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The map label for this gene is ribH [H]

Identifier: 197105132

GI number: 197105132

Start: 1874451

End: 1874915

Strand: Reverse

Name: ribH [H]

Synonym: PHZ_c1669

Alternate gene names: 197105132

Gene position: 1874915-1874451 (Counterclockwise)

Preceding gene: 197105133

Following gene: 197105131

Centisome position: 46.92

GC content: 71.4

Gene sequence:

>465_bases
ATGAGCGACCAACCCCTTCGCATCCTGATCGTGGAAGCGCGCTTCTACGACGACCTGGCCGACGCCCTGCTGGAAGGCGC
CGTCGACGCGCTGAAGGCCTATGGCGCGGAGTACGACGTGGTGACCGTGCCGGGCGCGCTGGAGATCCCCGGCGCGATCG
CCCTGGCCGAGGAGGCCGGGCACGGCCCGAGCGGCGTCCGCTACGACGGCTACGTGGCCCTCGGCTGCGTCATCCGCGGC
GAGACCTACCACTTCGAGATCGTCTCCAACGAGAGCGCGCGGGGGATCATGGACCTGACGGTCCACAAGCGCCTGTGCAT
CGGCAACGGGATCCTGACGACCGAGGACGACGAGCAGGCCTGGGCGCGGGCCCGGATCAGCGAAGGCGACAAGGGCGGCG
GCGCGGCCCGCGCGGCCCTGGCGATGGTGGCGCTGAAGCAGCAGCTGACGGCGGGCGGGCGATGA

Upstream 100 bases:

>100_bases
ACCCTGGGCGAGCTCGCGCCGGGCGGCCGGGTCAATCTCGAGATCGACATGCTCGCGAGGTATCTCGCCCGCTGGCGCGA
AACCGCCTAAAGGGGCGGGA

Downstream 100 bases:

>100_bases
GCGCGGCCCGGGCATCCCGATCGGTCGCGCGCCTGGCGGCCGTCCAGGCGCTGTACCAGATGGAGGTCTCCTCCACCGGC
GTGGAGGCGGTCATCCGCGA

Product: riboflavin synthase, beta subunit

Products: NA

Alternate protein names: DMRL synthase 1; Lumazine synthase 1; Riboflavin synthase 1 beta chain [H]

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MSDQPLRILIVEARFYDDLADALLEGAVDALKAYGAEYDVVTVPGALEIPGAIALAEEAGHGPSGVRYDGYVALGCVIRG
ETYHFEIVSNESARGIMDLTVHKRLCIGNGILTTEDDEQAWARARISEGDKGGGAARAALAMVALKQQLTAGGR

Sequences:

>Translated_154_residues
MSDQPLRILIVEARFYDDLADALLEGAVDALKAYGAEYDVVTVPGALEIPGAIALAEEAGHGPSGVRYDGYVALGCVIRG
ETYHFEIVSNESARGIMDLTVHKRLCIGNGILTTEDDEQAWARARISEGDKGGGAARAALAMVALKQQLTAGGR
>Mature_153_residues
SDQPLRILIVEARFYDDLADALLEGAVDALKAYGAEYDVVTVPGALEIPGAIALAEEAGHGPSGVRYDGYVALGCVIRGE
TYHFEIVSNESARGIMDLTVHKRLCIGNGILTTEDDEQAWARARISEGDKGGGAARAALAMVALKQQLTAGGR

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=149, Percent_Identity=40.9395973154362, Blast_Score=95, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324429, Length=127, Percent_Identity=32.2834645669291, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16260; Mature: 16128

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQPLRILIVEARFYDDLADALLEGAVDALKAYGAEYDVVTVPGALEIPGAIALAEEAG
CCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCEEEEHHHCC
HGPSGVRYDGYVALGCVIRGETYHFEIVSNESARGIMDLTVHKRLCIGNGILTTEDDEQA
CCCCCCEECCEEEEEEEEECCEEEEEEECCCCCCCEEEHHHHHHEEECCCEEECCCCHHH
WARARISEGDKGGGAARAALAMVALKQQLTAGGR
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDQPLRILIVEARFYDDLADALLEGAVDALKAYGAEYDVVTVPGALEIPGAIALAEEAG
CCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCEEEEHHHCC
HGPSGVRYDGYVALGCVIRGETYHFEIVSNESARGIMDLTVHKRLCIGNGILTTEDDEQA
CCCCCCEECCEEEEEEEEECCEEEEEEECCCCCCCEEEHHHHHHEEECCCEEECCCCHHH
WARARISEGDKGGGAARAALAMVALKQQLTAGGR
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]