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The map label for this gene is lpxA [H]

Identifier: 197105231

GI number: 197105231

Start: 1978683

End: 1979480

Strand: Reverse

Name: lpxA [H]

Synonym: PHZ_c1768

Alternate gene names: 197105231

Gene position: 1979480-1978683 (Counterclockwise)

Preceding gene: 197105232

Following gene: 197105230

Centisome position: 49.53

GC content: 69.55

Gene sequence:

>798_bases
TTGGCCGTCGAGATCCACCCCACCGCCATCGTCGCCGACAGCGCCGAGCTGGCGGACGGCGTCAGCATCGGCCCCTTCTG
CATCGTCGGCGAGGCGGTGAGGATCGGCCCCGGCACGCGCCTGCACGCCCATGTCGTGGTCGAGGGGCGCACGACCCTGG
GCGCGAACAACCACGTCCATCCGTTCGCCGTCCTCGGCGGGCCGCCGCAGCACACCGCCTACAAGGGCGAGGACACCGAG
CTCGTCATCGGCGACAACAACCTGATCCGCGAACACGCCACGATGAACATCGGCACGCCGCACGGCGGGGGCGTGACGCG
CGTGGGCTCGAACGGCCTCTACATGATCGAGAGCCATGTCGGGCACGACTGCATCGTGGGCGACAACGTCATCCTGACGA
AGCAGGCCACCCTCGGGGGCCACTGCCAGATCGGCGACTATGTGATCGTGGGCGGCCTCGCAGCGGTCCACCAGTTCACC
CGCGTCGGCCGCCACGCCATGATCGGCGGCCTGGCGGCCGTGGTGAAGGACGTGATCCCCTACGGCTCGGTGTGGGGCAA
CCACGCCCATCTCGAGGGGCTGAACCTCGTGGGCCTGAAGCGGCGCGGGTTCGACCGCGAGACGATCAACACCCTGCGCG
CCGCCTACCGGCTGCTGTTCGCCGACGAGGGCACCTTCCAGGAGCGCCTGGAGGACACCGCCCAGACCTACGCCGACAGC
CCGCAGGTGATGGAGATCATCGACTTCATCCGCGCCGACGCCAGCCGGCCCCTCTGCCTGCCCGAACGCGAAGTCTGA

Upstream 100 bases:

>100_bases
CACCGCGGCGACGTCTTCAAGTTCGCGGGTCAGGCCCTGGTGGGCGACAAGGTGGCCGCCGAGGCCGAGTTCGCCGCCAT
GGTCGTGGAGACCTGAGCGC

Downstream 100 bases:

>100_bases
TGAAGAAGCTGGGGCTGATCGCCGGCGGCGGGGGCCTTCCCGTCGAGATCGCCGAGCATTGCGAACGCTCGGGCCGGCCG
CTCTTCGTCATCCGGCTGAA

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MAVEIHPTAIVADSAELADGVSIGPFCIVGEAVRIGPGTRLHAHVVVEGRTTLGANNHVHPFAVLGGPPQHTAYKGEDTE
LVIGDNNLIREHATMNIGTPHGGGVTRVGSNGLYMIESHVGHDCIVGDNVILTKQATLGGHCQIGDYVIVGGLAAVHQFT
RVGRHAMIGGLAAVVKDVIPYGSVWGNHAHLEGLNLVGLKRRGFDRETINTLRAAYRLLFADEGTFQERLEDTAQTYADS
PQVMEIIDFIRADASRPLCLPEREV

Sequences:

>Translated_265_residues
MAVEIHPTAIVADSAELADGVSIGPFCIVGEAVRIGPGTRLHAHVVVEGRTTLGANNHVHPFAVLGGPPQHTAYKGEDTE
LVIGDNNLIREHATMNIGTPHGGGVTRVGSNGLYMIESHVGHDCIVGDNVILTKQATLGGHCQIGDYVIVGGLAAVHQFT
RVGRHAMIGGLAAVVKDVIPYGSVWGNHAHLEGLNLVGLKRRGFDRETINTLRAAYRLLFADEGTFQERLEDTAQTYADS
PQVMEIIDFIRADASRPLCLPEREV
>Mature_264_residues
AVEIHPTAIVADSAELADGVSIGPFCIVGEAVRIGPGTRLHAHVVVEGRTTLGANNHVHPFAVLGGPPQHTAYKGEDTEL
VIGDNNLIREHATMNIGTPHGGGVTRVGSNGLYMIESHVGHDCIVGDNVILTKQATLGGHCQIGDYVIVGGLAAVHQFTR
VGRHAMIGGLAAVVKDVIPYGSVWGNHAHLEGLNLVGLKRRGFDRETINTLRAAYRLLFADEGTFQERLEDTAQTYADSP
QVMEIIDFIRADASRPLCLPEREV

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=254, Percent_Identity=46.8503937007874, Blast_Score=229, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018357
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 28326; Mature: 28194

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVEIHPTAIVADSAELADGVSIGPFCIVGEAVRIGPGTRLHAHVVVEGRTTLGANNHVH
CEEEECCCEEEECCHHHHCCCCCCCEEEECCEEEECCCCEEEEEEEEECCEEECCCCCCC
PFAVLGGPPQHTAYKGEDTELVIGDNNLIREHATMNIGTPHGGGVTRVGSNGLYMIESHV
EEEEECCCCCCCCCCCCCCEEEECCCCEEEHHCEEECCCCCCCCEEEECCCCEEEEECCC
GHDCIVGDNVILTKQATLGGHCQIGDYVIVGGLAAVHQFTRVGRHAMIGGLAAVVKDVIP
CCEEEECCCEEEEEECCCCCCEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YGSVWGNHAHLEGLNLVGLKRRGFDRETINTLRAAYRLLFADEGTFQERLEDTAQTYADS
CCCCCCCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHCCC
PQVMEIIDFIRADASRPLCLPEREV
CHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
AVEIHPTAIVADSAELADGVSIGPFCIVGEAVRIGPGTRLHAHVVVEGRTTLGANNHVH
EEEECCCEEEECCHHHHCCCCCCCEEEECCEEEECCCCEEEEEEEEECCEEECCCCCCC
PFAVLGGPPQHTAYKGEDTELVIGDNNLIREHATMNIGTPHGGGVTRVGSNGLYMIESHV
EEEEECCCCCCCCCCCCCCEEEECCCCEEEHHCEEECCCCCCCCEEEECCCCEEEEECCC
GHDCIVGDNVILTKQATLGGHCQIGDYVIVGGLAAVHQFTRVGRHAMIGGLAAVVKDVIP
CCEEEECCCEEEEEECCCCCCEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YGSVWGNHAHLEGLNLVGLKRRGFDRETINTLRAAYRLLFADEGTFQERLEDTAQTYADS
CCCCCCCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHCCC
PQVMEIIDFIRADASRPLCLPEREV
CHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA