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The map label for this gene is dnaC [H]

Identifier: 197105067

GI number: 197105067

Start: 1808941

End: 1809942

Strand: Reverse

Name: dnaC [H]

Synonym: PHZ_c1604

Alternate gene names: 197105067

Gene position: 1809942-1808941 (Counterclockwise)

Preceding gene: 197105068

Following gene: 197105066

Centisome position: 45.29

GC content: 75.55

Gene sequence:

>1002_bases
ATGGCTGAGGCCGCCGTCCCGCATCCCCGCGACGTCTACGAGCTGCGCGGGCAGGGGGGCGCCGAGGCCGCCTTCGAGGA
GGCCCGCGCCCGCTCGCGCCTGCACCACGCCTGGCTGCTGACCGGCCCCGAAGGCGTCGGCAAGGCCACCTTCGCCTACC
GCGCGGCGCGGCGCCTGCTGGGCGCGCCGCCGGCGCCGGCCTACGGCGAGCTGGGCTCGGATCCGAACCATCCCGTCAGC
CGTCAGGTGGCGGCCCGCAGCCATCCCGACCTGCTGGTGCTCGAGCGCGAGGGGCCCGACGGCAAGCCGCGCAAGGTGAT
CCCCGTCGAGGACGCCCGGCGCCTCGGCGAGTTCTTCTCCAAGTCGCCGGCCAGCGCGCCGCACCGGGTGGCGATCATCG
ACGCCGCCGACGACCTCAACGTCAACGCCGCCAACGCCATCCTGAAGACCCTGGAGGAGCCGCCGCCGCGCGGCGTGCTG
TTCATGGTCTCGCACTCGCCGGGACGGCTGCTGGCGACCATCCGCTCGCGCTGCCGCCGCCTGACCTTCCATCCTCTGGA
GCTGGAGGAGGCGGCCGCCTTCGTGCGCGCCCACGCCGACGTGAACGTCGAGGAGTCCCTGCGTCTTTCGCGCATGGCCG
GCGGCGCGCCGGGCCGGGCGCTGGCGCTCGCCGCCGCGGGCGCGCTCGCGGTGGACGACGCCGTGCGCGACCTGATCGCC
GACCTGCCCCGCGTGGACGAGACCCGGGCGCTGTCGCTGGCCGAGAAGTTCCGCGGCGGGGAGGGGCCCCAGGCCTTCGC
CCTGCTGTTCGACCGGCTGGCCGACCGGGTGCACGCCATGGCCACGGACCGTGCGGCCCAGGGGGTCGGCCCGCTTGATC
GCTGGGCCCAGGCGTGGGAGACGCTGCAGCGCCTGCCGCGCGAGGTCGAGGCCCTGAACCTCGATCGCACCGACGCGCTG
TTCGCCGCGCTTTCGGAACTTCGCCAGGCCGCCCAGGCCTAA

Upstream 100 bases:

>100_bases
GCCGCCGAGCCGCAGCGCTGCGCCGTCATCGACGCCACGGCGCCGATGGATGCGGTGGAGGGCGCCGTCTGGACGGCCGT
GTCCGAGCGGCTCGCCGTCC

Downstream 100 bases:

>100_bases
AGACCCATGCTGATCGACAGCCACGTCAACCTGCACGCGCCGCAATTCGACGACGACCGCGAGGCGGTCATCAGCCGGGC
CCTGGCCGCCGGCGTGCGGC

Product: DNA polymerase III, delta prime subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MAEAAVPHPRDVYELRGQGGAEAAFEEARARSRLHHAWLLTGPEGVGKATFAYRAARRLLGAPPAPAYGELGSDPNHPVS
RQVAARSHPDLLVLEREGPDGKPRKVIPVEDARRLGEFFSKSPASAPHRVAIIDAADDLNVNAANAILKTLEEPPPRGVL
FMVSHSPGRLLATIRSRCRRLTFHPLELEEAAAFVRAHADVNVEESLRLSRMAGGAPGRALALAAAGALAVDDAVRDLIA
DLPRVDETRALSLAEKFRGGEGPQAFALLFDRLADRVHAMATDRAAQGVGPLDRWAQAWETLQRLPREVEALNLDRTDAL
FAALSELRQAAQA

Sequences:

>Translated_333_residues
MAEAAVPHPRDVYELRGQGGAEAAFEEARARSRLHHAWLLTGPEGVGKATFAYRAARRLLGAPPAPAYGELGSDPNHPVS
RQVAARSHPDLLVLEREGPDGKPRKVIPVEDARRLGEFFSKSPASAPHRVAIIDAADDLNVNAANAILKTLEEPPPRGVL
FMVSHSPGRLLATIRSRCRRLTFHPLELEEAAAFVRAHADVNVEESLRLSRMAGGAPGRALALAAAGALAVDDAVRDLIA
DLPRVDETRALSLAEKFRGGEGPQAFALLFDRLADRVHAMATDRAAQGVGPLDRWAQAWETLQRLPREVEALNLDRTDAL
FAALSELRQAAQA
>Mature_332_residues
AEAAVPHPRDVYELRGQGGAEAAFEEARARSRLHHAWLLTGPEGVGKATFAYRAARRLLGAPPAPAYGELGSDPNHPVSR
QVAARSHPDLLVLEREGPDGKPRKVIPVEDARRLGEFFSKSPASAPHRVAIIDAADDLNVNAANAILKTLEEPPPRGVLF
MVSHSPGRLLATIRSRCRRLTFHPLELEEAAAFVRAHADVNVEESLRLSRMAGGAPGRALALAAAGALAVDDAVRDLIAD
LPRVDETRALSLAEKFRGGEGPQAFALLFDRLADRVHAMATDRAAQGVGPLDRWAQAWETLQRLPREVEALNLDRTDALF
AALSELRQAAQA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=275, Percent_Identity=28.7272727272727, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787341, Length=191, Percent_Identity=31.9371727748691, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003959
- InterPro:   IPR004622 [H]

Pfam domain/function: PF00004 AAA [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 35938; Mature: 35807

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEAAVPHPRDVYELRGQGGAEAAFEEARARSRLHHAWLLTGPEGVGKATFAYRAARRLL
CCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHH
GAPPAPAYGELGSDPNHPVSRQVAARSHPDLLVLEREGPDGKPRKVIPVEDARRLGEFFS
CCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCEEECHHHHHHHHHHHH
KSPASAPHRVAIIDAADDLNVNAANAILKTLEEPPPRGVLFMVSHSPGRLLATIRSRCRR
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHH
LTFHPLELEEAAAFVRAHADVNVEESLRLSRMAGGAPGRALALAAAGALAVDDAVRDLIA
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DLPRVDETRALSLAEKFRGGEGPQAFALLFDRLADRVHAMATDRAAQGVGPLDRWAQAWE
HCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
TLQRLPREVEALNLDRTDALFAALSELRQAAQA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEAAVPHPRDVYELRGQGGAEAAFEEARARSRLHHAWLLTGPEGVGKATFAYRAARRLL
CCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHH
GAPPAPAYGELGSDPNHPVSRQVAARSHPDLLVLEREGPDGKPRKVIPVEDARRLGEFFS
CCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCEEECHHHHHHHHHHHH
KSPASAPHRVAIIDAADDLNVNAANAILKTLEEPPPRGVLFMVSHSPGRLLATIRSRCRR
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHH
LTFHPLELEEAAAFVRAHADVNVEESLRLSRMAGGAPGRALALAAAGALAVDDAVRDLIA
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DLPRVDETRALSLAEKFRGGEGPQAFALLFDRLADRVHAMATDRAAQGVGPLDRWAQAWE
HCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
TLQRLPREVEALNLDRTDALFAALSELRQAAQA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550441; 10984043 [H]