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The map label for this gene is fabZ [H]

Identifier: 197105232

GI number: 197105232

Start: 1979485

End: 1979955

Strand: Reverse

Name: fabZ [H]

Synonym: PHZ_c1769

Alternate gene names: 197105232

Gene position: 1979955-1979485 (Counterclockwise)

Preceding gene: 197105233

Following gene: 197105231

Centisome position: 49.55

GC content: 67.09

Gene sequence:

>471_bases
ATGACGCGTAAGGCGCCGGCGGGGCAGGACCCGACGCAGATCGACATCACCGAGGTGCTGGAGCGGATCCCGCACCGCTA
TCCGTTCCTGCTGGTGGACCGTTGCGAGGAGTACAAGCCCTCGGAGTCGATCGTCGGCATCAAGTGCGTGACGGTGAACG
AGCCCTTCTTCCAGGGGCATTTCCCGGACTATCCGGTGATGCCGGGCGTGCTGCTCATCGAGGCCATGGCCCAGACCGGC
GCGGTCCTGATGTCGAAATCGCTCGAGGTGGACACCGCCGGCAAGGCGATCTTCTTCATGTCGGCCGACAACTGCCGCTT
CCGCTCGCCGGTGCGGCCAGGCGACGTGGTGCGGATGCCGGTGCGCGTGGTCCGTCACCGCGGCGACGTCTTCAAGTTCG
CGGGTCAGGCCCTGGTGGGCGACAAGGTGGCCGCCGAGGCCGAGTTCGCCGCCATGGTCGTGGAGACCTGA

Upstream 100 bases:

>100_bases
GGGGGCATGCCCGCCCGTCCGATCCGGCACTGGCTGAAGGAAACGGCGTGGCTCGCCCGGATGGCGAACCGCAGGGGGCC
GGACGGTAAAGGGGCTGGGA

Downstream 100 bases:

>100_bases
GCGCTTGGCCGTCGAGATCCACCCCACCGCCATCGTCGCCGACAGCGCCGAGCTGGCGGACGGCGTCAGCATCGGCCCCT
TCTGCATCGTCGGCGAGGCG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MTRKAPAGQDPTQIDITEVLERIPHRYPFLLVDRCEEYKPSESIVGIKCVTVNEPFFQGHFPDYPVMPGVLLIEAMAQTG
AVLMSKSLEVDTAGKAIFFMSADNCRFRSPVRPGDVVRMPVRVVRHRGDVFKFAGQALVGDKVAAEAEFAAMVVET

Sequences:

>Translated_156_residues
MTRKAPAGQDPTQIDITEVLERIPHRYPFLLVDRCEEYKPSESIVGIKCVTVNEPFFQGHFPDYPVMPGVLLIEAMAQTG
AVLMSKSLEVDTAGKAIFFMSADNCRFRSPVRPGDVVRMPVRVVRHRGDVFKFAGQALVGDKVAAEAEFAAMVVET
>Mature_155_residues
TRKAPAGQDPTQIDITEVLERIPHRYPFLLVDRCEEYKPSESIVGIKCVTVNEPFFQGHFPDYPVMPGVLLIEAMAQTGA
VLMSKSLEVDTAGKAIFFMSADNCRFRSPVRPGDVVRMPVRVVRHRGDVFKFAGQALVGDKVAAEAEFAAMVVET

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=134, Percent_Identity=46.2686567164179, Blast_Score=124, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 17271; Mature: 17140

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKAPAGQDPTQIDITEVLERIPHRYPFLLVDRCEEYKPSESIVGIKCVTVNEPFFQGH
CCCCCCCCCCCCEECHHHHHHHCCCCCCEEEEECHHCCCCCCCEEEEEEEEECCCCCCCC
FPDYPVMPGVLLIEAMAQTGAVLMSKSLEVDTAGKAIFFMSADNCRFRSPVRPGDVVRMP
CCCCCCCCHHHHHHHHHHHCCEEHHCCCCEECCCCEEEEEECCCCEECCCCCCCCEEHHH
VRVVRHRGDVFKFAGQALVGDKVAAEAEFAAMVVET
HHHHHHCCCHHHHCCCHHHCCHHHHCCCEEEEEECC
>Mature Secondary Structure 
TRKAPAGQDPTQIDITEVLERIPHRYPFLLVDRCEEYKPSESIVGIKCVTVNEPFFQGH
CCCCCCCCCCCEECHHHHHHHCCCCCCEEEEECHHCCCCCCCEEEEEEEEECCCCCCCC
FPDYPVMPGVLLIEAMAQTGAVLMSKSLEVDTAGKAIFFMSADNCRFRSPVRPGDVVRMP
CCCCCCCCHHHHHHHHHHHCCEEHHCCCCEECCCCEEEEEECCCCEECCCCCCCCEEHHH
VRVVRHRGDVFKFAGQALVGDKVAAEAEFAAMVVET
HHHHHHCCCHHHHCCCHHHCCHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA