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The map label for this gene is cfa [H]

Identifier: 197105090

GI number: 197105090

Start: 1834621

End: 1835832

Strand: Direct

Name: cfa [H]

Synonym: PHZ_c1627

Alternate gene names: 197105090

Gene position: 1834621-1835832 (Clockwise)

Preceding gene: 197105084

Following gene: 197105091

Centisome position: 45.91

GC content: 69.14

Gene sequence:

>1212_bases
ATGGGCCTGGATCACAAGATCGCGGAGCTCGCCGGCGCGCCAGCGGCCTTCAGAGCCGCCGCCAGGATCATCGCGCGCAA
CTGGCAGGCGGGCGTCCTCACCTTCGTGCTGCCGGACGGGCGCGAGTTCCGGCTGCAGGGCGATGCGCCCGGCCGCGACG
GCCGCCTGGTGGTCCGCGACTATCGCTTCATGAAACGGGTGCTGGCCTCGGGCGACATCGGCTTCGCCGAAGGCTACATG
GCCGGCGAGTGGGACACGCCCGACCTTTCGGCGCTGCTGGAGGTCCTGGCGCTGAACTTCAACAACATCGACCAAGTGGC
CACGGGCAATCCGGTGATGTCCTTCGTCCACTTCGTCGGCCACCTGCTGCGCGGCAACACGCGAGCGGGCTCGCGGCGGA
ACATCCACGCCCACTACGACCTCGGGAACGCCTTCTATTCGCGCTGGCTGGACCCCACCATGACCTACTCGTCGGCTCGC
TTCGAGAAGCCCGGCGAGCCGCTGTCCGAGGCCCAGCGGCGCAAGTACCGCACCCTCGCCGAGAGCATGGGGCTGAAGCC
CGACCACCACGTGCTGGAGATCGGCTGCGGCTGGGGCGGCTTCGCCGAGTACGCCGCCCGCGAGGTGGGCGCGAAGGTCA
CCGGCATCACCATTTCCGAGGAGCAGTACAGGTTCGCGAGTCGGCGGATGTTCGAGCAGGGGCTGAACGAGCGGGCCGAG
ATCCGGCTGGTGGACTACCGCGACGTCGAGGGCCGGTTCGACCGGGTCGCCTCCATCGAGATGTTCGAGGCGGTGGGCGA
GCGCTACTGGCCCACCTACTTCGGGAAGATCCGCGAGAGCCTCGCCCCCGGCGGCCGGGCCGGCCTGCAGATCATCACCA
TCCGGGACGAACTGTTCGACCACTACCGGCGGCGGGCCGACTTCATCCAGAAGTACATCTTCCCGGGCGGCATGCTGCCT
TCGGAGGCGCGGCTGAAGGCCGAGACCGAGAAGGCGGGGCTCTCCTGGGCCGGCGTCTCGCGCTTCGGCCAGAACTACGC
CGACACCCTGGCCGAGTGGGCCCGGCGCTTCGAGGGGGCCTGGGACGACATCCGCCGGCTGGGCTTCGACGAGCGGTTCC
GCAAGCTCTGGCGCTTCTATCTCAGCTACTGCGAGGCCGGCTTCCGCACCGCGCGGACCGACGTCGTTCAGCTCAGCTTG
GCGCGGACTTAG

Upstream 100 bases:

>100_bases
CGGCATCCGCCGGCCAGCCGCGGCCGTAGTTGAGCTCGCCGGCGATTCGCACGCCGGCGAAGATCGGTGTTATCGTTGTC
TGGCTTAGGGGGAAGCGAGC

Downstream 100 bases:

>100_bases
AAATCCGCCCCTGTCGCAACCGGCCCGGCTTGCCTAATTAGCGACCATGCAAGTCGCCCAAAGCGTCCTCGACCTGATCG
GGAACACGCCCCTCCTCCGC

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MGLDHKIAELAGAPAAFRAAARIIARNWQAGVLTFVLPDGREFRLQGDAPGRDGRLVVRDYRFMKRVLASGDIGFAEGYM
AGEWDTPDLSALLEVLALNFNNIDQVATGNPVMSFVHFVGHLLRGNTRAGSRRNIHAHYDLGNAFYSRWLDPTMTYSSAR
FEKPGEPLSEAQRRKYRTLAESMGLKPDHHVLEIGCGWGGFAEYAAREVGAKVTGITISEEQYRFASRRMFEQGLNERAE
IRLVDYRDVEGRFDRVASIEMFEAVGERYWPTYFGKIRESLAPGGRAGLQIITIRDELFDHYRRRADFIQKYIFPGGMLP
SEARLKAETEKAGLSWAGVSRFGQNYADTLAEWARRFEGAWDDIRRLGFDERFRKLWRFYLSYCEAGFRTARTDVVQLSL
ART

Sequences:

>Translated_403_residues
MGLDHKIAELAGAPAAFRAAARIIARNWQAGVLTFVLPDGREFRLQGDAPGRDGRLVVRDYRFMKRVLASGDIGFAEGYM
AGEWDTPDLSALLEVLALNFNNIDQVATGNPVMSFVHFVGHLLRGNTRAGSRRNIHAHYDLGNAFYSRWLDPTMTYSSAR
FEKPGEPLSEAQRRKYRTLAESMGLKPDHHVLEIGCGWGGFAEYAAREVGAKVTGITISEEQYRFASRRMFEQGLNERAE
IRLVDYRDVEGRFDRVASIEMFEAVGERYWPTYFGKIRESLAPGGRAGLQIITIRDELFDHYRRRADFIQKYIFPGGMLP
SEARLKAETEKAGLSWAGVSRFGQNYADTLAEWARRFEGAWDDIRRLGFDERFRKLWRFYLSYCEAGFRTARTDVVQLSL
ART
>Mature_402_residues
GLDHKIAELAGAPAAFRAAARIIARNWQAGVLTFVLPDGREFRLQGDAPGRDGRLVVRDYRFMKRVLASGDIGFAEGYMA
GEWDTPDLSALLEVLALNFNNIDQVATGNPVMSFVHFVGHLLRGNTRAGSRRNIHAHYDLGNAFYSRWLDPTMTYSSARF
EKPGEPLSEAQRRKYRTLAESMGLKPDHHVLEIGCGWGGFAEYAAREVGAKVTGITISEEQYRFASRRMFEQGLNERAEI
RLVDYRDVEGRFDRVASIEMFEAVGERYWPTYFGKIRESLAPGGRAGLQIITIRDELFDHYRRRADFIQKYIFPGGMLPS
EARLKAETEKAGLSWAGVSRFGQNYADTLAEWARRFEGAWDDIRRLGFDERFRKLWRFYLSYCEAGFRTARTDVVQLSLA
RT

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=382, Percent_Identity=34.2931937172775, Blast_Score=193, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI133904226, Length=376, Percent_Identity=38.563829787234, Blast_Score=239, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 45901; Mature: 45769

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLDHKIAELAGAPAAFRAAARIIARNWQAGVLTFVLPDGREFRLQGDAPGRDGRLVVRD
CCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCCEEHHH
YRFMKRVLASGDIGFAEGYMAGEWDTPDLSALLEVLALNFNNIDQVATGNPVMSFVHFVG
HHHHHHHHHCCCCCCCCCEECCCCCCCCHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHH
HLLRGNTRAGSRRNIHAHYDLGNAFYSRWLDPTMTYSSARFEKPGEPLSEAQRRKYRTLA
HHHCCCCCCCCCCCEEEEECHHHHHHHHCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHH
ESMGLKPDHHVLEIGCGWGGFAEYAAREVGAKVTGITISEEQYRFASRRMFEQGLNERAE
HHCCCCCCCCEEEEECCCCHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHCCCCCCE
IRLVDYRDVEGRFDRVASIEMFEAVGERYWPTYFGKIRESLAPGGRAGLQIITIRDELFD
EEEEECCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEEEHHHHHH
HYRRRADFIQKYIFPGGMLPSEARLKAETEKAGLSWAGVSRFGQNYADTLAEWARRFEGA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHCCC
WDDIRRLGFDERFRKLWRFYLSYCEAGFRTARTDVVQLSLART
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
>Mature Secondary Structure 
GLDHKIAELAGAPAAFRAAARIIARNWQAGVLTFVLPDGREFRLQGDAPGRDGRLVVRD
CCCHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCCEEHHH
YRFMKRVLASGDIGFAEGYMAGEWDTPDLSALLEVLALNFNNIDQVATGNPVMSFVHFVG
HHHHHHHHHCCCCCCCCCEECCCCCCCCHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHH
HLLRGNTRAGSRRNIHAHYDLGNAFYSRWLDPTMTYSSARFEKPGEPLSEAQRRKYRTLA
HHHCCCCCCCCCCCEEEEECHHHHHHHHCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHH
ESMGLKPDHHVLEIGCGWGGFAEYAAREVGAKVTGITISEEQYRFASRRMFEQGLNERAE
HHCCCCCCCCEEEEECCCCHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHCCCCCCE
IRLVDYRDVEGRFDRVASIEMFEAVGERYWPTYFGKIRESLAPGGRAGLQIITIRDELFD
EEEEECCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEEEHHHHHH
HYRRRADFIQKYIFPGGMLPSEARLKAETEKAGLSWAGVSRFGQNYADTLAEWARRFEGA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHCCC
WDDIRRLGFDERFRKLWRFYLSYCEAGFRTARTDVVQLSLART
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]