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The map label for this gene is ydeN [H]

Identifier: 197105714

GI number: 197105714

Start: 2549732

End: 2551411

Strand: Reverse

Name: ydeN [H]

Synonym: PHZ_c2252

Alternate gene names: 197105714

Gene position: 2551411-2549732 (Counterclockwise)

Preceding gene: 197105715

Following gene: 197105711

Centisome position: 63.85

GC content: 70.36

Gene sequence:

>1680_bases
ATGAAGGCGTGGGCGTGGATCGTGGGCGGCGTCGCCGCGCTGGCCGCCGCCGGGGGCGCGGCCTACGTGAACCGGGCCGA
GATCCTGTCGATGATCGCCCGGGCGCGGATGCCCGACGTGGCGCCGAACCGGCCCGTCGAGTGGGCCCAGGGGCCGGCGA
CGGCGGCCGACGCACCGCGCCCGCCCAACGTGGTGTTCATCCTGGCCGACGACCTCGGCTACAACGACATCACCTTCAAC
GGCGGCGGCGTGGCGGGCGGGGCGGTCCCGACGCCGAACATCGACGCCATCGGCCGGCAGGGCGTGAACTTCGCCAGCGG
CTACGCCGGCAACGCCACCTGCGCACCGTCGCGCGCGGCGATCATGACCGGCCGCTACGCCACCCGCTTCGGCTTCGAGT
TCACCCCCGCGCCGGTCGCCTTCGAGCGGATGGTCGGCACCGAGGCCGAGCCCGGGGCGATCGTGAAGCCTAAGTTCTTC
GCCGACCGCATCAAGGACATGCCGCCCGGCAGCACCGCCCCGACGCCGACGGCGGTGAACGTGCTGAGCATGCCCTCGGA
CGAGGTGACGATCGCCGAGGTGCTGAAGGCCCGCGGCTACCACACCATCCACCTCGGCAAATGGCACCTGGGCGGGGCCG
AGGGCTCGCGGCCCGAGCACCAGGGCTTCGACGAGAGCCTCGGCTTCATCGCCGGCGGCTCGATGTACCTGCCCGAGAAG
CACCCCCAGGTGGTCAACTCCAAGCAGCCCTGGGACGCCATCGACCGGTTCCTGTGGCCGAACCTGCCGTACATGGTCCA
GTTCAACGGCGGCGAGCTGTTCGAGCCGCGCGGCTACATGACCGACTACCTGGCCGAGGAGGCGGTGAAGGCGATCCGGG
CCAACCGCAACCGGCCGTTCTTCCTCTATTTCGCGCCCAATGCGGTCCACACGCCGCTGCAGGCGAAGAAGTCGGACTAC
GACGCCCTGCCGCAGATCGCGGACCACCGGATGCGGGTCTACGCCGCGATGGTGCGCAACCTCGACCATAACGTGGGCCT
GATCCTCCAGGCGCTGAAGGACGAGGGGCTGGACCGGAACACCCTCGTCATCTTCACCACCGACAACGGGGGCGCCGGCT
ACGTCGGCCTGCCTGATCTCAACAAACCCTATCGCGGTTGGAAGTCGACGTTCTTCGAGGGCGGTATCAAGGCGCCGTTC
TTCATGCGCTGGCCGGGCGTGATCCCGGCGGGCTCGCGCTTCCCCTATCCGGTGGGGCACGTGGACATCTTCGCCACGGC
CGCCGCCGCGGCCGGCGCCGAGATCCCGGCCGACCGGACCGTGGACGGGGTCGACCTGCTGCCGCACGTCCAGGGACGGA
CGGCGGGACGGCCGCACCAGACGCTGTTCTGGCGCAGCGGCCAGTACAAGACGGTGCTGGACGGGGACTGGAAGCTCCAG
AGCAACGAGGCGCTGGGCAAGGTCTGGCTGTTCAACCTGGCCGAGGATCCGACCGAGCGGCGCGACCTGTCGAAGGCCGA
GCCGGGGCGGGTGAAGGCCATGCTGGCCCTGATTCGCGAGCAGGACGCCCAGAGCGCCAAGCCGATCTGGCCCTCGCTGC
TGCAGGGGCCGATCCTCGTCGACAAGCCGGGCGGGGCGAAGCAGCAGCCGGGCGACGAGTACGTCCTCTGGGACAACTGA

Upstream 100 bases:

>100_bases
GGTGGGCGCCAAGACCGCCGGCTGAACGGCCTCATTCCAAACTAGCGGCACGAGCAATGTCATTATATGCTGCCGCCCGA
ACCTGACGGGGGAGGGCGCG

Downstream 100 bases:

>100_bases
GCCCGATGCGGCGCCTCCTGCCCCTCGCCGTGGCGGGCCTCCTGGCGGCCGCGTGCCAGAGGACCGAGGCGCCGCGCGCG
TGCCTGGCCGACGCGCCCCT

Product: sulfatase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MKAWAWIVGGVAALAAAGGAAYVNRAEILSMIARARMPDVAPNRPVEWAQGPATAADAPRPPNVVFILADDLGYNDITFN
GGGVAGGAVPTPNIDAIGRQGVNFASGYAGNATCAPSRAAIMTGRYATRFGFEFTPAPVAFERMVGTEAEPGAIVKPKFF
ADRIKDMPPGSTAPTPTAVNVLSMPSDEVTIAEVLKARGYHTIHLGKWHLGGAEGSRPEHQGFDESLGFIAGGSMYLPEK
HPQVVNSKQPWDAIDRFLWPNLPYMVQFNGGELFEPRGYMTDYLAEEAVKAIRANRNRPFFLYFAPNAVHTPLQAKKSDY
DALPQIADHRMRVYAAMVRNLDHNVGLILQALKDEGLDRNTLVIFTTDNGGAGYVGLPDLNKPYRGWKSTFFEGGIKAPF
FMRWPGVIPAGSRFPYPVGHVDIFATAAAAAGAEIPADRTVDGVDLLPHVQGRTAGRPHQTLFWRSGQYKTVLDGDWKLQ
SNEALGKVWLFNLAEDPTERRDLSKAEPGRVKAMLALIREQDAQSAKPIWPSLLQGPILVDKPGGAKQQPGDEYVLWDN

Sequences:

>Translated_559_residues
MKAWAWIVGGVAALAAAGGAAYVNRAEILSMIARARMPDVAPNRPVEWAQGPATAADAPRPPNVVFILADDLGYNDITFN
GGGVAGGAVPTPNIDAIGRQGVNFASGYAGNATCAPSRAAIMTGRYATRFGFEFTPAPVAFERMVGTEAEPGAIVKPKFF
ADRIKDMPPGSTAPTPTAVNVLSMPSDEVTIAEVLKARGYHTIHLGKWHLGGAEGSRPEHQGFDESLGFIAGGSMYLPEK
HPQVVNSKQPWDAIDRFLWPNLPYMVQFNGGELFEPRGYMTDYLAEEAVKAIRANRNRPFFLYFAPNAVHTPLQAKKSDY
DALPQIADHRMRVYAAMVRNLDHNVGLILQALKDEGLDRNTLVIFTTDNGGAGYVGLPDLNKPYRGWKSTFFEGGIKAPF
FMRWPGVIPAGSRFPYPVGHVDIFATAAAAAGAEIPADRTVDGVDLLPHVQGRTAGRPHQTLFWRSGQYKTVLDGDWKLQ
SNEALGKVWLFNLAEDPTERRDLSKAEPGRVKAMLALIREQDAQSAKPIWPSLLQGPILVDKPGGAKQQPGDEYVLWDN
>Mature_559_residues
MKAWAWIVGGVAALAAAGGAAYVNRAEILSMIARARMPDVAPNRPVEWAQGPATAADAPRPPNVVFILADDLGYNDITFN
GGGVAGGAVPTPNIDAIGRQGVNFASGYAGNATCAPSRAAIMTGRYATRFGFEFTPAPVAFERMVGTEAEPGAIVKPKFF
ADRIKDMPPGSTAPTPTAVNVLSMPSDEVTIAEVLKARGYHTIHLGKWHLGGAEGSRPEHQGFDESLGFIAGGSMYLPEK
HPQVVNSKQPWDAIDRFLWPNLPYMVQFNGGELFEPRGYMTDYLAEEAVKAIRANRNRPFFLYFAPNAVHTPLQAKKSDY
DALPQIADHRMRVYAAMVRNLDHNVGLILQALKDEGLDRNTLVIFTTDNGGAGYVGLPDLNKPYRGWKSTFFEGGIKAPF
FMRWPGVIPAGSRFPYPVGHVDIFATAAAAAGAEIPADRTVDGVDLLPHVQGRTAGRPHQTLFWRSGQYKTVLDGDWKLQ
SNEALGKVWLFNLAEDPTERRDLSKAEPGRVKAMLALIREQDAQSAKPIWPSLLQGPILVDKPGGAKQQPGDEYVLWDN

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI4503899, Length=518, Percent_Identity=30.1158301158301, Blast_Score=182, Evalue=1e-45,
Organism=Homo sapiens, GI146229331, Length=492, Percent_Identity=32.1138211382114, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI146229329, Length=492, Percent_Identity=32.1138211382114, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI6005990, Length=492, Percent_Identity=32.1138211382114, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI146229324, Length=492, Percent_Identity=32.1138211382114, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI38569405, Length=541, Percent_Identity=26.4325323475046, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI109389362, Length=537, Percent_Identity=27.9329608938547, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI59797060, Length=524, Percent_Identity=27.0992366412214, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI157266309, Length=474, Percent_Identity=27.6371308016878, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI31742482, Length=467, Percent_Identity=28.2655246252677, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI38569407, Length=400, Percent_Identity=29.75, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI45430057, Length=433, Percent_Identity=29.3302540415704, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI146229327, Length=368, Percent_Identity=33.1521739130435, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI53831991, Length=291, Percent_Identity=30.2405498281787, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI71852584, Length=322, Percent_Identity=26.7080745341615, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI58743319, Length=192, Percent_Identity=35.4166666666667, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI87081924, Length=558, Percent_Identity=26.8817204301075, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1790233, Length=421, Percent_Identity=29.6912114014252, Blast_Score=131, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI115533416, Length=491, Percent_Identity=28.1059063136456, Blast_Score=149, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI115533418, Length=481, Percent_Identity=27.4428274428274, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24666109, Length=438, Percent_Identity=31.7351598173516, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI24666175, Length=407, Percent_Identity=30.2211302211302, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI281363223, Length=396, Percent_Identity=30.5555555555556, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI281366397, Length=526, Percent_Identity=27.3764258555133, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI281366395, Length=526, Percent_Identity=27.3764258555133, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24666163, Length=526, Percent_Identity=27.3764258555133, Blast_Score=150, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: 3.1.6.- [C]

Molecular weight: Translated: 60713; Mature: 60713

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS00523 SULFATASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAWAWIVGGVAALAAAGGAAYVNRAEILSMIARARMPDVAPNRPVEWAQGPATAADAPR
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
PPNVVFILADDLGYNDITFNGGGVAGGAVPTPNIDAIGRQGVNFASGYAGNATCAPSRAA
CCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCE
IMTGRYATRFGFEFTPAPVAFERMVGTEAEPGAIVKPKFFADRIKDMPPGSTAPTPTAVN
EEECCHHHHCCCCCCCCCHHHHHHHCCCCCCCCEECCHHHHHHHHCCCCCCCCCCCCEEE
VLSMPSDEVTIAEVLKARGYHTIHLGKWHLGGAEGSRPEHQGFDESLGFIAGGSMYLPEK
EEECCCCCHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCHHHCCEEECCCEECCCC
HPQVVNSKQPWDAIDRFLWPNLPYMVQFNGGELFEPRGYMTDYLAEEAVKAIRANRNRPF
CCHHCCCCCCHHHHHHHHCCCCCEEEEECCCCEECCCCHHHHHHHHHHHHHHHCCCCCCE
FLYFAPNAVHTPLQAKKSDYDALPQIADHRMRVYAAMVRNLDHNVGLILQALKDEGLDRN
EEEECCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
TLVIFTTDNGGAGYVGLPDLNKPYRGWKSTFFEGGIKAPFFMRWPGVIPAGSRFPYPVGH
EEEEEEECCCCCCEEECCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCC
VDIFATAAAAAGAEIPADRTVDGVDLLPHVQGRTAGRPHQTLFWRSGQYKTVLDGDWKLQ
HHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCEEEEECCCEEEEECCCEEEC
SNEALGKVWLFNLAEDPTERRDLSKAEPGRVKAMLALIREQDAQSAKPIWPSLLQGPILV
CCCCCCEEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCEEE
DKPGGAKQQPGDEYVLWDN
ECCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MKAWAWIVGGVAALAAAGGAAYVNRAEILSMIARARMPDVAPNRPVEWAQGPATAADAPR
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
PPNVVFILADDLGYNDITFNGGGVAGGAVPTPNIDAIGRQGVNFASGYAGNATCAPSRAA
CCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCE
IMTGRYATRFGFEFTPAPVAFERMVGTEAEPGAIVKPKFFADRIKDMPPGSTAPTPTAVN
EEECCHHHHCCCCCCCCCHHHHHHHCCCCCCCCEECCHHHHHHHHCCCCCCCCCCCCEEE
VLSMPSDEVTIAEVLKARGYHTIHLGKWHLGGAEGSRPEHQGFDESLGFIAGGSMYLPEK
EEECCCCCHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCHHHCCEEECCCEECCCC
HPQVVNSKQPWDAIDRFLWPNLPYMVQFNGGELFEPRGYMTDYLAEEAVKAIRANRNRPF
CCHHCCCCCCHHHHHHHHCCCCCEEEEECCCCEECCCCHHHHHHHHHHHHHHHCCCCCCE
FLYFAPNAVHTPLQAKKSDYDALPQIADHRMRVYAAMVRNLDHNVGLILQALKDEGLDRN
EEEECCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
TLVIFTTDNGGAGYVGLPDLNKPYRGWKSTFFEGGIKAPFFMRWPGVIPAGSRFPYPVGH
EEEEEEECCCCCCEEECCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCC
VDIFATAAAAAGAEIPADRTVDGVDLLPHVQGRTAGRPHQTLFWRSGQYKTVLDGDWKLQ
HHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCEEEEECCCEEEEECCCEEEC
SNEALGKVWLFNLAEDPTERRDLSKAEPGRVKAMLALIREQDAQSAKPIWPSLLQGPILV
CCCCCCEEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCEEE
DKPGGAKQQPGDEYVLWDN
ECCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]