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The map label for this gene is ompR [H]

Identifier: 197105366

GI number: 197105366

Start: 2129920

End: 2130669

Strand: Direct

Name: ompR [H]

Synonym: PHZ_c1903

Alternate gene names: 197105366

Gene position: 2129920-2130669 (Clockwise)

Preceding gene: 197105365

Following gene: 197105367

Centisome position: 53.3

GC content: 72.53

Gene sequence:

>750_bases
ATGCTGGGCGCCATGGAGCTTGCAGCTGACATGGCCGGCGCCGGGGCCCGCATCCTGATGGTCGACGACGACCCCGGCAT
CCGGGACGTGGTCTCCGACTTCCTGGGCCGCCACGGCTACAAGGTGGAGACCGCCGCCGACGCGCCCGAGATGGAGCGCG
TGCTGGAGCGCGGCCCGGTGGACCTGATCGTCCTCGACGTGATGCTGCCCGGCGAGGACGGCCTGGCGATCTGCCGCCGG
CTGACCACGGCCGACAACGCCCCGCCGATCATCATGCTGTCGGCCATGGGCGAGGACACCGACCGTATCGTCGGCCTGGA
GCTGGGCGCCGACGACTACCTGGCCAAGCCGTGCAACCCGCGCGAGCTGCTGGCGCGCGTCCGGGCCGTGCTGCGCCGGG
CCGAGCAGCGGACGAACGGCGGCGCGCTGGGCGCCGGCTGCGAGTTCGCCGGCTGGCGGCTGGACCTCGTGCGGCGCGAG
CTGCGCTCGCCGCAGGGCGTGGTGGTGAACCTGTCCTCGGGCGAGTTCAGCCTGCTGCGCGCCTTCGTCGAGCGGCCGCA
GCGCGTGCTGACCCGCGACCAGCTGCTGGAGTTCGCCCGCGGCCCCGACAGCGACGCATTCGACCGGGCCATCGACGTCC
AGATCAGCCGGCTGCGGCGCAAGCTGGACGACGGCGGCGGGGGCCACGACCTGATCCGCACCATCCGCAACGAAGGCTAC
ATGTTCACCGCCAAGGTGAAGCGGACATGA

Upstream 100 bases:

>100_bases
CCGCAGCAACCCCTTCGTCGCGGACGCGGTCCTGGCCGACGAGTAAGCGGCGTGACACGCGCGTTTCATCCGAGACATTC
GAGCGTTACGGCGCCCGCCC

Downstream 100 bases:

>100_bases
GTCCGGCGGGCCGGCCGACGGCCTCGTTCTTCGTCCAGCTCCTGACCCTGACCGGCCTGACGCTGGTGGCCGCCTGGGCG
ATCAGCATCCTGCTGCTGTT

Product: response regulator(with CheY-like receiver domain and winged-helix DNA-binding domain)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MLGAMELAADMAGAGARILMVDDDPGIRDVVSDFLGRHGYKVETAADAPEMERVLERGPVDLIVLDVMLPGEDGLAICRR
LTTADNAPPIIMLSAMGEDTDRIVGLELGADDYLAKPCNPRELLARVRAVLRRAEQRTNGGALGAGCEFAGWRLDLVRRE
LRSPQGVVVNLSSGEFSLLRAFVERPQRVLTRDQLLEFARGPDSDAFDRAIDVQISRLRRKLDDGGGGHDLIRTIRNEGY
MFTAKVKRT

Sequences:

>Translated_249_residues
MLGAMELAADMAGAGARILMVDDDPGIRDVVSDFLGRHGYKVETAADAPEMERVLERGPVDLIVLDVMLPGEDGLAICRR
LTTADNAPPIIMLSAMGEDTDRIVGLELGADDYLAKPCNPRELLARVRAVLRRAEQRTNGGALGAGCEFAGWRLDLVRRE
LRSPQGVVVNLSSGEFSLLRAFVERPQRVLTRDQLLEFARGPDSDAFDRAIDVQISRLRRKLDDGGGGHDLIRTIRNEGY
MFTAKVKRT
>Mature_249_residues
MLGAMELAADMAGAGARILMVDDDPGIRDVVSDFLGRHGYKVETAADAPEMERVLERGPVDLIVLDVMLPGEDGLAICRR
LTTADNAPPIIMLSAMGEDTDRIVGLELGADDYLAKPCNPRELLARVRAVLRRAEQRTNGGALGAGCEFAGWRLDLVRRE
LRSPQGVVVNLSSGEFSLLRAFVERPQRVLTRDQLLEFARGPDSDAFDRAIDVQISRLRRKLDDGGGGHDLIRTIRNEGY
MFTAKVKRT

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=47.5982532751092, Blast_Score=204, Evalue=6e-54,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=34.4827586206897, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=37.5, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1788394, Length=240, Percent_Identity=34.5833333333333, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=39.3939393939394, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=35.3448275862069, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=37.280701754386, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=33.9130434782609, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1787229, Length=237, Percent_Identity=34.5991561181435, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI87082012, Length=231, Percent_Identity=35.9307359307359, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=31.7180616740088, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=33.6244541484716, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=31.8777292576419, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1786911, Length=210, Percent_Identity=35.2380952380952, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27327; Mature: 27327

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGAMELAADMAGAGARILMVDDDPGIRDVVSDFLGRHGYKVETAADAPEMERVLERGPV
CCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHCCCC
DLIVLDVMLPGEDGLAICRRLTTADNAPPIIMLSAMGEDTDRIVGLELGADDYLAKPCNP
EEEEEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEECCCHHHCCCCCH
RELLARVRAVLRRAEQRTNGGALGAGCEFAGWRLDLVRRELRSPQGVVVNLSSGEFSLLR
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHH
AFVERPQRVLTRDQLLEFARGPDSDAFDRAIDVQISRLRRKLDDGGGGHDLIRTIRNEGY
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCE
MFTAKVKRT
EEEEEEECC
>Mature Secondary Structure
MLGAMELAADMAGAGARILMVDDDPGIRDVVSDFLGRHGYKVETAADAPEMERVLERGPV
CCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHCCCC
DLIVLDVMLPGEDGLAICRRLTTADNAPPIIMLSAMGEDTDRIVGLELGADDYLAKPCNP
EEEEEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEECCCHHHCCCCCH
RELLARVRAVLRRAEQRTNGGALGAGCEFAGWRLDLVRRELRSPQGVVVNLSSGEFSLLR
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHH
AFVERPQRVLTRDQLLEFARGPDSDAFDRAIDVQISRLRRKLDDGGGGHDLIRTIRNEGY
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCE
MFTAKVKRT
EEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]