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The map label for this gene is frr

Identifier: 197105240

GI number: 197105240

Start: 1988113

End: 1988679

Strand: Reverse

Name: frr

Synonym: PHZ_c1777

Alternate gene names: 197105240

Gene position: 1988679-1988113 (Counterclockwise)

Preceding gene: 197105241

Following gene: 197105239

Centisome position: 49.76

GC content: 65.61

Gene sequence:

>567_bases
ATGGCCACGACCGAGAAGCCGGTGCTTTCCAAGTACAGGGACCGCATGGACAAGGCCGTTGCGGCGTTGAAGGAGGAGTT
CGGCTCGCTGCGCACGGGCCGGGCCTCGGCCAGCCTGCTCGACCAGATCCACGTGGACGCCTACGGCTCGTCCATGCCGC
TGACCCAGGTGGCGGCGGTGTCCGTGCCCGAACCGAGGATGATCACAGTCAACGTCTGGGACCGCGGCATGGTGGTCTCG
GTGGAGAAGGCGATCCGCCAGTCGGACCTGGGCCTGAACCCGGTCGTCGACGGCCAGACCCTGCGGATCCCGATCCCGCC
GCTGACCGAAGAGCGCCGCAAGGACCTCGCCAAGATCGCCGGCCGCTACGCCGAGCAGCAGCGCGTGGCCGTGCGCAACA
TCCGCCGCGACGCCAACGAGGACCTGCGCAAGGCCCAGAAGGACAACGTCATCAGCCAGGACGAAGAGAAGCGGATGGAG
ACCGAGGTCCAGAAGATGACCGACGAGGCCATCAAGCGCATCGACGAAGCCTTGAAAACCAAGGAACAAGAGATCATGCA
GGTCTGA

Upstream 100 bases:

>100_bases
GGGCAATTTCCTCAAGGTGCTGAAGGGCGAGGGCGTCTACACGACGATCGCCTGACGGCTTAGTTTCGATCCGAACAGAC
TTCGCACGGGAGAGATCCGC

Downstream 100 bases:

>100_bases
CGCGCGCGTCAGCCGCCTCGTAGGATCCCCCACAGCATGGCCGCACAAGACAAGACGCCGCCTGCGTCCACGCCCCAGCC
GGGCGCGGCGGAGCGGCCCC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MATTEKPVLSKYRDRMDKAVAALKEEFGSLRTGRASASLLDQIHVDAYGSSMPLTQVAAVSVPEPRMITVNVWDRGMVVS
VEKAIRQSDLGLNPVVDGQTLRIPIPPLTEERRKDLAKIAGRYAEQQRVAVRNIRRDANEDLRKAQKDNVISQDEEKRME
TEVQKMTDEAIKRIDEALKTKEQEIMQV

Sequences:

>Translated_188_residues
MATTEKPVLSKYRDRMDKAVAALKEEFGSLRTGRASASLLDQIHVDAYGSSMPLTQVAAVSVPEPRMITVNVWDRGMVVS
VEKAIRQSDLGLNPVVDGQTLRIPIPPLTEERRKDLAKIAGRYAEQQRVAVRNIRRDANEDLRKAQKDNVISQDEEKRME
TEVQKMTDEAIKRIDEALKTKEQEIMQV
>Mature_187_residues
ATTEKPVLSKYRDRMDKAVAALKEEFGSLRTGRASASLLDQIHVDAYGSSMPLTQVAAVSVPEPRMITVNVWDRGMVVSV
EKAIRQSDLGLNPVVDGQTLRIPIPPLTEERRKDLAKIAGRYAEQQRVAVRNIRRDANEDLRKAQKDNVISQDEEKRMET
EVQKMTDEAIKRIDEALKTKEQEIMQV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=179, Percent_Identity=29.0502793296089, Blast_Score=91, Evalue=4e-19,
Organism=Homo sapiens, GI291042689, Length=156, Percent_Identity=30.1282051282051, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI1786368, Length=174, Percent_Identity=55.7471264367816, Blast_Score=191, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24661488, Length=173, Percent_Identity=31.2138728323699, Blast_Score=85, Evalue=3e-17,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_PHEZH (B4RBZ1)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002130617.1
- GeneID:   6791290
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c1777
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 21258; Mature: 21126

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTEKPVLSKYRDRMDKAVAALKEEFGSLRTGRASASLLDQIHVDAYGSSMPLTQVAAV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHC
SVPEPRMITVNVWDRGMVVSVEKAIRQSDLGLNPVVDGQTLRIPIPPLTEERRKDLAKIA
CCCCCCEEEEEECCCCEEEHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHH
GRYAEQQRVAVRNIRRDANEDLRKAQKDNVISQDEEKRMETEVQKMTDEAIKRIDEALKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEQEIMQV
HHHHHHCC
>Mature Secondary Structure 
ATTEKPVLSKYRDRMDKAVAALKEEFGSLRTGRASASLLDQIHVDAYGSSMPLTQVAAV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHC
SVPEPRMITVNVWDRGMVVSVEKAIRQSDLGLNPVVDGQTLRIPIPPLTEERRKDLAKIA
CCCCCCEEEEEECCCCEEEHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHH
GRYAEQQRVAVRNIRRDANEDLRKAQKDNVISQDEEKRMETEVQKMTDEAIKRIDEALKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEQEIMQV
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA