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The map label for this gene is lptD [H]

Identifier: 197105170

GI number: 197105170

Start: 1913837

End: 1916185

Strand: Direct

Name: lptD [H]

Synonym: PHZ_c1707

Alternate gene names: 197105170

Gene position: 1913837-1916185 (Clockwise)

Preceding gene: 197105169

Following gene: 197105171

Centisome position: 47.89

GC content: 69.09

Gene sequence:

>2349_bases
TTGATGAGTCCGCGTCGGCGTACGCCCCGACACGCAGGCAAGCGCGCCCTAATGGCCGGCGCTGCGCTCGCGCTCCTGTG
GTCCGCCGCGGCCCACGCCCAGGCGCCCGAGTCCGCCGCCCCGGCCCAGGCCCAGCCGGGTCCTGACGGCCTGCTGCCCG
ACGAGATGTACATCGAGGCGGACGAGGTCATCCGGGAGGACGAGACGGGCCGCACCACCGCCCAGGGCAACCTCGAGATC
CGCTACAACGACCGCACCCTGCGCGCCGACCGCCTCGTCTACGAAGAGGACACGGGCGTCATCCGCGCGTTCGGCAACAT
CGTCATCGTCAACGCCGACGGCTCGACCGAATACGCTGACGAGGCCGTGCTGGACGACGACATGCGCGCGGGCGTCGTCC
TGGGCTTCGCGGCCCGCCTGTCCGAGAACGTCAAGATCGCCGCCGCCAGCGCCGCGCGGCGCAACGACAACATCCAGGAG
CTGAACCGGGCCATCTACACGCCGTGCGAGATCTGCGCGGCGGACGGCACGCCCAAGAAGCCCACCTGGTCGATCGCCGC
CGACAAGGTGGTCCAGGACAAGAAGCGGCGGATCGTCTACTACCGCCACGCTCGCTTCCGCCTGTTCGGCGCCTCGGTGC
TCTACCTGCCGCTGTTCTGGCACGCCGACCCGCAGGCCGGCCGCTCGTCGGGGTTCCTGACCCCCAAGGCCTCGTTCTCG
GACCGTCGCGGCTTCTCGTACGAGCAGCCCTATTACCAGGTGATCTCGCCCTCGGCGGACATGATCATCAGTCCGCAGAT
CAACACCAAGATCGCGCCGTTCCTGAACGGCCAGGTGCGCAAGCGCTTCTACTCGGGCGATGTCGACGTGCGGTTCGGCT
ACACCCACGCCCGCGACTTCGACGGCCAAGGCAACGAGATCGTCGGCACCCGCACCGACCGCAGCTACATCCTCGGCCGC
GGCAGCTTCGAGATCGATGAGAAGTGGCGGTGGGGCTTCACGGCCGAACGGACCTCGGACGACCTGATCTTCGACAAGTA
CGAGGTGGGCCGGGTCTACGTCAGCCGCGGCCCCTACGTCGCCGACGACCGGCGGCTGATCAGCCAGGTCTACGCCATCC
GCCAGGACGAACGATCGTACTTCTCGGCGGCGGCCATGACGATCCAGGGGCTGCGCCCAGAGTTCGCCCCGGGCGACCAG
GTGGCCCGGGGCGAGAACGACAGGGTGTTCCCGGTCATCGGACCGCTGGTGGAGGGGCACTATGAGCTGCCCGGCATGGT
CGCCGGCGGGCGCCTGCGGGTGCACACCAGCGCCGTCGTGCTCAGCCGCGAGCAGTCCCAGTTCTTCCCCGAGCAGCGCC
TGCCCGGGATCGACAGCGCCCGCCTGACCGGCGAGGTGGACTGGCGGCGCACCTTCACCTCGGCGGCCGGCGTGCGCCTC
TCGCCGTTCGTGAACCTGCGCGCCGACGCCTACCGCATCCAGGACATCCTGACCGGCGTCGGCTCGGCCACCCGCAAGGA
CGAGCTCGGCCGGGGCCTGGCCACCGTCGGCCTCGACCTGACCTATCCTTTCTTCAAGCGCTCGGGCGACGCCACCATCG
TCGTGGAGCCTGTGGTGCAGCTGGCCGCCTCTCCGGACGCCAAGCAGGTGGTGATCGGCGAGGATCCGGTCACGGGCGAG
CCGATCTACCTGAACGAGGACAGCGTCGCCTTCGAGTTCGACGAGACGACCCTCTTCCGGCCCAACAAGTTCCCCGGCTA
CGACCTCTACGAGGACGGGGTCCGCCTGAACGTCGCCGGCCGCGCCTCGGTGCTCTGGGACGATGGGCGGCGGGCCAACC
TGCTGGTCGGCCGGGCCTTCCGCACGGAGGAGAACCGGGTGTTCTCCGAGCGCTCGGGCCTGCGCAGCGAGTCCTCGGAC
TGGATCGTGGCCGCCGACGCCCAGCCGGTCCGCGGGCTGTCGATGTTCGCCCGCGCCCGCCTCGACAGCGACGACTTCGA
CATCCACCGCCTGGAGGCCGGCGCCAACGTCTACAACCGCTACGGCAACGGCTTCGTCCGCTACCTCACCGACGACTTCG
ACATCACCGGCCGCAAGCGCGAGAACCTGGACCTCGGCGGCGAGGTCTACGTCGGCAAGAACTGGGGCGTCAGCTTCTAC
GGCAACCGCGACCTCAACGAGGACGCATGGGTGATCCGGGACCTGGGCGTCTTCTACCGGGACGACTGCATCCGGGTGGA
TGTGGTCTATCGCCGCGAAGACACGATCATCGGCCGTCTGCTACCCAGTGAGTCCGTCTCGGTGCGCCTAACGCTCGCCA
CATTGGGCGGAACATCTGATGGCAGGTAG

Upstream 100 bases:

>100_bases
CTTTGCTACACCGAAGACGGTTGAATCGTTGGCGCGCCGGGATATGCATCGCCGCTGGAGCCAGCTTGAGCGCGCGTCGA
CGCGAGAGGGGATCGGAAGC

Downstream 100 bases:

>100_bases
AATGCCAGGCGGACTGCGCCCTACGAAGGAAACGATCTCGTCCATGAAGTCTCTTGTCACGGGCCCTGCGGCGCGGAGCG
CGGCGATCGCCTGCGCCCTG

Product: organic solvent tolerance protein OstA

Products: NA

Alternate protein names: Organic solvent tolerance protein [H]

Number of amino acids: Translated: 782; Mature: 782

Protein sequence:

>782_residues
MMSPRRRTPRHAGKRALMAGAALALLWSAAAHAQAPESAAPAQAQPGPDGLLPDEMYIEADEVIREDETGRTTAQGNLEI
RYNDRTLRADRLVYEEDTGVIRAFGNIVIVNADGSTEYADEAVLDDDMRAGVVLGFAARLSENVKIAAASAARRNDNIQE
LNRAIYTPCEICAADGTPKKPTWSIAADKVVQDKKRRIVYYRHARFRLFGASVLYLPLFWHADPQAGRSSGFLTPKASFS
DRRGFSYEQPYYQVISPSADMIISPQINTKIAPFLNGQVRKRFYSGDVDVRFGYTHARDFDGQGNEIVGTRTDRSYILGR
GSFEIDEKWRWGFTAERTSDDLIFDKYEVGRVYVSRGPYVADDRRLISQVYAIRQDERSYFSAAAMTIQGLRPEFAPGDQ
VARGENDRVFPVIGPLVEGHYELPGMVAGGRLRVHTSAVVLSREQSQFFPEQRLPGIDSARLTGEVDWRRTFTSAAGVRL
SPFVNLRADAYRIQDILTGVGSATRKDELGRGLATVGLDLTYPFFKRSGDATIVVEPVVQLAASPDAKQVVIGEDPVTGE
PIYLNEDSVAFEFDETTLFRPNKFPGYDLYEDGVRLNVAGRASVLWDDGRRANLLVGRAFRTEENRVFSERSGLRSESSD
WIVAADAQPVRGLSMFARARLDSDDFDIHRLEAGANVYNRYGNGFVRYLTDDFDITGRKRENLDLGGEVYVGKNWGVSFY
GNRDLNEDAWVIRDLGVFYRDDCIRVDVVYRREDTIIGRLLPSESVSVRLTLATLGGTSDGR

Sequences:

>Translated_782_residues
MMSPRRRTPRHAGKRALMAGAALALLWSAAAHAQAPESAAPAQAQPGPDGLLPDEMYIEADEVIREDETGRTTAQGNLEI
RYNDRTLRADRLVYEEDTGVIRAFGNIVIVNADGSTEYADEAVLDDDMRAGVVLGFAARLSENVKIAAASAARRNDNIQE
LNRAIYTPCEICAADGTPKKPTWSIAADKVVQDKKRRIVYYRHARFRLFGASVLYLPLFWHADPQAGRSSGFLTPKASFS
DRRGFSYEQPYYQVISPSADMIISPQINTKIAPFLNGQVRKRFYSGDVDVRFGYTHARDFDGQGNEIVGTRTDRSYILGR
GSFEIDEKWRWGFTAERTSDDLIFDKYEVGRVYVSRGPYVADDRRLISQVYAIRQDERSYFSAAAMTIQGLRPEFAPGDQ
VARGENDRVFPVIGPLVEGHYELPGMVAGGRLRVHTSAVVLSREQSQFFPEQRLPGIDSARLTGEVDWRRTFTSAAGVRL
SPFVNLRADAYRIQDILTGVGSATRKDELGRGLATVGLDLTYPFFKRSGDATIVVEPVVQLAASPDAKQVVIGEDPVTGE
PIYLNEDSVAFEFDETTLFRPNKFPGYDLYEDGVRLNVAGRASVLWDDGRRANLLVGRAFRTEENRVFSERSGLRSESSD
WIVAADAQPVRGLSMFARARLDSDDFDIHRLEAGANVYNRYGNGFVRYLTDDFDITGRKRENLDLGGEVYVGKNWGVSFY
GNRDLNEDAWVIRDLGVFYRDDCIRVDVVYRREDTIIGRLLPSESVSVRLTLATLGGTSDGR
>Mature_782_residues
MMSPRRRTPRHAGKRALMAGAALALLWSAAAHAQAPESAAPAQAQPGPDGLLPDEMYIEADEVIREDETGRTTAQGNLEI
RYNDRTLRADRLVYEEDTGVIRAFGNIVIVNADGSTEYADEAVLDDDMRAGVVLGFAARLSENVKIAAASAARRNDNIQE
LNRAIYTPCEICAADGTPKKPTWSIAADKVVQDKKRRIVYYRHARFRLFGASVLYLPLFWHADPQAGRSSGFLTPKASFS
DRRGFSYEQPYYQVISPSADMIISPQINTKIAPFLNGQVRKRFYSGDVDVRFGYTHARDFDGQGNEIVGTRTDRSYILGR
GSFEIDEKWRWGFTAERTSDDLIFDKYEVGRVYVSRGPYVADDRRLISQVYAIRQDERSYFSAAAMTIQGLRPEFAPGDQ
VARGENDRVFPVIGPLVEGHYELPGMVAGGRLRVHTSAVVLSREQSQFFPEQRLPGIDSARLTGEVDWRRTFTSAAGVRL
SPFVNLRADAYRIQDILTGVGSATRKDELGRGLATVGLDLTYPFFKRSGDATIVVEPVVQLAASPDAKQVVIGEDPVTGE
PIYLNEDSVAFEFDETTLFRPNKFPGYDLYEDGVRLNVAGRASVLWDDGRRANLLVGRAFRTEENRVFSERSGLRSESSD
WIVAADAQPVRGLSMFARARLDSDDFDIHRLEAGANVYNRYGNGFVRYLTDDFDITGRKRENLDLGGEVYVGKNWGVSFY
GNRDLNEDAWVIRDLGVFYRDDCIRVDVVYRREDTIIGRLLPSESVSVRLTLATLGGTSDGR

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis [H]

COG id: COG1452

COG function: function code M; Organic solvent tolerance protein OstA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family [H]

Homologues:

None

Paralogues:

None

Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020889
- InterPro:   IPR005653
- InterPro:   IPR007543 [H]

Pfam domain/function: PF03968 OstA; PF04453 OstA_C [H]

EC number: NA

Molecular weight: Translated: 87302; Mature: 87302

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSPRRRTPRHAGKRALMAGAALALLWSAAAHAQAPESAAPAQAQPGPDGLLPDEMYIEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEH
DEVIREDETGRTTAQGNLEIRYNDRTLRADRLVYEEDTGVIRAFGNIVIVNADGSTEYAD
HHHHCCCCCCCEEECCEEEEEECCCEEEECEEEEECCCCEEEEECCEEEEECCCCCCCCC
EAVLDDDMRAGVVLGFAARLSENVKIAAASAARRNDNIQELNRAIYTPCEICAADGTPKK
HHHCCCCCCCCEEEEEHHHCCCCEEEEEECHHHCCCCHHHHHHHHCCCHHEEECCCCCCC
PTWSIAADKVVQDKKRRIVYYRHARFRLFGASVLYLPLFWHADPQAGRSSGFLTPKASFS
CEEEHHHHHHHHHCCCEEEEEEEEEEEEECCEEEEEEEEECCCCCCCCCCCCCCCCCCCC
DRRGFSYEQPYYQVISPSADMIISPQINTKIAPFLNGQVRKRFYSGDVDVRFGYTHARDF
CCCCCCCCCCCCEEECCCCCEEECCCCCCEECCCCCCHHHHHEECCCEEEEECCCCCCCC
DGQGNEIVGTRTDRSYILGRGSFEIDEKWRWGFTAERTSDDLIFDKYEVGRVYVSRGPYV
CCCCCEEEEECCCCEEEEECCCEEECCCEECCEECCCCCCCEEEEEEEECEEEEECCCEE
ADDRRLISQVYAIRQDERSYFSAAAMTIQGLRPEFAPGDQVARGENDRVFPVIGPLVEGH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECHHHCCC
YELPGMVAGGRLRVHTSAVVLSREQSQFFPEQRLPGIDSARLTGEVDWRRTFTSAAGVRL
CCCCCEEECCEEEEEEEEEEEECCHHHCCCHHCCCCCCCCEEEECCHHHHHHHHHCCEEE
SPFVNLRADAYRIQDILTGVGSATRKDELGRGLATVGLDLTYPFFKRSGDATIVVEPVVQ
CCEEECCCHHHHHHHHHHHCCCCCCHHHHCCCEEEEEEEEECHHHHCCCCCEEEEEHHHH
LAASPDAKQVVIGEDPVTGEPIYLNEDSVAFEFDETTLFRPNKFPGYDLYEDGVRLNVAG
HHCCCCCCEEEECCCCCCCCCEEECCCCEEEEECCEEEECCCCCCCCCEECCCEEEEECC
RASVLWDDGRRANLLVGRAFRTEENRVFSERSGLRSESSDWIVAADAQPVRGLSMFARAR
CEEEEECCCCEEEEEEEEEEECCCHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHH
LDSDDFDIHRLEAGANVYNRYGNGFVRYLTDDFDITGRKRENLDLGGEVYVGKNWGVSFY
CCCCCCCEEEEECCCHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCEEEE
GNRDLNEDAWVIRDLGVFYRDDCIRVDVVYRREDTIIGRLLPSESVSVRLTLATLGGTSD
CCCCCCCCCEEEECCCCEECCCEEEEEEEEECCCCEEEEECCCCCEEEEEEEEEECCCCC
GR
CC
>Mature Secondary Structure
MMSPRRRTPRHAGKRALMAGAALALLWSAAAHAQAPESAAPAQAQPGPDGLLPDEMYIEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEH
DEVIREDETGRTTAQGNLEIRYNDRTLRADRLVYEEDTGVIRAFGNIVIVNADGSTEYAD
HHHHCCCCCCCEEECCEEEEEECCCEEEECEEEEECCCCEEEEECCEEEEECCCCCCCCC
EAVLDDDMRAGVVLGFAARLSENVKIAAASAARRNDNIQELNRAIYTPCEICAADGTPKK
HHHCCCCCCCCEEEEEHHHCCCCEEEEEECHHHCCCCHHHHHHHHCCCHHEEECCCCCCC
PTWSIAADKVVQDKKRRIVYYRHARFRLFGASVLYLPLFWHADPQAGRSSGFLTPKASFS
CEEEHHHHHHHHHCCCEEEEEEEEEEEEECCEEEEEEEEECCCCCCCCCCCCCCCCCCCC
DRRGFSYEQPYYQVISPSADMIISPQINTKIAPFLNGQVRKRFYSGDVDVRFGYTHARDF
CCCCCCCCCCCCEEECCCCCEEECCCCCCEECCCCCCHHHHHEECCCEEEEECCCCCCCC
DGQGNEIVGTRTDRSYILGRGSFEIDEKWRWGFTAERTSDDLIFDKYEVGRVYVSRGPYV
CCCCCEEEEECCCCEEEEECCCEEECCCEECCEECCCCCCCEEEEEEEECEEEEECCCEE
ADDRRLISQVYAIRQDERSYFSAAAMTIQGLRPEFAPGDQVARGENDRVFPVIGPLVEGH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECHHHCCC
YELPGMVAGGRLRVHTSAVVLSREQSQFFPEQRLPGIDSARLTGEVDWRRTFTSAAGVRL
CCCCCEEECCEEEEEEEEEEEECCHHHCCCHHCCCCCCCCEEEECCHHHHHHHHHCCEEE
SPFVNLRADAYRIQDILTGVGSATRKDELGRGLATVGLDLTYPFFKRSGDATIVVEPVVQ
CCEEECCCHHHHHHHHHHHCCCCCCHHHHCCCEEEEEEEEECHHHHCCCCCEEEEEHHHH
LAASPDAKQVVIGEDPVTGEPIYLNEDSVAFEFDETTLFRPNKFPGYDLYEDGVRLNVAG
HHCCCCCCEEEECCCCCCCCCEEECCCCEEEEECCEEEECCCCCCCCCEECCCEEEEECC
RASVLWDDGRRANLLVGRAFRTEENRVFSERSGLRSESSDWIVAADAQPVRGLSMFARAR
CEEEEECCCCEEEEEEEEEEECCCHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHH
LDSDDFDIHRLEAGANVYNRYGNGFVRYLTDDFDITGRKRENLDLGGEVYVGKNWGVSFY
CCCCCCCEEEEECCCHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCEEEE
GNRDLNEDAWVIRDLGVFYRDDCIRVDVVYRREDTIIGRLLPSESVSVRLTLATLGGTSD
CCCCCCCCCEEEECCCCEECCCEEEEEEEEECCCCEEEEECCCCCEEEEEEEEEECCCCC
GR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]