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The map label for this gene is yclF [H]

Identifier: 197105476

GI number: 197105476

Start: 2253184

End: 2254527

Strand: Reverse

Name: yclF [H]

Synonym: PHZ_c2013

Alternate gene names: 197105476

Gene position: 2254527-2253184 (Counterclockwise)

Preceding gene: 197105477

Following gene: 197105475

Centisome position: 56.42

GC content: 72.25

Gene sequence:

>1344_bases
GTGGGGGAGCGCTCCGTGACGAGTTCGGGCGCGCCGCCGGCCAGGGCGTGGTTCGGCCAGCCGCCGGGCCTGACGATCCT
CTTCCTCACCGAGATGTGGGAGAAGTTCTCGTTCTACGGAATGCGGGCGCTGCTGGTCTACTACATGACCAAGCAGCTGC
TGATGCCCCAGGCCCAGGCCTCGATGGTCTACGGGCTCTACACGGCGTTCGTCTACTTCACGCCCATCCTGGGCGGGGTG
ATCGCCGACCGGTGGCTCGGCCGGCGCAAGGCCGTGATCCTCGGCGGCTCGATCATGGCGCTCGGCCACTTCCTGATGGC
CTTCGAACCGGCGTTCTATCCGGCGCTCGCCTGCATCGCCCTCGGCAACGGCTTCTTCCTGCCCAGCCTGCCCAGCCAGA
TCGGCGGGCTCTACGCGCCCGACGATCCGCGGCGGGTGCGGGCCTACAATGTCTACTACGTGGGCGTGAACCTGGGCGGG
TTCCTGGCCCCGCTGGTCTGCGGCACGCTGGGCGAGCTCTACGGCTGGCACTACGGCTTCGCCGCGGCCGGGATCGGCAT
GGTCGCGGGGCTGACGATCTACATCCTCGGCGGACGCCACCTGCCTGCCGAGGAGCCGCGACCCGCGTGCAGGGGCGATG
GTCCGCGGCGGCGCGGCGACCTGCGGCTGTTCCTGCTGCTGCTCGGCGTTGGGCTGGCGGTCGTGGTCTTCCGCGGCGCC
TACGAGCAGACCGGCAACACCCTGGCGCTCTGGGCCGACCAGGGCGTCGACCGCGGGGTGGGGGAGGGCTTCGTCATCCC
CATGACCTGGTTCCAGTCGCTGAACCCGCTGCTGGTGTTCGTCCTCACGCCGCTGTTCCTCGCGCACTGGGCCAGGCTGG
AGCGCTGGGGCCGCGAGCCGTCGCCGCTGGTGAAGATGTCCATCGGCTCGGGGGGCGTGGCGGCGGCGTTCCTGATGCTG
GCCGTCGTGGCGGGGACCTCGGGGCCGAGCGCGAGCTGGCTGTGGCTCGCGGCCTTCTTCGTCGTCCTCACCGCGGGCGA
GCTCTACATCCTGCCGGTCGGCCTCGGCCTCTTCGCCCGCCTGGCGCCGGCGGGGATGGCGGCGACGGCGGTGGCGGGCT
GGTTCCTCGCCGCCTTCGCCGGGAACCTGCTGGCGGGCGCCCTCGGCGCGTTCTGGAGCCGGCTGGATCCGGCGGTCTTC
TTCGCCGGCATGGGCGGCGTGGCTGCGATCGCCGCCGCGGTGCTGCTGGCGCTGGCCCCCTGGGCCCGGGGCGCGGAGGA
CGCCGGTGCGCCGCCCGCGGACGAGGATCTCAAGTCTGGACTGGAGCGCACGTTCCGTCGCTGA

Upstream 100 bases:

>100_bases
TCTGCGAGGTGGTGGACCTCGACGGGCCGATCTTCATCACCCGCGACCGCCTGCCGTCGGTCAGCTACGCGGACGGCCTG
ATCGCCTATCCGGAGCACGG

Downstream 100 bases:

>100_bases
CGGGCCGATTCAGCCTCATCAGGCTTTCGTCTGGTTGACAATTCTCTAATCAGGACCATCCTCGCCGAACAAGGATCATT
TTTCCGGGGGCGGACCAAAG

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MGERSVTSSGAPPARAWFGQPPGLTILFLTEMWEKFSFYGMRALLVYYMTKQLLMPQAQASMVYGLYTAFVYFTPILGGV
IADRWLGRRKAVILGGSIMALGHFLMAFEPAFYPALACIALGNGFFLPSLPSQIGGLYAPDDPRRVRAYNVYYVGVNLGG
FLAPLVCGTLGELYGWHYGFAAAGIGMVAGLTIYILGGRHLPAEEPRPACRGDGPRRRGDLRLFLLLLGVGLAVVVFRGA
YEQTGNTLALWADQGVDRGVGEGFVIPMTWFQSLNPLLVFVLTPLFLAHWARLERWGREPSPLVKMSIGSGGVAAAFLML
AVVAGTSGPSASWLWLAAFFVVLTAGELYILPVGLGLFARLAPAGMAATAVAGWFLAAFAGNLLAGALGAFWSRLDPAVF
FAGMGGVAAIAAAVLLALAPWARGAEDAGAPPADEDLKSGLERTFRR

Sequences:

>Translated_447_residues
MGERSVTSSGAPPARAWFGQPPGLTILFLTEMWEKFSFYGMRALLVYYMTKQLLMPQAQASMVYGLYTAFVYFTPILGGV
IADRWLGRRKAVILGGSIMALGHFLMAFEPAFYPALACIALGNGFFLPSLPSQIGGLYAPDDPRRVRAYNVYYVGVNLGG
FLAPLVCGTLGELYGWHYGFAAAGIGMVAGLTIYILGGRHLPAEEPRPACRGDGPRRRGDLRLFLLLLGVGLAVVVFRGA
YEQTGNTLALWADQGVDRGVGEGFVIPMTWFQSLNPLLVFVLTPLFLAHWARLERWGREPSPLVKMSIGSGGVAAAFLML
AVVAGTSGPSASWLWLAAFFVVLTAGELYILPVGLGLFARLAPAGMAATAVAGWFLAAFAGNLLAGALGAFWSRLDPAVF
FAGMGGVAAIAAAVLLALAPWARGAEDAGAPPADEDLKSGLERTFRR
>Mature_446_residues
GERSVTSSGAPPARAWFGQPPGLTILFLTEMWEKFSFYGMRALLVYYMTKQLLMPQAQASMVYGLYTAFVYFTPILGGVI
ADRWLGRRKAVILGGSIMALGHFLMAFEPAFYPALACIALGNGFFLPSLPSQIGGLYAPDDPRRVRAYNVYYVGVNLGGF
LAPLVCGTLGELYGWHYGFAAAGIGMVAGLTIYILGGRHLPAEEPRPACRGDGPRRRGDLRLFLLLLGVGLAVVVFRGAY
EQTGNTLALWADQGVDRGVGEGFVIPMTWFQSLNPLLVFVLTPLFLAHWARLERWGREPSPLVKMSIGSGGVAAAFLMLA
VVAGTSGPSASWLWLAAFFVVLTAGELYILPVGLGLFARLAPAGMAATAVAGWFLAAFAGNLLAGALGAFWSRLDPAVFF
AGMGGVAAIAAAVLLALAPWARGAEDAGAPPADEDLKSGLERTFRR

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI226371746, Length=346, Percent_Identity=26.3005780346821, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI4827008, Length=379, Percent_Identity=22.6912928759894, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI226371748, Length=334, Percent_Identity=26.6467065868263, Blast_Score=92, Evalue=9e-19,
Organism=Escherichia coli, GI1786927, Length=431, Percent_Identity=30.1624129930394, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI1790572, Length=192, Percent_Identity=41.6666666666667, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1787922, Length=472, Percent_Identity=25.4237288135593, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1789911, Length=474, Percent_Identity=24.6835443037975, Blast_Score=139, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71987453, Length=350, Percent_Identity=23.7142857142857, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17569141, Length=392, Percent_Identity=20.9183673469388, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28571098, Length=357, Percent_Identity=24.9299719887955, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28571102, Length=357, Percent_Identity=24.9299719887955, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28571100, Length=357, Percent_Identity=24.9299719887955, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24639581, Length=344, Percent_Identity=22.9651162790698, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639585, Length=326, Percent_Identity=23.3128834355828, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639583, Length=325, Percent_Identity=23.3846153846154, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 47640; Mature: 47509

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS50850 MFS ; PS01022 PTR2_1 ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGERSVTSSGAPPARAWFGQPPGLTILFLTEMWEKFSFYGMRALLVYYMTKQLLMPQAQA
CCCCCCCCCCCCCCHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
SMVYGLYTAFVYFTPILGGVIADRWLGRRKAVILGGSIMALGHFLMAFEPAFYPALACIA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCHHHHHHHHHHH
LGNGFFLPSLPSQIGGLYAPDDPRRVRAYNVYYVGVNLGGFLAPLVCGTLGELYGWHYGF
HCCCCCCCCCHHHHCCCCCCCCCCEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
AAAGIGMVAGLTIYILGGRHLPAEEPRPACRGDGPRRRGDLRLFLLLLGVGLAVVVFRGA
HHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
YEQTGNTLALWADQGVDRGVGEGFVIPMTWFQSLNPLLVFVLTPLFLAHWARLERWGREP
HHHCCCEEEEEECCCCCCCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
SPLVKMSIGSGGVAAAFLMLAVVAGTSGPSASWLWLAAFFVVLTAGELYILPVGLGLFAR
CCEEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHH
LAPAGMAATAVAGWFLAAFAGNLLAGALGAFWSRLDPAVFFAGMGGVAAIAAAVLLALAP
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHCC
WARGAEDAGAPPADEDLKSGLERTFRR
CCCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
GERSVTSSGAPPARAWFGQPPGLTILFLTEMWEKFSFYGMRALLVYYMTKQLLMPQAQA
CCCCCCCCCCCCCHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
SMVYGLYTAFVYFTPILGGVIADRWLGRRKAVILGGSIMALGHFLMAFEPAFYPALACIA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCHHHHHHHHHHH
LGNGFFLPSLPSQIGGLYAPDDPRRVRAYNVYYVGVNLGGFLAPLVCGTLGELYGWHYGF
HCCCCCCCCCHHHHCCCCCCCCCCEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
AAAGIGMVAGLTIYILGGRHLPAEEPRPACRGDGPRRRGDLRLFLLLLGVGLAVVVFRGA
HHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
YEQTGNTLALWADQGVDRGVGEGFVIPMTWFQSLNPLLVFVLTPLFLAHWARLERWGREP
HHHCCCEEEEEECCCCCCCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
SPLVKMSIGSGGVAAAFLMLAVVAGTSGPSASWLWLAAFFVVLTAGELYILPVGLGLFAR
CCEEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHH
LAPAGMAATAVAGWFLAAFAGNLLAGALGAFWSRLDPAVFFAGMGGVAAIAAAVLLALAP
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHCC
WARGAEDAGAPPADEDLKSGLERTFRR
CCCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]