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The map label for this gene is pyrH [H]

Identifier: 197105241

GI number: 197105241

Start: 1988725

End: 1989444

Strand: Reverse

Name: pyrH [H]

Synonym: PHZ_c1778

Alternate gene names: 197105241

Gene position: 1989444-1988725 (Counterclockwise)

Preceding gene: 197105242

Following gene: 197105240

Centisome position: 49.78

GC content: 67.92

Gene sequence:

>720_bases
ATGACCGACGCCAAACCGCGCTACAACCGAGTGCTCCTGAAGGTGTCGGGCGAAGTCCTGATGGGCGACCAGCCGTTCGG
AATCGACACGGGGACCCTCGAGCGCACGGCCGAGGACATCGCCGAGGTGGTCCGCACGGGCGTCCAGCTCTGCCTCGTGA
TCGGCGGCGGCAACATCTTCCGCGGCGTGTCCCTGGCGGGGCGCGGCATGGAACGGGCCAGCGCCGACTACATGGGCATG
CTGGCGACGGTCATGAATGCCCTGGCGCTGCAGGCGGCGCTGGAGAAGATCGGCGTCTACACCCGCGTGCAGTCGGCCAT
TCCGATGGAAGCGGTGTGCGAGCCCTACATCCGCCGTCGCGCCATCCGCCATCTCGAGAAGGGCCGGGTGGTGATCTTCG
CCGCCGGCGTGGGCGCGCCGTTCTTCACGACGGACTCCGGCGCGGCCCTGCGCGCGGCCGAAATGGGCTGCGAGGCGCTG
TTCAAGGGCACCAGCGTGGACGGCGTCTACACCGCCGACCCCAAGAAGGATCCCGACGCGCAGCGCTACGACACGCTGAG
CTACACCGACGTGCTCGCCAAGGACCTGCGCGTCATGGACGCCTCGGCCGTGAGCCTGATGCGCGACAACCAGATTCCCA
TCGTGGTCTTCTCGATCCGCGAGCGGGGCAATTTCCTCAAGGTGCTGAAGGGCGAGGGCGTCTACACGACGATCGCCTGA

Upstream 100 bases:

>100_bases
TAGGCGTTCGCCTGAAAGAGCCTTCAGGGGCGCGGCGCGTTCGACGCGCGCCGCGCCCTTGATGTATCTACCTTCCGCGT
ACCAGAATCCCGGACCCGCC

Downstream 100 bases:

>100_bases
CGGCTTAGTTTCGATCCGAACAGACTTCGCACGGGAGAGATCCGCATGGCCACGACCGAGAAGCCGGTGCTTTCCAAGTA
CAGGGACCGCATGGACAAGG

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MTDAKPRYNRVLLKVSGEVLMGDQPFGIDTGTLERTAEDIAEVVRTGVQLCLVIGGGNIFRGVSLAGRGMERASADYMGM
LATVMNALALQAALEKIGVYTRVQSAIPMEAVCEPYIRRRAIRHLEKGRVVIFAAGVGAPFFTTDSGAALRAAEMGCEAL
FKGTSVDGVYTADPKKDPDAQRYDTLSYTDVLAKDLRVMDASAVSLMRDNQIPIVVFSIRERGNFLKVLKGEGVYTTIA

Sequences:

>Translated_239_residues
MTDAKPRYNRVLLKVSGEVLMGDQPFGIDTGTLERTAEDIAEVVRTGVQLCLVIGGGNIFRGVSLAGRGMERASADYMGM
LATVMNALALQAALEKIGVYTRVQSAIPMEAVCEPYIRRRAIRHLEKGRVVIFAAGVGAPFFTTDSGAALRAAEMGCEAL
FKGTSVDGVYTADPKKDPDAQRYDTLSYTDVLAKDLRVMDASAVSLMRDNQIPIVVFSIRERGNFLKVLKGEGVYTTIA
>Mature_238_residues
TDAKPRYNRVLLKVSGEVLMGDQPFGIDTGTLERTAEDIAEVVRTGVQLCLVIGGGNIFRGVSLAGRGMERASADYMGML
ATVMNALALQAALEKIGVYTRVQSAIPMEAVCEPYIRRRAIRHLEKGRVVIFAAGVGAPFFTTDSGAALRAAEMGCEALF
KGTSVDGVYTADPKKDPDAQRYDTLSYTDVLAKDLRVMDASAVSLMRDNQIPIVVFSIRERGNFLKVLKGEGVYTTIA

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=237, Percent_Identity=51.4767932489451, Blast_Score=245, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25833; Mature: 25702

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAKPRYNRVLLKVSGEVLMGDQPFGIDTGTLERTAEDIAEVVRTGVQLCLVIGGGNIF
CCCCCCCCCEEEEEECCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCHH
RGVSLAGRGMERASADYMGMLATVMNALALQAALEKIGVYTRVQSAIPMEAVCEPYIRRR
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AIRHLEKGRVVIFAAGVGAPFFTTDSGAALRAAEMGCEALFKGTSVDGVYTADPKKDPDA
HHHHHHCCCEEEEEECCCCCEEECCCCCCHHHHHHCHHHHHCCCCCCCEEECCCCCCCCC
QRYDTLSYTDVLAKDLRVMDASAVSLMRDNQIPIVVFSIRERGNFLKVLKGEGVYTTIA
HHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCEEEECC
>Mature Secondary Structure 
TDAKPRYNRVLLKVSGEVLMGDQPFGIDTGTLERTAEDIAEVVRTGVQLCLVIGGGNIF
CCCCCCCCEEEEEECCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCHH
RGVSLAGRGMERASADYMGMLATVMNALALQAALEKIGVYTRVQSAIPMEAVCEPYIRRR
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AIRHLEKGRVVIFAAGVGAPFFTTDSGAALRAAEMGCEALFKGTSVDGVYTADPKKDPDA
HHHHHHCCCEEEEEECCCCCEEECCCCCCHHHHHHCHHHHHCCCCCCCEEECCCCCCCCC
QRYDTLSYTDVLAKDLRVMDASAVSLMRDNQIPIVVFSIRERGNFLKVLKGEGVYTTIA
HHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]