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The map label for this gene is nuoH

Identifier: 197105260

GI number: 197105260

Start: 2011456

End: 2012550

Strand: Reverse

Name: nuoH

Synonym: PHZ_c1797

Alternate gene names: 197105260

Gene position: 2012550-2011456 (Counterclockwise)

Preceding gene: 197105261

Following gene: 197105259

Centisome position: 50.36

GC content: 65.21

Gene sequence:

>1095_bases
TTGATGGACCCGGCTGCCACCTCCTTCTGGGCCACCCCCGTCGGCTGGACCCTGGTCACCGCCGGCCAGATCCTGGCCGT
GATGATCTGGATCCTGCTGTCGCTGGCCTTCCTGCTGCTGGCCGACCGCAAGATCTGGGCGGGCGTGCAGATGCGCAAAG
GGCCCAACGTGGTGGGTCCGTTCGGCCTGCTGCAGTCCTTCGCCGACTTCCTGAAGTTCGTGCTGAAGGAGATCGTCATC
CCGTCGGGCGCTGACAAGACGGTCTTCCTGCTGGCCCCGCTGATCAGCTTCACCCTGGCGTTCGCCGCCTGGGCGGTGAT
CCCGCTGGCGCCCGGCTGGGTGGTTTCCGACATCAACGTCGGCATCCTCTACCTGTTCGCGATCAGCTCGCTCGGCGTCT
ACGGCATCATCATGGGCGGCTGGGCCTCGAACTCGAAGTACCCGTTCCTGGGCTCGCTCCGTTCGGCCGCGCAGATGGTG
TCCTACGAGGTCTCCATCGGCTTCATCATCATCACGGTGATCCTGCTGGCGGGCTCGATGAACCTGCAGCAGATCGTGGC
CAGCCAGACCGGGGGCTTCTGGAACTGGTACGTCTTCGGCGGCCCGGGCGGCCTCGCCAAGCTGCCGCTGCTGCTGGTGA
TGGTCCCGATGGCGGTGATCTTCTTCATCTCGGGCCTGGCCGAGACGAACCGCCCGCCGTTCGACCTGCCCGAGGCCGAG
TCCGAGCTCGTCGCCGGCTATCAGGTCGAGTACTCCTCGACCCCGTACCTGCTGTTCATGATCGGCGAATACGCCAACAT
CGTGCTGATCTGCGCGATGACCACCATCCTGTTCTTCGGCGGATGGTCGGCGCCGTTCCCCAGCGACTTCACGGACTCCT
GGGCGCCCACGGCGGCCAGCTTCTACTACTTCATGTGGTTCTTCCTGAAGGTCATCTTCTTCTTCTTCCTGGTCTCCATG
GCCAAGGCGATCGTGCCCCGCTACCGGTACGACCAGCTGATGCGGCTGGGGTGGAAGGTGTTCCTGCCGTTCTCGCTCGT
CTGCGTCGCGCTGATCGCGGCCTGGCGGGTGTTCGGACCCGCGGCGGCGGCATGA

Upstream 100 bases:

>100_bases
GAAGAACTTCTACCTGACCAACCCCATCGCCCGCGCCAGCGTGACGATGGCCGAATGCGCCGCGCTCGCGGCCGGCGCCA
CGAAGATCGCGGCGGAGTAG

Downstream 100 bases:

>100_bases
GGACCGTTCCGGCCATGCTCCTGACCCTCGCCCTGGCGGCGTGCGCGACCGCGCCCGCCCAGCGCGAGGGCGGCCTGGCC
ACCTACGACGCTCTTCGCGA

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MMDPAATSFWATPVGWTLVTAGQILAVMIWILLSLAFLLLADRKIWAGVQMRKGPNVVGPFGLLQSFADFLKFVLKEIVI
PSGADKTVFLLAPLISFTLAFAAWAVIPLAPGWVVSDINVGILYLFAISSLGVYGIIMGGWASNSKYPFLGSLRSAAQMV
SYEVSIGFIIITVILLAGSMNLQQIVASQTGGFWNWYVFGGPGGLAKLPLLLVMVPMAVIFFISGLAETNRPPFDLPEAE
SELVAGYQVEYSSTPYLLFMIGEYANIVLICAMTTILFFGGWSAPFPSDFTDSWAPTAASFYYFMWFFLKVIFFFFLVSM
AKAIVPRYRYDQLMRLGWKVFLPFSLVCVALIAAWRVFGPAAAA

Sequences:

>Translated_364_residues
MMDPAATSFWATPVGWTLVTAGQILAVMIWILLSLAFLLLADRKIWAGVQMRKGPNVVGPFGLLQSFADFLKFVLKEIVI
PSGADKTVFLLAPLISFTLAFAAWAVIPLAPGWVVSDINVGILYLFAISSLGVYGIIMGGWASNSKYPFLGSLRSAAQMV
SYEVSIGFIIITVILLAGSMNLQQIVASQTGGFWNWYVFGGPGGLAKLPLLLVMVPMAVIFFISGLAETNRPPFDLPEAE
SELVAGYQVEYSSTPYLLFMIGEYANIVLICAMTTILFFGGWSAPFPSDFTDSWAPTAASFYYFMWFFLKVIFFFFLVSM
AKAIVPRYRYDQLMRLGWKVFLPFSLVCVALIAAWRVFGPAAAA
>Mature_364_residues
MMDPAATSFWATPVGWTLVTAGQILAVMIWILLSLAFLLLADRKIWAGVQMRKGPNVVGPFGLLQSFADFLKFVLKEIVI
PSGADKTVFLLAPLISFTLAFAAWAVIPLAPGWVVSDINVGILYLFAISSLGVYGIIMGGWASNSKYPFLGSLRSAAQMV
SYEVSIGFIIITVILLAGSMNLQQIVASQTGGFWNWYVFGGPGGLAKLPLLLVMVPMAVIFFISGLAETNRPPFDLPEAE
SELVAGYQVEYSSTPYLLFMIGEYANIVLICAMTTILFFGGWSAPFPSDFTDSWAPTAASFYYFMWFFLKVIFFFFLVSM
AKAIVPRYRYDQLMRLGWKVFLPFSLVCVALIAAWRVFGPAAAA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family

Homologues:

Organism=Homo sapiens, GI251831107, Length=316, Percent_Identity=41.1392405063291, Blast_Score=228, Evalue=5e-60,
Organism=Escherichia coli, GI1788618, Length=340, Percent_Identity=38.8235294117647, Blast_Score=237, Evalue=7e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOH_PHEZH (B4RCM1)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002130637.1
- GeneID:   6791310
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c1797
- HOGENOM:   HBG727670
- OMA:   FMVEYGS
- ProtClustDB:   PRK06076
- HAMAP:   MF_01350
- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086
- PANTHER:   PTHR11432

Pfam domain/function: PF00146 NADHdh

EC number: =1.6.99.5

Molecular weight: Translated: 39974; Mature: 39974

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS00667 COMPLEX1_ND1_1; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x21cc4690)-; HASH(0x2178dcc0)-; HASH(0x21bec488)-; HASH(0x1fca5954)-; HASH(0x21980144)-; HASH(0x21b3bd28)-; HASH(0x21c18914)-; HASH(0x1f774f78)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDPAATSFWATPVGWTLVTAGQILAVMIWILLSLAFLLLADRKIWAGVQMRKGPNVVGP
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEECCCCCCCCH
FGLLQSFADFLKFVLKEIVIPSGADKTVFLLAPLISFTLAFAAWAVIPLAPGWVVSDINV
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCH
GILYLFAISSLGVYGIIMGGWASNSKYPFLGSLRSAAQMVSYEVSIGFIIITVILLAGSM
HHHHHHHHHHCCHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NLQQIVASQTGGFWNWYVFGGPGGLAKLPLLLVMVPMAVIFFISGLAETNRPPFDLPEAE
CHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
SELVAGYQVEYSSTPYLLFMIGEYANIVLICAMTTILFFGGWSAPFPSDFTDSWAPTAAS
HHHHCCEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
FYYFMWFFLKVIFFFFLVSMAKAIVPRYRYDQLMRLGWKVFLPFSLVCVALIAAWRVFGP
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AAAA
CCCH
>Mature Secondary Structure
MMDPAATSFWATPVGWTLVTAGQILAVMIWILLSLAFLLLADRKIWAGVQMRKGPNVVGP
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEECCCCCCCCH
FGLLQSFADFLKFVLKEIVIPSGADKTVFLLAPLISFTLAFAAWAVIPLAPGWVVSDINV
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCH
GILYLFAISSLGVYGIIMGGWASNSKYPFLGSLRSAAQMVSYEVSIGFIIITVILLAGSM
HHHHHHHHHHCCHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NLQQIVASQTGGFWNWYVFGGPGGLAKLPLLLVMVPMAVIFFISGLAETNRPPFDLPEAE
CHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
SELVAGYQVEYSSTPYLLFMIGEYANIVLICAMTTILFFGGWSAPFPSDFTDSWAPTAAS
HHHHCCEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
FYYFMWFFLKVIFFFFLVSMAKAIVPRYRYDQLMRLGWKVFLPFSLVCVALIAAWRVFGP
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AAAA
CCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA