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The map label for this gene is frpC [H]

Identifier: 197104932

GI number: 197104932

Start: 1667168

End: 1668652

Strand: Reverse

Name: frpC [H]

Synonym: PHZ_c1467

Alternate gene names: 197104932

Gene position: 1668652-1667168 (Counterclockwise)

Preceding gene: 197104933

Following gene: 197104931

Centisome position: 41.76

GC content: 71.99

Gene sequence:

>1485_bases
ATGTCGCACAAGCTTTCCCATGACTGGAGGGATACCCCCATCCAGGAACTGGCAAATAGATATCTGTCCGAAGGCGGATT
CACCTTTGACTTCGACGCCGGTCGGGCGCGCTACAACTACCAGGTGTCCGTCGGCGACAATGGACGCGACGCCTTGGCCG
GGCGCGGCGACCGCGACCACTTCTGGGGCCTCGGCGGGGACGACCAGTTGTCGGGCTCACGCGAGAACGACGTGCTGTAC
GGCGACGCCGGGGCCGACACGCTGAGCGGCGGTGACGGCGCCGACCGCCTCACGGGCGGCCTGGACGGCGACCGGCTCTA
CGGCGGCGCGGACGCGGACGCCCTGATGGGCGGCATGGGCGACGACCACCTCGACGAAGGGGCTGGGCACGGCGACCTCC
AGGGCGGCATGGGCGACGATACCCTGGTCGGCGGCGCGGGGCCCGACGCCTTCGCCGTCGATCCGACGAGCGGGAACGAC
GTGATCCGCGACTTCACCGCCGGGCCCGGCATGTTCGACCACCTGGCCTTGCGGGACCTGCGCTGGGAGGACCTCAGCTT
CGTGGACACCGCCGCCGGCGTGCGGGTCAGCTGGAACGGCGGCTCGGTGCTGCTGGAGGGCGTGCGTCAGGCCGACCTCG
CGCAGGACGATTTCATGTTCGCCGAGGAGCCCGATCTGCCGCCGGCGTCGCGGGAGGCGAGCGGGCCCACCGCCGAGCGG
GCGACGCCCAGCGTCGAGGGCCCGGCCCTCCGGCGCGGCGACCTCCCCGGCGAGCGCTTCGACCAGGCGGCGGACGCGAC
CCTGCGGGACGGCCACCTGACCCTCGCCTTCGCCGGCGACGAGCCCTACCAGGTGATCGTCGGCGATCGTGACGGCGACG
AACTGACCGGAGCCGCGGGCGCCGACAACATCTTCGGGCGGGATGGCGACGACAGCCTCGACGGAGCGGGCGGCGACGAT
GTCCTGCAAGGCGACGCCGGCGACGACCGGCTCGACGGCGGCGACGGGATGGACCGGCTGGACGGCGGGATGGGCGCTGA
CACGCTCACGGGCGGCGCCATGGTCGACGACATCATGGGCATGGACGGGGCGGACTCGATCGGCGCCGGCGCCGGCCACG
ACATGGTCGAAGGCGGGATGGGGAATGACACGATCGCCGGCGGCCCGGGCGCCGACGCCTTCATCGTCGATCCGCACAGC
GGCTTCGACGTGATCCTCGACATGGAGGTGCGTGGCGAGGCGCAGGGCGCGTTCGACCACCTGGCGCTGCGCGACATCCG
TCCCGACCAGGTCACCGTCGTCGACCGGGCGGAGGGGGCCTTCGTCTCCTGGAACACCGACCGCGACGCCGATCCCGAGG
GCGGGGTCCTGCTGCAGGGGGTGTTCAAGGCGGACCTGCGGCAGAGCGACTTCATGTTCGTGGAGGAGCCCGGCTTCGTC
CCGGGGATCAGCGACGCAGGGTCGGACTGGATCTTCCCGGGCTGA

Upstream 100 bases:

>100_bases
AACTCGGCGGGCCAAGACCAGTTGGGGAGTCGCCGCGATGTCGTTGAGATGACGCGGCAGCAAAACCTTCCCACCACTGC
AATGCGCGCCGAGGTTCACC

Downstream 100 bases:

>100_bases
GGCCGGGCTGAGGCTGCACGCCCGAGGAGGAGGGGTCGGCGGGCGCCGCGCATGCGGGTGCAGCGAAGGAGGCTGAATGA
CCACGCGCTCGTCGTTGCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MSHKLSHDWRDTPIQELANRYLSEGGFTFDFDAGRARYNYQVSVGDNGRDALAGRGDRDHFWGLGGDDQLSGSRENDVLY
GDAGADTLSGGDGADRLTGGLDGDRLYGGADADALMGGMGDDHLDEGAGHGDLQGGMGDDTLVGGAGPDAFAVDPTSGND
VIRDFTAGPGMFDHLALRDLRWEDLSFVDTAAGVRVSWNGGSVLLEGVRQADLAQDDFMFAEEPDLPPASREASGPTAER
ATPSVEGPALRRGDLPGERFDQAADATLRDGHLTLAFAGDEPYQVIVGDRDGDELTGAAGADNIFGRDGDDSLDGAGGDD
VLQGDAGDDRLDGGDGMDRLDGGMGADTLTGGAMVDDIMGMDGADSIGAGAGHDMVEGGMGNDTIAGGPGADAFIVDPHS
GFDVILDMEVRGEAQGAFDHLALRDIRPDQVTVVDRAEGAFVSWNTDRDADPEGGVLLQGVFKADLRQSDFMFVEEPGFV
PGISDAGSDWIFPG

Sequences:

>Translated_494_residues
MSHKLSHDWRDTPIQELANRYLSEGGFTFDFDAGRARYNYQVSVGDNGRDALAGRGDRDHFWGLGGDDQLSGSRENDVLY
GDAGADTLSGGDGADRLTGGLDGDRLYGGADADALMGGMGDDHLDEGAGHGDLQGGMGDDTLVGGAGPDAFAVDPTSGND
VIRDFTAGPGMFDHLALRDLRWEDLSFVDTAAGVRVSWNGGSVLLEGVRQADLAQDDFMFAEEPDLPPASREASGPTAER
ATPSVEGPALRRGDLPGERFDQAADATLRDGHLTLAFAGDEPYQVIVGDRDGDELTGAAGADNIFGRDGDDSLDGAGGDD
VLQGDAGDDRLDGGDGMDRLDGGMGADTLTGGAMVDDIMGMDGADSIGAGAGHDMVEGGMGNDTIAGGPGADAFIVDPHS
GFDVILDMEVRGEAQGAFDHLALRDIRPDQVTVVDRAEGAFVSWNTDRDADPEGGVLLQGVFKADLRQSDFMFVEEPGFV
PGISDAGSDWIFPG
>Mature_493_residues
SHKLSHDWRDTPIQELANRYLSEGGFTFDFDAGRARYNYQVSVGDNGRDALAGRGDRDHFWGLGGDDQLSGSRENDVLYG
DAGADTLSGGDGADRLTGGLDGDRLYGGADADALMGGMGDDHLDEGAGHGDLQGGMGDDTLVGGAGPDAFAVDPTSGNDV
IRDFTAGPGMFDHLALRDLRWEDLSFVDTAAGVRVSWNGGSVLLEGVRQADLAQDDFMFAEEPDLPPASREASGPTAERA
TPSVEGPALRRGDLPGERFDQAADATLRDGHLTLAFAGDEPYQVIVGDRDGDELTGAAGADNIFGRDGDDSLDGAGGDDV
LQGDAGDDRLDGGDGMDRLDGGMGADTLTGGAMVDDIMGMDGADSIGAGAGHDMVEGGMGNDTIAGGPGADAFIVDPHSG
FDVILDMEVRGEAQGAFDHLALRDIRPDQVTVVDRAEGAFVSWNTDRDADPEGGVLLQGVFKADLRQSDFMFVEEPGFVP
GISDAGSDWIFPG

Specific function: May participate in the pathogenesis of meningococcal disease [H]

COG id: COG2931

COG function: function code Q; RTX toxins and related Ca2+-binding proteins

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Secreted (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 22 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010566
- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF06594 HCBP_related; PF00353 HemolysinCabind [H]

EC number: NA

Molecular weight: Translated: 51401; Mature: 51270

Theoretical pI: Translated: 3.81; Mature: 3.81

Prosite motif: PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHKLSHDWRDTPIQELANRYLSEGGFTFDFDAGRARYNYQVSVGDNGRDALAGRGDRDH
CCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCEEEEEEEEECCCCCHHHCCCCCCCC
FWGLGGDDQLSGSRENDVLYGDAGADTLSGGDGADRLTGGLDGDRLYGGADADALMGGMG
CCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHCCCCCCCEEECCCCHHHHHCCCC
DDHLDEGAGHGDLQGGMGDDTLVGGAGPDAFAVDPTSGNDVIRDFTAGPGMFDHLALRDL
CCHHHCCCCCCCCCCCCCCCCEECCCCCCCEEECCCCCCHHHHHCCCCCCHHHHHHHHHC
RWEDLSFVDTAAGVRVSWNGGSVLLEGVRQADLAQDDFMFAEEPDLPPASREASGPTAER
CCCCCCCEECCCCEEEEECCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCHHH
ATPSVEGPALRRGDLPGERFDQAADATLRDGHLTLAFAGDEPYQVIVGDRDGDELTGAAG
CCCCCCCCCCCCCCCCHHHHHHHHCCEEECCEEEEEEECCCCEEEEEECCCCCCCCCCCC
ADNIFGRDGDDSLDGAGGDDVLQGDAGDDRLDGGDGMDRLDGGMGADTLTGGAMVDDIMG
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHC
MDGADSIGAGAGHDMVEGGMGNDTIAGGPGADAFIVDPHSGFDVILDMEVRGEAQGAFDH
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEEEECCCCCCCHHH
LALRDIRPDQVTVVDRAEGAFVSWNTDRDADPEGGVLLQGVFKADLRQSDFMFVEEPGFV
HHHHCCCCCEEEEEECCCCCEEEECCCCCCCCCCCEEEEEHHHHHCCCCCEEEEECCCCC
PGISDAGSDWIFPG
CCCCCCCCCCCCCC
>Mature Secondary Structure 
SHKLSHDWRDTPIQELANRYLSEGGFTFDFDAGRARYNYQVSVGDNGRDALAGRGDRDH
CCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCEEEEEEEEECCCCCHHHCCCCCCCC
FWGLGGDDQLSGSRENDVLYGDAGADTLSGGDGADRLTGGLDGDRLYGGADADALMGGMG
CCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHCCCCCCCEEECCCCHHHHHCCCC
DDHLDEGAGHGDLQGGMGDDTLVGGAGPDAFAVDPTSGNDVIRDFTAGPGMFDHLALRDL
CCHHHCCCCCCCCCCCCCCCCEECCCCCCCEEECCCCCCHHHHHCCCCCCHHHHHHHHHC
RWEDLSFVDTAAGVRVSWNGGSVLLEGVRQADLAQDDFMFAEEPDLPPASREASGPTAER
CCCCCCCEECCCCEEEEECCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCHHH
ATPSVEGPALRRGDLPGERFDQAADATLRDGHLTLAFAGDEPYQVIVGDRDGDELTGAAG
CCCCCCCCCCCCCCCCHHHHHHHHCCEEECCEEEEEEECCCCEEEEEECCCCCCCCCCCC
ADNIFGRDGDDSLDGAGGDDVLQGDAGDDRLDGGDGMDRLDGGMGADTLTGGAMVDDIMG
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHC
MDGADSIGAGAGHDMVEGGMGNDTIAGGPGADAFIVDPHSGFDVILDMEVRGEAQGAFDH
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEEEECCCCCCCHHH
LALRDIRPDQVTVVDRAEGAFVSWNTDRDADPEGGVLLQGVFKADLRQSDFMFVEEPGFV
HHHHCCCCCEEEEEECCCCCEEEECCCCCCCCCCCEEEEEHHHHHCCCCCEEEEECCCCC
PGISDAGSDWIFPG
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]