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The map label for this gene is divA [H]

Identifier: 197105791

GI number: 197105791

Start: 2642519

End: 2644264

Strand: Reverse

Name: divA [H]

Synonym: PHZ_c2329

Alternate gene names: 197105791

Gene position: 2644264-2642519 (Counterclockwise)

Preceding gene: 197105792

Following gene: 197105790

Centisome position: 66.17

GC content: 73.08

Gene sequence:

>1746_bases
ATGAGCCTGGGCCAGCAGGCCTTCGGCGGCTCGGCCGTCTCGCGCTGGTTCAAGGAGCGCATCTGGGGTCTCGAGCACGC
CTTCGAGCGGGCTCGCGCCTCGGGCCGCGCCGAGGACGACACGCGCCTGCGCATCTTCTTCGTGCTGGTGCTGTTCGTGC
TGGGCTTCGTCTGGCTGTCGGTGGGCGCTACGCGCGCGGCGCTCTTCTCGGACGCCCGGGGCGGCGGCCGCATCGCGCCG
GCCGGAGTCTCCCGCGCCGATCTCGTCGACCGCAACGGCATGCTGCTGGCGGCCGACCTGCTGCACTACGGCCTCTACAT
CGATCCGCGCGAGATCTGGGAGACCGAGGAGACCCGCCGCCAGCTCCTGGCCGCCCTGCCGGGCCTCGACAGGGCGCGCC
TCGAACGCGCCCTGCGCGGCCAGCGCCGCCTGTTCGTGATGGGCGCCCTGACGCCCGCCGAACGCAATCGCGTCCACGCC
CTGGGCCTGCCCGGCGTCAGCTTCGAGCCCGAGCAGCGCCGCGTCTATCCGCTGGGCGCGAGCGCCGCCCACGTCATCGG
CTTCTCAGACACCGGGGGCGAGGGCCTGTCGGGCGCCGAGGCCGCGCTGAACGAGGAGATCCGCGCCGCGGCCGGCGGCC
AGGTCCCCCTGTCCATCGACCTGCGCGTCCAGGGCGCGCTGGAGGACGAGCTGTGGAAGGCCGTCCACGAGTTCACCCCG
AAGGGCGCGGTGGGCCTCGTCACCGACGTGCACACCGGCGAGATCCTGGGGATGGCCAGCTGGCCGACCTTCGACCCGAA
CAAGCCCGGCCAGGCCACCGACTACGTGCGCACCAACCGCGCGGCCGCCTCGGTCTTCGAGATGGGCTCGACGTTCAAGG
CGTTCACCGTCGCCATCGGCCTCGACGCCGGCGTCGCCACTCCGAACACGACCTTCGACGCGCGCGAGCCCTTCAAGCTG
GGCTACCGGACGATCCACGACTACCACGCCGCCCGGAAGGTCCTGACCCTGGTCGAGGTGTTCCAGCACTCGTCCAACAT
CGGCACCGCCAAGCTGGCCGTGGGCATCGGCCCCGAGCGCATGGGCCGTTACTTCGACGGCCTGGGGCTGACCAAGCCCG
CGCCGGTGGAGCTGATCGAGTCCGCGCGGCCCCTGACCCCGCGCAAGTGGGACGAGGACGCGGTGGCCTCCACCTCCTTC
GGCCACGGCATCAACGTCAGCCCGCTGGCGCTCGCCCGGGCCATGGGCGCGATCCTGAACGGCGGGCGCCTCGTGCCGCT
GACCATCCGCAAGCTGGAACCCGGTGCGGCAGTCGACGGTCCCCGGGTGATGTCCGAGCGCACGTCCCTGCAGATGCTGT
CGATCATGCGCGCCAACGTGGCGGGCGAGGCGGGCAGCGGCCGGTCGGCCAACATCCCGGGCCTGTCGGTGGGCGGCAAG
ACCGGCACCGGCGAGAAGTACGATCCTGCGATCCGCGCCTACAACCACGAGCGTCAGGTCTCCTCGTTCGCCGCCGTGTT
CCCCACCAGCGGCCCGGCCGAGGCCAAGCGCTACTTCGTGCTGATCCTGCTGGACGAGCCGCACGGCACCGCCCGCAGCG
CCGGCTACGCCACCGGCGGCTGGGTGGCCGCGCCGGCCGCCGGCCGGGTCATCGAGCGCATCGCCCCGTTCCTGGGCGTC
GAGCGCCAGCCCGAGCTCGCCGAGATCGCGCCCGCGGGCGCCGCGCCGATGGGGGAGGGCCAGTGA

Upstream 100 bases:

>100_bases
CCGCCGTGGCCGCCATGGTGAACGAGAGCGACGCCACCCCCGGCGTGCCGCCGCCCCCGCCGCCGGAAGGCCGCAGCCTC
CGGATCGCCGAGGCCGGGCG

Downstream 100 bases:

>100_bases
AGCGCCTCTCGGCCATCGTGAAGCGCGGCCTGCCGGCGGATCCCGAGATCACCGGCGTCACCGCCGACAGCCGCAAGGTG
CGGGCCGGCACGCTGTTCGC

Product: penicillin-binding protein B

Products: NA

Alternate protein names: PBP-2 [H]

Number of amino acids: Translated: 581; Mature: 580

Protein sequence:

>581_residues
MSLGQQAFGGSAVSRWFKERIWGLEHAFERARASGRAEDDTRLRIFFVLVLFVLGFVWLSVGATRAALFSDARGGGRIAP
AGVSRADLVDRNGMLLAADLLHYGLYIDPREIWETEETRRQLLAALPGLDRARLERALRGQRRLFVMGALTPAERNRVHA
LGLPGVSFEPEQRRVYPLGASAAHVIGFSDTGGEGLSGAEAALNEEIRAAAGGQVPLSIDLRVQGALEDELWKAVHEFTP
KGAVGLVTDVHTGEILGMASWPTFDPNKPGQATDYVRTNRAAASVFEMGSTFKAFTVAIGLDAGVATPNTTFDAREPFKL
GYRTIHDYHAARKVLTLVEVFQHSSNIGTAKLAVGIGPERMGRYFDGLGLTKPAPVELIESARPLTPRKWDEDAVASTSF
GHGINVSPLALARAMGAILNGGRLVPLTIRKLEPGAAVDGPRVMSERTSLQMLSIMRANVAGEAGSGRSANIPGLSVGGK
TGTGEKYDPAIRAYNHERQVSSFAAVFPTSGPAEAKRYFVLILLDEPHGTARSAGYATGGWVAAPAAGRVIERIAPFLGV
ERQPELAEIAPAGAAPMGEGQ

Sequences:

>Translated_581_residues
MSLGQQAFGGSAVSRWFKERIWGLEHAFERARASGRAEDDTRLRIFFVLVLFVLGFVWLSVGATRAALFSDARGGGRIAP
AGVSRADLVDRNGMLLAADLLHYGLYIDPREIWETEETRRQLLAALPGLDRARLERALRGQRRLFVMGALTPAERNRVHA
LGLPGVSFEPEQRRVYPLGASAAHVIGFSDTGGEGLSGAEAALNEEIRAAAGGQVPLSIDLRVQGALEDELWKAVHEFTP
KGAVGLVTDVHTGEILGMASWPTFDPNKPGQATDYVRTNRAAASVFEMGSTFKAFTVAIGLDAGVATPNTTFDAREPFKL
GYRTIHDYHAARKVLTLVEVFQHSSNIGTAKLAVGIGPERMGRYFDGLGLTKPAPVELIESARPLTPRKWDEDAVASTSF
GHGINVSPLALARAMGAILNGGRLVPLTIRKLEPGAAVDGPRVMSERTSLQMLSIMRANVAGEAGSGRSANIPGLSVGGK
TGTGEKYDPAIRAYNHERQVSSFAAVFPTSGPAEAKRYFVLILLDEPHGTARSAGYATGGWVAAPAAGRVIERIAPFLGV
ERQPELAEIAPAGAAPMGEGQ
>Mature_580_residues
SLGQQAFGGSAVSRWFKERIWGLEHAFERARASGRAEDDTRLRIFFVLVLFVLGFVWLSVGATRAALFSDARGGGRIAPA
GVSRADLVDRNGMLLAADLLHYGLYIDPREIWETEETRRQLLAALPGLDRARLERALRGQRRLFVMGALTPAERNRVHAL
GLPGVSFEPEQRRVYPLGASAAHVIGFSDTGGEGLSGAEAALNEEIRAAAGGQVPLSIDLRVQGALEDELWKAVHEFTPK
GAVGLVTDVHTGEILGMASWPTFDPNKPGQATDYVRTNRAAASVFEMGSTFKAFTVAIGLDAGVATPNTTFDAREPFKLG
YRTIHDYHAARKVLTLVEVFQHSSNIGTAKLAVGIGPERMGRYFDGLGLTKPAPVELIESARPLTPRKWDEDAVASTSFG
HGINVSPLALARAMGAILNGGRLVPLTIRKLEPGAAVDGPRVMSERTSLQMLSIMRANVAGEAGSGRSANIPGLSVGGKT
GTGEKYDPAIRAYNHERQVSSFAAVFPTSGPAEAKRYFVLILLDEPHGTARSAGYATGGWVAAPAAGRVIERIAPFLGVE
RQPELAEIAPAGAAPMGEGQ

Specific function: Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=546, Percent_Identity=30.03663003663, Blast_Score=190, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 62027; Mature: 61896

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS00146 BETA_LACTAMASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLGQQAFGGSAVSRWFKERIWGLEHAFERARASGRAEDDTRLRIFFVLVLFVLGFVWLS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
VGATRAALFSDARGGGRIAPAGVSRADLVDRNGMLLAADLLHYGLYIDPREIWETEETRR
HCHHHHHHHHCCCCCCEECCCCCCHHHHHCCCCCEEEEHHHHHCCEECHHHHHCCHHHHH
QLLAALPGLDRARLERALRGQRRLFVMGALTPAERNRVHALGLPGVSFEPEQRRVYPLGA
HHHHHCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCCCEEEECCC
SAAHVIGFSDTGGEGLSGAEAALNEEIRAAAGGQVPLSIDLRVQGALEDELWKAVHEFTP
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHCCC
KGAVGLVTDVHTGEILGMASWPTFDPNKPGQATDYVRTNRAAASVFEMGSTFKAFTVAIG
CCCEEEEEECCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEE
LDAGVATPNTTFDAREPFKLGYRTIHDYHAARKVLTLVEVFQHSSNIGTAKLAVGIGPER
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHH
MGRYFDGLGLTKPAPVELIESARPLTPRKWDEDAVASTSFGHGINVSPLALARAMGAILN
HHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHC
GGRLVPLTIRKLEPGAAVDGPRVMSERTSLQMLSIMRANVAGEAGSGRSANIPGLSVGGK
CCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCC
TGTGEKYDPAIRAYNHERQVSSFAAVFPTSGPAEAKRYFVLILLDEPHGTARSAGYATGG
CCCCCCCCCHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCC
WVAAPAAGRVIERIAPFLGVERQPELAEIAPAGAAPMGEGQ
EEECCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SLGQQAFGGSAVSRWFKERIWGLEHAFERARASGRAEDDTRLRIFFVLVLFVLGFVWLS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
VGATRAALFSDARGGGRIAPAGVSRADLVDRNGMLLAADLLHYGLYIDPREIWETEETRR
HCHHHHHHHHCCCCCCEECCCCCCHHHHHCCCCCEEEEHHHHHCCEECHHHHHCCHHHHH
QLLAALPGLDRARLERALRGQRRLFVMGALTPAERNRVHALGLPGVSFEPEQRRVYPLGA
HHHHHCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCCCEEEECCC
SAAHVIGFSDTGGEGLSGAEAALNEEIRAAAGGQVPLSIDLRVQGALEDELWKAVHEFTP
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHCCC
KGAVGLVTDVHTGEILGMASWPTFDPNKPGQATDYVRTNRAAASVFEMGSTFKAFTVAIG
CCCEEEEEECCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEE
LDAGVATPNTTFDAREPFKLGYRTIHDYHAARKVLTLVEVFQHSSNIGTAKLAVGIGPER
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHH
MGRYFDGLGLTKPAPVELIESARPLTPRKWDEDAVASTSFGHGINVSPLALARAMGAILN
HHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHC
GGRLVPLTIRKLEPGAAVDGPRVMSERTSLQMLSIMRANVAGEAGSGRSANIPGLSVGGK
CCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCC
TGTGEKYDPAIRAYNHERQVSSFAAVFPTSGPAEAKRYFVLILLDEPHGTARSAGYATGG
CCCCCCCCCHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCC
WVAAPAAGRVIERIAPFLGVERQPELAEIAPAGAAPMGEGQ
EEECCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3126399 [H]