Click here to switch to the map view.

The map label for this gene is nuoG [H]

Identifier: 197105261

GI number: 197105261

Start: 2012551

End: 2014590

Strand: Reverse

Name: nuoG [H]

Synonym: PHZ_c1798

Alternate gene names: 197105261

Gene position: 2014590-2012551 (Counterclockwise)

Preceding gene: 197105262

Following gene: 197105260

Centisome position: 50.41

GC content: 69.75

Gene sequence:

>2040_bases
ATGCCTATCGCCAAGGTCGACGGGGTCGAGGTCGAGTTCGAGCCGGGGATGAACGTCCTCCAGGTCTGCGAGCTCGCCGG
CAAGGAGATCCCGCGCTTCTGCTACCACGAGCGGCTGTCGATCGCCGGCAACTGCCGCATGTGCCTCGTCGAGGTGAAGC
CCGGTCCGCCGAAGCCGCAGGCGTCGTGCGCGCTGCCCGCCGCGGAAGGCCAGGAGATCTTCACTGACACGCCGATGGTG
AAGAAGGCCCGCCACGGGGTGATGGAGTTCCTGCTCATCAACCACCCGCTGGACTGCCCGATCTGTGACCAGGGCGGCGA
GTGCGACCTGCAGGACCAGGCCATGGGCTATGGCCGCGACGATTCCCGCTACCAGGAGAACAAGCGGGCCGTCGAAGAGA
AGTACATGGGTCCGCTCATCAAGACGGTGATGACCCGCTGCATCCAGTGCACCCGCTGCGTGCGCTTTATCACGGAAGTC
GCCGGCGTTCCCGACATCGGTCTCATCTCCCGCGGCGAAGACGTTGAAATCACGACATATCTCGACAAGGCGGTGGGCTC
TGAGCTGTCCGCCAACGTCATCGACCTGTGCCCGGTCGGCGCGCTGACCCACAAGCCGTGGGCGTTCAACTACCGCCCGT
GGGAACTGAAGAAGACCGAGACCGTCGACGTCATGGACGCGCTGGGCTCGGCGATCCGGGTCGACAGCCGCGGTCCGGCC
GTGCTGCGCGTGCTGCCGCGCACCAACGACGAGATCAACGAGGAGTGGATCTCGGACAAGACCCGCTACGCCATCGACGG
CTTGGCCCGCCAGCGTCTCGACCGGCCCTACATCCGCGAGAACGGCAAGCTGCGCGCCGCGAGCTGGGGCGAGGCCCTGG
ACACGGTCGCCGCGAAGCTGAAGGCGGCCGCCCCCGAGCGCGTCGGCGTGATCGCCGGCGACCTGCAGGACGCCGAGTCG
ATGAAGGCCGCGCTCGACCTGTTCGGCGGCATGGGCGTGACCAGCCTGGACTGCCGCCAGGACGGCATGGTGCTGGGCGA
GGGGCCGCGCGAGAGCTGGCTGTTCAACTCGACCATCGCCGGCATCGAGAACGCCGACGTGGTGCTGATCGTGGGCGCCA
ATCCGCGGATCGAGGCCCCGGTGCTGAACGCGCGCCTGCGCAAGCGCTGGCTGGCCGGCGCGCTGCGGGTGGGCGTGATC
GGCGAAGCCGCCGACCTGACCTACGACTACGAGTTCCTGGGCGCGGGCCCGGCTTCGCTGACCGGCCTGTCGAAGTCGAA
GAGCGACTTCGTAAAGGCGCTCAAGGAGGCCAAGGCGCCGGCGATCATCGTCGGGACAGGGGCCCTGGGCCGCGCCGACA
GCGCCGCGGTGCTGCAGGCCGCCGCCGGCGTCGCCAAGACGTTCGGCATGACCTGGAACGTGCTGCACACCGCTGCCTCG
CGGGTGGGCGGCCTGGACCTGGGCTTCACGCCCAAGGCGGGCGGCAAGCCGGCGCGCGAGCTGGCCCAGAAGGGCGCGGC
GGACGTCCTCTTCCTGCTGGGCGCGGATGAGCTCGACCTGTCGAAGTCCGACGCCTTCGTCGTCTATCTGGGGACTCACG
GCGACGCCGGCGCGCACCGCGCCGACGTGATCCTGCCGGGCGCCGCCTACACCGAGAAGAACGGCGTCTACGTGAACACC
GAGGGCCGCGTGCAGCTCGGCCTGCGCTCGGTGTTCCCGAAGGGCGAGGCGCGCGAGGACTGGGCGATCCTGCGGGCGCT
GTCCGAGCGGCTGGGCGCCACGCTGCCGTACGACACCCTCGACCAGCTGCGCGCCAAGCTGTTCGCCGACCATCCGACCT
TCGGCCGCATCGACTACGTGCCCGAGGCGCCGGCGGCGCTGGACTTCGGCGCGCTGGGCGCGAAGGGCGAGGTCTCGGAC
GACCCGTTCTGGAGCGGCGTGAAGAACTTCTACCTGACCAACCCCATCGCCCGCGCCAGCGTGACGATGGCCGAATGCGC
CGCGCTCGCGGCCGGCGCCACGAAGATCGCGGCGGAGTAG

Upstream 100 bases:

>100_bases
CTTCCGCCACTTCCGCCACGAGGTGGAGGAGCGGATCACCAGTTACCGCGCGCGCAAGGGCTCGTACGCCGGCGCTTCCA
TCGCGGCGGAGTAAGCGAGA

Downstream 100 bases:

>100_bases
TTGATGGACCCGGCTGCCACCTCCTTCTGGGCCACCCCCGTCGGCTGGACCCTGGTCACCGCCGGCCAGATCCTGGCCGT
GATGATCTGGATCCTGCTGT

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I, chain 3; NDH-1, chain 3 [H]

Number of amino acids: Translated: 679; Mature: 678

Protein sequence:

>679_residues
MPIAKVDGVEVEFEPGMNVLQVCELAGKEIPRFCYHERLSIAGNCRMCLVEVKPGPPKPQASCALPAAEGQEIFTDTPMV
KKARHGVMEFLLINHPLDCPICDQGGECDLQDQAMGYGRDDSRYQENKRAVEEKYMGPLIKTVMTRCIQCTRCVRFITEV
AGVPDIGLISRGEDVEITTYLDKAVGSELSANVIDLCPVGALTHKPWAFNYRPWELKKTETVDVMDALGSAIRVDSRGPA
VLRVLPRTNDEINEEWISDKTRYAIDGLARQRLDRPYIRENGKLRAASWGEALDTVAAKLKAAAPERVGVIAGDLQDAES
MKAALDLFGGMGVTSLDCRQDGMVLGEGPRESWLFNSTIAGIENADVVLIVGANPRIEAPVLNARLRKRWLAGALRVGVI
GEAADLTYDYEFLGAGPASLTGLSKSKSDFVKALKEAKAPAIIVGTGALGRADSAAVLQAAAGVAKTFGMTWNVLHTAAS
RVGGLDLGFTPKAGGKPARELAQKGAADVLFLLGADELDLSKSDAFVVYLGTHGDAGAHRADVILPGAAYTEKNGVYVNT
EGRVQLGLRSVFPKGEAREDWAILRALSERLGATLPYDTLDQLRAKLFADHPTFGRIDYVPEAPAALDFGALGAKGEVSD
DPFWSGVKNFYLTNPIARASVTMAECAALAAGATKIAAE

Sequences:

>Translated_679_residues
MPIAKVDGVEVEFEPGMNVLQVCELAGKEIPRFCYHERLSIAGNCRMCLVEVKPGPPKPQASCALPAAEGQEIFTDTPMV
KKARHGVMEFLLINHPLDCPICDQGGECDLQDQAMGYGRDDSRYQENKRAVEEKYMGPLIKTVMTRCIQCTRCVRFITEV
AGVPDIGLISRGEDVEITTYLDKAVGSELSANVIDLCPVGALTHKPWAFNYRPWELKKTETVDVMDALGSAIRVDSRGPA
VLRVLPRTNDEINEEWISDKTRYAIDGLARQRLDRPYIRENGKLRAASWGEALDTVAAKLKAAAPERVGVIAGDLQDAES
MKAALDLFGGMGVTSLDCRQDGMVLGEGPRESWLFNSTIAGIENADVVLIVGANPRIEAPVLNARLRKRWLAGALRVGVI
GEAADLTYDYEFLGAGPASLTGLSKSKSDFVKALKEAKAPAIIVGTGALGRADSAAVLQAAAGVAKTFGMTWNVLHTAAS
RVGGLDLGFTPKAGGKPARELAQKGAADVLFLLGADELDLSKSDAFVVYLGTHGDAGAHRADVILPGAAYTEKNGVYVNT
EGRVQLGLRSVFPKGEAREDWAILRALSERLGATLPYDTLDQLRAKLFADHPTFGRIDYVPEAPAALDFGALGAKGEVSD
DPFWSGVKNFYLTNPIARASVTMAECAALAAGATKIAAE
>Mature_678_residues
PIAKVDGVEVEFEPGMNVLQVCELAGKEIPRFCYHERLSIAGNCRMCLVEVKPGPPKPQASCALPAAEGQEIFTDTPMVK
KARHGVMEFLLINHPLDCPICDQGGECDLQDQAMGYGRDDSRYQENKRAVEEKYMGPLIKTVMTRCIQCTRCVRFITEVA
GVPDIGLISRGEDVEITTYLDKAVGSELSANVIDLCPVGALTHKPWAFNYRPWELKKTETVDVMDALGSAIRVDSRGPAV
LRVLPRTNDEINEEWISDKTRYAIDGLARQRLDRPYIRENGKLRAASWGEALDTVAAKLKAAAPERVGVIAGDLQDAESM
KAALDLFGGMGVTSLDCRQDGMVLGEGPRESWLFNSTIAGIENADVVLIVGANPRIEAPVLNARLRKRWLAGALRVGVIG
EAADLTYDYEFLGAGPASLTGLSKSKSDFVKALKEAKAPAIIVGTGALGRADSAAVLQAAAGVAKTFGMTWNVLHTAASR
VGGLDLGFTPKAGGKPARELAQKGAADVLFLLGADELDLSKSDAFVVYLGTHGDAGAHRADVILPGAAYTEKNGVYVNTE
GRVQLGLRSVFPKGEAREDWAILRALSERLGATLPYDTLDQLRAKLFADHPTFGRIDYVPEAPAALDFGALGAKGEVSDD
PFWSGVKNFYLTNPIARASVTMAECAALAAGATKIAAE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=694, Percent_Identity=52.5936599423631, Blast_Score=692, Evalue=0.0,
Organism=Escherichia coli, GI145693161, Length=705, Percent_Identity=27.8014184397163, Blast_Score=195, Evalue=9e-51,
Organism=Caenorhabditis elegans, GI17565758, Length=679, Percent_Identity=50.3681885125184, Blast_Score=642, Evalue=0.0,
Organism=Caenorhabditis elegans, GI32566231, Length=595, Percent_Identity=52.436974789916, Blast_Score=590, Evalue=1e-169,
Organism=Caenorhabditis elegans, GI193209088, Length=248, Percent_Identity=62.5, Blast_Score=334, Evalue=8e-92,
Organism=Drosophila melanogaster, GI24640559, Length=681, Percent_Identity=50.9544787077827, Blast_Score=637, Evalue=0.0,
Organism=Drosophila melanogaster, GI24640557, Length=681, Percent_Identity=50.9544787077827, Blast_Score=637, Evalue=0.0,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 72860; Mature: 72729

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIAKVDGVEVEFEPGMNVLQVCELAGKEIPRFCYHERLSIAGNCRMCLVEVKPGPPKPQ
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCC
ASCALPAAEGQEIFTDTPMVKKARHGVMEFLLINHPLDCPICDQGGECDLQDQAMGYGRD
CCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCC
DSRYQENKRAVEEKYMGPLIKTVMTRCIQCTRCVRFITEVAGVPDIGLISRGEDVEITTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEEEH
LDKAVGSELSANVIDLCPVGALTHKPWAFNYRPWELKKTETVDVMDALGSAIRVDSRGPA
HHHHHCCCCCCCEEEECCCCCCCCCCEECCCCCCCCCCCCHHHHHHHCCHHEEECCCCCE
VLRVLPRTNDEINEEWISDKTRYAIDGLARQRLDRPYIRENGKLRAASWGEALDTVAAKL
EEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCHHHCCCCEEECCHHHHHHHHHHHH
KAAAPERVGVIAGDLQDAESMKAALDLFGGMGVTSLDCRQDGMVLGEGPRESWLFNSTIA
HHCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCEECCCCCCEEEECCCCCCEEECCHHC
GIENADVVLIVGANPRIEAPVLNARLRKRWLAGALRVGVIGEAADLTYDYEFLGAGPASL
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCEECCHHCCEECCCEECCCCHHH
TGLSKSKSDFVKALKEAKAPAIIVGTGALGRADSAAVLQAAAGVAKTFGMTWNVLHTAAS
CCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHH
RVGGLDLGFTPKAGGKPARELAQKGAADVLFLLGADELDLSKSDAFVVYLGTHGDAGAHR
HCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCC
ADVILPGAAYTEKNGVYVNTEGRVQLGLRSVFPKGEAREDWAILRALSERLGATLPYDTL
CEEEECCCCEECCCCEEECCCCCEEECHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHH
DQLRAKLFADHPTFGRIDYVPEAPAALDFGALGAKGEVSDDPFWSGVKNFYLTNPIARAS
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHEECCCHHHHH
VTMAECAALAAGATKIAAE
HHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
PIAKVDGVEVEFEPGMNVLQVCELAGKEIPRFCYHERLSIAGNCRMCLVEVKPGPPKPQ
CCCCCCCEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCC
ASCALPAAEGQEIFTDTPMVKKARHGVMEFLLINHPLDCPICDQGGECDLQDQAMGYGRD
CCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCC
DSRYQENKRAVEEKYMGPLIKTVMTRCIQCTRCVRFITEVAGVPDIGLISRGEDVEITTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEEEH
LDKAVGSELSANVIDLCPVGALTHKPWAFNYRPWELKKTETVDVMDALGSAIRVDSRGPA
HHHHHCCCCCCCEEEECCCCCCCCCCEECCCCCCCCCCCCHHHHHHHCCHHEEECCCCCE
VLRVLPRTNDEINEEWISDKTRYAIDGLARQRLDRPYIRENGKLRAASWGEALDTVAAKL
EEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCHHHCCCCEEECCHHHHHHHHHHHH
KAAAPERVGVIAGDLQDAESMKAALDLFGGMGVTSLDCRQDGMVLGEGPRESWLFNSTIA
HHCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCEECCCCCCEEEECCCCCCEEECCHHC
GIENADVVLIVGANPRIEAPVLNARLRKRWLAGALRVGVIGEAADLTYDYEFLGAGPASL
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCEECCHHCCEECCCEECCCCHHH
TGLSKSKSDFVKALKEAKAPAIIVGTGALGRADSAAVLQAAAGVAKTFGMTWNVLHTAAS
CCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHH
RVGGLDLGFTPKAGGKPARELAQKGAADVLFLLGADELDLSKSDAFVVYLGTHGDAGAHR
HCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCC
ADVILPGAAYTEKNGVYVNTEGRVQLGLRSVFPKGEAREDWAILRALSERLGATLPYDTL
CEEEECCCCEECCCCEEECCCCCEEECHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHH
DQLRAKLFADHPTFGRIDYVPEAPAALDFGALGAKGEVSDDPFWSGVKNFYLTNPIARAS
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHEECCCHHHHH
VTMAECAALAAGATKIAAE
HHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1605643; 8422400 [H]