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The map label for this gene is rfaD [H]

Identifier: 197105087

GI number: 197105087

Start: 1831088

End: 1832089

Strand: Reverse

Name: rfaD [H]

Synonym: PHZ_c1624

Alternate gene names: 197105087

Gene position: 1832089-1831088 (Counterclockwise)

Preceding gene: 197105088

Following gene: 197105086

Centisome position: 45.85

GC content: 68.56

Gene sequence:

>1002_bases
ATGACCCGCAAGATCGTCTTCGTGACCGGCGGCGCGGGCTTCATCGGCTCGAACATCGCCGCCAAGCTGGCCGAGGACCG
CAGCCTGGACGTCGTCGTCTGCGACCGGCTGCGTGAGGCCGAGCTCGGCAAGTGGCGCAACATCGCCAAGCACCCGATCG
GCGACTTCGTCGCGCCCGAGGACATGTTCGACTGGCTGGAGAAGCGCTGGCGCGACGTGGAGATGGTCGTCCACATGGCC
GCGGTCTCCTCCACGACCGAGCCCGACGCGGACAAGATCGTCCACTCGAACTTCACCCTCAGCCGCGACCTGTTCCGCTG
GTGCGCCGACCGGCAGCGCCGGTTCGTCTACGCCTCGTCGGCGGCCACCTACGGGGCGGGCGAGCACGGCTTCTCGGACG
ACAACGACTACGAGGCGCTGGCCCGGCTGCGACCGCTCAACACCTACGGCTGGTCGAAGGCGCTGTTCGACCTCTTCGCC
GTGCGCCAGGCGGGCCGCGACTACGCCCCGCCGCAGTGGGTGGGGCTGAAGTTCTTCAACGTCTACGGGCCCAACGAGGA
GCACAAGCACTCGATGAAGTCCGTGGCGGCGCAGATCTGGCCGCAGGTGCGCGAGGGCCACGCGGTGCAGCTCTTCAAGA
GCTACCGGCCCGACGTGCCGGACGGGGGCCAGAAGCGCGACTTCGTCTACGTCCGCGACGCCGCCGACGTGACCCGCTGG
CTGCTGGACAGCCCGCAGGTGAGCGGGGTCTTCAACCTGGGCTCGGGCCAGGCGCGGACCTTCGAGGAGATGGCGCGCAA
CGTCTTCGAGGCGGCGGGCAAGAACGCCCAGATCGAATACACGCCCATGCCGCCCGCCATCCGCGACAAGTACCAGTACT
TCACCCAGGCGCAGATGGACCGGCTGTTCGAGGCCGGCTACCCGGCCGCCATGACGCCGCTGGAGGAGGGGATCGGCGAC
TATGTCGGCAATTACCTCAGCCAGCCCGATCCCTACCGCTAG

Upstream 100 bases:

>100_bases
CCGAGCAGGTCCGGTCCTGGGGCGGCGAGGTGAAGCTCGCCAGCTTGGTGGACGGCTATTCCACCACCGCGGCCATCGCC
CGGATGAAGAAAGAGAAGGC

Downstream 100 bases:

>100_bases
GCGATGTCCGCAGGTCCGCGCTCGCGCCGCTGGCTGACCGCGGCCCTCCTGGGCCTGATCCTGCTGGTGGGCGCGGCGGT
GGGCTTCTACTGGGGCGACC

Product: ADP-L-glycero-D-mannoheptose-6-epimerase

Products: NA

Alternate protein names: ADP-L-glycero-beta-D-manno-heptose-6-epimerase; ADP-glyceromanno-heptose 6-epimerase; ADP-hep 6-epimerase; AGME [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTRKIVFVTGGAGFIGSNIAAKLAEDRSLDVVVCDRLREAELGKWRNIAKHPIGDFVAPEDMFDWLEKRWRDVEMVVHMA
AVSSTTEPDADKIVHSNFTLSRDLFRWCADRQRRFVYASSAATYGAGEHGFSDDNDYEALARLRPLNTYGWSKALFDLFA
VRQAGRDYAPPQWVGLKFFNVYGPNEEHKHSMKSVAAQIWPQVREGHAVQLFKSYRPDVPDGGQKRDFVYVRDAADVTRW
LLDSPQVSGVFNLGSGQARTFEEMARNVFEAAGKNAQIEYTPMPPAIRDKYQYFTQAQMDRLFEAGYPAAMTPLEEGIGD
YVGNYLSQPDPYR

Sequences:

>Translated_333_residues
MTRKIVFVTGGAGFIGSNIAAKLAEDRSLDVVVCDRLREAELGKWRNIAKHPIGDFVAPEDMFDWLEKRWRDVEMVVHMA
AVSSTTEPDADKIVHSNFTLSRDLFRWCADRQRRFVYASSAATYGAGEHGFSDDNDYEALARLRPLNTYGWSKALFDLFA
VRQAGRDYAPPQWVGLKFFNVYGPNEEHKHSMKSVAAQIWPQVREGHAVQLFKSYRPDVPDGGQKRDFVYVRDAADVTRW
LLDSPQVSGVFNLGSGQARTFEEMARNVFEAAGKNAQIEYTPMPPAIRDKYQYFTQAQMDRLFEAGYPAAMTPLEEGIGD
YVGNYLSQPDPYR
>Mature_332_residues
TRKIVFVTGGAGFIGSNIAAKLAEDRSLDVVVCDRLREAELGKWRNIAKHPIGDFVAPEDMFDWLEKRWRDVEMVVHMAA
VSSTTEPDADKIVHSNFTLSRDLFRWCADRQRRFVYASSAATYGAGEHGFSDDNDYEALARLRPLNTYGWSKALFDLFAV
RQAGRDYAPPQWVGLKFFNVYGPNEEHKHSMKSVAAQIWPQVREGHAVQLFKSYRPDVPDGGQKRDFVYVRDAADVTRWL
LDSPQVSGVFNLGSGQARTFEEMARNVFEAAGKNAQIEYTPMPPAIRDKYQYFTQAQMDRLFEAGYPAAMTPLEEGIGDY
VGNYLSQPDPYR

Specific function: Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose [H]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family. HldD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790049, Length=320, Percent_Identity=41.25, Blast_Score=225, Evalue=4e-60,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR011912
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.20 [H]

Molecular weight: Translated: 37791; Mature: 37660

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKIVFVTGGAGFIGSNIAAKLAEDRSLDVVVCDRLREAELGKWRNIAKHPIGDFVAPE
CCCEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
DMFDWLEKRWRDVEMVVHMAAVSSTTEPDADKIVHSNFTLSRDLFRWCADRQRRFVYASS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHEEEEECC
AATYGAGEHGFSDDNDYEALARLRPLNTYGWSKALFDLFAVRQAGRDYAPPQWVGLKFFN
CCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECEEEEE
VYGPNEEHKHSMKSVAAQIWPQVREGHAVQLFKSYRPDVPDGGQKRDFVYVRDAADVTRW
ECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHH
LLDSPQVSGVFNLGSGQARTFEEMARNVFEAAGKNAQIEYTPMPPAIRDKYQYFTQAQMD
HHCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHH
RLFEAGYPAAMTPLEEGIGDYVGNYLSQPDPYR
HHHHCCCCHHHCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TRKIVFVTGGAGFIGSNIAAKLAEDRSLDVVVCDRLREAELGKWRNIAKHPIGDFVAPE
CCEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
DMFDWLEKRWRDVEMVVHMAAVSSTTEPDADKIVHSNFTLSRDLFRWCADRQRRFVYASS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHEEEEECC
AATYGAGEHGFSDDNDYEALARLRPLNTYGWSKALFDLFAVRQAGRDYAPPQWVGLKFFN
CCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECEEEEE
VYGPNEEHKHSMKSVAAQIWPQVREGHAVQLFKSYRPDVPDGGQKRDFVYVRDAADVTRW
ECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHH
LLDSPQVSGVFNLGSGQARTFEEMARNVFEAAGKNAQIEYTPMPPAIRDKYQYFTQAQMD
HHCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHH
RLFEAGYPAAMTPLEEGIGDYVGNYLSQPDPYR
HHHHCCCCHHHCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]