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The map label for this gene is yabD [H]

Identifier: 197105066

GI number: 197105066

Start: 1808158

End: 1808934

Strand: Reverse

Name: yabD [H]

Synonym: PHZ_c1603

Alternate gene names: 197105066

Gene position: 1808934-1808158 (Counterclockwise)

Preceding gene: 197105067

Following gene: 197105065

Centisome position: 45.27

GC content: 71.17

Gene sequence:

>777_bases
ATGCTGATCGACAGCCACGTCAACCTGCACGCGCCGCAATTCGACGACGACCGCGAGGCGGTCATCAGCCGGGCCCTGGC
CGCCGGCGTGCGGCTGATGGTCAACATCTGCGACCGGGTCTCGAACTTCGATGCGGTCCGCGCCGTGGCCATGCACCCGG
ACATCTGGTGCACCGTCGGAACCCATCCGCACGAGGCCAAGGAGAACCCCGACCTGGCGGCCCGCACCCTGGTCGAGCTG
GCCCAGGACCCGCGCGTCGTCGGCATCGGCGAATGCGGCCTCGACTTCCACTACGACCTCAGCCCGCGGGACATCCAGGC
GAAGGTCTTCCGCGTCCACTGCGAGGCGGCGCGCGAGACGGGCCTCCCGCTCGTGGTCCACACCCGCGAGGCCGACGAGG
TGATGGGCCGGATCCTGGCCGAGGAGCACGCCCGCGGGCCGTTCCGCATCCTGATGCACTGCTACACCTCGGGCGCCGAA
CTGGCCCGCCAGGCGGCCGAGCTGGGCGCCTGGTTCTCTGTGGCCGGCATCGCCACGTTCAAGACCGCCGACGACGTGCG
CGCGGTGATCCGCGACATGCCGGCCGACCGCATCATCGTCGAGACCGACTGCCCCTACCTCGCGCCCGTGCCCTACCGCG
GGCGGCGCAACGAGCCGGCCTTCCTGCCGCACGTTCTGGCCAGACTGGCCGAGATCCGCGGCTGGGGCCTGGACGAGGCC
GAGCAGCGCACCGAGGACGCCTTCTTCGCCCTGTTCGACCGGATTCCCCGGCCATGA

Upstream 100 bases:

>100_bases
GCGCCTGCCGCGCGAGGTCGAGGCCCTGAACCTCGATCGCACCGACGCGCTGTTCGCCGCGCTTTCGGAACTTCGCCAGG
CCGCCCAGGCCTAAAGACCC

Downstream 100 bases:

>100_bases
GCGCGACGCTCGAGGTCGTGATCCTGGGCTGCGGCTCGTCGGGCGGGGTGCCGCGGGCCGACGGCGAATGGGGCGACTGC
GACCCGGCCAATCCGAAGAA

Product: urease/pyrimidinase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MLIDSHVNLHAPQFDDDREAVISRALAAGVRLMVNICDRVSNFDAVRAVAMHPDIWCTVGTHPHEAKENPDLAARTLVEL
AQDPRVVGIGECGLDFHYDLSPRDIQAKVFRVHCEAARETGLPLVVHTREADEVMGRILAEEHARGPFRILMHCYTSGAE
LARQAAELGAWFSVAGIATFKTADDVRAVIRDMPADRIIVETDCPYLAPVPYRGRRNEPAFLPHVLARLAEIRGWGLDEA
EQRTEDAFFALFDRIPRP

Sequences:

>Translated_258_residues
MLIDSHVNLHAPQFDDDREAVISRALAAGVRLMVNICDRVSNFDAVRAVAMHPDIWCTVGTHPHEAKENPDLAARTLVEL
AQDPRVVGIGECGLDFHYDLSPRDIQAKVFRVHCEAARETGLPLVVHTREADEVMGRILAEEHARGPFRILMHCYTSGAE
LARQAAELGAWFSVAGIATFKTADDVRAVIRDMPADRIIVETDCPYLAPVPYRGRRNEPAFLPHVLARLAEIRGWGLDEA
EQRTEDAFFALFDRIPRP
>Mature_258_residues
MLIDSHVNLHAPQFDDDREAVISRALAAGVRLMVNICDRVSNFDAVRAVAMHPDIWCTVGTHPHEAKENPDLAARTLVEL
AQDPRVVGIGECGLDFHYDLSPRDIQAKVFRVHCEAARETGLPLVVHTREADEVMGRILAEEHARGPFRILMHCYTSGAE
LARQAAELGAWFSVAGIATFKTADDVRAVIRDMPADRIIVETDCPYLAPVPYRGRRNEPAFLPHVLARLAEIRGWGLDEA
EQRTEDAFFALFDRIPRP

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=272, Percent_Identity=26.8382352941176, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI225903424, Length=181, Percent_Identity=31.4917127071823, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI225903439, Length=219, Percent_Identity=26.4840182648402, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI110349730, Length=272, Percent_Identity=25.3676470588235, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI110349734, Length=272, Percent_Identity=25.3676470588235, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI226061853, Length=277, Percent_Identity=24.9097472924188, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI226061614, Length=257, Percent_Identity=24.9027237354086, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI226061595, Length=231, Percent_Identity=25.5411255411255, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787342, Length=256, Percent_Identity=33.984375, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI48994985, Length=239, Percent_Identity=32.6359832635983, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI87082439, Length=255, Percent_Identity=27.4509803921569, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17559024, Length=215, Percent_Identity=33.4883720930233, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71980746, Length=250, Percent_Identity=26, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17565396, Length=215, Percent_Identity=31.1627906976744, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17543026, Length=202, Percent_Identity=29.7029702970297, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648690, Length=282, Percent_Identity=30.1418439716312, Blast_Score=97, Evalue=7e-21,
Organism=Drosophila melanogaster, GI221330018, Length=251, Percent_Identity=28.2868525896414, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24586117, Length=227, Percent_Identity=29.0748898678414, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28805; Mature: 28805

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS01090 TATD_2 ; PS01091 TATD_3 ; PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDSHVNLHAPQFDDDREAVISRALAAGVRLMVNICDRVSNFDAVRAVAMHPDIWCTVG
CEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEECCCEEEEEC
THPHEAKENPDLAARTLVELAQDPRVVGIGECGLDFHYDLSPRDIQAKVFRVHCEAARET
CCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHC
GLPLVVHTREADEVMGRILAEEHARGPFRILMHCYTSGAELARQAAELGAWFSVAGIATF
CCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHH
KTADDVRAVIRDMPADRIIVETDCPYLAPVPYRGRRNEPAFLPHVLARLAEIRGWGLDEA
CCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHH
EQRTEDAFFALFDRIPRP
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLIDSHVNLHAPQFDDDREAVISRALAAGVRLMVNICDRVSNFDAVRAVAMHPDIWCTVG
CEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEECCCEEEEEC
THPHEAKENPDLAARTLVELAQDPRVVGIGECGLDFHYDLSPRDIQAKVFRVHCEAARET
CCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHC
GLPLVVHTREADEVMGRILAEEHARGPFRILMHCYTSGAELARQAAELGAWFSVAGIATF
CCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHH
KTADDVRAVIRDMPADRIIVETDCPYLAPVPYRGRRNEPAFLPHVLARLAEIRGWGLDEA
CCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHH
EQRTEDAFFALFDRIPRP
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]