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The map label for this gene is trpG [H]

Identifier: 197105222

GI number: 197105222

Start: 1968501

End: 1969091

Strand: Direct

Name: trpG [H]

Synonym: PHZ_c1759

Alternate gene names: 197105222

Gene position: 1968501-1969091 (Clockwise)

Preceding gene: 197105221

Following gene: 197105223

Centisome position: 49.26

GC content: 67.17

Gene sequence:

>591_bases
ATGATCCTGGTGATCGATAACTACGACAGCTTCACCTACAACCTGGTTCACTATCTGAACGAACTGGGGGCGGAGACGCA
TGTCGTGCGCAACGACGCGATCACCGCCGAACAGGCGCTGGCGCTGAAGCCGGAAGCGATCCTGCTGTCGCCCGGCCCCT
GCACGCCCAACGAGGCGGGCGTCTGCCTGTCGCTGCTGGCCAGCGCGCCGGCCGACCTGCCGATCTTCGGCGTCTGCCTC
GGCCACCAGTCGATCGGCCAGGCGTTCGGCGGCGAGGTGGTCCGCGCCAAGGCGCTGATGCACGGCAAGACCAGCCTGAT
CCATCACAACGGCAAGGGCGTGTTCGCCGGCCTGAAGAACCCCTTCACCGCCACGCGCTATCACAGCCTCTCGGTCGAGA
AGGCCGCCCTGCCGCCGGACCTCGAGGTCACGGCCTGGACCGACGACGGCGAGATCATGGGCGTGCAGCACAAGACCCGG
CCGATCTTCGGCGTGCAGTTCCACCCCGAGTCCATCGCCACCGAGTGCGGCCACGAGCTGCTGTCCAACTTCCTCGACAT
CGCCGGCGTGAAGCGGCTCGCCGACGCCTGA

Upstream 100 bases:

>100_bases
GCGCCCGCGCGATCGCCGCCGCATCGAGAGTCGAATCGTCAGCCGACATGGACCGAGCATCCCGCTTGGCGGACGGCTCC
GCAAAGCCTAGATGGGACGC

Downstream 100 bases:

>100_bases
GCCGCCGATGTCCGACGCCTTCAAGCCGCTCCTCTCGCGCCTGGCCGACGGCGCGACCCTGTCGGACGACGACGCCGACG
CGTTCTTCTCGGCCTGCCTC

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MILVIDNYDSFTYNLVHYLNELGAETHVVRNDAITAEQALALKPEAILLSPGPCTPNEAGVCLSLLASAPADLPIFGVCL
GHQSIGQAFGGEVVRAKALMHGKTSLIHHNGKGVFAGLKNPFTATRYHSLSVEKAALPPDLEVTAWTDDGEIMGVQHKTR
PIFGVQFHPESIATECGHELLSNFLDIAGVKRLADA

Sequences:

>Translated_196_residues
MILVIDNYDSFTYNLVHYLNELGAETHVVRNDAITAEQALALKPEAILLSPGPCTPNEAGVCLSLLASAPADLPIFGVCL
GHQSIGQAFGGEVVRAKALMHGKTSLIHHNGKGVFAGLKNPFTATRYHSLSVEKAALPPDLEVTAWTDDGEIMGVQHKTR
PIFGVQFHPESIATECGHELLSNFLDIAGVKRLADA
>Mature_196_residues
MILVIDNYDSFTYNLVHYLNELGAETHVVRNDAITAEQALALKPEAILLSPGPCTPNEAGVCLSLLASAPADLPIFGVCL
GHQSIGQAFGGEVVRAKALMHGKTSLIHHNGKGVFAGLKNPFTATRYHSLSVEKAALPPDLEVTAWTDDGEIMGVQHKTR
PIFGVQFHPESIATECGHELLSNFLDIAGVKRLADA

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=188, Percent_Identity=31.9148936170213, Blast_Score=78, Evalue=5e-15,
Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=61.0810810810811, Blast_Score=239, Evalue=1e-64,
Organism=Escherichia coli, GI1787517, Length=193, Percent_Identity=42.4870466321244, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1786215, Length=160, Percent_Identity=30, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI1788854, Length=190, Percent_Identity=26.8421052631579, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193204318, Length=137, Percent_Identity=31.3868613138686, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI133901714, Length=113, Percent_Identity=32.7433628318584, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71992717, Length=113, Percent_Identity=32.7433628318584, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71992710, Length=113, Percent_Identity=32.7433628318584, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=189, Percent_Identity=46.031746031746, Blast_Score=181, Evalue=6e-47,
Organism=Saccharomyces cerevisiae, GI6324361, Length=216, Percent_Identity=33.7962962962963, Blast_Score=100, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323873, Length=184, Percent_Identity=26.6304347826087, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 20977; Mature: 20977

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVIDNYDSFTYNLVHYLNELGAETHVVRNDAITAEQALALKPEAILLSPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHEECCCEEEECCCCCCCCCHH
VCLSLLASAPADLPIFGVCLGHQSIGQAFGGEVVRAKALMHGKTSLIHHNGKGVFAGLKN
HHHHHHHCCCCCCCEEEEEECCHHHHHHHCCHHHHHHHHHCCCCEEEEECCCEEEEECCC
PFTATRYHSLSVEKAALPPDLEVTAWTDDGEIMGVQHKTRPIFGVQFHPESIATECGHEL
CCCCCEEEECCCHHCCCCCCCEEEEECCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHH
LSNFLDIAGVKRLADA
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MILVIDNYDSFTYNLVHYLNELGAETHVVRNDAITAEQALALKPEAILLSPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHEECCCEEEECCCCCCCCCHH
VCLSLLASAPADLPIFGVCLGHQSIGQAFGGEVVRAKALMHGKTSLIHHNGKGVFAGLKN
HHHHHHHCCCCCCCEEEEEECCHHHHHHHCCHHHHHHHHHCCCCEEEEECCCEEEEECCC
PFTATRYHSLSVEKAALPPDLEVTAWTDDGEIMGVQHKTRPIFGVQFHPESIATECGHEL
CCCCCEEEECCCHHCCCCCCCEEEEECCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHH
LSNFLDIAGVKRLADA
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2105306; 10984043 [H]