Click here to switch to the map view.

The map label for this gene is csd [H]

Identifier: 197105180

GI number: 197105180

Start: 1924253

End: 1925467

Strand: Reverse

Name: csd [H]

Synonym: PHZ_c1717

Alternate gene names: 197105180

Gene position: 1925467-1924253 (Counterclockwise)

Preceding gene: 197105181

Following gene: 197105179

Centisome position: 48.18

GC content: 70.62

Gene sequence:

>1215_bases
ATGGCCTTCGACGCCGAACAGGTCCGCGCCGAGTTCCCGATCCTGCAGCGGCAGGTGCATGGCAAGCCGCTGGTCTATCT
CGATAGCGCCGCCTCGGCCCAGAAGCCTCGGGCGGTGATCGAGGCCATGACGCGGGCGATGGAGCACTCCTACGCCAACG
TCCACCGCGGCCTGCACACCCTGGCCAACGAGACGACCGACGCCTATGAGGCCGCCCGGCGCAAGGCGGCCGCGTTCATC
GGCGCCGCCGAGGGCGAGATCGTCTTCACCAAGGGCGGCACCGAGGCGGTGAACCTGGTGGCCTCGGGCCTGGCCGCGCG
GCTGCAGCCGGGCGACGAGATCGTGCTCTCCGAGATGGAGCACCACGCCAACATCGTCCCCTGGCACTTCCTGCGCGACC
GCTGCGGCGCGGTGCTGAAGTGGGTCCCGGTGCTGGACGACGGCTCGCTCGACCTCGCGGCCTACCAGGGCCTGCTGGGC
CCCCGGACCCGGGTGGTTGCGCTCTCCCACATGTCCAATGTGCTGGGGACCATCAACCCGGCCAAGGACCTGGCGCGCAT
GGCGCACGAGGCCGGCGCCCTGGTGCTGTTCGACGGCTGCCAGGCCATCGTCCACAAGCCGGTGGACGTGAAGGACATCG
ACGCCGACTTCTACGTCTTCTCGGGCCACAAGCTGTACGGCCCCACGGGCATCGGCGTCCTCTACGGCAAGGCCGAGCTC
CTGGCGCAGCTTCCGCCCTACCAGGGCGGCGGCGAGATGATCGGCACGGTCACGCTGGACGAGATCACCTACGCCGACCC
GCCGCACCGCTTCGAAGCCGGCACGCCGCCGATCCTGGAGGCCATCGGCCTGGGCGCGGCGATCGACTGGCTCTCGGCCC
AGGACCGGATCGCCATCGCCGAGCACGAGCACCGCCTGTACCAGCGGGTCCGCGAACGCCTGGCCGGCGCCAACTGGCTG
AAGGTGATCGGCGAGGCGCCGGGGAAGGGCGCCGTCCTCTCGTTCACCATGGAGGGCGCGCACGCCCACGACGTGGCCCA
GATCCTCGATCGCTACGGGGTGGCGGTGCGGGCCGGGACCCACTGCGCCGAGCCGCTCATGCGGCGTTTCGGGGTGACGT
CGAGCGCCCGGGCCTCCTTCGCCCTATATAACACCGAGGCCGAGGCGGACGCGTTCGTCGACGCCCTCACCAAGACGCAA
GCCTTCTTCGCCTAG

Upstream 100 bases:

>100_bases
TGACGGAGGCCTTTGTGGGCGAGGTGGTCGACCGGGTGGCGTTTGCGCCCGCCCGCGATGTCGCCGCCGCGTGGGTCGCC
GCGCGTCTGAGGGGCGCCTG

Downstream 100 bases:

>100_bases
AGTACGGACATGGATGACGGCGCTTCCATCGAAACCACGGCCACGACGCCGCTCTCCCAGGCGGAGCTCGACCGGCTGAC
GGACCAGCTGATCGAGAAGC

Product: aminotransferase, class V

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MAFDAEQVRAEFPILQRQVHGKPLVYLDSAASAQKPRAVIEAMTRAMEHSYANVHRGLHTLANETTDAYEAARRKAAAFI
GAAEGEIVFTKGGTEAVNLVASGLAARLQPGDEIVLSEMEHHANIVPWHFLRDRCGAVLKWVPVLDDGSLDLAAYQGLLG
PRTRVVALSHMSNVLGTINPAKDLARMAHEAGALVLFDGCQAIVHKPVDVKDIDADFYVFSGHKLYGPTGIGVLYGKAEL
LAQLPPYQGGGEMIGTVTLDEITYADPPHRFEAGTPPILEAIGLGAAIDWLSAQDRIAIAEHEHRLYQRVRERLAGANWL
KVIGEAPGKGAVLSFTMEGAHAHDVAQILDRYGVAVRAGTHCAEPLMRRFGVTSSARASFALYNTEAEADAFVDALTKTQ
AFFA

Sequences:

>Translated_404_residues
MAFDAEQVRAEFPILQRQVHGKPLVYLDSAASAQKPRAVIEAMTRAMEHSYANVHRGLHTLANETTDAYEAARRKAAAFI
GAAEGEIVFTKGGTEAVNLVASGLAARLQPGDEIVLSEMEHHANIVPWHFLRDRCGAVLKWVPVLDDGSLDLAAYQGLLG
PRTRVVALSHMSNVLGTINPAKDLARMAHEAGALVLFDGCQAIVHKPVDVKDIDADFYVFSGHKLYGPTGIGVLYGKAEL
LAQLPPYQGGGEMIGTVTLDEITYADPPHRFEAGTPPILEAIGLGAAIDWLSAQDRIAIAEHEHRLYQRVRERLAGANWL
KVIGEAPGKGAVLSFTMEGAHAHDVAQILDRYGVAVRAGTHCAEPLMRRFGVTSSARASFALYNTEAEADAFVDALTKTQ
AFFA
>Mature_403_residues
AFDAEQVRAEFPILQRQVHGKPLVYLDSAASAQKPRAVIEAMTRAMEHSYANVHRGLHTLANETTDAYEAARRKAAAFIG
AAEGEIVFTKGGTEAVNLVASGLAARLQPGDEIVLSEMEHHANIVPWHFLRDRCGAVLKWVPVLDDGSLDLAAYQGLLGP
RTRVVALSHMSNVLGTINPAKDLARMAHEAGALVLFDGCQAIVHKPVDVKDIDADFYVFSGHKLYGPTGIGVLYGKAELL
AQLPPYQGGGEMIGTVTLDEITYADPPHRFEAGTPPILEAIGLGAAIDWLSAQDRIAIAEHEHRLYQRVRERLAGANWLK
VIGEAPGKGAVLSFTMEGAHAHDVAQILDRYGVAVRAGTHCAEPLMRRFGVTSSARASFALYNTEAEADAFVDALTKTQA
FFA

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=394, Percent_Identity=26.3959390862944, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI156713448, Length=426, Percent_Identity=26.056338028169, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1787970, Length=401, Percent_Identity=49.3765586034913, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1789175, Length=408, Percent_Identity=44.6078431372549, Blast_Score=315, Evalue=4e-87,
Organism=Escherichia coli, GI48994898, Length=397, Percent_Identity=26.7002518891688, Blast_Score=112, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI25143064, Length=229, Percent_Identity=28.82096069869, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI193211090, Length=377, Percent_Identity=25.1989389920424, Blast_Score=94, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319831, Length=393, Percent_Identity=24.6819338422392, Blast_Score=105, Evalue=9e-24,
Organism=Drosophila melanogaster, GI20129463, Length=409, Percent_Identity=28.1173594132029, Blast_Score=136, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 43590; Mature: 43459

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFDAEQVRAEFPILQRQVHGKPLVYLDSAASAQKPRAVIEAMTRAMEHSYANVHRGLHT
CCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LANETTDAYEAARRKAAAFIGAAEGEIVFTKGGTEAVNLVASGLAARLQPGDEIVLSEME
HHCCCHHHHHHHHHHHHHHEECCCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
HHANIVPWHFLRDRCGAVLKWVPVLDDGSLDLAAYQGLLGPRTRVVALSHMSNVLGTINP
HCCCCCCHHHHHHHHHHHEEEEEEECCCCCHHHHHHCCCCCCHHEEHHHHHHHHHHCCCH
AKDLARMAHEAGALVLFDGCQAIVHKPVDVKDIDADFYVFSGHKLYGPTGIGVLYGKAEL
HHHHHHHHHHCCCEEEEECCHHHHCCCCCCEECCCCEEEEECCEEECCCCCEEEECHHHH
LAQLPPYQGGGEMIGTVTLDEITYADPPHRFEAGTPPILEAIGLGAAIDWLSAQDRIAIA
HHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHCCCCCEEHH
EHEHRLYQRVRERLAGANWLKVIGEAPGKGAVLSFTMEGAHAHDVAQILDRYGVAVRAGT
HHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEECCC
HCAEPLMRRFGVTSSARASFALYNTEAEADAFVDALTKTQAFFA
HHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AFDAEQVRAEFPILQRQVHGKPLVYLDSAASAQKPRAVIEAMTRAMEHSYANVHRGLHT
CCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LANETTDAYEAARRKAAAFIGAAEGEIVFTKGGTEAVNLVASGLAARLQPGDEIVLSEME
HHCCCHHHHHHHHHHHHHHEECCCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
HHANIVPWHFLRDRCGAVLKWVPVLDDGSLDLAAYQGLLGPRTRVVALSHMSNVLGTINP
HCCCCCCHHHHHHHHHHHEEEEEEECCCCCHHHHHHCCCCCCHHEEHHHHHHHHHHCCCH
AKDLARMAHEAGALVLFDGCQAIVHKPVDVKDIDADFYVFSGHKLYGPTGIGVLYGKAEL
HHHHHHHHHHCCCEEEEECCHHHHCCCCCCEECCCCEEEEECCEEECCCCCEEEECHHHH
LAQLPPYQGGGEMIGTVTLDEITYADPPHRFEAGTPPILEAIGLGAAIDWLSAQDRIAIA
HHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHCCCCCEEHH
EHEHRLYQRVRERLAGANWLKVIGEAPGKGAVLSFTMEGAHAHDVAQILDRYGVAVRAGT
HHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEECCC
HCAEPLMRRFGVTSSARASFALYNTEAEADAFVDALTKTQAFFA
HHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]