Click here to switch to the map view.

The map label for this gene is trpD

Identifier: 197105223

GI number: 197105223

Start: 1969099

End: 1970112

Strand: Direct

Name: trpD

Synonym: PHZ_c1760

Alternate gene names: 197105223

Gene position: 1969099-1970112 (Clockwise)

Preceding gene: 197105222

Following gene: 197105224

Centisome position: 49.27

GC content: 73.67

Gene sequence:

>1014_bases
ATGTCCGACGCCTTCAAGCCGCTCCTCTCGCGCCTGGCCGACGGCGCGACCCTGTCGGACGACGACGCCGACGCGTTCTT
CTCGGCCTGCCTCCGGGGTGAGCCGACGCCGGCCCAGGTCGGCGCCGCCCTGACGGCCATGCGGATGCGCGGGGAGACGC
TCGGCGAGATCGCCGCCTGCGCCCGCGCCATGCGGCGAGCGGCGATCCACCTCGAGCCGCCGTTCCCCACCATCGACGTC
TGCGGCACCGGCGGCGACGGGCTGCACACGCTGAACATCTCCACCGCCGTGGGCTTCGTCGCCGCAGGCGGCGGGCTGAA
GGTGGCCAAGCACGGCAACCGGGCGATGTCGTCCAAGTCGGGCACGGCCGACGTCCTCGGCGAACTGGGCGTCAACATCG
CCGCCCCGCCCGAGAAGCAGCTCCAGGCGCTGGACGAGGCCGGCATCTGCTTCCTGTTTGCGCCGGCGCACCACAGCGCC
ATGCGTCACGTCTCGCCGATCCGGGCCGAGCTGGGCTTCCGGACGATCTTCAACCTGCTGGGGCCGCTGACCAATCCGGC
CGGCGCGCAGCGGCAGGTGGTGGGCGTCTTCGCCGAGCGCTGGGTCAAGCCGCTGGCGCAGGCGCTCGGCATGCTGGGGT
CCGAGAAGGCCTGGGTCGTCCACGGGGCCGGGCTCGACGAGCTGACCACCACGGGCGAGACCTCGGTCGCCGAGTTCTCG
GACGGCAAGGTCCGGCTGTTCACGATCACCCCGGAGGCGGTGGGCCTACGCCGCGCGGCCCTGGCCGACATCACCGGCGG
CAGCCCGGCCGAGAACGCGCAGGCGCTGCGCCGCCTGCTCGCCGGGGAGACCGGCGCCTACCGCGACATCGTCGCCCTGA
ACGCCGCCGCGGCCTTCCTGGTCGCCGACAAGGTCGAGACGCTGCGCGAGGGGGTCGAGCTGGCCGGCCGTGTCCTGGAC
GAAGGGCGCGCCCAGGCCGCCCTGGAGCGACTCGTGGAGATCACCGCCCCATGA

Upstream 100 bases:

>100_bases
TTCCACCCCGAGTCCATCGCCACCGAGTGCGGCCACGAGCTGCTGTCCAACTTCCTCGACATCGCCGGCGTGAAGCGGCT
CGCCGACGCCTGAGCCGCCG

Downstream 100 bases:

>100_bases
GCGACATCCTCGAGAAGATCGCCGCCTACAAGCGCGACGAGGTCGCCGTCCGCAAGGCCGCGCAGCCGACGATCGCGCCG
CCGGCCGAGGCCCCGCGCGG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSDAFKPLLSRLADGATLSDDDADAFFSACLRGEPTPAQVGAALTAMRMRGETLGEIAACARAMRRAAIHLEPPFPTIDV
CGTGGDGLHTLNISTAVGFVAAGGGLKVAKHGNRAMSSKSGTADVLGELGVNIAAPPEKQLQALDEAGICFLFAPAHHSA
MRHVSPIRAELGFRTIFNLLGPLTNPAGAQRQVVGVFAERWVKPLAQALGMLGSEKAWVVHGAGLDELTTTGETSVAEFS
DGKVRLFTITPEAVGLRRAALADITGGSPAENAQALRRLLAGETGAYRDIVALNAAAAFLVADKVETLREGVELAGRVLD
EGRAQAALERLVEITAP

Sequences:

>Translated_337_residues
MSDAFKPLLSRLADGATLSDDDADAFFSACLRGEPTPAQVGAALTAMRMRGETLGEIAACARAMRRAAIHLEPPFPTIDV
CGTGGDGLHTLNISTAVGFVAAGGGLKVAKHGNRAMSSKSGTADVLGELGVNIAAPPEKQLQALDEAGICFLFAPAHHSA
MRHVSPIRAELGFRTIFNLLGPLTNPAGAQRQVVGVFAERWVKPLAQALGMLGSEKAWVVHGAGLDELTTTGETSVAEFS
DGKVRLFTITPEAVGLRRAALADITGGSPAENAQALRRLLAGETGAYRDIVALNAAAAFLVADKVETLREGVELAGRVLD
EGRAQAALERLVEITAP
>Mature_336_residues
SDAFKPLLSRLADGATLSDDDADAFFSACLRGEPTPAQVGAALTAMRMRGETLGEIAACARAMRRAAIHLEPPFPTIDVC
GTGGDGLHTLNISTAVGFVAAGGGLKVAKHGNRAMSSKSGTADVLGELGVNIAAPPEKQLQALDEAGICFLFAPAHHSAM
RHVSPIRAELGFRTIFNLLGPLTNPAGAQRQVVGVFAERWVKPLAQALGMLGSEKAWVVHGAGLDELTTTGETSVAEFSD
GKVRLFTITPEAVGLRRAALADITGGSPAENAQALRRLLAGETGAYRDIVALNAAAAFLVADKVETLREGVELAGRVLDE
GRAQAALERLVEITAP

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=283, Percent_Identity=45.583038869258, Blast_Score=243, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6320561, Length=362, Percent_Identity=29.8342541436464, Blast_Score=152, Evalue=7e-38,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_PHEZH (B4RBX4)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002130600.1
- GeneID:   6791273
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c1760
- HOGENOM:   HBG559996
- OMA:   ATPSQMG
- ProtClustDB:   PRK00188
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35020; Mature: 34889

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDAFKPLLSRLADGATLSDDDADAFFSACLRGEPTPAQVGAALTAMRMRGETLGEIAAC
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
ARAMRRAAIHLEPPFPTIDVCGTGGDGLHTLNISTAVGFVAAGGGLKVAKHGNRAMSSKS
HHHHHHHEEEECCCCCEEEEECCCCCCEEEEEHHHHHHHHCCCCCEEEEECCCHHHCCCC
GTADVLGELGVNIAAPPEKQLQALDEAGICFLFAPAHHSAMRHVSPIRAELGFRTIFNLL
CHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
GPLTNPAGAQRQVVGVFAERWVKPLAQALGMLGSEKAWVVHGAGLDELTTTGETSVAEFS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHCCCCCCCCEECC
DGKVRLFTITPEAVGLRRAALADITGGSPAENAQALRRLLAGETGAYRDIVALNAAAAFL
CCCEEEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VADKVETLREGVELAGRVLDEGRAQAALERLVEITAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDAFKPLLSRLADGATLSDDDADAFFSACLRGEPTPAQVGAALTAMRMRGETLGEIAAC
CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
ARAMRRAAIHLEPPFPTIDVCGTGGDGLHTLNISTAVGFVAAGGGLKVAKHGNRAMSSKS
HHHHHHHEEEECCCCCEEEEECCCCCCEEEEEHHHHHHHHCCCCCEEEEECCCHHHCCCC
GTADVLGELGVNIAAPPEKQLQALDEAGICFLFAPAHHSAMRHVSPIRAELGFRTIFNLL
CHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
GPLTNPAGAQRQVVGVFAERWVKPLAQALGMLGSEKAWVVHGAGLDELTTTGETSVAEFS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHCCCCCCCCEECC
DGKVRLFTITPEAVGLRRAALADITGGSPAENAQALRRLLAGETGAYRDIVALNAAAAFL
CCCEEEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VADKVETLREGVELAGRVLDEGRAQAALERLVEITAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA