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The map label for this gene is cirA [H]

Identifier: 197105465

GI number: 197105465

Start: 2237017

End: 2239401

Strand: Reverse

Name: cirA [H]

Synonym: PHZ_c2002

Alternate gene names: 197105465

Gene position: 2239401-2237017 (Counterclockwise)

Preceding gene: 197105466

Following gene: 197105464

Centisome position: 56.04

GC content: 68.51

Gene sequence:

>2385_bases
ATGACGATGACGAATTCACGACGTGTTCGGTTGCTGAGCGGCGCCGCCGCTGCGCTGCTCGGCGGATTCGCCGGAACCGC
CGCCGCGGCCCAGGCGGAAGGGGGCTCCATCGACGTGTCGGAGGTGGTCGTGACCGCCACCAAGCAGGCCGTCCGTCTCG
ACAAGGTGCCGCTGTCGGTCAGCGCCTACACGCCCGAGGCGATCGAGAAGCGCGGCATCCGCGACATCCGGGACGTGGCG
CTCCAGACGCCGGGGGTGGACATCCCGAACGACGGCGGCGGGCGCAGCGTCCAGCGCGTGTCGATCCGGGGCATCGAGTC
CACCGCCGGCGCCGCGACAGCCGCGGTCTACATCGACGACACTCCGATCCAGGCTCGCAACGCCTCGATCAACTATTCCG
GCTCGACCATTCCCTACATCTTCGATCTTGAGCGGATCGAGGTGCTGCGCGGCCCGCAGGGAACCCTGTTCGGCGCCAGC
TCGCAGGGCGGCGCGATCCGCTTCATCACCCCGACGCCGAGCGTCACCCGCTACACCGCCATGGCGCGGGCCCGCGCCAG
CGTCGTCGAGGACGGCGACGCCAGCTACGAGCTGGGCGTGGCCGCCGGCGGCCCGATCGTCGAGGACCGCCTGGGCTTCC
GCGCCAGCTTCCTCTACCGCGACGAGGGCGGGTGGATCGATCGCCAGGACTGGCAGGATCCGACCGAGCGGCACAGCAAC
GTGAACTCGACCGAGTCCACGGTCTTCCGGGCGGCCCTGAACTTCAAGCCGGTCGACTGGATGTCGATCCAGCCGAGCCT
GTTCTACCAGAACGTCAAGCAGAACGACCGCTCGCCGCTCTACTCGGCCTGCCCCGACAGCCTGCCCCTGGCGCCCGGCT
TCGATCCGTGCCCGCGCGGCGTGGCGGACCCGGACGACGGCAAGTTCCTCAGCTACTCGACGATCGCCCAGCCGGGCAGC
GACAAGTTCTACCTCCCGTCGCTGAAGATGGTGGCAGACAAGGGACCGGTGACCTTCACCTCGGTCACTTCGTACCTCTA
CCGCCACGTGATCCAGCTGAACGACGCGACCTACAACAACGACCGCGTGTCCCTGGGCAACAACTGGCTCTTCCCGGTCA
TCCCGGGCCGCGAACTGCAGACCTACCAGAACCCCGACACCGAACAGCGCCTGTTCACCCAGGAGCTCCGCCTCGCCAGC
GCCGACCCGTCGGCCCGGGTGCGGTGGACCGCGGGCGTCTACTACTCGCGCAGCTCGCTGAAGTCGGACCTTCCGATCAC
GTCGGCGCACTATCCGGATGCGTACGCCATCCGCTTCGGCCGGCCGCTCGCCGCCACGCCGTTCATGGTCGACGGGATCC
ACCGCTACTACGGCAACGAGAACACGATCGAGAAGACGCTGGCCGCCTTCGGCAACGTGGACGTCACCCTCCTGGAGGGG
CTGACGCTCAGCGTCGGCGCGCGCTACTCGCGTGACACCATCGACTTCGACATCGTCGAGCGGGGCGTCTCCTACGCGGG
CGGCATCTCCACGGCGGCCGGCACGCTCAAGGAGAAGCCGTTCACCCCGCGCGTGGCGCTGTCTTGGCAGCAGTCCGAGG
ACACCCTCGTCTACGGCTCCTACGCTCGCGGCTACCGTGCGGGCGGCGTGAACAAGGCGGTGCCGGACATCTGCGAGGCC
GATCTGGCGACCCTGGGGATCGACGGCGGCAACACCTACGACTCCGACAAGACCGACACCTACGAACTCGGCGTGAAGAG
CGCCCTGTTCGAGCGCCGCGTCACGTTCCAGGCCAGTGTGTTCCGGACCAAGTGGAAGGACATTCAGCAGCAGATCCGCC
TGCCCTGCGCCTTCAGCCTCGTGGCCAACACCGCCAGCGCGGTCAGCCAGGGCGGCGACCTGAGCGTCAGCTTCCGGGCG
ACCGACAACCTCACGCTCACAGCGGCCGTGGGCTACACCGACGCCGAGTACGAGAAGACGATCATCGTCGGCACCTCGCC
GCTGGTGTTCGAGGGCCAGTCGCTGGGCGCCACGCCCTGGACCGTGAACCTGGCCGCCGATTACAGCTTCATGGCCTTCG
GCCGGGACGCCTTCGCCCGGGCGCAGTACACGTCGAAGTCGGCGGAGGACGGTCCGTACCCCTACCAGAACCCGATGAGT
TCGCTGTACGACCCGACGCGGGGCGGCGGCTATGGCACGAGCCAGCTCGACCTGCGGGTCGGCGTCGACGTGACGCCGCT
GGTGACCGTGGAGGCCTATGTGGAGAACGCGCTGAACGAGGTGTCCTACCTCAGCAACGCGCCGACCTACATCCGCGGAC
CGCTGTGGCTGGCGACCGCCGCCAAGCCGAGGGTCATCGGCATCCAGGCGACCGCCCGCTACTAG

Upstream 100 bases:

>100_bases
CGCGGAAACTCCCCATGAGGCCCTGCGGGGGGTCTTCGCCATAACAGGATCCAACGGCCGCGGCCGTGCGAGGTCCGACG
TCGCCAAAGGGGTCTGACAG

Downstream 100 bases:

>100_bases
TCGCGACCCGTTCGAGGAGAGCTACGATGAACGCCCGCCTGCGTCTGCTCGTCACCGGCCTCGCCAGCGTCTGCGCCATC
GGCGCTACGCCGGCGCTGGC

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 794; Mature: 793

Protein sequence:

>794_residues
MTMTNSRRVRLLSGAAAALLGGFAGTAAAAQAEGGSIDVSEVVVTATKQAVRLDKVPLSVSAYTPEAIEKRGIRDIRDVA
LQTPGVDIPNDGGGRSVQRVSIRGIESTAGAATAAVYIDDTPIQARNASINYSGSTIPYIFDLERIEVLRGPQGTLFGAS
SQGGAIRFITPTPSVTRYTAMARARASVVEDGDASYELGVAAGGPIVEDRLGFRASFLYRDEGGWIDRQDWQDPTERHSN
VNSTESTVFRAALNFKPVDWMSIQPSLFYQNVKQNDRSPLYSACPDSLPLAPGFDPCPRGVADPDDGKFLSYSTIAQPGS
DKFYLPSLKMVADKGPVTFTSVTSYLYRHVIQLNDATYNNDRVSLGNNWLFPVIPGRELQTYQNPDTEQRLFTQELRLAS
ADPSARVRWTAGVYYSRSSLKSDLPITSAHYPDAYAIRFGRPLAATPFMVDGIHRYYGNENTIEKTLAAFGNVDVTLLEG
LTLSVGARYSRDTIDFDIVERGVSYAGGISTAAGTLKEKPFTPRVALSWQQSEDTLVYGSYARGYRAGGVNKAVPDICEA
DLATLGIDGGNTYDSDKTDTYELGVKSALFERRVTFQASVFRTKWKDIQQQIRLPCAFSLVANTASAVSQGGDLSVSFRA
TDNLTLTAAVGYTDAEYEKTIIVGTSPLVFEGQSLGATPWTVNLAADYSFMAFGRDAFARAQYTSKSAEDGPYPYQNPMS
SLYDPTRGGGYGTSQLDLRVGVDVTPLVTVEAYVENALNEVSYLSNAPTYIRGPLWLATAAKPRVIGIQATARY

Sequences:

>Translated_794_residues
MTMTNSRRVRLLSGAAAALLGGFAGTAAAAQAEGGSIDVSEVVVTATKQAVRLDKVPLSVSAYTPEAIEKRGIRDIRDVA
LQTPGVDIPNDGGGRSVQRVSIRGIESTAGAATAAVYIDDTPIQARNASINYSGSTIPYIFDLERIEVLRGPQGTLFGAS
SQGGAIRFITPTPSVTRYTAMARARASVVEDGDASYELGVAAGGPIVEDRLGFRASFLYRDEGGWIDRQDWQDPTERHSN
VNSTESTVFRAALNFKPVDWMSIQPSLFYQNVKQNDRSPLYSACPDSLPLAPGFDPCPRGVADPDDGKFLSYSTIAQPGS
DKFYLPSLKMVADKGPVTFTSVTSYLYRHVIQLNDATYNNDRVSLGNNWLFPVIPGRELQTYQNPDTEQRLFTQELRLAS
ADPSARVRWTAGVYYSRSSLKSDLPITSAHYPDAYAIRFGRPLAATPFMVDGIHRYYGNENTIEKTLAAFGNVDVTLLEG
LTLSVGARYSRDTIDFDIVERGVSYAGGISTAAGTLKEKPFTPRVALSWQQSEDTLVYGSYARGYRAGGVNKAVPDICEA
DLATLGIDGGNTYDSDKTDTYELGVKSALFERRVTFQASVFRTKWKDIQQQIRLPCAFSLVANTASAVSQGGDLSVSFRA
TDNLTLTAAVGYTDAEYEKTIIVGTSPLVFEGQSLGATPWTVNLAADYSFMAFGRDAFARAQYTSKSAEDGPYPYQNPMS
SLYDPTRGGGYGTSQLDLRVGVDVTPLVTVEAYVENALNEVSYLSNAPTYIRGPLWLATAAKPRVIGIQATARY
>Mature_793_residues
TMTNSRRVRLLSGAAAALLGGFAGTAAAAQAEGGSIDVSEVVVTATKQAVRLDKVPLSVSAYTPEAIEKRGIRDIRDVAL
QTPGVDIPNDGGGRSVQRVSIRGIESTAGAATAAVYIDDTPIQARNASINYSGSTIPYIFDLERIEVLRGPQGTLFGASS
QGGAIRFITPTPSVTRYTAMARARASVVEDGDASYELGVAAGGPIVEDRLGFRASFLYRDEGGWIDRQDWQDPTERHSNV
NSTESTVFRAALNFKPVDWMSIQPSLFYQNVKQNDRSPLYSACPDSLPLAPGFDPCPRGVADPDDGKFLSYSTIAQPGSD
KFYLPSLKMVADKGPVTFTSVTSYLYRHVIQLNDATYNNDRVSLGNNWLFPVIPGRELQTYQNPDTEQRLFTQELRLASA
DPSARVRWTAGVYYSRSSLKSDLPITSAHYPDAYAIRFGRPLAATPFMVDGIHRYYGNENTIEKTLAAFGNVDVTLLEGL
TLSVGARYSRDTIDFDIVERGVSYAGGISTAAGTLKEKPFTPRVALSWQQSEDTLVYGSYARGYRAGGVNKAVPDICEAD
LATLGIDGGNTYDSDKTDTYELGVKSALFERRVTFQASVFRTKWKDIQQQIRLPCAFSLVANTASAVSQGGDLSVSFRAT
DNLTLTAAVGYTDAEYEKTIIVGTSPLVFEGQSLGATPWTVNLAADYSFMAFGRDAFARAQYTSKSAEDGPYPYQNPMSS
LYDPTRGGGYGTSQLDLRVGVDVTPLVTVEAYVENALNEVSYLSNAPTYIRGPLWLATAAKPRVIGIQATARY

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=182, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 86012; Mature: 85881

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMTNSRRVRLLSGAAAALLGGFAGTAAAAQAEGGSIDVSEVVVTATKQAVRLDKVPLSV
CCCCCCCEEEEEHHHHHHHHHHHCCCHHHHCCCCCCEEHHHHHHHHHHHHHEEECCCEEE
SAYTPEAIEKRGIRDIRDVALQTPGVDIPNDGGGRSVQRVSIRGIESTAGAATAAVYIDD
ECCCHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEC
TPIQARNASINYSGSTIPYIFDLERIEVLRGPQGTLFGASSQGGAIRFITPTPSVTRYTA
CCCCCCCCEEEECCCCCCEEEEHHHHHHHCCCCCCEEECCCCCCEEEEECCCCCHHHHHH
MARARASVVEDGDASYELGVAAGGPIVEDRLGFRASFLYRDEGGWIDRQDWQDPTERHSN
HHHHHHHHCCCCCCCEEEEEECCCCCHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHCC
VNSTESTVFRAALNFKPVDWMSIQPSLFYQNVKQNDRSPLYSACPDSLPLAPGFDPCPRG
CCCHHHHHEEEECCCCCCCCEECCHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCCC
VADPDDGKFLSYSTIAQPGSDKFYLPSLKMVADKGPVTFTSVTSYLYRHVIQLNDATYNN
CCCCCCCCEEEEEECCCCCCCCEECCCCCEEECCCCEEHHHHHHHHHHHHEEECCCCCCC
DRVSLGNNWLFPVIPGRELQTYQNPDTEQRLFTQELRLASADPSARVRWTAGVYYSRSSL
CEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEHHHC
KSDLPITSAHYPDAYAIRFGRPLAATPFMVDGIHRYYGNENTIEKTLAAFGNVDVTLLEG
CCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECC
LTLSVGARYSRDTIDFDIVERGVSYAGGISTAAGTLKEKPFTPRVALSWQQSEDTLVYGS
EEEECCCCCCCCCCCHHHHHHCCHHCCCCHHHHHHHCCCCCCCEEEEEEECCCCEEEEEC
YARGYRAGGVNKAVPDICEADLATLGIDGGNTYDSDKTDTYELGVKSALFERRVTFQASV
CCCCEECCCCCCCCHHHHHCCHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
FRTKWKDIQQQIRLPCAFSLVANTASAVSQGGDLSVSFRATDNLTLTAAVGYTDAEYEKT
HHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEECCCCCCCCEE
IIVGTSPLVFEGQSLGATPWTVNLAADYSFMAFGRDAFARAQYTSKSAEDGPYPYQNPMS
EEEECCCEEEECCCCCCCCEEEEEECCCEEEEECCHHHHHHHHCCCCCCCCCCCCCCCHH
SLYDPTRGGGYGTSQLDLRVGVDVTPLVTVEAYVENALNEVSYLSNAPTYIRGPLWLATA
HHCCCCCCCCCCCCEEEEEECCCCCCEEEHHHHHHHHHHHHHHHCCCCCEEECCEEEEEC
AKPRVIGIQATARY
CCCEEEEEEEECCC
>Mature Secondary Structure 
TMTNSRRVRLLSGAAAALLGGFAGTAAAAQAEGGSIDVSEVVVTATKQAVRLDKVPLSV
CCCCCCEEEEEHHHHHHHHHHHCCCHHHHCCCCCCEEHHHHHHHHHHHHHEEECCCEEE
SAYTPEAIEKRGIRDIRDVALQTPGVDIPNDGGGRSVQRVSIRGIESTAGAATAAVYIDD
ECCCHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEC
TPIQARNASINYSGSTIPYIFDLERIEVLRGPQGTLFGASSQGGAIRFITPTPSVTRYTA
CCCCCCCCEEEECCCCCCEEEEHHHHHHHCCCCCCEEECCCCCCEEEEECCCCCHHHHHH
MARARASVVEDGDASYELGVAAGGPIVEDRLGFRASFLYRDEGGWIDRQDWQDPTERHSN
HHHHHHHHCCCCCCCEEEEEECCCCCHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHCC
VNSTESTVFRAALNFKPVDWMSIQPSLFYQNVKQNDRSPLYSACPDSLPLAPGFDPCPRG
CCCHHHHHEEEECCCCCCCCEECCHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCCC
VADPDDGKFLSYSTIAQPGSDKFYLPSLKMVADKGPVTFTSVTSYLYRHVIQLNDATYNN
CCCCCCCCEEEEEECCCCCCCCEECCCCCEEECCCCEEHHHHHHHHHHHHEEECCCCCCC
DRVSLGNNWLFPVIPGRELQTYQNPDTEQRLFTQELRLASADPSARVRWTAGVYYSRSSL
CEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEHHHC
KSDLPITSAHYPDAYAIRFGRPLAATPFMVDGIHRYYGNENTIEKTLAAFGNVDVTLLEG
CCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECC
LTLSVGARYSRDTIDFDIVERGVSYAGGISTAAGTLKEKPFTPRVALSWQQSEDTLVYGS
EEEECCCCCCCCCCCHHHHHHCCHHCCCCHHHHHHHCCCCCCCEEEEEEECCCCEEEEEC
YARGYRAGGVNKAVPDICEADLATLGIDGGNTYDSDKTDTYELGVKSALFERRVTFQASV
CCCCEECCCCCCCCHHHHHCCHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
FRTKWKDIQQQIRLPCAFSLVANTASAVSQGGDLSVSFRATDNLTLTAAVGYTDAEYEKT
HHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEECCCCCCCCEE
IIVGTSPLVFEGQSLGATPWTVNLAADYSFMAFGRDAFARAQYTSKSAEDGPYPYQNPMS
EEEECCCEEEECCCCCCCCEEEEEECCCEEEEECCHHHHHHHHCCCCCCCCCCCCCCCHH
SLYDPTRGGGYGTSQLDLRVGVDVTPLVTVEAYVENALNEVSYLSNAPTYIRGPLWLATA
HHCCCCCCCCCCCCEEEEEECCCCCCEEEHHHHHHHHHHHHHHHCCCCCEEECCEEEEEC
AKPRVIGIQATARY
CCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]