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The map label for this gene is gudP [H]

Identifier: 197105720

GI number: 197105720

Start: 2557858

End: 2559162

Strand: Reverse

Name: gudP [H]

Synonym: PHZ_c2258

Alternate gene names: 197105720

Gene position: 2559162-2557858 (Counterclockwise)

Preceding gene: 197105721

Following gene: 197105718

Centisome position: 64.04

GC content: 69.2

Gene sequence:

>1305_bases
ATGAGCGTGGACGCCGTGCCGGCGCCGAAGGTGTCGGCGAGCTATCGCTACATGGTCGTCTGGCTTCTGGCCGTCGTCTA
CACGCTGAACTTCCTGGACCGGCAGATCGTCTCGATCCTGGCCGAGCCGATCCGCAAGGACCTGCAGCTCGACGACACCC
AGCTCGGCATGCTGAGCGGCATCGTCTTTGCGATCTTCTACACCGGCTTCGGCATCCCCGTCGGCTGGCTGGCCGACCGG
GCCCGGCGGGTCTGGATCATCTCGGGAGCGTGCGCGCTGTGGAGCCTGTTCACGGCGCTCTGCGGCACGGCGACCAACTT
CGTCCAGCTCGCGCTCTACCGGATGGGCGTCGGCATCGGCGAGGCGGGCGGCTCCCCGCCGTCCTATTCGCTGATCTCGG
ACTACTTCAAGCCCGAGGAGCGGGGCACGGCGCTCGCGATCTACTCCCTGGGCGTGCCCGCCGGATCGATGTTCGGCTCG
GCGCTGGGCGGCTGGATCGCGGCCGAGCACGGCTGGCGGACGGCGTTCTACGTCATGGGCGTGCCGGGCATCATCCTGGC
GCTCGTCGTGCTGCTGTTCGTCAAGGAGCCGAAGCGCGGCGGCCTCGACAAGATCGCCGACGGCAAGGACGCGCACGACG
CGGCCCCGCCGCTCTGGACGGCGATCGGCGGCTTCTTCTCGAACCGCACGCTGGTGCTGACGGCCTTCGCCGCCGGCCTC
TCGGCCTTCGTCGGCTATGCCGCCCTGACCTGGAACCCGCCGTTCCTGATGCGGGTGAAGGGCATGAGCCTGACCGAAGT
CGCCGCCTACTACAGCCTCGTGCTGGGGATCACCGGCATGATCGGCACGTTCGCGGCCGGCTGGATCGCCGACAAGCTGG
GCGCCAAGGACCGCCGCTGGTTCGCCTGGATCCCGGCCCTGGCGTTCTTCATCACGATCCCGTTCTGGTTCGGCATCGTC
TATGCGCCGACCTGGCAGATCGCCCTGATCTGCATCGCGGTGCCGGCGCTGCTGAACAACTGCTACCTCGCGCCGGCGCT
CGCCGTCGTGCAGAACGCGGTGCCGCCGAACCGGCGCACGATCTCGGGCGCGGTGCTGCTGTTCGTGCTGAACCTGATCG
GCCTGGGCGCGGGGCCGGTCTACGTCGGCCGCATCTCCGACATGGCCAAGGCCGAGCACGGCGACAACTCGCTCTCGATC
GCGTTCCTGGCCCTGGTGCCGGTGATCGTGATCACGATCCTCGCGCACCTGGCGTCCGCCTGGTCGATCGCCCGCGACAA
GCGCCTCGCCGCGGCGGTGGGCTGA

Upstream 100 bases:

>100_bases
TTGGCGTCGCCCGCGGTTGCTGCCAAAACACGGGCAGGAAGCGCATACCCGTTTTTCGAGCCGGAACACCGGCCTGACGG
GCGACAGGGGGAGACAGCGT

Downstream 100 bases:

>100_bases
CCTGGAGCTTGTGGCCTAGAGCCGGTCGAGGGCGGCGCGGAGCCGGCCGCCGACCTCGCGCGCCTTGGCCTTCAGGTCGG
CGTTGTCGATGGCCTGCATC

Product: major facilitator superfamily MFS_1

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MSVDAVPAPKVSASYRYMVVWLLAVVYTLNFLDRQIVSILAEPIRKDLQLDDTQLGMLSGIVFAIFYTGFGIPVGWLADR
ARRVWIISGACALWSLFTALCGTATNFVQLALYRMGVGIGEAGGSPPSYSLISDYFKPEERGTALAIYSLGVPAGSMFGS
ALGGWIAAEHGWRTAFYVMGVPGIILALVVLLFVKEPKRGGLDKIADGKDAHDAAPPLWTAIGGFFSNRTLVLTAFAAGL
SAFVGYAALTWNPPFLMRVKGMSLTEVAAYYSLVLGITGMIGTFAAGWIADKLGAKDRRWFAWIPALAFFITIPFWFGIV
YAPTWQIALICIAVPALLNNCYLAPALAVVQNAVPPNRRTISGAVLLFVLNLIGLGAGPVYVGRISDMAKAEHGDNSLSI
AFLALVPVIVITILAHLASAWSIARDKRLAAAVG

Sequences:

>Translated_434_residues
MSVDAVPAPKVSASYRYMVVWLLAVVYTLNFLDRQIVSILAEPIRKDLQLDDTQLGMLSGIVFAIFYTGFGIPVGWLADR
ARRVWIISGACALWSLFTALCGTATNFVQLALYRMGVGIGEAGGSPPSYSLISDYFKPEERGTALAIYSLGVPAGSMFGS
ALGGWIAAEHGWRTAFYVMGVPGIILALVVLLFVKEPKRGGLDKIADGKDAHDAAPPLWTAIGGFFSNRTLVLTAFAAGL
SAFVGYAALTWNPPFLMRVKGMSLTEVAAYYSLVLGITGMIGTFAAGWIADKLGAKDRRWFAWIPALAFFITIPFWFGIV
YAPTWQIALICIAVPALLNNCYLAPALAVVQNAVPPNRRTISGAVLLFVLNLIGLGAGPVYVGRISDMAKAEHGDNSLSI
AFLALVPVIVITILAHLASAWSIARDKRLAAAVG
>Mature_433_residues
SVDAVPAPKVSASYRYMVVWLLAVVYTLNFLDRQIVSILAEPIRKDLQLDDTQLGMLSGIVFAIFYTGFGIPVGWLADRA
RRVWIISGACALWSLFTALCGTATNFVQLALYRMGVGIGEAGGSPPSYSLISDYFKPEERGTALAIYSLGVPAGSMFGSA
LGGWIAAEHGWRTAFYVMGVPGIILALVVLLFVKEPKRGGLDKIADGKDAHDAAPPLWTAIGGFFSNRTLVLTAFAAGLS
AFVGYAALTWNPPFLMRVKGMSLTEVAAYYSLVLGITGMIGTFAAGWIADKLGAKDRRWFAWIPALAFFITIPFWFGIVY
APTWQIALICIAVPALLNNCYLAPALAVVQNAVPPNRRTISGAVLLFVLNLIGLGAGPVYVGRISDMAKAEHGDNSLSIA
FLALVPVIVITILAHLASAWSIARDKRLAAAVG

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI185136021, Length=427, Percent_Identity=26.9320843091335, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI215490096, Length=397, Percent_Identity=26.1964735516373, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI14042968, Length=397, Percent_Identity=26.1964735516373, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI215490100, Length=385, Percent_Identity=26.2337662337662, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI194239645, Length=460, Percent_Identity=25.4347826086956, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI215490102, Length=380, Percent_Identity=25.2631578947368, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI256219598, Length=300, Percent_Identity=23.6666666666667, Blast_Score=65, Evalue=1e-10,
Organism=Homo sapiens, GI4503847, Length=300, Percent_Identity=23.6666666666667, Blast_Score=65, Evalue=1e-10,
Organism=Homo sapiens, GI256219483, Length=300, Percent_Identity=23.6666666666667, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI1789152, Length=317, Percent_Identity=28.391167192429, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1789515, Length=292, Percent_Identity=27.7397260273973, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI2367379, Length=283, Percent_Identity=29.3286219081272, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082320, Length=396, Percent_Identity=24.2424242424242, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI2367193, Length=262, Percent_Identity=24.4274809160305, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081723, Length=220, Percent_Identity=29.5454545454545, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193209775, Length=459, Percent_Identity=26.1437908496732, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17557872, Length=451, Percent_Identity=24.390243902439, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI71992409, Length=460, Percent_Identity=26.5217391304348, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17539092, Length=459, Percent_Identity=25.4901960784314, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24654041, Length=397, Percent_Identity=27.455919395466, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24654037, Length=397, Percent_Identity=27.455919395466, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24654039, Length=399, Percent_Identity=27.0676691729323, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17864456, Length=399, Percent_Identity=27.0676691729323, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24654044, Length=243, Percent_Identity=30.0411522633745, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24640209, Length=344, Percent_Identity=25.8720930232558, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46426; Mature: 46295

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVDAVPAPKVSASYRYMVVWLLAVVYTLNFLDRQIVSILAEPIRKDLQLDDTQLGMLSG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
IVFAIFYTGFGIPVGWLADRARRVWIISGACALWSLFTALCGTATNFVQLALYRMGVGIG
HHHHHHHHHCCCCHHHHHHCCCEEEEEECHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCC
EAGGSPPSYSLISDYFKPEERGTALAIYSLGVPAGSMFGSALGGWIAAEHGWRTAFYVMG
CCCCCCCCHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECC
VPGIILALVVLLFVKEPKRGGLDKIADGKDAHDAAPPLWTAIGGFFSNRTLVLTAFAAGL
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHH
SAFVGYAALTWNPPFLMRVKGMSLTEVAAYYSLVLGITGMIGTFAAGWIADKLGAKDRRW
HHHHHHHHEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
FAWIPALAFFITIPFWFGIVYAPTWQIALICIAVPALLNNCYLAPALAVVQNAVPPNRRT
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCH
ISGAVLLFVLNLIGLGAGPVYVGRISDMAKAEHGDNSLSIAFLALVPVIVITILAHLASA
HHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WSIARDKRLAAAVG
HHHHHHHHHHHCCC
>Mature Secondary Structure 
SVDAVPAPKVSASYRYMVVWLLAVVYTLNFLDRQIVSILAEPIRKDLQLDDTQLGMLSG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
IVFAIFYTGFGIPVGWLADRARRVWIISGACALWSLFTALCGTATNFVQLALYRMGVGIG
HHHHHHHHHCCCCHHHHHHCCCEEEEEECHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCC
EAGGSPPSYSLISDYFKPEERGTALAIYSLGVPAGSMFGSALGGWIAAEHGWRTAFYVMG
CCCCCCCCHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECC
VPGIILALVVLLFVKEPKRGGLDKIADGKDAHDAAPPLWTAIGGFFSNRTLVLTAFAAGL
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHH
SAFVGYAALTWNPPFLMRVKGMSLTEVAAYYSLVLGITGMIGTFAAGWIADKLGAKDRRW
HHHHHHHHEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
FAWIPALAFFITIPFWFGIVYAPTWQIALICIAVPALLNNCYLAPALAVVQNAVPPNRRT
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCH
ISGAVLLFVLNLIGLGAGPVYVGRISDMAKAEHGDNSLSIAFLALVPVIVITILAHLASA
HHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WSIARDKRLAAAVG
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]