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The map label for this gene is galE [C]

Identifier: 197105552

GI number: 197105552

Start: 2341732

End: 2342844

Strand: Reverse

Name: galE [C]

Synonym: PHZ_c2089

Alternate gene names: 197105552

Gene position: 2342844-2341732 (Counterclockwise)

Preceding gene: 197105558

Following gene: 197105551

Centisome position: 58.63

GC content: 71.43

Gene sequence:

>1113_bases
ATGAGCAAGACCATCCTGATCACCGGCGGCGCCGGGTTCATCGGCCGTCACGTGGCCCAGGCGCTGCTGGCGCGGGGCGA
CCGCGTCCGCATCCTCGACAGCCTCATCGAGCAGGTCCACCCCACCCGCGCCCGTCCGGCCGAACTGGCCGCGGACGCCG
AGCTGATCGTCGGCGACGTCCGCGACGAGGCCGCCGTGCTGAAGGCGCTGTCCGGCGTGGACCAGGTTGTCCACCTGGCG
GCCGAGGTCGGCGTGGGCCAGAGCATGTACGCGGTCGACCGCTACACCTCTGTCAACGACTACGGCACGGCCGTCCTCTT
CCAGCAGCTCATCGACAATCCGGTCGAGCGGGTCGTCGTGGCCTCGTCCATGTCGATCTACGGGGAGGGGCTCTATCGCA
CCGCCGACGGCGAGTTGCGGGACGACGTGATCCGCGGGGGGCGCAATCCGGACGGCTCGTGGGATCCGCTGGACGAGCAG
GGCAGGCCGATGACCCCGGTCCACACGCCCGAGACCAAGGCCGGCGGGCTGAAGTCGGTCTACGCCATCGGCAAGTTCGT
GCAGGAGCGGCTGACGCTCACCCTCACGCAGCAGTACGGCATGGGCGGCTCGGCCCTGCGGCTCTGGAACGCCTACGGGC
CCGGCCAGGCGCTGTCGAACCCCTACACCGGCGTGCTCGCCATCTTCGCCTCGCGGATCGCCAACGGCCAGGCGCCGATG
GTCTTCGAGGACGGCCAGCAGCGGCGCGACTTCGTCCATGTCCGCGACGTGGCGCGGGCCTTCCTGCTCGCCCTGGACAA
CCCGCGGGCCGACGGAGAGGTGTTCAACATCGGCTCGGGCGTCGATCGCACGGTCGAGGAGGTGGCGCTTCTGCAGGCCA
AGGCCATGGGCCGCCCCGACCTGACGCCCGAGATCGCCGGGAAGGCGCGGGCGGGCGACATCCGCCACTGCATCCCCGAC
CTGGCCAAGGCCCGCGACGTGCTGGGCTACGAGGCCCGGGAGGACTTCGCCGAAGGCCTCGCCGAGCTCGCCGAGTGGGT
CGCCCGCCAGGAGGCCGAGGACCGCGTCGTCGAGGCGCGGCGCGAACTCGAAATGCGCGGGCTGGTCGCATGA

Upstream 100 bases:

>100_bases
GAAGGAACAGCGCCGCGGCCGAACCTCTTCCTCCACCTGCAAGGACCTGCGGCGCCCGGCCCGGGCCGCGCCGAAATCCT
GGACGCGGAGTAGGCCGTAT

Downstream 100 bases:

>100_bases
GGGCGCTCGTCACAGGCGGGGCGGGCTTCATCGGCGCCAACCTGGCCGACCGGCTGGCGTCCGAGGGCTGCGAGGTCGTG
GTCTTCGATGCGCTGGCGCG

Product: Nucleoside-diphosphate-sugar epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSKTILITGGAGFIGRHVAQALLARGDRVRILDSLIEQVHPTRARPAELAADAELIVGDVRDEAAVLKALSGVDQVVHLA
AEVGVGQSMYAVDRYTSVNDYGTAVLFQQLIDNPVERVVVASSMSIYGEGLYRTADGELRDDVIRGGRNPDGSWDPLDEQ
GRPMTPVHTPETKAGGLKSVYAIGKFVQERLTLTLTQQYGMGGSALRLWNAYGPGQALSNPYTGVLAIFASRIANGQAPM
VFEDGQQRRDFVHVRDVARAFLLALDNPRADGEVFNIGSGVDRTVEEVALLQAKAMGRPDLTPEIAGKARAGDIRHCIPD
LAKARDVLGYEAREDFAEGLAELAEWVARQEAEDRVVEARRELEMRGLVA

Sequences:

>Translated_370_residues
MSKTILITGGAGFIGRHVAQALLARGDRVRILDSLIEQVHPTRARPAELAADAELIVGDVRDEAAVLKALSGVDQVVHLA
AEVGVGQSMYAVDRYTSVNDYGTAVLFQQLIDNPVERVVVASSMSIYGEGLYRTADGELRDDVIRGGRNPDGSWDPLDEQ
GRPMTPVHTPETKAGGLKSVYAIGKFVQERLTLTLTQQYGMGGSALRLWNAYGPGQALSNPYTGVLAIFASRIANGQAPM
VFEDGQQRRDFVHVRDVARAFLLALDNPRADGEVFNIGSGVDRTVEEVALLQAKAMGRPDLTPEIAGKARAGDIRHCIPD
LAKARDVLGYEAREDFAEGLAELAEWVARQEAEDRVVEARRELEMRGLVA
>Mature_369_residues
SKTILITGGAGFIGRHVAQALLARGDRVRILDSLIEQVHPTRARPAELAADAELIVGDVRDEAAVLKALSGVDQVVHLAA
EVGVGQSMYAVDRYTSVNDYGTAVLFQQLIDNPVERVVVASSMSIYGEGLYRTADGELRDDVIRGGRNPDGSWDPLDEQG
RPMTPVHTPETKAGGLKSVYAIGKFVQERLTLTLTQQYGMGGSALRLWNAYGPGQALSNPYTGVLAIFASRIANGQAPMV
FEDGQQRRDFVHVRDVARAFLLALDNPRADGEVFNIGSGVDRTVEEVALLQAKAMGRPDLTPEIAGKARAGDIRHCIPDL
AKARDVLGYEAREDFAEGLAELAEWVARQEAEDRVVEARRELEMRGLVA

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI7657641, Length=356, Percent_Identity=24.7191011235955, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI42516563, Length=355, Percent_Identity=26.4788732394366, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI56237023, Length=386, Percent_Identity=25.9067357512953, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI56118217, Length=386, Percent_Identity=25.9067357512953, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI189083684, Length=386, Percent_Identity=25.9067357512953, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI239745448, Length=270, Percent_Identity=26.2962962962963, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI310132178, Length=270, Percent_Identity=26.2962962962963, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI310113012, Length=270, Percent_Identity=26.2962962962963, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=390, Percent_Identity=26.1538461538462, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21356223, Length=361, Percent_Identity=24.3767313019391, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 40100; Mature: 39969

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTILITGGAGFIGRHVAQALLARGDRVRILDSLIEQVHPTRARPAELAADAELIVGDV
CCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHCCCHHEEECC
RDEAAVLKALSGVDQVVHLAAEVGVGQSMYAVDRYTSVNDYGTAVLFQQLIDNPVERVVV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHH
ASSMSIYGEGLYRTADGELRDDVIRGGRNPDGSWDPLDEQGRPMTPVHTPETKAGGLKSV
HHHHHHHCCCCEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
YAIGKFVQERLTLTLTQQYGMGGSALRLWNAYGPGQALSNPYTGVLAIFASRIANGQAPM
HHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHCCCHHHHHHHHHHHHCCCCCCE
VFEDGQQRRDFVHVRDVARAFLLALDNPRADGEVFNIGSGVDRTVEEVALLQAKAMGRPD
EECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCC
LTPEIAGKARAGDIRHCIPDLAKARDVLGYEAREDFAEGLAELAEWVARQEAEDRVVEAR
CCHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RELEMRGLVA
HHHHHHCCCC
>Mature Secondary Structure 
SKTILITGGAGFIGRHVAQALLARGDRVRILDSLIEQVHPTRARPAELAADAELIVGDV
CCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHCCCHHEEECC
RDEAAVLKALSGVDQVVHLAAEVGVGQSMYAVDRYTSVNDYGTAVLFQQLIDNPVERVVV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHH
ASSMSIYGEGLYRTADGELRDDVIRGGRNPDGSWDPLDEQGRPMTPVHTPETKAGGLKSV
HHHHHHHCCCCEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
YAIGKFVQERLTLTLTQQYGMGGSALRLWNAYGPGQALSNPYTGVLAIFASRIANGQAPM
HHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHCCCHHHHHHHHHHHHCCCCCCE
VFEDGQQRRDFVHVRDVARAFLLALDNPRADGEVFNIGSGVDRTVEEVALLQAKAMGRPD
EECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCC
LTPEIAGKARAGDIRHCIPDLAKARDVLGYEAREDFAEGLAELAEWVARQEAEDRVVEAR
CCHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RELEMRGLVA
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]