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The map label for this gene is zraS [C]

Identifier: 197105721

GI number: 197105721

Start: 2559280

End: 2561724

Strand: Reverse

Name: zraS [C]

Synonym: PHZ_c2259

Alternate gene names: 197105721

Gene position: 2561724-2559280 (Counterclockwise)

Preceding gene: 197105722

Following gene: 197105720

Centisome position: 64.1

GC content: 71.82

Gene sequence:

>2445_bases
ATGCCTGACGCTGTCGGCCGGGGGCGGGCGCCGGAGGTCTCGGTCCTCCTGCTGGAGGACAGCGAGATCGACGCCGAGCT
GCTGGCGGCCCATCTCGAGAAGGCGGGGATCGAGTTCACGCTGCTGCGGGCCACCAACCGGCGCGAGTTCGTCCATGCGC
TGGAGGAAGAGCGCTGCGACATCATCCTCGCGGACTATTCCCTGCCGGACTTCGACGGCCTGTCGGCGCTGAACATCGCC
CGGGCCCTGCAGCCGGACATCCCATTCATCTTCGTCTCGGGCGTGGTGGGGGAGGAGTTCGCCACCAACGCGCTGAAGCG
CGGGGCGACGGATTATGTGCTGAAGCGCAACCTCACCCGCCTGGCCACGGCGGTCGAGCGGGCCCTGGAGCAGGCGCACG
AGCGGGAGGAGCGCCGGCGGGCCGAGGAGGCGCTCTCGCGCAGCCAGATGCGGGCGCGCCTGGCCATCGAGGGCGCCCGG
CTCGGCCTCTGGGACCTCGACCCGCGGAACGGGCGCCTGGAGTGCGACGCGCGCACGCGCGACTTCCTGGGCCTGCCGGC
CGACGCCGAGATCACCTACAAGCGCTTCCTGAGGCTGGTGCACCCCGACGACCGCGCCACGCTGGAGGCGGAGATCGCCG
GCGCCATCGCGGGCGGCGATGAGCAGGACCGCGCTCTGGTCACCGAGTTCCGCACCGGCCCGGAGGCGGCGGTCGAGCGC
TGGCTCGCGCTCCGCGCCCAGGCGCTGTTCACGGACGAGACCTGCACCCGGTTCGTCGGGGTGCTGCGCGACATCACCGA
GGAACGGCGGGCTCGCCAGGAGCTGAAGGGCTTCGCCGAGAAGCTCGAGCAGGAGGTGGCCGAACGGACCGCCGAACGGG
ACCGGATCTGGCGGCTCAGCCGCGACCTCTTCGCCGTCGCCACCTTCGACGGGCGGCTGCGCCGGGTGAACCCCGCCTGG
GAGTCCGTGCTCGGCTACGACGCCGGGGCCCTGGTCGACAGCGACTTCCACCTCCTGATCCACAAGGAGGATCTGGCGGA
GGTCGAGGGAGTCATCAGGACGCTTGCCAGCGGCCAGGTCGCCCCCCGGTTCGAGGACCGCCTGCGCCACGCGGACGGCT
CCTGGCGCTGGATCTCGTGGACGGCCGTGCCGGAAGGCGACGCCTTCTACGCGGTCGGGCGGGACATCACCGAGGAGAAG
GCGGCGGCCGAAGCCCTCGCCGAGCGGAACGAGCAGCTCGCCGCCCAGATGGCCGAGCGCGAACGGGTCGAAAAGGAGCT
GCGGCAGATGCAGCGCCTGGAGGCCGTGGGCCAGCTCACCTCGGGCGTGGCGCACGACTTCAACAACCTGCTGACCGTCA
TCCTCGGCAACATCCGCTTCATCGAGAGGACGTTGCAGAGGGAGGGGCTCGACGGCGGGGTGGTCGATCGGCTCGGCCAC
ATGCGGAACGCCGCCGAGCGCGGCGCCAAGCTGACCGGCCAGATGCTGGCCTTCTCGCGCCGCCAGAAGCTGGAGCCCAA
GCCCGTCGACCTGAACGACACGGTCGAGAGCATGCGCGAGCTGCTGCAGAGCACGCTCGGCGGCACCGTGCGTCTCGAGA
CGGTGCTCAAGACCGACCTGTGGTCGGCGCTGGTCGACCCGACGCAGATCGAGCTGATCATCCTGAACCTGGCCATCAAC
GCGCGCGATGCGATGGAGGTCGGCGGCAGCCTGACCGTCGAGACGGCGAACGTCATGATCAAGGGCGAACCCGGCCGTCC
CGAAGAGCCGGGGCCGGGCGAGTACGTCATGCTGGCGGTCAGCGACACCGGCCACGGCATGAGCGAAGAGGTCCTGGCCA
AGGCGTTCGAGCCATTTTTCACGACCAAGGCCGTCGGCCGCGGATCCGGCCTGGGCCTGGCCCAGGTCTACGGCTTCGCC
AAGCAGTCCGGCGGCGGCGTCGCCATCCGCACGCGGGAGGGCGAGGGCACGACGGTCAGCGTCTACCTGCCGAGGGCCGC
GGAGGCGCCGGCGCGGCTGCCCGCCCGGCGCGAGGTCGAGGCGCCGGCCGCGCCGGCGGGCGCGACGGTGCTGCTGGTGG
ACGACGACAGCGCCGTGCGCGAGGTCACCGCCTCGCTGCTGCGCGAGTTCGGCTACGGCGTGATCGAGGCCGGCAGCGGC
AATGCGGCGCTCGACGCCCTGCGTGGCGCCGCCCGGATCGACCTGCTGCTCGCCGACTACGCCATGCCCGGGATGAACGG
CGTCGAGACCGTCCGCGAGGCCCAGCGCCTGCGGCCGGGCCTGCCCAGCCTGTTCATCACCGGCTTCGCGGATCTGGCGG
CGCTGCGCGAGGTCGGCGAGGAACGGATCATCCAGAAGCCGTTCCGCGACGACGAACTTGGCCGCAAGGTCGCCGCGATC
CTGGGCGGCGAGCGCGGCGCCAACGTCGTCTCCCTGCGACGCTGA

Upstream 100 bases:

>100_bases
GTGGTGAAGCCCGTGGACTTCAACGCCTTCTTCGAGGCCATCCAGGACCTCGGCATGTTCTGGGCGATCCTCAACGAGCC
GCCGCCGCGGGGGCTGGCCC

Downstream 100 bases:

>100_bases
CGTCCGCGGAAAGCGGCTTGGCGTCGCCCGCGGTTGCTGCCAAAACACGGGCAGGAAGCGCATACCCGTTTTTCGAGCCG
GAACACCGGCCTGACGGGCG

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 814; Mature: 813

Protein sequence:

>814_residues
MPDAVGRGRAPEVSVLLLEDSEIDAELLAAHLEKAGIEFTLLRATNRREFVHALEEERCDIILADYSLPDFDGLSALNIA
RALQPDIPFIFVSGVVGEEFATNALKRGATDYVLKRNLTRLATAVERALEQAHEREERRRAEEALSRSQMRARLAIEGAR
LGLWDLDPRNGRLECDARTRDFLGLPADAEITYKRFLRLVHPDDRATLEAEIAGAIAGGDEQDRALVTEFRTGPEAAVER
WLALRAQALFTDETCTRFVGVLRDITEERRARQELKGFAEKLEQEVAERTAERDRIWRLSRDLFAVATFDGRLRRVNPAW
ESVLGYDAGALVDSDFHLLIHKEDLAEVEGVIRTLASGQVAPRFEDRLRHADGSWRWISWTAVPEGDAFYAVGRDITEEK
AAAEALAERNEQLAAQMAERERVEKELRQMQRLEAVGQLTSGVAHDFNNLLTVILGNIRFIERTLQREGLDGGVVDRLGH
MRNAAERGAKLTGQMLAFSRRQKLEPKPVDLNDTVESMRELLQSTLGGTVRLETVLKTDLWSALVDPTQIELIILNLAIN
ARDAMEVGGSLTVETANVMIKGEPGRPEEPGPGEYVMLAVSDTGHGMSEEVLAKAFEPFFTTKAVGRGSGLGLAQVYGFA
KQSGGGVAIRTREGEGTTVSVYLPRAAEAPARLPARREVEAPAAPAGATVLLVDDDSAVREVTASLLREFGYGVIEAGSG
NAALDALRGAARIDLLLADYAMPGMNGVETVREAQRLRPGLPSLFITGFADLAALREVGEERIIQKPFRDDELGRKVAAI
LGGERGANVVSLRR

Sequences:

>Translated_814_residues
MPDAVGRGRAPEVSVLLLEDSEIDAELLAAHLEKAGIEFTLLRATNRREFVHALEEERCDIILADYSLPDFDGLSALNIA
RALQPDIPFIFVSGVVGEEFATNALKRGATDYVLKRNLTRLATAVERALEQAHEREERRRAEEALSRSQMRARLAIEGAR
LGLWDLDPRNGRLECDARTRDFLGLPADAEITYKRFLRLVHPDDRATLEAEIAGAIAGGDEQDRALVTEFRTGPEAAVER
WLALRAQALFTDETCTRFVGVLRDITEERRARQELKGFAEKLEQEVAERTAERDRIWRLSRDLFAVATFDGRLRRVNPAW
ESVLGYDAGALVDSDFHLLIHKEDLAEVEGVIRTLASGQVAPRFEDRLRHADGSWRWISWTAVPEGDAFYAVGRDITEEK
AAAEALAERNEQLAAQMAERERVEKELRQMQRLEAVGQLTSGVAHDFNNLLTVILGNIRFIERTLQREGLDGGVVDRLGH
MRNAAERGAKLTGQMLAFSRRQKLEPKPVDLNDTVESMRELLQSTLGGTVRLETVLKTDLWSALVDPTQIELIILNLAIN
ARDAMEVGGSLTVETANVMIKGEPGRPEEPGPGEYVMLAVSDTGHGMSEEVLAKAFEPFFTTKAVGRGSGLGLAQVYGFA
KQSGGGVAIRTREGEGTTVSVYLPRAAEAPARLPARREVEAPAAPAGATVLLVDDDSAVREVTASLLREFGYGVIEAGSG
NAALDALRGAARIDLLLADYAMPGMNGVETVREAQRLRPGLPSLFITGFADLAALREVGEERIIQKPFRDDELGRKVAAI
LGGERGANVVSLRR
>Mature_813_residues
PDAVGRGRAPEVSVLLLEDSEIDAELLAAHLEKAGIEFTLLRATNRREFVHALEEERCDIILADYSLPDFDGLSALNIAR
ALQPDIPFIFVSGVVGEEFATNALKRGATDYVLKRNLTRLATAVERALEQAHEREERRRAEEALSRSQMRARLAIEGARL
GLWDLDPRNGRLECDARTRDFLGLPADAEITYKRFLRLVHPDDRATLEAEIAGAIAGGDEQDRALVTEFRTGPEAAVERW
LALRAQALFTDETCTRFVGVLRDITEERRARQELKGFAEKLEQEVAERTAERDRIWRLSRDLFAVATFDGRLRRVNPAWE
SVLGYDAGALVDSDFHLLIHKEDLAEVEGVIRTLASGQVAPRFEDRLRHADGSWRWISWTAVPEGDAFYAVGRDITEEKA
AAEALAERNEQLAAQMAERERVEKELRQMQRLEAVGQLTSGVAHDFNNLLTVILGNIRFIERTLQREGLDGGVVDRLGHM
RNAAERGAKLTGQMLAFSRRQKLEPKPVDLNDTVESMRELLQSTLGGTVRLETVLKTDLWSALVDPTQIELIILNLAINA
RDAMEVGGSLTVETANVMIKGEPGRPEEPGPGEYVMLAVSDTGHGMSEEVLAKAFEPFFTTKAVGRGSGLGLAQVYGFAK
QSGGGVAIRTREGEGTTVSVYLPRAAEAPARLPARREVEAPAAPAGATVLLVDDDSAVREVTASLLREFGYGVIEAGSGN
AALDALRGAARIDLLLADYAMPGMNGVETVREAQRLRPGLPSLFITGFADLAALREVGEERIIQKPFRDDELGRKVAAIL
GGERGANVVSLRR

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=249, Percent_Identity=30.1204819277108, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI87081816, Length=438, Percent_Identity=25.7990867579909, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788549, Length=363, Percent_Identity=25.6198347107438, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI48994928, Length=429, Percent_Identity=26.1072261072261, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=401, Percent_Identity=24.6882793017456, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI145693157, Length=294, Percent_Identity=25.5102040816327, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 89523; Mature: 89391

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDAVGRGRAPEVSVLLLEDSEIDAELLAAHLEKAGIEFTLLRATNRREFVHALEEERCD
CCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCC
IILADYSLPDFDGLSALNIARALQPDIPFIFVSGVVGEEFATNALKRGATDYVLKRNLTR
EEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHH
LATAVERALEQAHEREERRRAEEALSRSQMRARLAIEGARLGLWDLDPRNGRLECDARTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEECEEECCCCCCEEEECCCCC
DFLGLPADAEITYKRFLRLVHPDDRATLEAEIAGAIAGGDEQDRALVTEFRTGPEAAVER
CCCCCCCCCHHHHHHHHHHCCCCCCCEEHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHH
WLALRAQALFTDETCTRFVGVLRDITEERRARQELKGFAEKLEQEVAERTAERDRIWRLS
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDLFAVATFDGRLRRVNPAWESVLGYDAGALVDSDFHLLIHKEDLAEVEGVIRTLASGQV
HHEEEEEECCCCEEECCHHHHHHHCCCCCCEECCCCEEEEEHHHHHHHHHHHHHHHCCCC
APRFEDRLRHADGSWRWISWTAVPEGDAFYAVGRDITEEKAAAEALAERNEQLAAQMAER
CCCHHHHHHCCCCCEEEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ERVEKELRQMQRLEAVGQLTSGVAHDFNNLLTVILGNIRFIERTLQREGLDGGVVDRLGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
MRNAAERGAKLTGQMLAFSRRQKLEPKPVDLNDTVESMRELLQSTLGGTVRLETVLKTDL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHH
WSALVDPTQIELIILNLAINARDAMEVGGSLTVETANVMIKGEPGRPEEPGPGEYVMLAV
HHHHCCCCEEEEEEEEEEECCHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCCEEEEEE
SDTGHGMSEEVLAKAFEPFFTTKAVGRGSGLGLAQVYGFAKQSGGGVAIRTREGEGTTVS
ECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCEEE
VYLPRAAEAPARLPARREVEAPAAPAGATVLLVDDDSAVREVTASLLREFGYGVIEAGSG
EEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCC
NAALDALRGAARIDLLLADYAMPGMNGVETVREAQRLRPGLPSLFITGFADLAALREVGE
CHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
ERIIQKPFRDDELGRKVAAILGGERGANVVSLRR
HHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEECC
>Mature Secondary Structure 
PDAVGRGRAPEVSVLLLEDSEIDAELLAAHLEKAGIEFTLLRATNRREFVHALEEERCD
CCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCC
IILADYSLPDFDGLSALNIARALQPDIPFIFVSGVVGEEFATNALKRGATDYVLKRNLTR
EEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHH
LATAVERALEQAHEREERRRAEEALSRSQMRARLAIEGARLGLWDLDPRNGRLECDARTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEECEEECCCCCCEEEECCCCC
DFLGLPADAEITYKRFLRLVHPDDRATLEAEIAGAIAGGDEQDRALVTEFRTGPEAAVER
CCCCCCCCCHHHHHHHHHHCCCCCCCEEHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHH
WLALRAQALFTDETCTRFVGVLRDITEERRARQELKGFAEKLEQEVAERTAERDRIWRLS
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDLFAVATFDGRLRRVNPAWESVLGYDAGALVDSDFHLLIHKEDLAEVEGVIRTLASGQV
HHEEEEEECCCCEEECCHHHHHHHCCCCCCEECCCCEEEEEHHHHHHHHHHHHHHHCCCC
APRFEDRLRHADGSWRWISWTAVPEGDAFYAVGRDITEEKAAAEALAERNEQLAAQMAER
CCCHHHHHHCCCCCEEEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ERVEKELRQMQRLEAVGQLTSGVAHDFNNLLTVILGNIRFIERTLQREGLDGGVVDRLGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
MRNAAERGAKLTGQMLAFSRRQKLEPKPVDLNDTVESMRELLQSTLGGTVRLETVLKTDL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHH
WSALVDPTQIELIILNLAINARDAMEVGGSLTVETANVMIKGEPGRPEEPGPGEYVMLAV
HHHHCCCCEEEEEEEEEEECCHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCCEEEEEE
SDTGHGMSEEVLAKAFEPFFTTKAVGRGSGLGLAQVYGFAKQSGGGVAIRTREGEGTTVS
ECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCEEE
VYLPRAAEAPARLPARREVEAPAAPAGATVLLVDDDSAVREVTASLLREFGYGVIEAGSG
EEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCC
NAALDALRGAARIDLLLADYAMPGMNGVETVREAQRLRPGLPSLFITGFADLAALREVGE
CHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
ERIIQKPFRDDELGRKVAAILGGERGANVVSLRR
HHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA