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The map label for this gene is rfbB [C]

Identifier: 197105546

GI number: 197105546

Start: 2335276

End: 2336286

Strand: Reverse

Name: rfbB [C]

Synonym: PHZ_c2083

Alternate gene names: 197105546

Gene position: 2336286-2335276 (Counterclockwise)

Preceding gene: 197105547

Following gene: 197105545

Centisome position: 58.46

GC content: 70.72

Gene sequence:

>1011_bases
ATGAAGAACGGACACGGCAAGAACATCCTCGTCGCCGGCGGCGCGGGCTTCCTGGGCTCCCACCTGTGCGAGCGCCTGGC
GGCCGAGGGCGCCCATGTCGTCTGCCTCGACAACTTCCAGACCGGCCGGCGAGAGAACCTGCAGCGGCTGGAGGGGCGCG
ACGGCTTCCAGGTGGTCGAGGCCGACATCGTCGACGCCCTGCCGTCGCGCCTGGCCAAGATGCGCTTCGACCGCGTCTAC
AACCTGGCCTGCGCCGCCTCGCCGCCGCTGTACCAGGCCGACCCCGAACACACCCTGATGACCAGCGTCATCGGGACCCG
GCAGCTGCTGAAGCTGGCCGAGGCCTCCGGCGCGCGGTTCCTGCAGGCCTCCACCAGCGAGATCTACGGCGATCCGGCGA
GCCATCCCCAGCCCGAGAGCTATTGGGGCAACGTCAACTGCACCGGCCCCCGGGCCTGCTACGACGAGGGCAAGCGGGCC
GCCGAGACGCTCTGCTTCGACTACGACCGGCTGGGCAAGGCCGAGGTACGGGTCGTGCGGATCTTCAACACCTACGGCCC
CCGTCTCGACGCCAGCGACGGGCGGGTGGTGTCGAACGTGGTCAGCCAGGCCCTGGCGGGCGAGGACATCACCGTCTTCG
GCGACGGCTCGCAGACCCGCTCCTTCTGCTACGTGGACGACCAGATCGACGGCCTCGTCCGGCTGATGGAATACGACGGC
GCCCAGCCGGGGCCGGTGAACATCGGCAATCCCGCCGAGCGGACGATCCTGGAGCTGGTGGACCTGGTGCTCGCCATGAC
CGGCTCGACGTCCGAGGTGGTCCACCGGCCGCTGCCGGTGGACGATCCCAGGCGCCGGCGGCCCGACATCTCCAAGGCCG
AGCGGCTGCTGGGCTGGACTCCGAAGACGCCGCTGGAGCAGGGGCTTCGCGCCACCATCGCCTGGTTCGAGGCCCGCGAG
GGCCGCGACCGGAAAGGCAAGCGGGCGGACGTCGTGCGGCTCTCGGCCTGA

Upstream 100 bases:

>100_bases
TCCACCGGGCGGCCGAGCTGGAGGCGCATCTGTCGGCGGCCGGGGCTCGCAACTCTCCTGAACTTCTGCTGGCAGGCGAC
GGGCGCTGAAGGGTTTTTCC

Downstream 100 bases:

>100_bases
GGGCGGAACGGCGCCCGCTCACGGGAATTCCTCGGCCATGTCCCGGCCCGCGAACGAGAAGCTGACCTACCCGCCGCCCG
CCGCGGAGGACATGGGCCTC

Product: dTDP-glucose 4,6-dehydratase protein

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKNGHGKNILVAGGAGFLGSHLCERLAAEGAHVVCLDNFQTGRRENLQRLEGRDGFQVVEADIVDALPSRLAKMRFDRVY
NLACAASPPLYQADPEHTLMTSVIGTRQLLKLAEASGARFLQASTSEIYGDPASHPQPESYWGNVNCTGPRACYDEGKRA
AETLCFDYDRLGKAEVRVVRIFNTYGPRLDASDGRVVSNVVSQALAGEDITVFGDGSQTRSFCYVDDQIDGLVRLMEYDG
AQPGPVNIGNPAERTILELVDLVLAMTGSTSEVVHRPLPVDDPRRRRPDISKAERLLGWTPKTPLEQGLRATIAWFEARE
GRDRKGKRADVVRLSA

Sequences:

>Translated_336_residues
MKNGHGKNILVAGGAGFLGSHLCERLAAEGAHVVCLDNFQTGRRENLQRLEGRDGFQVVEADIVDALPSRLAKMRFDRVY
NLACAASPPLYQADPEHTLMTSVIGTRQLLKLAEASGARFLQASTSEIYGDPASHPQPESYWGNVNCTGPRACYDEGKRA
AETLCFDYDRLGKAEVRVVRIFNTYGPRLDASDGRVVSNVVSQALAGEDITVFGDGSQTRSFCYVDDQIDGLVRLMEYDG
AQPGPVNIGNPAERTILELVDLVLAMTGSTSEVVHRPLPVDDPRRRRPDISKAERLLGWTPKTPLEQGLRATIAWFEARE
GRDRKGKRADVVRLSA
>Mature_336_residues
MKNGHGKNILVAGGAGFLGSHLCERLAAEGAHVVCLDNFQTGRRENLQRLEGRDGFQVVEADIVDALPSRLAKMRFDRVY
NLACAASPPLYQADPEHTLMTSVIGTRQLLKLAEASGARFLQASTSEIYGDPASHPQPESYWGNVNCTGPRACYDEGKRA
AETLCFDYDRLGKAEVRVVRIFNTYGPRLDASDGRVVSNVVSQALAGEDITVFGDGSQTRSFCYVDDQIDGLVRLMEYDG
AQPGPVNIGNPAERTILELVDLVLAMTGSTSEVVHRPLPVDDPRRRRPDISKAERLLGWTPKTPLEQGLRATIAWFEARE
GRDRKGKRADVVRLSA

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=310, Percent_Identity=51.9354838709677, Blast_Score=337, Evalue=9e-93,
Organism=Homo sapiens, GI7657641, Length=336, Percent_Identity=28.2738095238095, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI56237023, Length=347, Percent_Identity=27.3775216138329, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI56118217, Length=347, Percent_Identity=27.3775216138329, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI189083684, Length=347, Percent_Identity=27.3775216138329, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788353, Length=341, Percent_Identity=27.5659824046921, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI48994969, Length=344, Percent_Identity=27.906976744186, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788589, Length=338, Percent_Identity=26.3313609467456, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1786974, Length=334, Percent_Identity=26.9461077844311, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788365, Length=336, Percent_Identity=25, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17539532, Length=321, Percent_Identity=46.7289719626168, Blast_Score=316, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI17568069, Length=329, Percent_Identity=27.0516717325228, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI115532424, Length=326, Percent_Identity=26.6871165644172, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=335, Percent_Identity=27.4626865671642, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71982038, Length=337, Percent_Identity=27.299703264095, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319493, Length=365, Percent_Identity=24.9315068493151, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356223, Length=310, Percent_Identity=50.6451612903226, Blast_Score=333, Evalue=1e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36854; Mature: 36854

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNGHGKNILVAGGAGFLGSHLCERLAAEGAHVVCLDNFQTGRRENLQRLEGRDGFQVVE
CCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCCCEEHH
ADIVDALPSRLAKMRFDRVYNLACAASPPLYQADPEHTLMTSVIGTRQLLKLAEASGARF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEE
LQASTSEIYGDPASHPQPESYWGNVNCTGPRACYDEGKRAAETLCFDYDRLGKAEVRVVR
EECCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHCCCCCEEEEE
IFNTYGPRLDASDGRVVSNVVSQALAGEDITVFGDGSQTRSFCYVDDQIDGLVRLMEYDG
EEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECHHHHHHHHHHHHCC
AQPGPVNIGNPAERTILELVDLVLAMTGSTSEVVHRPLPVDDPRRRRPDISKAERLLGWT
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHCCCCHHHHHHHHCCC
PKTPLEQGLRATIAWFEAREGRDRKGKRADVVRLSA
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MKNGHGKNILVAGGAGFLGSHLCERLAAEGAHVVCLDNFQTGRRENLQRLEGRDGFQVVE
CCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCCCEEHH
ADIVDALPSRLAKMRFDRVYNLACAASPPLYQADPEHTLMTSVIGTRQLLKLAEASGARF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEE
LQASTSEIYGDPASHPQPESYWGNVNCTGPRACYDEGKRAAETLCFDYDRLGKAEVRVVR
EECCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHCCCCCEEEEE
IFNTYGPRLDASDGRVVSNVVSQALAGEDITVFGDGSQTRSFCYVDDQIDGLVRLMEYDG
EEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECHHHHHHHHHHHHCC
AQPGPVNIGNPAERTILELVDLVLAMTGSTSEVVHRPLPVDDPRRRRPDISKAERLLGWT
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHCCCCHHHHHHHHCCC
PKTPLEQGLRATIAWFEAREGRDRKGKRADVVRLSA
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]