCGCGCCGTCGTTCA
TGGCGACAGCCTTATGGTTCCCGGCGGCTTCAATTTTGACGGCGGTCGCATCTCGGCCTTCGATGCCGAGGCCGTGGCCG
GCGCCGCCCGCCAGGCGGTCGCGGCTGGAATCTCGCAGATCGCGGTGTCCTGCATCTTCAGCCAGCTGAACGCAGAACAG
GAAGCCGAAGCCGCCGAGATCATCTCACGCGTAGCGCCGGGCGTGGGCGTCACCCTCTCCTCAGAGCTCGGACGCGCCGG
GCTTCTCGAGCGCGAAAACGCCGCCATCATGAACGCCAGCCTCCGTCCGCTTGCCGCGAAGGTCGCGCGCGCGTTCGGCG
ACGCCCTTATCGGGCTGAAGCTGACCTGTCCCTGGTACGTCAGCCAGAACGACGGCACGCTGATGAGCGCCGATCAGCTC
CGGCGCCATCCCGTGCTGACCTTCGCCGCAGGTCCGACGAACAGCCTTCGCGGCGCGGCCTGGCTCACGGGCCAGGCGAG
CGCGGTGGTGATCGATATCGGCGGCACGACGACCGACGTCGGCGTGCTCGCCAACGGATTTCCGCGTCAGTCCTCGGTGC
ACGTCGATGTTGGCGGCGTCCGCACGAACTTCCGCATGCCTGACATCCTCTCGACAGGCCTGGGCGGCGGCAGCCTGGTG
GTCCGCGACGGCGATCGTGTCTCGGTTGGCCCACGTTCCGTGGGCTACGCCCTCCGCCAGAAGGCGCTCATCTTCGGGGG
CGACACCCTGACGACCAGCGACATCGCGGTCGCTTCCGGCTGGGCGGACTTCGGGGACAAGGCGCGGGTGGCCGGCATAG
ACGAGCCCCTGAAGGCGGCGGCGCGCCAGGAAATCGACCGCCTGATCGCCGAGGCCGTGGACCGCATCAAGACGGCCCCG
GAAGACATGCCTGCGATCCTTGTGGGAGGCGGCGGCATCCTCGTGCGCGAAGCGCCGCCCGGCATTTCCGAACTCTTCCG
TCCCGCGCACGCCGAAGTCGCCAACGCAATCGGCGCTGCGATCGGCCAGGTCAGCGGGGAAGTCGATCGCATCTACTCCG
TGAACTCGCCGGCCGACCGAGAGGCGGCGCTCGCAGACGCTCAGACGCTCGCCCGGCAGAAGGTGCTCGAAGCCGGCGGG
ACCGAAGAGGGCCTCGAGATCGTCGATCTGGAAGCCAACCCCATTCAATACCTGCCCGGAGGGGCGACCCGGGTCATCTG
CCGAGCAGTGAGTGATCTGGCGGCGACGGAGGCTCACCAATGA

Upstream 100 bases:

>100_bases
AGCGACTACCAGGTAGATCCATCCCCCTCCTAAGCGCTGTCGTTGCCCCTCCCCGACGCTTCGTCGCACGACTTGCCGCC
TGCAGAGGATTGGGAAAGTC

Downstream 100 bases:

>100_bases
TCACCCACATCGGCCTGGACGACATCGAAGATCTCGCCATCGGCTCCGCCTTCCTGGGCACCGGCGGCGGCGGCGACCCC
TACCTGGGCTCGCTGCTCTG

Product: N-methylhydantoinase (ATP-hydrolyzing)

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MRIGVDVGGTNTDAALIRGREVVAAVKRPTTADVKSGIIAAIEALILEAEVNAEAIRAVMIGTTHFTNAFVQRRELTRVF
ALRIGAPASRGVPPFSGWPEDVRAVVHGDSLMVPGGFNFDGGRISAFDAEAVAGAARQAVAAGISQIAVSCIFSQLNAEQ
EAEAAEIISRVAPGVGVTLSSELGRAGLLERENAAIMNASLRPLAAKVARAFGDALIGLKLTCPWYVSQNDGTLMSADQL
RRHPVLTFAAGPTNSLRGAAWLTGQASAVVIDIGGTTTDVGVLANGFPRQSSVHVDVGGVRTNFRMPDILSTGLGGGSLV
VRDGDRVSVGPRSVGYALRQKALIFGGDTLTTSDIAVASGWADFGDKARVAGIDEPLKAAARQEIDRLIAEAVDRIKTAP
EDMPAILVGGGGILVREAPPGISELFRPAHAEVANAIGAAIGQVSGEVDRIYSVNSPADREAALADAQTLARQKVLEAGG
TEEGLEIVDLEANPIQYLPGGATRVICRAVSDLAATEAHQ

Sequences:

>Translated_520_residues
MRIGVDVGGTNTDAALIRGREVVAAVKRPTTADVKSGIIAAIEALILEAEVNAEAIRAVMIGTTHFTNAFVQRRELTRVF
ALRIGAPASRGVPPFSGWPEDVRAVVHGDSLMVPGGFNFDGGRISAFDAEAVAGAARQAVAAGISQIAVSCIFSQLNAEQ
EAEAAEIISRVAPGVGVTLSSELGRAGLLERENAAIMNASLRPLAAKVARAFGDALIGLKLTCPWYVSQNDGTLMSADQL
RRHPVLTFAAGPTNSLRGAAWLTGQASAVVIDIGGTTTDVGVLANGFPRQSSVHVDVGGVRTNFRMPDILSTGLGGGSLV
VRDGDRVSVGPRSVGYALRQKALIFGGDTLTTSDIAVASGWADFGDKARVAGIDEPLKAAARQEIDRLIAEAVDRIKTAP
EDMPAILVGGGGILVREAPPGISELFRPAHAEVANAIGAAIGQVSGEVDRIYSVNSPADREAALADAQTLARQKVLEAGG
TEEGLEIVDLEANPIQYLPGGATRVICRAVSDLAATEAHQ
>Mature_520_residues
MRIGVDVGGTNTDAALIRGREVVAAVKRPTTADVKSGIIAAIEALILEAEVNAEAIRAVMIGTTHFTNAFVQRRELTRVF
ALRIGAPASRGVPPFSGWPEDVRAVVHGDSLMVPGGFNFDGGRISAFDAEAVAGAARQAVAAGISQIAVSCIFSQLNAEQ
EAEAAEIISRVAPGVGVTLSSELGRAGLLERENAAIMNASLRPLAAKVARAFGDALIGLKLTCPWYVSQNDGTLMSADQL
RRHPVLTFAAGPTNSLRGAAWLTGQASAVVIDIGGTTTDVGVLANGFPRQSSVHVDVGGVRTNFRMPDILSTGLGGGSLV
VRDGDRVSVGPRSVGYALRQKALIFGGDTLTTSDIAVASGWADFGDKARVAGIDEPLKAAARQEIDRLIAEAVDRIKTAP
EDMPAILVGGGGILVREAPPGISELFRPAHAEVANAIGAAIGQVSGEVDRIYSVNSPADREAALADAQTLARQKVLEAGG
TEEGLEIVDLEANPIQYLPGGATRVICRAVSDLAATEAHQ

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 53862; Mature: 53862

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGVDVGGTNTDAALIRGREVVAAVKRPTTADVKSGIIAAIEALILEAEVNAEAIRAVM
CEEEEECCCCCCCHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHEEEEE
IGTTHFTNAFVQRRELTRVFALRIGAPASRGVPPFSGWPEDVRAVVHGDSLMVPGGFNFD
ECCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHEEECCEEEECCCCCCC
GGRISAFDAEAVAGAARQAVAAGISQIAVSCIFSQLNAEQEAEAAEIISRVAPGVGVTLS
CCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEC
SELGRAGLLERENAAIMNASLRPLAAKVARAFGDALIGLKLTCPWYVSQNDGTLMSADQL
CCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHEEEEEEECCEEEECCCCCEECHHHH
RRHPVLTFAAGPTNSLRGAAWLTGQASAVVIDIGGTTTDVGVLANGFPRQSSVHVDVGGV
HCCCEEEEECCCCCCCCCCEEEECCCCEEEEECCCCCCCHHHHCCCCCCCCEEEEEECCE
RTNFRMPDILSTGLGGGSLVVRDGDRVSVGPRSVGYALRQKALIFGGDTLTTSDIAVASG
EECCCCCHHHHCCCCCCEEEEECCCEEECCCHHHHHHHHHCEEEECCCEEECCCEEEECC
WADFGDKARVAGIDEPLKAAARQEIDRLIAEAVDRIKTAPEDMPAILVGGGGILVREAPP
CCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEECCCC
GISELFRPAHAEVANAIGAAIGQVSGEVDRIYSVNSPADREAALADAQTLARQKVLEAGG
CHHHHHCHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCCC
TEEGLEIVDLEANPIQYLPGGATRVICRAVSDLAATEAHQ
CCCCCEEEEECCCCCEECCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRIGVDVGGTNTDAALIRGREVVAAVKRPTTADVKSGIIAAIEALILEAEVNAEAIRAVM
CEEEEECCCCCCCHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHEEEEE
IGTTHFTNAFVQRRELTRVFALRIGAPASRGVPPFSGWPEDVRAVVHGDSLMVPGGFNFD
ECCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHEEECCEEEECCCCCCC
GGRISAFDAEAVAGAARQAVAAGISQIAVSCIFSQLNAEQEAEAAEIISRVAPGVGVTLS
CCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEC
SELGRAGLLERENAAIMNASLRPLAAKVARAFGDALIGLKLTCPWYVSQNDGTLMSADQL
CCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHEEEEEEECCEEEECCCCCEECHHHH
RRHPVLTFAAGPTNSLRGAAWLTGQASAVVIDIGGTTTDVGVLANGFPRQSSVHVDVGGV
HCCCEEEEECCCCCCCCCCEEEECCCCEEEEECCCCCCCHHHHCCCCCCCCEEEEEECCE
RTNFRMPDILSTGLGGGSLVVRDGDRVSVGPRSVGYALRQKALIFGGDTLTTSDIAVASG
EECCCCCHHHHCCCCCCEEEEECCCEEECCCHHHHHHHHHCEEEECCCEEECCCEEEECC
WADFGDKARVAGIDEPLKAAARQEIDRLIAEAVDRIKTAPEDMPAILVGGGGILVREAPP
CCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEECCCC
GISELFRPAHAEVANAIGAAIGQVSGEVDRIYSVNSPADREAALADAQTLARQKVLEAGG
CHHHHHCHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCCC
TEEGLEIVDLEANPIQYLPGGATRVICRAVSDLAATEAHQ
CCCCCEEEEECCCCCEECCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]