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The map label for this gene is hmrR2 [H]

Identifier: 197104933

GI number: 197104933

Start: 1668795

End: 1669229

Strand: Reverse

Name: hmrR2 [H]

Synonym: PHZ_c1468

Alternate gene names: 197104933

Gene position: 1669229-1668795 (Counterclockwise)

Preceding gene: 197104934

Following gene: 197104932

Centisome position: 41.77

GC content: 68.97

Gene sequence:

>435_bases
ATGAACATCGGCCAAGCCTCCAAGGCGTCGGGCGTCACCGCCAAGATGATCCGCTACTACGACGAGATCGGGTTGGTGCA
GCCGGCCAGCCGCACCGACTCCAACTACCGCGAGTACGGCGAGCGGGAGATCAACGAACTCCGGTTCATCAAACGGGCGC
GCAGCCTCGGCTTCTCCATGGTCGAGATCACCCAGTTGCTCTCGCTGTGGCGCGACCGCGAGCGGCCGAGCCGCGACGTG
AAGGCGATCGCCGACCGCCACCTGGGCGACCTGGAGGCGCGCATCGCCGAAATGCAGGCGATGGCCGACACGCTGCGCCA
CCTGTCCCACTGCTGCGCCGGCGACGACCGGCCGGACTGCCCGATCCTCGCCGACCTCACCGGCGGAAAGGAGCCGGGGC
CGGTACGCCCGAAACGGCGCCGCTTCGGGCGATGA

Upstream 100 bases:

>100_bases
CCAGCGTCAGCGTGCTCGCCAACGCCCTGCGCCTGCGGCGCTTCCGGCCCGCAGCCCGCTCAGGGTCAGCCCCACGCCTC
AGCTCCGAAGGAGCCCCCGC

Downstream 100 bases:

>100_bases
AACAATTGAGGGCGAGGACCGGACTCTTCTGATCCGGGCCGGAACTCGGCGGGCCAAGACCAGTTGGGGAGTCGCCGCGA
TGTCGTTGAGATGACGCGGC

Product: transcriptional regulator, MerR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MNIGQASKASGVTAKMIRYYDEIGLVQPASRTDSNYREYGEREINELRFIKRARSLGFSMVEITQLLSLWRDRERPSRDV
KAIADRHLGDLEARIAEMQAMADTLRHLSHCCAGDDRPDCPILADLTGGKEPGPVRPKRRRFGR

Sequences:

>Translated_144_residues
MNIGQASKASGVTAKMIRYYDEIGLVQPASRTDSNYREYGEREINELRFIKRARSLGFSMVEITQLLSLWRDRERPSRDV
KAIADRHLGDLEARIAEMQAMADTLRHLSHCCAGDDRPDCPILADLTGGKEPGPVRPKRRRFGR
>Mature_144_residues
MNIGQASKASGVTAKMIRYYDEIGLVQPASRTDSNYREYGEREINELRFIKRARSLGFSMVEITQLLSLWRDRERPSRDV
KAIADRHLGDLEARIAEMQAMADTLRHLSHCCAGDDRPDCPILADLTGGKEPGPVRPKRRRFGR

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=128, Percent_Identity=41.40625, Blast_Score=115, Evalue=1e-27,
Organism=Escherichia coli, GI1789687, Length=130, Percent_Identity=37.6923076923077, Blast_Score=86, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16373; Mature: 16373

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGQASKASGVTAKMIRYYDEIGLVQPASRTDSNYREYGEREINELRFIKRARSLGFSM
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
VEITQLLSLWRDRERPSRDVKAIADRHLGDLEARIAEMQAMADTLRHLSHCCAGDDRPDC
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PILADLTGGKEPGPVRPKRRRFGR
CEEEECCCCCCCCCCCHHHHCCCC
>Mature Secondary Structure
MNIGQASKASGVTAKMIRYYDEIGLVQPASRTDSNYREYGEREINELRFIKRARSLGFSM
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
VEITQLLSLWRDRERPSRDVKAIADRHLGDLEARIAEMQAMADTLRHLSHCCAGDDRPDC
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PILADLTGGKEPGPVRPKRRRFGR
CEEEECCCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]