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The map label for this gene is rnz [H]

Identifier: 197105711

GI number: 197105711

Start: 2546208

End: 2547296

Strand: Reverse

Name: rnz [H]

Synonym: PHZ_c2249

Alternate gene names: 197105711

Gene position: 2547296-2546208 (Counterclockwise)

Preceding gene: 197105714

Following gene: 197105710

Centisome position: 63.74

GC content: 73.0

Gene sequence:

>1089_bases
ATGGGGCGGTGGCGGACGATCGGGCTGATGCTGCTGGCGGCGGTGCTGGCGATCGGGGCGGGGCTCTGGCTGCTGCGGGG
CCAGATCGCCCTGGCGGCGATGCAGCGCATCTACGACCGGGCTCTGGTCGCGGATCCGTACGAGGGCCTGGAGGACGGGC
TGCACGTCGGCCTCTGCGGCGCAGGCTCGCCGATGCCCGACCCGACGCGGGCCGGGCCCTGCACGGCCGTGCTGGCGGGC
CGGCAGCTCTTCATCGTCGATGCGGGCGCAGGGTCGGTGAAGAACCTCTCGCTGATGAACTTCCCGCCCGCGCGGGTGGA
CGCGGCGCTGATCACCCATTTCCACTCGGACCACATCGACGGCCTGGGCGAACTGATGCTCCAGCGCTGGGCCGGCGGCG
CCTGGCCGGCGCCCCTGCCGGTCTACGGCCCCACCGGAGTCGAGCAGGTCGTGGACGGCTTCGAGGCGGCCTATGGGCCC
GATCGCGGCTACCGCATCGCCCACCACGGGCCTCAGGTCACGCCGCCGTCGGGCTTCGGCGGCGATCCGCGTCCCTTCGC
GCCGGGCGCTCAGGACGTCGTGCTCATCGATCAGCCCGGGCTCCGGGTGACGGCCTTCCCGGTCCCGCATTCGCCTGCCG
AGCCGGCGGTGGGCTACCGGTTCGACTACAAGGGCCGCAGCGTGGTGATCAGCGGCGACACCGCCGCCTCTCCGCGCCTG
GAGGCGGCGGCGCGGGGCGCGGACCTGCTGGTGCACGAGGGCCTCTCGCCGAAGCTGGTGGCGCTGCAGGGCCGGTCGGC
GGACAAGGGCGGCAAGGCGAACCTCTCGCACATCCTGCACGACATCCCGAGCTATCACGCCACGCCCGAGGAGGTGGCGG
GGATCGCACAGCGGGCCGGGGTCCGCTACCTGCTGTTCACCCACGTCATTCCGCCGCTGCCGATCCGCGCCCTGGAGGGG
CCCTGGCTGGGGAAGGCCGGGAAGATCTATGCTGGGGCCATCCGCGTCGGCCGTGACGGCGACACCATCAGCCTGCCCGC
GGGCTCGACGGCGATCCGCCGGACCAATCGGCTGAACGTCCTGTTCTGA

Upstream 100 bases:

>100_bases
CGCCGCATCTCCCCGATCTTGCTCTTGATCCAGATAGTGACATTATGCGTGTCATTATGAGCGGCGGCCGTCAAGCCGCC
CGGGAGACGGGAGGACGGCC

Downstream 100 bases:

>100_bases
AGGGGAAAGGGGCATGACCGAGACCGCGCCGATCGCGCTGATGGGGGCGCCGGGTTCCCCGTACACCCGCAAGATGCTGG
CCGTGCTGCGCTACCGGCGG

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MGRWRTIGLMLLAAVLAIGAGLWLLRGQIALAAMQRIYDRALVADPYEGLEDGLHVGLCGAGSPMPDPTRAGPCTAVLAG
RQLFIVDAGAGSVKNLSLMNFPPARVDAALITHFHSDHIDGLGELMLQRWAGGAWPAPLPVYGPTGVEQVVDGFEAAYGP
DRGYRIAHHGPQVTPPSGFGGDPRPFAPGAQDVVLIDQPGLRVTAFPVPHSPAEPAVGYRFDYKGRSVVISGDTAASPRL
EAAARGADLLVHEGLSPKLVALQGRSADKGGKANLSHILHDIPSYHATPEEVAGIAQRAGVRYLLFTHVIPPLPIRALEG
PWLGKAGKIYAGAIRVGRDGDTISLPAGSTAIRRTNRLNVLF

Sequences:

>Translated_362_residues
MGRWRTIGLMLLAAVLAIGAGLWLLRGQIALAAMQRIYDRALVADPYEGLEDGLHVGLCGAGSPMPDPTRAGPCTAVLAG
RQLFIVDAGAGSVKNLSLMNFPPARVDAALITHFHSDHIDGLGELMLQRWAGGAWPAPLPVYGPTGVEQVVDGFEAAYGP
DRGYRIAHHGPQVTPPSGFGGDPRPFAPGAQDVVLIDQPGLRVTAFPVPHSPAEPAVGYRFDYKGRSVVISGDTAASPRL
EAAARGADLLVHEGLSPKLVALQGRSADKGGKANLSHILHDIPSYHATPEEVAGIAQRAGVRYLLFTHVIPPLPIRALEG
PWLGKAGKIYAGAIRVGRDGDTISLPAGSTAIRRTNRLNVLF
>Mature_361_residues
GRWRTIGLMLLAAVLAIGAGLWLLRGQIALAAMQRIYDRALVADPYEGLEDGLHVGLCGAGSPMPDPTRAGPCTAVLAGR
QLFIVDAGAGSVKNLSLMNFPPARVDAALITHFHSDHIDGLGELMLQRWAGGAWPAPLPVYGPTGVEQVVDGFEAAYGPD
RGYRIAHHGPQVTPPSGFGGDPRPFAPGAQDVVLIDQPGLRVTAFPVPHSPAEPAVGYRFDYKGRSVVISGDTAASPRLE
AAARGADLLVHEGLSPKLVALQGRSADKGGKANLSHILHDIPSYHATPEEVAGIAQRAGVRYLLFTHVIPPLPIRALEGP
WLGKAGKIYAGAIRVGRDGDTISLPAGSTAIRRTNRLNVLF

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 38129; Mature: 37998

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRWRTIGLMLLAAVLAIGAGLWLLRGQIALAAMQRIYDRALVADPYEGLEDGLHVGLCG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEEC
AGSPMPDPTRAGPCTAVLAGRQLFIVDAGAGSVKNLSLMNFPPARVDAALITHFHSDHID
CCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHH
GLGELMLQRWAGGAWPAPLPVYGPTGVEQVVDGFEAAYGPDRGYRIAHHGPQVTPPSGFG
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCC
GDPRPFAPGAQDVVLIDQPGLRVTAFPVPHSPAEPAVGYRFDYKGRSVVISGDTAASPRL
CCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCH
EAAARGADLLVHEGLSPKLVALQGRSADKGGKANLSHILHDIPSYHATPEEVAGIAQRAG
HHHHCCCEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCC
VRYLLFTHVIPPLPIRALEGPWLGKAGKIYAGAIRVGRDGDTISLPAGSTAIRRTNRLNV
CEEEEHHHCCCCCCCEECCCCCCCCCCCEEEEEEEECCCCCEEECCCCCHHHHHCCCEEE
LF
EC
>Mature Secondary Structure 
GRWRTIGLMLLAAVLAIGAGLWLLRGQIALAAMQRIYDRALVADPYEGLEDGLHVGLCG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEEC
AGSPMPDPTRAGPCTAVLAGRQLFIVDAGAGSVKNLSLMNFPPARVDAALITHFHSDHID
CCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHH
GLGELMLQRWAGGAWPAPLPVYGPTGVEQVVDGFEAAYGPDRGYRIAHHGPQVTPPSGFG
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCC
GDPRPFAPGAQDVVLIDQPGLRVTAFPVPHSPAEPAVGYRFDYKGRSVVISGDTAASPRL
CCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCH
EAAARGADLLVHEGLSPKLVALQGRSADKGGKANLSHILHDIPSYHATPEEVAGIAQRAG
HHHHCCCEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCC
VRYLLFTHVIPPLPIRALEGPWLGKAGKIYAGAIRVGRDGDTISLPAGSTAIRRTNRLNV
CEEEEHHHCCCCCCCEECCCCCCCCCCCEEEEEEEECCCCCEEECCCCCHHHHHCCCEEE
LF
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]