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The map label for this gene is acdA [H]

Identifier: 197105798

GI number: 197105798

Start: 2649727

End: 2650932

Strand: Reverse

Name: acdA [H]

Synonym: PHZ_c2336

Alternate gene names: 197105798

Gene position: 2650932-2649727 (Counterclockwise)

Preceding gene: 197105799

Following gene: 197105797

Centisome position: 66.34

GC content: 66.42

Gene sequence:

>1206_bases
ATGAACCTCGACTTCACGCCTGAAGAGAACGCCTTCCGCGAAGAGGTCCGGGCCTTCATCAAGGAGAACTACCCGGCCGA
ACTGCGCAAGGCGCAGGACGAGCGGCGGCCCCTGACCAAGGAAGAGTATCTCCTGTGGCACAAGGTGCTGGCCAAGAAGG
GCTGGGTCGCGCCGGGCTGGCCAAAGGAGCTGGGCGGCACCGGCTGGACGCCCACCCAGAAGTACATCTGGTCGGAGGAG
ACGGCGAAGGCCGACTGCCTGCCGACCCTGCCGTTCGGCCTCTCGATGCTTGCGCCGGTGCTCTATACGTTCGGCACCGA
CGAGCAGAAGAAGAAGTTCCTGCCGGGCATCTACAACGGCGATGTCTGGTGGTGCCAGGGCTACTCCGAGCCGGGCGCGG
GCTCCGACCTTGCGAACCTGAAGACCCGGGCCGAGCGGATCACCGCCGACGACGGCAAGGAGTACTACATCGTCAACGGC
CAGAAGACGTGGACCACGCTCGGCCAGTACGCCGACTGGGGCTTCTTCCTGGTGCGCACCGATCCCGACGCCAAGCCGCA
GTCGGGCATCTCCTTCCTGCTGATCGACATGAAGACGCCGGGCATCACCGTGCGCCCGATCATCACCCTGGAAGGCGGCC
ACGAGGTCAACGACGTCTTCCTCGACAACGTGAAGGTGCCGGTCGAGAACCGCATCTTCCACGAGAACCAGGGCTGGACC
TGCGCCAAGGCGCTGCTGGCGCACGAGCGCACCGGCATCGCGGGGGTCGCCCGCTCGAAGCGCAACCTTGAGAAGCTGCG
CAAGATCGCCGGCACCGAGCGGTCCGACGCCGGGGGCTCGCTGATCGGCGACGCCTTTTTCCGCCGCAAGGTGGCCGAGC
TGGAGATCGACCTGACGGCCCTGGAGTTCACCGAGCTGCGCACCCTGGCCGGCGAGTCCAGCGGCAAGGGCCCGGGTCCG
GAAAGCTCGATCCTCAAGATCAAGGGCACCGAGATCCAGCAGCGCCTGCAGGAGCTGGCGCTGGAGGCGGTGGGCCACTA
CGGCGCGCCGTTCCTGCGCGACATGACCGGGCACAACCTGGGCATCGGTCCGGACTACGCCGAGGGCCTCGCGGGCGAGT
ACTTCAACGGCCGCAAGACCTCGATCTACGGCGGCTCGAACGAGATCCAGCGCAACATCATCGCCAAGATGGTGCTGGGC
CTCTAA

Upstream 100 bases:

>100_bases
ATCGGTGTTTACGTTGACGTTAGCGTCATCTTTGCAGGCGGCGGAGGCGCGCGTATAGGGTCGCGCGAACCGGCGACGAA
CGCCTGCAAGGGAGATGGCC

Downstream 100 bases:

>100_bases
GCGCCTAAGATATTCACAGATTAGAAGATTTAAGACGGAGCAAGCGCCGTGGATTTCAGCTTCACCGAAGAACAGTCGAT
GCTGCGCGACACGGTCGCGA

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MNLDFTPEENAFREEVRAFIKENYPAELRKAQDERRPLTKEEYLLWHKVLAKKGWVAPGWPKELGGTGWTPTQKYIWSEE
TAKADCLPTLPFGLSMLAPVLYTFGTDEQKKKFLPGIYNGDVWWCQGYSEPGAGSDLANLKTRAERITADDGKEYYIVNG
QKTWTTLGQYADWGFFLVRTDPDAKPQSGISFLLIDMKTPGITVRPIITLEGGHEVNDVFLDNVKVPVENRIFHENQGWT
CAKALLAHERTGIAGVARSKRNLEKLRKIAGTERSDAGGSLIGDAFFRRKVAELEIDLTALEFTELRTLAGESSGKGPGP
ESSILKIKGTEIQQRLQELALEAVGHYGAPFLRDMTGHNLGIGPDYAEGLAGEYFNGRKTSIYGGSNEIQRNIIAKMVLG
L

Sequences:

>Translated_401_residues
MNLDFTPEENAFREEVRAFIKENYPAELRKAQDERRPLTKEEYLLWHKVLAKKGWVAPGWPKELGGTGWTPTQKYIWSEE
TAKADCLPTLPFGLSMLAPVLYTFGTDEQKKKFLPGIYNGDVWWCQGYSEPGAGSDLANLKTRAERITADDGKEYYIVNG
QKTWTTLGQYADWGFFLVRTDPDAKPQSGISFLLIDMKTPGITVRPIITLEGGHEVNDVFLDNVKVPVENRIFHENQGWT
CAKALLAHERTGIAGVARSKRNLEKLRKIAGTERSDAGGSLIGDAFFRRKVAELEIDLTALEFTELRTLAGESSGKGPGP
ESSILKIKGTEIQQRLQELALEAVGHYGAPFLRDMTGHNLGIGPDYAEGLAGEYFNGRKTSIYGGSNEIQRNIIAKMVLG
L
>Mature_401_residues
MNLDFTPEENAFREEVRAFIKENYPAELRKAQDERRPLTKEEYLLWHKVLAKKGWVAPGWPKELGGTGWTPTQKYIWSEE
TAKADCLPTLPFGLSMLAPVLYTFGTDEQKKKFLPGIYNGDVWWCQGYSEPGAGSDLANLKTRAERITADDGKEYYIVNG
QKTWTTLGQYADWGFFLVRTDPDAKPQSGISFLLIDMKTPGITVRPIITLEGGHEVNDVFLDNVKVPVENRIFHENQGWT
CAKALLAHERTGIAGVARSKRNLEKLRKIAGTERSDAGGSLIGDAFFRRKVAELEIDLTALEFTELRTLAGESSGKGPGP
ESSILKIKGTEIQQRLQELALEAVGHYGAPFLRDMTGHNLGIGPDYAEGLAGEYFNGRKTSIYGGSNEIQRNIIAKMVLG
L

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI187960098, Length=409, Percent_Identity=27.8728606356968, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI4557231, Length=409, Percent_Identity=27.8728606356968, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI4501857, Length=404, Percent_Identity=25.4950495049505, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4501859, Length=411, Percent_Identity=28.7104622871046, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI226958412, Length=256, Percent_Identity=27.734375, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI226958414, Length=249, Percent_Identity=27.710843373494, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI4557233, Length=360, Percent_Identity=26.3888888888889, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI48976061, Length=316, Percent_Identity=27.2151898734177, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI211971008, Length=316, Percent_Identity=27.2151898734177, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI76496475, Length=405, Percent_Identity=25.9259259259259, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4557235, Length=405, Percent_Identity=25.9259259259259, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI7656849, Length=344, Percent_Identity=25.5813953488372, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI21361497, Length=234, Percent_Identity=28.2051282051282, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI38505218, Length=357, Percent_Identity=24.9299719887955, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4503943, Length=312, Percent_Identity=25, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87081958, Length=379, Percent_Identity=23.7467018469657, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=408, Percent_Identity=25.2450980392157, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17569725, Length=355, Percent_Identity=27.0422535211268, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17551932, Length=357, Percent_Identity=26.6106442577031, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538396, Length=260, Percent_Identity=28.4615384615385, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17534899, Length=347, Percent_Identity=27.6657060518732, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71985184, Length=204, Percent_Identity=31.8627450980392, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=204, Percent_Identity=31.8627450980392, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17505929, Length=373, Percent_Identity=25.4691689008043, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508101, Length=416, Percent_Identity=24.0384615384615, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17506239, Length=405, Percent_Identity=24.6913580246914, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17534353, Length=350, Percent_Identity=24, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32563615, Length=147, Percent_Identity=34.0136054421769, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71990804, Length=204, Percent_Identity=27.9411764705882, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24660351, Length=304, Percent_Identity=26.3157894736842, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21356377, Length=352, Percent_Identity=25.2840909090909, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24666513, Length=391, Percent_Identity=25.5754475703325, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21355753, Length=237, Percent_Identity=30.8016877637131, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281363737, Length=349, Percent_Identity=25.5014326647564, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24646207, Length=360, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19920834, Length=412, Percent_Identity=23.7864077669903, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 44645; Mature: 44645

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLDFTPEENAFREEVRAFIKENYPAELRKAQDERRPLTKEEYLLWHKVLAKKGWVAPGW
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCC
PKELGGTGWTPTQKYIWSEETAKADCLPTLPFGLSMLAPVLYTFGTDEQKKKFLPGIYNG
HHHHCCCCCCCCHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCC
DVWWCQGYSEPGAGSDLANLKTRAERITADDGKEYYIVNGQKTWTTLGQYADWGFFLVRT
CEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCCCCCCEEEEEE
DPDAKPQSGISFLLIDMKTPGITVRPIITLEGGHEVNDVFLDNVKVPVENRIFHENQGWT
CCCCCCCCCCEEEEEEECCCCEEEEEEEEECCCCCCCCEEECCEECCCCCCEEECCCCCH
CAKALLAHERTGIAGVARSKRNLEKLRKIAGTERSDAGGSLIGDAFFRRKVAELEIDLTA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEEEEH
LEFTELRTLAGESSGKGPGPESSILKIKGTEIQQRLQELALEAVGHYGAPFLRDMTGHNL
HHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCC
GIGPDYAEGLAGEYFNGRKTSIYGGSNEIQRNIIAKMVLGL
CCCCCHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLDFTPEENAFREEVRAFIKENYPAELRKAQDERRPLTKEEYLLWHKVLAKKGWVAPGW
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCC
PKELGGTGWTPTQKYIWSEETAKADCLPTLPFGLSMLAPVLYTFGTDEQKKKFLPGIYNG
HHHHCCCCCCCCHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCC
DVWWCQGYSEPGAGSDLANLKTRAERITADDGKEYYIVNGQKTWTTLGQYADWGFFLVRT
CEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCCCCCCEEEEEE
DPDAKPQSGISFLLIDMKTPGITVRPIITLEGGHEVNDVFLDNVKVPVENRIFHENQGWT
CCCCCCCCCCEEEEEEECCCCEEEEEEEEECCCCCCCCEEECCEECCCCCCEEECCCCCH
CAKALLAHERTGIAGVARSKRNLEKLRKIAGTERSDAGGSLIGDAFFRRKVAELEIDLTA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEEEEH
LEFTELRTLAGESSGKGPGPESSILKIKGTEIQQRLQELALEAVGHYGAPFLRDMTGHNL
HHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCC
GIGPDYAEGLAGEYFNGRKTSIYGGSNEIQRNIIAKMVLGL
CCCCCHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]