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The map label for this gene is nuoN [H]

Identifier: 197105254

GI number: 197105254

Start: 2004600

End: 2006030

Strand: Reverse

Name: nuoN [H]

Synonym: PHZ_c1791

Alternate gene names: 197105254

Gene position: 2006030-2004600 (Counterclockwise)

Preceding gene: 197105255

Following gene: 197105253

Centisome position: 50.2

GC content: 71.14

Gene sequence:

>1431_bases
ATGAACTTCGCCTCTGACCTCTCGCTCGCCTTTCCCGAGCTGATCCTCGCCGGCGGCGCCCTGATCCTGCTGGTGATCGG
CGCCTTCGCGCCGCGCGCCACCGCGGCCGTCTCCGCGGCCGCCGTCGTGGCGCTCCTGGGCGCGGCCGTGGCCGCGGCGA
CCCAGCCGTTCGGCGTGGCCTTCGGCGGCGGGCTGATCTCGGACGCCGCCGCGACCTTCTCGAAGGTGGCGATCTACGTC
GCCTCGGCCGTCGCCATCCCGCTGGCCCAGCCCTGGTTCGAGCGCCGCGGCATTCGCACGTTCGAGTTCCCGGTCCTGAT
CCTGCTGGCCGCCCTCGGCATGGGCATGATGGCCTCGTCGGGCGACCTGATCTCGCTGTACGTCGGCGTCGAGCTGCACT
CGCTGGCGCTCTACGTCATGGCCGCCATGCACCGGGACAACGCCAAGGCGTCCGAGGCGGGCCTGAAGTACTTCGTCCTC
GGGTCGCTCTCTTCGGGCCTGCTGCTGTACGGCGCGAGCCTGGTCTACGGCTTCGCCGGCTCGACCCTCTATTCCGAGAT
CGCGGTCGCCGTGCAGGGCGGGGCGGGCGTCGGGGCGCTGTTCGGCCTGGTGTTCGTGATCTGCGGCCTGGCCTTCAAGG
TGTCGGCGGCGCCGTTCCACATGTGGACGCCCGACGTCTATGAGGGCGCGCCGACCCCGGTCGTGGCGTTCTTCGCCGCC
GCGCCGAAGCTCGCCGCCATGGTGCTGTTCGCCCGCGCCCTGGCCGAGGCCTTCCCGGGCGCCACGGACCAGTGGCAGCA
GGTGCTGGTCGCCATCGCGCTGATCTCGATCGCCGTGGGCGCCTTCGCGGGCCTGGTCCAGAAGAACCTCAAGCGCCTGT
GGGCCTATTCCTCGATCGCCAACATCGGCTACGCGCTGCTGGGCCTGTCGGCCGGCACCGAGGCGGGCATCCAGGCCATG
CTGATCTTCATGGTCCTCTACATGATCGACGTGACGGGCTTCTTCGCCTGCCTCGCGGCGCTGTCGCGCCAGGGCCGGCC
GATGGAGACGATCGACGACATGGCGGGCCTCATCAAGGAACAGCCGGGCCTGGCGCTCGCCATGACCGCCTTCGCCCTCT
CGGCCCTCGGCCTGCCGCCGTTCTCGGGCTTCTGGGCCAAGGTCTTCGTGTTCCAGGCTGCGCTGGACGCCGGCCTCTGG
GGCCCCGCCGTGGCGGGCCTGGTGGGCTCGGTCGTGGCCGCGTTCTACTACCTGCGCCTCCTGAAGGTGATGTGGTTCGA
CGCGAGCGCGGGGACGACCGACAAGCCGGCGTTCGAGGCGCGGGGAACGGCGATCGCGCTGGGCCTCTTCTCCTTCCCCG
TGGTGCTCGTGGCCCTGGTCTGGATCTACCCGGCCGCCGGCCAGGCCGCGCGCGCCTTCGGCCTGTCCTAA

Upstream 100 bases:

>100_bases
CTGGGCGTCCAGCCCAACGTCGTCTTCGACCTGACCGCGGCCTCGGTGGACCAGCTCGTCGCTGCCTACCAGGCGGCCGT
CGGCGGGTGAGGGATCCTGG

Downstream 100 bases:

>100_bases
GGGCTTGGCCGAGCACCCGCCGATCGAGGCCTACGAGGCGCTCGACTCCACCAACGCCGAGGCCCGCCGCCGGGCCGAGG
CGGGCGAGGCGGGGCCCGTC

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MNFASDLSLAFPELILAGGALILLVIGAFAPRATAAVSAAAVVALLGAAVAAATQPFGVAFGGGLISDAAATFSKVAIYV
ASAVAIPLAQPWFERRGIRTFEFPVLILLAALGMGMMASSGDLISLYVGVELHSLALYVMAAMHRDNAKASEAGLKYFVL
GSLSSGLLLYGASLVYGFAGSTLYSEIAVAVQGGAGVGALFGLVFVICGLAFKVSAAPFHMWTPDVYEGAPTPVVAFFAA
APKLAAMVLFARALAEAFPGATDQWQQVLVAIALISIAVGAFAGLVQKNLKRLWAYSSIANIGYALLGLSAGTEAGIQAM
LIFMVLYMIDVTGFFACLAALSRQGRPMETIDDMAGLIKEQPGLALAMTAFALSALGLPPFSGFWAKVFVFQAALDAGLW
GPAVAGLVGSVVAAFYYLRLLKVMWFDASAGTTDKPAFEARGTAIALGLFSFPVVLVALVWIYPAAGQAARAFGLS

Sequences:

>Translated_476_residues
MNFASDLSLAFPELILAGGALILLVIGAFAPRATAAVSAAAVVALLGAAVAAATQPFGVAFGGGLISDAAATFSKVAIYV
ASAVAIPLAQPWFERRGIRTFEFPVLILLAALGMGMMASSGDLISLYVGVELHSLALYVMAAMHRDNAKASEAGLKYFVL
GSLSSGLLLYGASLVYGFAGSTLYSEIAVAVQGGAGVGALFGLVFVICGLAFKVSAAPFHMWTPDVYEGAPTPVVAFFAA
APKLAAMVLFARALAEAFPGATDQWQQVLVAIALISIAVGAFAGLVQKNLKRLWAYSSIANIGYALLGLSAGTEAGIQAM
LIFMVLYMIDVTGFFACLAALSRQGRPMETIDDMAGLIKEQPGLALAMTAFALSALGLPPFSGFWAKVFVFQAALDAGLW
GPAVAGLVGSVVAAFYYLRLLKVMWFDASAGTTDKPAFEARGTAIALGLFSFPVVLVALVWIYPAAGQAARAFGLS
>Mature_476_residues
MNFASDLSLAFPELILAGGALILLVIGAFAPRATAAVSAAAVVALLGAAVAAATQPFGVAFGGGLISDAAATFSKVAIYV
ASAVAIPLAQPWFERRGIRTFEFPVLILLAALGMGMMASSGDLISLYVGVELHSLALYVMAAMHRDNAKASEAGLKYFVL
GSLSSGLLLYGASLVYGFAGSTLYSEIAVAVQGGAGVGALFGLVFVICGLAFKVSAAPFHMWTPDVYEGAPTPVVAFFAA
APKLAAMVLFARALAEAFPGATDQWQQVLVAIALISIAVGAFAGLVQKNLKRLWAYSSIANIGYALLGLSAGTEAGIQAM
LIFMVLYMIDVTGFFACLAALSRQGRPMETIDDMAGLIKEQPGLALAMTAFALSALGLPPFSGFWAKVFVFQAALDAGLW
GPAVAGLVGSVVAAFYYLRLLKVMWFDASAGTTDKPAFEARGTAIALGLFSFPVVLVALVWIYPAAGQAARAFGLS

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Escherichia coli, GI145693160, Length=404, Percent_Identity=35.1485148514851, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1788831, Length=297, Percent_Identity=26.9360269360269, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788613, Length=281, Percent_Identity=25.9786476868327, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788829, Length=294, Percent_Identity=27.891156462585, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788614, Length=313, Percent_Identity=26.8370607028754, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 49103; Mature: 49103

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFASDLSLAFPELILAGGALILLVIGAFAPRATAAVSAAAVVALLGAAVAAATQPFGVA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
FGGGLISDAAATFSKVAIYVASAVAIPLAQPWFERRGIRTFEFPVLILLAALGMGMMASS
ECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCC
GDLISLYVGVELHSLALYVMAAMHRDNAKASEAGLKYFVLGSLSSGLLLYGASLVYGFAG
CCEEEEEECHHHHHHHHHHHHHHHCCCCCHHHCCCEEEEECCCCCCHHHHHHHHHHHHCC
STLYSEIAVAVQGGAGVGALFGLVFVICGLAFKVSAAPFHMWTPDVYEGAPTPVVAFFAA
HHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCHHHHHHHH
APKLAAMVLFARALAEAFPGATDQWQQVLVAIALISIAVGAFAGLVQKNLKRLWAYSSIA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIGYALLGLSAGTEAGIQAMLIFMVLYMIDVTGFFACLAALSRQGRPMETIDDMAGLIKE
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
QPGLALAMTAFALSALGLPPFSGFWAKVFVFQAALDAGLWGPAVAGLVGSVVAAFYYLRL
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LKVMWFDASAGTTDKPAFEARGTAIALGLFSFPVVLVALVWIYPAAGQAARAFGLS
HHHHHCCCCCCCCCCCCHHHCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHCCCC
>Mature Secondary Structure
MNFASDLSLAFPELILAGGALILLVIGAFAPRATAAVSAAAVVALLGAAVAAATQPFGVA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
FGGGLISDAAATFSKVAIYVASAVAIPLAQPWFERRGIRTFEFPVLILLAALGMGMMASS
ECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCC
GDLISLYVGVELHSLALYVMAAMHRDNAKASEAGLKYFVLGSLSSGLLLYGASLVYGFAG
CCEEEEEECHHHHHHHHHHHHHHHCCCCCHHHCCCEEEEECCCCCCHHHHHHHHHHHHCC
STLYSEIAVAVQGGAGVGALFGLVFVICGLAFKVSAAPFHMWTPDVYEGAPTPVVAFFAA
HHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCHHHHHHHH
APKLAAMVLFARALAEAFPGATDQWQQVLVAIALISIAVGAFAGLVQKNLKRLWAYSSIA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIGYALLGLSAGTEAGIQAMLIFMVLYMIDVTGFFACLAALSRQGRPMETIDDMAGLIKE
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
QPGLALAMTAFALSALGLPPFSGFWAKVFVFQAALDAGLWGPAVAGLVGSVVAAFYYLRL
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LKVMWFDASAGTTDKPAFEARGTAIALGLFSFPVVLVALVWIYPAAGQAARAFGLS
HHHHHCCCCCCCCCCCCHHHCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA