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The map label for this gene is rfbE [H]

Identifier: 197105551

GI number: 197105551

Start: 2340689

End: 2341810

Strand: Reverse

Name: rfbE [H]

Synonym: PHZ_c2088

Alternate gene names: 197105551

Gene position: 2341810-2340689 (Counterclockwise)

Preceding gene: 197105552

Following gene: 197105550

Centisome position: 58.6

GC content: 73.08

Gene sequence:

>1122_bases
GTGGGTCGCCCGCCAGGAGGCCGAGGACCGCGTCGTCGAGGCGCGGCGCGAACTCGAAATGCGCGGGCTGGTCGCATGAG
GGCGCTCGTCACAGGCGGGGCGGGCTTCATCGGCGCCAACCTGGCCGACCGGCTGGCGTCCGAGGGCTGCGAGGTCGTGG
TCTTCGATGCGCTGGCGCGGCCCGGGGTCGAGCGGAACCTCGCCTGGCTGAAGGCCCGGCACGGCCGCAAGATCACCAGC
GTCCAGGCCGACGTGCGGGACGCCCGCGCCGTCGCCGAGGCGGCCCGGGACGTCCAGGTGATCTTCCACCTGGCGGCCCA
GGTGGCGGTGACCACCAGCCTCGTGCAGCCCATGGACGACTTCGAGATCAACGTCCGCGGCGCGCTGAACGTGCTGGAGG
CGGCGCGCAGGCGCCGCACGCCGGTGATCTTCGCCAGCACGAACAAGGTCTACGGCGACCTGGCGGACGTTCCGCTGGAG
CTCGCGGGCGAGGCCTATCGTCCCAAGGATGCGGACCTGCGCGCGCGGGGCGTCTCCGAGGCCCGGCCGCTGGACTTCCA
CACGCCCTACGGCTGCTCCAAGGGGGCGGCCGACCAGTACGTGCTGGACTACGCCCGCAGCTTCGACCTGCCCACCTGCG
TCCTGCGGATGAGCTGCATCTACGGCCCGCGCCAGATGGGCACCGAGGACCAGGGCTGGGTCGCCCACTTCCTGATCCGC
GCCCTGGAGGGACAGCCCATCGTCGTCTACGGCGACGGCCGGCAGGTGCGCGACATCATGCATGTCGGCGATACGGTGGA
CGCCTACATGGCCGCCTGGCGGCGCATCGAGGAGGTCGCCGGTCGCGCCTTCAACCTGGGCGGCGGCCCCGGCAATGCGG
TGAGCCTGCTGCAGCTGCTGGGCTACATCGAGGAGGTGATCGGCCGGAAGGTCGAGGTCGGGTTCTCGGACTGGCGCGCC
GGCGACCAGCGCTACTACGTCTCGGATCCGTCCGCGGCCAAGCAGGCGCTGCAGCTCGCCGATCCGCGCGACTGGCGCGC
AGGCGTCGCCGACCTCGCCCGGTGGCTGGCGGCCGAGCGCGGACCGGCCGGGACGGCGCGCCGCCCCGTCGAGGCCGCCT
GA

Upstream 100 bases:

>100_bases
GCGACATCCGCCACTGCATCCCCGACCTGGCCAAGGCCCGCGACGTGCTGGGCTACGAGGCCCGGGAGGACTTCGCCGAA
GGCCTCGCCGAGCTCGCCGA

Downstream 100 bases:

>100_bases
TGCGGGTGCTGATGACGGCCGACGCCGTCGGCGGCGTCTGGACCTACGCCCTGGATCTTGCGGCCGGCCTCGCCGGCGCC
GGCGTGCGCACCACGCTGGT

Product: Nucleoside-diphosphate-sugar epimerase

Products: NA

Alternate protein names: CDP-tyvelose 2-epimerase [H]

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MGRPPGGRGPRRRGAARTRNARAGRMRALVTGGAGFIGANLADRLASEGCEVVVFDALARPGVERNLAWLKARHGRKITS
VQADVRDARAVAEAARDVQVIFHLAAQVAVTTSLVQPMDDFEINVRGALNVLEAARRRRTPVIFASTNKVYGDLADVPLE
LAGEAYRPKDADLRARGVSEARPLDFHTPYGCSKGAADQYVLDYARSFDLPTCVLRMSCIYGPRQMGTEDQGWVAHFLIR
ALEGQPIVVYGDGRQVRDIMHVGDTVDAYMAAWRRIEEVAGRAFNLGGGPGNAVSLLQLLGYIEEVIGRKVEVGFSDWRA
GDQRYYVSDPSAAKQALQLADPRDWRAGVADLARWLAAERGPAGTARRPVEAA

Sequences:

>Translated_373_residues
MGRPPGGRGPRRRGAARTRNARAGRMRALVTGGAGFIGANLADRLASEGCEVVVFDALARPGVERNLAWLKARHGRKITS
VQADVRDARAVAEAARDVQVIFHLAAQVAVTTSLVQPMDDFEINVRGALNVLEAARRRRTPVIFASTNKVYGDLADVPLE
LAGEAYRPKDADLRARGVSEARPLDFHTPYGCSKGAADQYVLDYARSFDLPTCVLRMSCIYGPRQMGTEDQGWVAHFLIR
ALEGQPIVVYGDGRQVRDIMHVGDTVDAYMAAWRRIEEVAGRAFNLGGGPGNAVSLLQLLGYIEEVIGRKVEVGFSDWRA
GDQRYYVSDPSAAKQALQLADPRDWRAGVADLARWLAAERGPAGTARRPVEAA
>Mature_372_residues
GRPPGGRGPRRRGAARTRNARAGRMRALVTGGAGFIGANLADRLASEGCEVVVFDALARPGVERNLAWLKARHGRKITSV
QADVRDARAVAEAARDVQVIFHLAAQVAVTTSLVQPMDDFEINVRGALNVLEAARRRRTPVIFASTNKVYGDLADVPLEL
AGEAYRPKDADLRARGVSEARPLDFHTPYGCSKGAADQYVLDYARSFDLPTCVLRMSCIYGPRQMGTEDQGWVAHFLIRA
LEGQPIVVYGDGRQVRDIMHVGDTVDAYMAAWRRIEEVAGRAFNLGGGPGNAVSLLQLLGYIEEVIGRKVEVGFSDWRAG
DQRYYVSDPSAAKQALQLADPRDWRAGVADLARWLAAERGPAGTARRPVEAA

Specific function: Catalyzes the isomeration of CDP-paratose to CDP- tyvelose [H]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=314, Percent_Identity=28.0254777070064, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI7657641, Length=340, Percent_Identity=24.7058823529412, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI56237023, Length=366, Percent_Identity=26.775956284153, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI56118217, Length=366, Percent_Identity=26.775956284153, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI189083684, Length=366, Percent_Identity=26.775956284153, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI310132178, Length=315, Percent_Identity=28.2539682539683, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI310113012, Length=315, Percent_Identity=28.2539682539683, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI239745448, Length=315, Percent_Identity=28.2539682539683, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI116268111, Length=267, Percent_Identity=28.8389513108614, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1788353, Length=349, Percent_Identity=28.3667621776504, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786974, Length=364, Percent_Identity=27.1978021978022, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI48994969, Length=276, Percent_Identity=29.3478260869565, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71982035, Length=365, Percent_Identity=26.3013698630137, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71982038, Length=367, Percent_Identity=26.158038147139, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17568069, Length=328, Percent_Identity=24.6951219512195, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI115532424, Length=268, Percent_Identity=26.1194029850746, Blast_Score=74, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=369, Percent_Identity=24.6612466124661, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21356223, Length=303, Percent_Identity=28.7128712871287, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI19923002, Length=367, Percent_Identity=25.6130790190736, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.10 [H]

Molecular weight: Translated: 40575; Mature: 40443

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRPPGGRGPRRRGAARTRNARAGRMRALVTGGAGFIGANLADRLASEGCEVVVFDALAR
CCCCCCCCCCCCCCCHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEEHHHHC
PGVERNLAWLKARHGRKITSVQADVRDARAVAEAARDVQVIFHLAAQVAVTTSLVQPMDD
CCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FEINVRGALNVLEAARRRRTPVIFASTNKVYGDLADVPLELAGEAYRPKDADLRARGVSE
CEEEHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCHHHCCCCCCCCCCCHHHCCCCC
ARPLDFHTPYGCSKGAADQYVLDYARSFDLPTCVLRMSCIYGPRQMGTEDQGWVAHFLIR
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHCCCCCCHHHHHHHHH
ALEGQPIVVYGDGRQVRDIMHVGDTVDAYMAAWRRIEEVAGRAFNLGGGPGNAVSLLQLL
HHCCCEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHH
GYIEEVIGRKVEVGFSDWRAGDQRYYVSDPSAAKQALQLADPRDWRAGVADLARWLAAER
HHHHHHHCCEEECCCHHHCCCCCEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
GPAGTARRPVEAA
CCCCCCCCCCCCC
>Mature Secondary Structure 
GRPPGGRGPRRRGAARTRNARAGRMRALVTGGAGFIGANLADRLASEGCEVVVFDALAR
CCCCCCCCCCCCCCHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEEHHHHC
PGVERNLAWLKARHGRKITSVQADVRDARAVAEAARDVQVIFHLAAQVAVTTSLVQPMDD
CCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FEINVRGALNVLEAARRRRTPVIFASTNKVYGDLADVPLELAGEAYRPKDADLRARGVSE
CEEEHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCHHHCCCCCCCCCCCHHHCCCCC
ARPLDFHTPYGCSKGAADQYVLDYARSFDLPTCVLRMSCIYGPRQMGTEDQGWVAHFLIR
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHCCCCCCHHHHHHHHH
ALEGQPIVVYGDGRQVRDIMHVGDTVDAYMAAWRRIEEVAGRAFNLGGGPGNAVSLLQLL
HHCCCEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHH
GYIEEVIGRKVEVGFSDWRAGDQRYYVSDPSAAKQALQLADPRDWRAGVADLARWLAAER
HHHHHHHCCEEECCCHHHCCCCCEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
GPAGTARRPVEAA
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2793833; 11677608; 12644504; 12642575 [H]