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The map label for this gene is lepB [H]

Identifier: 197105334

GI number: 197105334

Start: 2098591

End: 2099367

Strand: Reverse

Name: lepB [H]

Synonym: PHZ_c1871

Alternate gene names: 197105334

Gene position: 2099367-2098591 (Counterclockwise)

Preceding gene: 197105337

Following gene: 197105333

Centisome position: 52.53

GC content: 67.31

Gene sequence:

>777_bases
ATGAGCGAGAACGTGCAGAGCGCGCACAGCCCCGAAAAATCCGGCGCGGCGAACGAGTTCGTCGAGATCGTCAAGACGGT
GGTCTACGCGCTGCTGATCGCGCTCGTTCTGCGCGTGGTGTTCTTCCAGCCCTTCACCATCCCCTCGGCCTCGATGGAGC
CGAACCTGTACGAGGGCGACTACATCATCGTCTCCAAGTGGTCCTACGGCTACTCGAAGCACTCCATCCCCTTCAGCCCG
CCGCTGTTCGAGGGGCGTATCTTCGGCGGCTCGCCCGAGCGCGGCGACGTGGTGGTCTTCAAACTGCCCAGCGACAACCG
CACCGACTACGTCAAGCGGGTGATCGGCCTGCCGGGCGACCGCGTCCAGATGAAGGACGGCCTGCTCTACGTGAACGGCG
CCCTGGTCGAGCGCCAGCCGCTGCCGCCGGCCCGCACCGACATGGGCGGCTTCGTCCGCGAGGTGGCCCAGTACCGCGAG
ACCGTGAACGGCGCCTCTTTCGCCACCCAGGACTTCGGGACCGACGGCGACCTCGACGACACCGAGCAGTTCGTGGTCCC
CGAGGGCCACTACTTCATGCTGGGCGACAACCGCGACAACTCGATGGACAGCCGCGTTCCGCCCGGCGCCGGCGGCGTCG
GCTTCGTCCCGGCCGAGAACCTGGTCGGCAAGGCCCAGATCGTCCTCCTGTCCTGGGAGCCCGAGGCCTCGGTCTTCAAG
CCCTGGACCTGGGTGCTCGACGCCCGGCCCAGCCGCTTCTTCAAGGTCCTGCACTAG

Upstream 100 bases:

>100_bases
TGCGTGAAGCAGAGTTCACGGGCGCGGCGCTTGCCCGTGGGCTATCCAGCGTCTACCCAACGCTTCGCTCCGGCCCGCCG
GGGCCCACCAGGGACGTTTC

Downstream 100 bases:

>100_bases
TCCATGAACGCCCGTGCGGCCGCCGTCGCCGAACTCGAGCGGCGCATCGGCTACGTCTTCACCGACCGCGACCTGCTGGA
ACGGGCGCTGACCCACGCCA

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSENVQSAHSPEKSGAANEFVEIVKTVVYALLIALVLRVVFFQPFTIPSASMEPNLYEGDYIIVSKWSYGYSKHSIPFSP
PLFEGRIFGGSPERGDVVVFKLPSDNRTDYVKRVIGLPGDRVQMKDGLLYVNGALVERQPLPPARTDMGGFVREVAQYRE
TVNGASFATQDFGTDGDLDDTEQFVVPEGHYFMLGDNRDNSMDSRVPPGAGGVGFVPAENLVGKAQIVLLSWEPEASVFK
PWTWVLDARPSRFFKVLH

Sequences:

>Translated_258_residues
MSENVQSAHSPEKSGAANEFVEIVKTVVYALLIALVLRVVFFQPFTIPSASMEPNLYEGDYIIVSKWSYGYSKHSIPFSP
PLFEGRIFGGSPERGDVVVFKLPSDNRTDYVKRVIGLPGDRVQMKDGLLYVNGALVERQPLPPARTDMGGFVREVAQYRE
TVNGASFATQDFGTDGDLDDTEQFVVPEGHYFMLGDNRDNSMDSRVPPGAGGVGFVPAENLVGKAQIVLLSWEPEASVFK
PWTWVLDARPSRFFKVLH
>Mature_257_residues
SENVQSAHSPEKSGAANEFVEIVKTVVYALLIALVLRVVFFQPFTIPSASMEPNLYEGDYIIVSKWSYGYSKHSIPFSPP
LFEGRIFGGSPERGDVVVFKLPSDNRTDYVKRVIGLPGDRVQMKDGLLYVNGALVERQPLPPARTDMGGFVREVAQYRET
VNGASFATQDFGTDGDLDDTEQFVVPEGHYFMLGDNRDNSMDSRVPPGAGGVGFVPAENLVGKAQIVLLSWEPEASVFKP
WTWVLDARPSRFFKVLH

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=104, Percent_Identity=42.3076923076923, Blast_Score=88, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 28596; Mature: 28464

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENVQSAHSPEKSGAANEFVEIVKTVVYALLIALVLRVVFFQPFTIPSASMEPNLYEGD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCC
YIIVSKWSYGYSKHSIPFSPPLFEGRIFGGSPERGDVVVFKLPSDNRTDYVKRVIGLPGD
EEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEECCCCCHHHHHHHHHCCCCC
RVQMKDGLLYVNGALVERQPLPPARTDMGGFVREVAQYRETVNGASFATQDFGTDGDLDD
EEEECCCEEEECCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCC
TEQFVVPEGHYFMLGDNRDNSMDSRVPPGAGGVGFVPAENLVGKAQIVLLSWEPEASVFK
CCEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCC
PWTWVLDARPSRFFKVLH
CEEEEEECCHHHHHHCCC
>Mature Secondary Structure 
SENVQSAHSPEKSGAANEFVEIVKTVVYALLIALVLRVVFFQPFTIPSASMEPNLYEGD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCC
YIIVSKWSYGYSKHSIPFSPPLFEGRIFGGSPERGDVVVFKLPSDNRTDYVKRVIGLPGD
EEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEECCCCCHHHHHHHHHCCCCC
RVQMKDGLLYVNGALVERQPLPPARTDMGGFVREVAQYRETVNGASFATQDFGTDGDLDD
EEEECCCEEEECCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCC
TEQFVVPEGHYFMLGDNRDNSMDSRVPPGAGGVGFVPAENLVGKAQIVLLSWEPEASVFK
CCEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCC
PWTWVLDARPSRFFKVLH
CEEEEEECCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA