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The map label for this gene is recG [H]

Identifier: 197105084

GI number: 197105084

Start: 1826902

End: 1828977

Strand: Direct

Name: recG [H]

Synonym: PHZ_c1621

Alternate gene names: 197105084

Gene position: 1826902-1828977 (Clockwise)

Preceding gene: 197105081

Following gene: 197105090

Centisome position: 45.72

GC content: 73.51

Gene sequence:

>2076_bases
ATGCGGCCGGAGATTCTGTTCCCGCTGTTTGCGCCGATAACCTCCTTGAAGGGGGTGGGCCCGCGCGTGGCCCCGCTGCT
GGAGAAGGTGGCGGGCCCGATCGTGCGCGACGTGTTGTGGCTGAAGCCGCACTCGCTGATCCGCCGCACGCCCGCGGTGC
TGTCGGCCGCCCGCGACGGCGAGACCATGACCTTCGAGGTGGCGATCCACGGCTATCAGGCGCCGCGGACCAAGGCCCAG
CCGTGGCGGGTGCAGGTGACCGACCCCACCGGCTTCATGACCCTGGTGTTCTTCGGCCGCTACGGCGACCAGCTCGCCCA
GCGCCATCCGGTGGGCGCGAGAAGGATCGTCTCGGGCAAGGTCGAGGAGAGCAGCTTCGGCCGGCAGATGGTCCATCCCG
ACTACATCCTGCCGCCCGAGAAGGCCGGCGAGATTCCCGAGCTCGAGGCGGTATATCCGGCGACCGAAGGCCTGCCCGCG
CGCCGGGTGCGCGGCTTCGTGCTCGAGGCGCTGGAGCGCGCGCCCGAGCTGCCGGAATGGCAGGACCCGGCGTTCCTGCG
CCAGGAGCAGTTCCCCGCCTGGCGCGCGGCGATGGAGCGCCTGCACAATCCGCAGAGCGAGGCCGACCTGTCGCTGCTGA
GCCCGCACCGGCGACGGCTGGCCTTCGACGAGCTGCTGGCGCACCAGCTGGCCATGGCGCAGCGCAAGGCGGCGCGCCGG
CGCGAGCCCGCCGCCAGGGTCGCCGCGAGCGAGACGGCCGAGAAGATCCGCGCGGACCTGCCCTTTCGGTTCACCGGAGC
CCAGGAGCGCGCCCTGGCCGAGATCCGCGCCGATCTTTCCGCCGGCGAGCGGATGAGCCGGCTGGTCCAGGGGGACGTCG
GCTCGGGCAAGACGGTGGTGGCGATGTGCGCCATGGCGGACGTGGCGGCCAGCGGCGGCCAGTCGGCCCTGATGGCCCCG
ACCGAAATCCTGGCCCGGCAGCACTACGAGACCATCTCGGGGCCCCTGGCCGCGCATGGCGTGGGAACCGTCCTGCTGAC
CGGCCGCGACAAGGGGGCGGCGCGCCGGGAGAAGCTGGCGGCCCTGGCCTCGGGCGAGGCCAGGGTGGCGGTGGGCACCC
ACGCGCTCTTTCAGGACGAGGTGGCGTTCCAGAAGCTGCAGCTGGTGGTCATCGACGAGCAGCACCGGTTCGGCGTCGCC
GAGCGCCAGCGGCTGCAGGCCAAGGGCGAGGCCACCCACCTGATCGCCATGTCGGCCACGCCGATCCCGCGCACGCTGGA
GCTGACCGTCTACGGCGACCTCGACGTCAGCCGGATCGACGAAAAGCCCCCTGGCCGCACGCCGGTGGCCACCCGCGCCG
CGCCGATGACCCGGGCGCACGAGGTGGAGGCCCGCCTGCGCGAGGCGGTGCAGGGCGGCGCCCAGGCGTTCTGGATCTGC
CCGCTGGTCTCGGAGTCGGAGGCCACCGACCTGGCCGCCGCCGAGCGCCGGGCCGCCGAGCTGACCGAGCGCATCGGCCC
CAGCGTGGGCCTGGTCCACGGCCGCCTGCCGCCCGCCGCCAAGGACGCGGTGATGGCGGAGTTCGCCGAGGGGCGGCTCT
CCGTCCTCGTCGCCACCACGGTGGTCGAGGTGGGCGTCAACGTGCCCAACGCCACCATCATGGTCATCGAGCAGGCCGAG
CGCTTCGGCCTGGCCCAGCTCCACCAGCTCCGGGGCCGGGTCGGGCGCGGACGGCGCGAGAGCGCCTGCGTGCTGCTGTA
CGACCCGCCGCTGTCGGAGACCGCGCAGCAGCGGCTGGACATCCTGCGTCGCACCGACGACGGCTTCGTCATCGCCGAGA
AGGACCTGGAGCTGCGCGGCGGCGGCGACGCCCTGGGCCTGCGCCAGTCCGGCTTCCCGGACTACGCCTTCGCCGACCCC
ATCGCCCACCGCGACCTGATCGCCGCCGCCGGCGACGACGCGCGGCTCATCGTGATGCGCGACCCCGAGCTCGCCGGCGA
GCGCGGCAAGGCCCTGCAGGTGCTGCAGGAGCTGTTCGACTGGAAGGCGAACCTCGGGCTGAGGGACGCCGGCTAG

Upstream 100 bases:

>100_bases
CGCAGCTTCAGCTTCTTCTGCCGTGGATCATCTTCGGTCATCAGGAGGTCGCGGATATAGAGCCCCCCTCGCTCCGGCGC
CAGTCAGGTATGTTGCAATC

Downstream 100 bases:

>100_bases
ACCCGCACCATCCGCTTGCCGCGGTTCTCGCCGTGGAGCAGGCCGACGAGCGCCTGGGGCAGGTTCTCGAAGCCGTCGAT
GACGTCCTCCTGCACCTTGA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 691; Mature: 691

Protein sequence:

>691_residues
MRPEILFPLFAPITSLKGVGPRVAPLLEKVAGPIVRDVLWLKPHSLIRRTPAVLSAARDGETMTFEVAIHGYQAPRTKAQ
PWRVQVTDPTGFMTLVFFGRYGDQLAQRHPVGARRIVSGKVEESSFGRQMVHPDYILPPEKAGEIPELEAVYPATEGLPA
RRVRGFVLEALERAPELPEWQDPAFLRQEQFPAWRAAMERLHNPQSEADLSLLSPHRRRLAFDELLAHQLAMAQRKAARR
REPAARVAASETAEKIRADLPFRFTGAQERALAEIRADLSAGERMSRLVQGDVGSGKTVVAMCAMADVAASGGQSALMAP
TEILARQHYETISGPLAAHGVGTVLLTGRDKGAARREKLAALASGEARVAVGTHALFQDEVAFQKLQLVVIDEQHRFGVA
ERQRLQAKGEATHLIAMSATPIPRTLELTVYGDLDVSRIDEKPPGRTPVATRAAPMTRAHEVEARLREAVQGGAQAFWIC
PLVSESEATDLAAAERRAAELTERIGPSVGLVHGRLPPAAKDAVMAEFAEGRLSVLVATTVVEVGVNVPNATIMVIEQAE
RFGLAQLHQLRGRVGRGRRESACVLLYDPPLSETAQQRLDILRRTDDGFVIAEKDLELRGGGDALGLRQSGFPDYAFADP
IAHRDLIAAAGDDARLIVMRDPELAGERGKALQVLQELFDWKANLGLRDAG

Sequences:

>Translated_691_residues
MRPEILFPLFAPITSLKGVGPRVAPLLEKVAGPIVRDVLWLKPHSLIRRTPAVLSAARDGETMTFEVAIHGYQAPRTKAQ
PWRVQVTDPTGFMTLVFFGRYGDQLAQRHPVGARRIVSGKVEESSFGRQMVHPDYILPPEKAGEIPELEAVYPATEGLPA
RRVRGFVLEALERAPELPEWQDPAFLRQEQFPAWRAAMERLHNPQSEADLSLLSPHRRRLAFDELLAHQLAMAQRKAARR
REPAARVAASETAEKIRADLPFRFTGAQERALAEIRADLSAGERMSRLVQGDVGSGKTVVAMCAMADVAASGGQSALMAP
TEILARQHYETISGPLAAHGVGTVLLTGRDKGAARREKLAALASGEARVAVGTHALFQDEVAFQKLQLVVIDEQHRFGVA
ERQRLQAKGEATHLIAMSATPIPRTLELTVYGDLDVSRIDEKPPGRTPVATRAAPMTRAHEVEARLREAVQGGAQAFWIC
PLVSESEATDLAAAERRAAELTERIGPSVGLVHGRLPPAAKDAVMAEFAEGRLSVLVATTVVEVGVNVPNATIMVIEQAE
RFGLAQLHQLRGRVGRGRRESACVLLYDPPLSETAQQRLDILRRTDDGFVIAEKDLELRGGGDALGLRQSGFPDYAFADP
IAHRDLIAAAGDDARLIVMRDPELAGERGKALQVLQELFDWKANLGLRDAG
>Mature_691_residues
MRPEILFPLFAPITSLKGVGPRVAPLLEKVAGPIVRDVLWLKPHSLIRRTPAVLSAARDGETMTFEVAIHGYQAPRTKAQ
PWRVQVTDPTGFMTLVFFGRYGDQLAQRHPVGARRIVSGKVEESSFGRQMVHPDYILPPEKAGEIPELEAVYPATEGLPA
RRVRGFVLEALERAPELPEWQDPAFLRQEQFPAWRAAMERLHNPQSEADLSLLSPHRRRLAFDELLAHQLAMAQRKAARR
REPAARVAASETAEKIRADLPFRFTGAQERALAEIRADLSAGERMSRLVQGDVGSGKTVVAMCAMADVAASGGQSALMAP
TEILARQHYETISGPLAAHGVGTVLLTGRDKGAARREKLAALASGEARVAVGTHALFQDEVAFQKLQLVVIDEQHRFGVA
ERQRLQAKGEATHLIAMSATPIPRTLELTVYGDLDVSRIDEKPPGRTPVATRAAPMTRAHEVEARLREAVQGGAQAFWIC
PLVSESEATDLAAAERRAAELTERIGPSVGLVHGRLPPAAKDAVMAEFAEGRLSVLVATTVVEVGVNVPNATIMVIEQAE
RFGLAQLHQLRGRVGRGRRESACVLLYDPPLSETAQQRLDILRRTDDGFVIAEKDLELRGGGDALGLRQSGFPDYAFADP
IAHRDLIAAAGDDARLIVMRDPELAGERGKALQVLQELFDWKANLGLRDAG

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=680, Percent_Identity=43.0882352941177, Blast_Score=456, Evalue=1e-129,
Organism=Escherichia coli, GI1787357, Length=377, Percent_Identity=36.8700265251989, Blast_Score=232, Evalue=8e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 75384; Mature: 75384

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPEILFPLFAPITSLKGVGPRVAPLLEKVAGPIVRDVLWLKPHSLIRRTPAVLSAARDG
CCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCHHHHHHCCCC
ETMTFEVAIHGYQAPRTKAQPWRVQVTDPTGFMTLVFFGRYGDQLAQRHPVGARRIVSGK
CEEEEEEEEECCCCCCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHCCCCCHHHHCCC
VEESSFGRQMVHPDYILPPEKAGEIPELEAVYPATEGLPARRVRGFVLEALERAPELPEW
CCHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCCCC
QDPAFLRQEQFPAWRAAMERLHNPQSEADLSLLSPHRRRLAFDELLAHQLAMAQRKAARR
CCCHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
REPAARVAASETAEKIRADLPFRFTGAQERALAEIRADLSAGERMSRLVQGDVGSGKTVV
CCHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
AMCAMADVAASGGQSALMAPTEILARQHYETISGPLAAHGVGTVLLTGRDKGAARREKLA
HHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHCCCHHHCCCEEEEEECCCCCHHHHHHHH
ALASGEARVAVGTHALFQDEVAFQKLQLVVIDEQHRFGVAERQRLQAKGEATHLIAMSAT
HHHCCCCEEEECHHHHHHHHHHHHHEEEEEECCCHHCCHHHHHHHHHCCCCEEEEEEECC
PIPRTLELTVYGDLDVSRIDEKPPGRTPVATRAAPMTRAHEVEARLREAVQGGAQAFWIC
CCCCEEEEEEEECCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEE
PLVSESEATDLAAAERRAAELTERIGPSVGLVHGRLPPAAKDAVMAEFAEGRLSVLVATT
EECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCEEEHHHHH
VVEVGVNVPNATIMVIEQAERFGLAQLHQLRGRVGRGRRESACVLLYDPPLSETAQQRLD
HHHHCCCCCCCEEEEEECHHHCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHH
ILRRTDDGFVIAEKDLELRGGGDALGLRQSGFPDYAFADPIAHRDLIAAAGDDARLIVMR
HHHCCCCCEEEEECCEEECCCCCCCCCCCCCCCCCHHCCCHHHHHHHEECCCCEEEEEEE
DPELAGERGKALQVLQELFDWKANLGLRDAG
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRPEILFPLFAPITSLKGVGPRVAPLLEKVAGPIVRDVLWLKPHSLIRRTPAVLSAARDG
CCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCHHHHHHCCCC
ETMTFEVAIHGYQAPRTKAQPWRVQVTDPTGFMTLVFFGRYGDQLAQRHPVGARRIVSGK
CEEEEEEEEECCCCCCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHCCCCCHHHHCCC
VEESSFGRQMVHPDYILPPEKAGEIPELEAVYPATEGLPARRVRGFVLEALERAPELPEW
CCHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCCCC
QDPAFLRQEQFPAWRAAMERLHNPQSEADLSLLSPHRRRLAFDELLAHQLAMAQRKAARR
CCCHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
REPAARVAASETAEKIRADLPFRFTGAQERALAEIRADLSAGERMSRLVQGDVGSGKTVV
CCHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
AMCAMADVAASGGQSALMAPTEILARQHYETISGPLAAHGVGTVLLTGRDKGAARREKLA
HHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHCCCHHHCCCEEEEEECCCCCHHHHHHHH
ALASGEARVAVGTHALFQDEVAFQKLQLVVIDEQHRFGVAERQRLQAKGEATHLIAMSAT
HHHCCCCEEEECHHHHHHHHHHHHHEEEEEECCCHHCCHHHHHHHHHCCCCEEEEEEECC
PIPRTLELTVYGDLDVSRIDEKPPGRTPVATRAAPMTRAHEVEARLREAVQGGAQAFWIC
CCCCEEEEEEEECCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEE
PLVSESEATDLAAAERRAAELTERIGPSVGLVHGRLPPAAKDAVMAEFAEGRLSVLVATT
EECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCEEEHHHHH
VVEVGVNVPNATIMVIEQAERFGLAQLHQLRGRVGRGRRESACVLLYDPPLSETAQQRLD
HHHHCCCCCCCEEEEEECHHHCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHH
ILRRTDDGFVIAEKDLELRGGGDALGLRQSGFPDYAFADPIAHRDLIAAAGDDARLIVMR
HHHCCCCCEEEEECCEEECCCCCCCCCCCCCCCCCHHCCCHHHHHHHEECCCCEEEEEEE
DPELAGERGKALQVLQELFDWKANLGLRDAG
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]